iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Dme-032105

Ensembl Protein ID

FBpp0310444

UniProt Accession

X2JCI2; X2JCI2_DROME

Genbank Protein ID

AHN57962.1

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AE014296

Gene Name

Src64B; c-src; C-src1; D-src; D-Src64B; Dm SRC1; DmelCG7524; DmHD-358; DSrc; Dsrc; dSrc; dsrc; DSRC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FBgn0262733	FBtr0100505	FBpp0099946
FBgn0262733	FBtr0343995	FBpp0310444

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.10e-14	53.2	97	153

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           k++v +lydy++ ++ +L++ kGd ++vi  ++++ +W++ v+ ++ ++Gl+P nFv++
   Q: 97   KRVVVALYDYKSRDESDLSFMKGDRMEVI--DDTESDWWRVVNLTTRQEGLIPLNFVAE 153
           57899************************..999***********************86 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MGNKCCSKRQ DQELALAYPT GGYKKSDYTF GQTHINSSGG GNMGGVLGQK HNNGGSLDSR 60
YTPDPNHRGP LKIGGKGGVD IIRPRTTPTG VPGVVLKRVV VALYDYKSRD ESDLSFMKGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTCTCTTT CAGAGCATCA CCCATCTCGC TCTAAAATCC ACCGCAGTTT CCCACGATTT 60
TCCTTCTCAC TCTAAAATTC ACCGTTGAAC GACTCGGACG CGATTTTCCA GCGCGGGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000727	Aegilops tauschii	33.84	4.00e-21	96.30
IUUC-Atr-002778	Amborella trichopoda	29.46	2.00e-26	114.00
IUUC-Aly-005712	Arabidopsis lyrata	28.88	6.00e-17	82.40
IUUC-Bdi-014324	Brachypodium distachyon	34.01	9.00e-23	101.00
IUUC-Gma-043938	Glycine max	32.00	1.00e-23	104.00
IUUC-Lpe-051241	Leersia perrieri	35.50	8.00e-23	101.00
IUUC-Oba-074988	Oryza barthii	29.55	3.00e-20	93.20
IUUC-Obr-076676	Oryza brachyantha	36.00	4.00e-23	102.00
IUUC-Ogl-077331	Oryza glaberrima	34.52	6.00e-23	102.00
IUUC-Ogu-078962	Oryza glumaepatula	34.52	6.00e-23	102.00
IUUC-Oin-079172	Oryza indica	34.52	5.00e-23	102.00
IUUC-Olo-080286	Oryza longistaminata	34.52	6.00e-23	102.00
IUUC-Ome-081400	Oryza meridionalis	29.47	4.00e-23	102.00
IUUC-Oni-082734	Oryza nivara	34.52	1.00e-22	100.00
IUUC-Opu-083905	Oryza punctata	29.92	1.00e-20	94.70
IUUC-Oru-084741	Oryza rufipogon	34.52	4.00e-23	102.00
IUUC-Osa-085779	Oryza sativa	34.52	5.00e-23	102.00
IUUC-Pop-099554	Populus trichocarpa	29.07	4.00e-22	99.40
IUUC-Ppe-101646	Prunus persica	34.00	4.00e-24	105.00
IUUC-Smo-109331	Selaginella moellendorffii	32.32	1.00e-21	97.10
IUUC-Sit-110219	Setaria italica	32.58	3.00e-19	89.70
IUUC-Sly-111528	Solanum lycopersicum	33.67	8.00e-23	101.00
IUUC-Stu-112831	Solanum tuberosum	33.17	2.00e-22	100.00
IUUC-Sbi-114480	Sorghum bicolor	32.49	2.00e-22	100.00
IUUC-Tca-121389	Theobroma cacao	29.88	4.00e-23	102.00
IUUC-Tae-123080	Triticum aestivum	34.50	1.00e-21	97.10
IUUC-Tur-126824	Triticum urartu	34.50	1.00e-21	97.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence