iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118254

UUCD1 version

UUC-TaR-00292

Ensembl Protein ID

ENSTRUP00000014807.1

UniProt Accession

H2SQX0; H2SQX0_TAKRU

Protein Name

Uncharacterized protein

Gene Name

tbl1xr1b; LOC101066969

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000006095.1	ENSTRUT00000014875.1	ENSTRUP00000014807.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-52	174.7	450	488
UBD/Beta-Prp	9.90e-78	262.6	237	522

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+++v+++af +d ++l+sGs D+ +++W++ tg l++s
   Q: 450  HQEPVYSVAFsPDgRHLASGSFDKCVHIWNTQTGALVHS 488
           9**********999*******************998875 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsls 101
           +t++++  +++llatgs+dg  ++w   +g+l ++l +h++++ a+k++++g+++++++ D+t  +wd  tg+  + +  h++ +l+++
   Q: 237  VTSLDWNSEGTLLATGSYDGFARIWTK-DGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVD 324
           67799999*****************75.56999******************************************************** PP
   S: 102  fspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfds 190
           ++  +++++s s d  i+v +l ++  ++ t++gh+  vn ++++p+g+ll+s+s+D t+++W++k+++++++l+  h + +y +++++
   Q: 325  WQS-NNTFASCSTDMCIHVCKLGQDRPVK-TFQGHTNEVNAIKWDPTGSLLASCSDDMTLKIWSMKQDTCVHDLQA-HSKEIYTIKWSP 410
           *99.99***********************.*********************************************8.************ PP
   S: 191  ng.........kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisv 270
           +g           l+s+s d+tv+lwd+++g c++tl++h+++v+sv+fsp++ +l+sgs D+ + iW++++g l++++ ++    i  
   Q: 411  TGpgtnnpsasLMLASASFDSTVRLWDVERGVCIHTLTCHQEPVYSVAFSPDGRHLASGSFDKCVHIWNTQTGALVHSYRGTG--GIFE 497
           *********9999******************************************************************9965..3333 PP
   S: 271  avlsfgdnvlvlgsedskvniwklk 295
            +++ ++ ++ + ++d++v +++l+
   Q: 498  VCWNATGDKVGASASDGSVCVLDLR 522
           3445555555555566788777776 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MSISSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GALVPPAALI SIIQKGLQYV 60
EAEVSINEDG TLFDGRPIES LSLIDAVMPD VVQTRQQAYR DKLAQQQQQQ QQQQATGSSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCATAA GCAGCGATGA GGTCAACTTC CTGGTTTATA GGTACCTGCA GGAGTCGGGT 60
ATGTCAGCGT TCTGCTGCAG TTCCAGTCAT CCGGTAGAAG TGTATTCCCG CTGTGCTGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0003714--F:transcription corepressor activity
GO:0016575--P:histone deacetylation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

KEGG

tru:101066969

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002514	Amborella trichopoda	65.66	2.00e-144	505.00
IUUC-Aly-005622	Arabidopsis lyrata	58.33	5.00e-121	428.00
IUUC-Ath-007137	Arabidopsis thaliana	59.41	1.00e-122	433.00
IUUC-Ame-011601	Astyanax mexicanus	90.82	0.00e+00	912.00
IUUC-Bdi-014315	Brachypodium distachyon	60.69	2.00e-134	472.00
IUUC-Bol-016277	Brassica oleracea	57.03	1.00e-126	446.00
IUUC-Bra-016944	Brassica rapa	60.28	1.00e-125	443.00
IUUC-Cne-026946	Cryptococcus neoformans	38.01	5.00e-31	129.00
IUUC-Dre-027906	Danio rerio	90.82	0.00e+00	917.00
IUUC-Dme-031939	Drosophila melanogaster	81.42	6.00e-175	607.00
IUUC-Gmo-038870	Gadus morhua	91.20	0.00e+00	945.00
IUUC-Gac-041770	Gasterosteus aculeatus	93.12	0.00e+00	987.00
IUUC-Gma-043369	Glycine max	62.09	7.00e-136	477.00
IUUC-Lpe-051084	Leersia perrieri	63.19	5.00e-137	481.00
IUUC-Mtr-058624	Medicago truncatula	60.71	2.00e-128	452.00
IUUC-Mvi-060557	Microbotryum violaceum	36.51	3.00e-69	256.00
IUUC-Ont-071569	Oreochromis niloticus	94.65	0.00e+00	971.00
IUUC-Oba-075618	Oryza barthii	48.83	1.00e-142	499.00
IUUC-Obr-076718	Oryza brachyantha	61.03	1.00e-137	483.00
IUUC-Ogl-077302	Oryza glaberrima	50.81	4.00e-157	547.00
IUUC-Ogu-078718	Oryza glumaepatula	50.81	4.00e-157	547.00
IUUC-Oin-079515	Oryza indica	44.34	1.00e-95	344.00
IUUC-Olo-080427	Oryza longistaminata	63.90	2.00e-132	466.00
IUUC-Ome-081696	Oryza meridionalis	49.73	6.00e-152	530.00
IUUC-Oni-082137	Oryza nivara	50.81	4.00e-157	547.00
IUUC-Oru-085276	Oryza rufipogon	50.63	1.00e-156	546.00
IUUC-Osa-085791	Oryza sativa	50.81	4.00e-157	547.00
IUUC-Ppa-095868	Physcomitrella patens	65.16	2.00e-139	489.00
IUUC-Pop-098989	Populus trichocarpa	62.09	7.00e-129	453.00
IUUC-Sit-110710	Setaria italica	64.27	7.00e-143	500.00
IUUC-Sbi-114420	Sorghum bicolor	63.74	6.00e-143	501.00
IUUC-Tni-120861	Tetraodon nigroviridis	94.08	0.00e+00	969.00
IUUC-Tca-121739	Theobroma cacao	57.14	6.00e-125	441.00
IUUC-Tme-127126	Tuber melanosporum	37.65	4.00e-58	218.00
IUUC-Vvi-131193	Vitis vinifera	59.89	4.00e-128	451.00
IUUC-Xma-134168	Xiphophorus maculatus	92.37	0.00e+00	980.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence