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Tag Content
UUCD2 ID IUUC-Sha-106905
UUCD1 version UUC-SaH-00545
Ensembl Protein ID ENSSHAP00000013145.1
UniProt Accession G3WCJ0; G3WCJ0_SARHA
Genbank Protein ID ENSSHAP00000013145
Protein Name Coatomer subunit beta'
Genbank Nucleotide ID AEFK01108453
Gene Name COPB2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSHAG00000011236.1 ENSSHAT00000013251.1 ENSSHAP00000013145.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.10e-33 114.0 183 224
UBD/Beta-Prp 9.70e-72 241.8 13 292
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD  +k+WD+   +++++
   Q: 183  GHEKGVNCIDYysgGDkPYLISGADDRLVKIWDYQNKTCVQT 224
           8*********9999778****************999988875 PP
   

   UBD/Beta-Prp
   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++++++++v+ +p +++++++ ++g++ vw+ +t++l+++++ ++ +v+a kf  ++++ vtg++D+ i+v++++t + vh +++h+d+
   Q: 13   ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDY 101
           67899************************************************************************************ PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +++++++p++ ++++ s+d  i++wd+++++  +++++gh++ v+ +v++p++ n ++s+slDrt+++W+l + +   tl+g h++ v+
   Q: 102  IRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVN 189
           *******************************9999**********************************************9.****** PP
   S: 185  slsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           ++++ s g  ++l+sg++d+ vk+wd+q+++cv+tl+gh +nv++  f+p+  ++++gs+Dg++riW + +  l +tl++  ++v++va
   Q: 190  CIDYYSGGdkPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVA 278
           ***8887777******************************************************************************* PP
   S: 272  vlsfgdnvlvlgse 285
            l+ ++nv +  +e
   Q: 279  SLRGSNNVALGYDE 292
           *9999998755544 PP
   
Organism Sarcophilus harrisii
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Protein Sequence
(Fasta)
MPLRLDIKRK LTARSDRVKS VDLHPTEPWM LASLYNGSVC VWNHETQTLV KTFEVCDLPV 60
RAAKFVARKN WVVTGADDMQ IRVFNYNTLE RVHMFEAHSD YIRCIAVHPT QPFILTSSDD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sha-106905|E3,WD_repeat;UBD,Beta-Prp|Sarcophilus harrisii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGTGAGAC CTTGGCCTTG CAGGATTAAA ATTTAATAAG TAGATGAAAG CGCGGCGCGC 60
GTTGGTGCTG ACCCCACAGG GGTTGCCGTA GGCGGGGCTG CTCCGGGGAG CTCCTGTGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sha-106905|E3,WD_repeat;UBD,Beta-Prp|Sarcophilus harrisii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04053--Coatomer_WDAD
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:1901998--P:toxin transport
KEGG shr:100930074
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000654 Aegilops tauschii 52.04 0.00e+00 950.00
IUUC-Aml-002154 Ailuropoda melanoleuca 94.40 0.00e+00 1766.00
IUUC-Atr-003090 Amborella trichopoda 59.01 0.00e+00 1081.00
IUUC-Apl-003976 Anas platyrhynchos 95.30 0.00e+00 1748.00
IUUC-Aca-004301 Anolis carolinensis 97.63 0.00e+00 1734.00
IUUC-Aly-006508 Arabidopsis lyrata 60.36 0.00e+00 1100.00
IUUC-Ath-007630 Arabidopsis thaliana 61.82 0.00e+00 1108.00
IUUC-Ago-007914 Ashbya gossypii 46.19 0.00e+00 759.00
IUUC-Acl-008237 Aspergillus clavatus 56.76 0.00e+00 972.00
IUUC-Afl-008535 Aspergillus flavus 55.96 0.00e+00 917.00
IUUC-Afu-008845 Aspergillus fumigatus 55.07 0.00e+00 947.00
IUUC-Ani-009135 Aspergillus nidulans 56.21 0.00e+00 922.00
IUUC-Ang-009654 Aspergillus niger 56.47 0.00e+00 867.00
IUUC-Aor-009939 Aspergillus oryzae 53.65 0.00e+00 976.00
IUUC-Ate-010355 Aspergillus terreus 54.21 0.00e+00 920.00
IUUC-Ame-010922 Astyanax mexicanus 84.68 0.00e+00 1510.00
IUUC-Bgr-012249 Blumeria graminis 54.10 0.00e+00 944.00
IUUC-Bta-013579 Bos taurus 99.02 0.00e+00 1483.00
IUUC-Bci-013866 Botrytis cinerea 55.79 0.00e+00 930.00
IUUC-Bdi-015046 Brachypodium distachyon 61.33 0.00e+00 1114.00
IUUC-Bol-016271 Brassica oleracea 60.71 0.00e+00 1116.00
IUUC-Bra-017758 Brassica rapa 60.66 0.00e+00 1115.00
IUUC-Cel-018387 Caenorhabditis elegans 64.10 0.00e+00 1187.00
IUUC-Cja-019145 Callithrix jacchus 95.18 0.00e+00 1778.00
IUUC-Cfa-020564 Canis familiaris 95.18 0.00e+00 1771.00
IUUC-Cpo-022201 Cavia porcellus 94.30 0.00e+00 1760.00
IUUC-Cre-022938 Chlamydomonas reinhardtii 58.67 0.00e+00 993.00
IUUC-Csa-023383 Chlorocebus sabaeus 98.06 0.00e+00 1179.00
IUUC-Cho-024454 Choloepus hoffmanni 92.24 0.00e+00 1406.00
IUUC-Cin-025681 Ciona intestinalis 77.94 0.00e+00 1374.00
IUUC-Csv-026012 Ciona savignyi 72.40 0.00e+00 1348.00
IUUC-Cgl-026649 Colletotrichum gloeosporioides 52.34 0.00e+00 849.00
IUUC-Cne-026986 Cryptococcus neoformans 51.69 0.00e+00 922.00
IUUC-Cme-027219 Cyanidioschyzon merolae 48.21 0.00e+00 853.00
IUUC-Dre-027846 Danio rerio 93.88 0.00e+00 1692.00
IUUC-Dor-030462 Dipodomys ordii 92.48 0.00e+00 1269.00
IUUC-Dse-031268 Dothistroma septosporum 55.21 0.00e+00 957.00
IUUC-Dme-031791 Drosophila melanogaster 72.52 0.00e+00 1277.00
IUUC-Ete-033166 Echinops telfairi 88.35 0.00e+00 1014.00
IUUC-Eca-034180 Equus caballus 92.98 0.00e+00 1699.00
IUUC-Eeu-035086 Erinaceus europaeus 81.35 0.00e+00 855.00
IUUC-Fca-036265 Felis catus 94.63 0.00e+00 1769.00
IUUC-Fal-037202 Ficedula albicollis 96.52 0.00e+00 1689.00
IUUC-Fox-037711 Fusarium oxysporum 56.70 0.00e+00 893.00
IUUC-Fso-038268 Fusarium solani 56.20 0.00e+00 890.00
IUUC-Gmo-039046 Gadus morhua 93.25 0.00e+00 1668.00
IUUC-Ggr-039863 Gaeumannomyces graminis 55.42 0.00e+00 909.00
IUUC-Gga-041112 Gallus gallus 95.31 0.00e+00 1747.00
IUUC-Gac-041733 Gasterosteus aculeatus 92.10 0.00e+00 1629.00
IUUC-Gma-042910 Glycine max 62.71 0.00e+00 1123.00
IUUC-Ggo-044984 Gorilla gorilla 94.41 0.00e+00 1769.00
IUUC-Hsa-046698 Homo sapiens 94.63 0.00e+00 1770.00
IUUC-Hvu-047669 Hordeum vulgare 70.90 4.00e-169 587.00
IUUC-Itr-048212 Ictidomys tridecemlineatus 93.96 0.00e+00 1751.00
IUUC-Kpa-049265 Komagataella pastoris 49.19 0.00e+00 864.00
IUUC-Lch-050473 Latimeria chalumnae 91.29 0.00e+00 1732.00
IUUC-Lpe-051579 Leersia perrieri 61.29 0.00e+00 1104.00
IUUC-Loc-052675 Lepisosteus oculatus 95.16 0.00e+00 1707.00
IUUC-Lma-053218 Leptosphaeria maculans 54.49 0.00e+00 931.00
IUUC-Laf-053757 Loxodonta africana 94.75 0.00e+00 1761.00
IUUC-Mcc-054859 Macaca mulatta 95.07 0.00e+00 1776.00
IUUC-Meu-056174 Macropus eugenii 98.96 0.00e+00 777.00
IUUC-Mor-057264 Magnaporthe oryzae 55.97 0.00e+00 894.00
IUUC-Mpo-057538 Magnaporthe poae 55.67 0.00e+00 924.00
IUUC-Mtr-058310 Medicago truncatula 62.83 0.00e+00 1132.00
IUUC-Mla-058937 Melampsora laricipopulina 54.21 0.00e+00 917.00
IUUC-Mga-059875 Meleagris gallopavo 95.09 0.00e+00 1741.00
IUUC-Mvi-060240 Microbotryum violaceum 50.06 0.00e+00 919.00
IUUC-Mmr-061261 Microcebus murinus 95.29 0.00e+00 1780.00
IUUC-Mdo-062076 Monodelphis domestica 98.87 0.00e+00 1820.00
IUUC-Mmu-063324 Mus musculus 94.96 0.00e+00 1769.00
IUUC-Mac-064636 Musa acuminata 60.30 0.00e+00 1090.00
IUUC-Mpu-065961 Mustela putorius furo 94.63 0.00e+00 1766.00
IUUC-Mlu-067059 Myotis lucifugus 95.75 0.00e+00 1705.00
IUUC-Nfi-068277 Neosartorya fischeri 54.78 0.00e+00 936.00
IUUC-Ncr-068659 Neurospora crassa 52.83 0.00e+00 915.00
IUUC-Nle-069034 Nomascus leucogenys 94.96 0.00e+00 1776.00
IUUC-Opr-070334 Ochotona princeps 98.37 0.00e+00 1521.00
IUUC-Ont-071563 Oreochromis niloticus 94.33 0.00e+00 1691.00
IUUC-Oan-073416 Ornithorhynchus anatinus 98.42 0.00e+00 1673.00
IUUC-Ocu-074522 Oryctolagus cuniculus 94.74 0.00e+00 1766.00
IUUC-Oba-075760 Oryza barthii 58.81 0.00e+00 1083.00
IUUC-Obr-076201 Oryza brachyantha 62.04 0.00e+00 1110.00
IUUC-Ogl-077450 Oryza glaberrima 59.98 0.00e+00 1111.00
IUUC-Ogu-078994 Oryza glumaepatula 58.81 0.00e+00 1082.00
IUUC-Oin-079856 Oryza indica 61.06 0.00e+00 1085.00
IUUC-Olo-080731 Oryza longistaminata 58.14 0.00e+00 1066.00
IUUC-Ome-081554 Oryza meridionalis 55.48 0.00e+00 1008.00
IUUC-Oni-082324 Oryza nivara 58.81 0.00e+00 1083.00
IUUC-Opu-083400 Oryza punctata 57.08 0.00e+00 1074.00
IUUC-Oru-084829 Oryza rufipogon 58.81 0.00e+00 1083.00
IUUC-Osa-086026 Oryza sativa 59.98 0.00e+00 1113.00
IUUC-Ola-087245 Oryzias latipes 92.07 0.00e+00 1689.00
IUUC-Olu-087655 Ostreococcus lucimarinus 59.85 0.00e+00 1056.00
IUUC-Oga-088163 Otolemur garnettii 92.24 0.00e+00 1703.00
IUUC-Oar-089842 Ovis aries 95.58 0.00e+00 1761.00
IUUC-Ptr-090501 Pan troglodytes 94.85 0.00e+00 1771.00
IUUC-Pan-092011 Papio anubis 95.07 0.00e+00 1778.00
IUUC-Psi-093308 Pelodiscus sinensis 97.06 0.00e+00 1736.00
IUUC-Pma-094695 Petromyzon marinus 76.89 0.00e+00 1451.00
IUUC-Pno-094785 Phaeosphaeria nodorum 62.41 7.00e-113 401.00
IUUC-Ppa-095911 Physcomitrella patens 61.91 0.00e+00 1135.00
IUUC-Pfo-096587 Poecilia formosa 90.35 0.00e+00 1687.00
IUUC-Pab-097926 Pongo abelii 92.37 0.00e+00 1679.00
IUUC-Pop-099634 Populus trichocarpa 60.42 0.00e+00 1109.00
IUUC-Pca-100965 Procavia capensis 92.86 0.00e+00 1718.00
IUUC-Ppe-101470 Prunus persica 61.35 0.00e+00 1127.00
IUUC-Pva-102451 Pteropus vampyrus 91.88 0.00e+00 1266.00
IUUC-Pgr-103453 Puccinia graminis 54.22 0.00e+00 933.00
IUUC-Ptt-103868 Puccinia triticina 54.92 0.00e+00 931.00
IUUC-Pte-104274 Pyrenophora teres 55.32 0.00e+00 962.00
IUUC-Pyt-104794 Pyrenophora triticirepentis 54.79 0.00e+00 912.00
IUUC-Rno-105979 Rattus norvegicus 84.53 0.00e+00 1265.00
IUUC-Sce-106269 Saccharomyces cerevisiae 47.17 0.00e+00 790.00
IUUC-Sja-107838 Schizosaccharomyces japonicus 47.34 0.00e+00 834.00
IUUC-Spo-108299 Schizosaccharomyces pombe 47.53 0.00e+00 838.00
IUUC-Smo-108695 Selaginella moellendorffii 61.98 0.00e+00 1080.00
IUUC-Sit-110692 Setaria italica 63.32 0.00e+00 1110.00
IUUC-Sly-111775 Solanum lycopersicum 59.84 0.00e+00 1100.00
IUUC-Stu-112906 Solanum tuberosum 60.30 0.00e+00 992.00
IUUC-Sar-113472 Sorex araneus 90.78 0.00e+00 1155.00
IUUC-Sbi-113801 Sorghum bicolor 61.66 0.00e+00 1111.00
IUUC-Sre-115040 Sporisorium reilianum 52.09 0.00e+00 919.00
IUUC-Ssc-115593 Sus scrofa 94.96 0.00e+00 1773.00
IUUC-Tgu-117239 Taeniopygia guttata 96.86 0.00e+00 1751.00
IUUC-Tru-118025 Takifugu rubripes 93.40 0.00e+00 1677.00
IUUC-Tsy-118824 Tarsius syrichta 90.29 0.00e+00 1166.00
IUUC-Tni-120142 Tetraodon nigroviridis 91.33 0.00e+00 1668.00
IUUC-Tca-121613 Theobroma cacao 60.54 0.00e+00 1119.00
IUUC-Tre-122072 Trichoderma reesei 54.99 0.00e+00 934.00
IUUC-Tvi-122546 Trichoderma virens 54.50 0.00e+00 920.00
IUUC-Tae-125488 Triticum aestivum 60.07 0.00e+00 1109.00
IUUC-Tur-126283 Triticum urartu 52.96 0.00e+00 950.00
IUUC-Tme-127041 Tuber melanosporum 56.79 0.00e+00 981.00
IUUC-Tbe-127770 Tupaia belangeri 91.72 0.00e+00 1266.00
IUUC-Ttr-129294 Tursiops truncatus 94.96 0.00e+00 1771.00
IUUC-Uma-129351 Ustilago maydis 51.16 0.00e+00 909.00
IUUC-Vda-129716 Verticillium dahliae 55.61 0.00e+00 958.00
IUUC-Vpa-130037 Vicugna pacos 84.75 0.00e+00 897.00
IUUC-Vvi-131689 Vitis vinifera 61.07 0.00e+00 1121.00
IUUC-Xtr-132633 Xenopus tropicalis 91.75 0.00e+00 1693.00
IUUC-Xma-133347 Xiphophorus maculatus 90.71 0.00e+00 1687.00
IUUC-Yli-134455 Yarrowia lipolytica 50.51 0.00e+00 844.00
IUUC-Zma-135706 Zea mays 61.61 0.00e+00 1129.00
Created Date 25-Jun-2017

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