iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Rno-105607

Ensembl Protein ID

ENSRNOP00000066399.1

UniProt Accession

M0RA58; M0RA58_RAT

Genbank Protein ID

ENSRNOP00000066399

Protein Name

Deltex E3 ubiquitin ligase 1

Genbank Nucleotide ID

AABR07036386

Gene Name

Dtx1; LOC687424

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000050848.1	ENSRNOT00000074974.1	ENSRNOP00000066399.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.90e-08	34.5	418	479

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..............kdgpl......vlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC+e++                  +      +++CgH++h+ Cl ++ +++ ++ ++ +CP+C+
   Q: 418  CTICMERLvtasgyegvlrnksV---RpelvgrLGRCGHMYHLLCLVAM-YSNGNKDGSLQCPTCK 479
           9*******888876666654331...1333333799**********666.79999**********6 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSRPGQGVMV PVNGLGFPPQ NVARVVVWEW LNEHSRWRPY TATVCHHIEN VLKEDARGSV 60
VLGQVDAQLV PYIIDLQSMH QFRQDTGTMR PVRRNFYDPS SAPGKGIVWE WENDGGAWTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCACGGC CAGGCCAAGG TGTGATGGTG CCGGTGAACG GGCTGGGCTT CCCGCCGCAG 60
AACGTAGCCC GGGTGGTGGT GTGGGAGTGG CTCAACGAGC ACAGCCGCTG GCGACCCTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50918--WWE
PS50089--ZF_RING_2

Pfam

PF02825--WWE
PF00097--zf-C3HC4

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0008270--F:zinc ion binding
GO:0010001--P:glial cell differentiation
GO:0045665--P:negative regulation of neuron differentiation
GO:0045581--P:negative regulation of T cell differentiation
GO:0007219--P:Notch signaling pathway
GO:0008593--P:regulation of Notch signaling pathway

KEGG

rno:687424

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000830	Aegilops tauschii	31.25	6.00e-05	42.00
IUUC-Aml-001735	Ailuropoda melanoleuca	99.00	1.00e-158	553.00
IUUC-Aca-005007	Anolis carolinensis	79.87	0.00e+00	991.00
IUUC-Ame-011497	Astyanax mexicanus	73.74	0.00e+00	887.00
IUUC-Bta-012612	Bos taurus	95.22	0.00e+00	1039.00
IUUC-Bdi-014427	Brachypodium distachyon	28.12	2.00e-04	40.00
IUUC-Bra-017349	Brassica rapa	35.94	8.00e-05	40.80
IUUC-Cja-019328	Callithrix jacchus	98.69	4.00e-160	558.00
IUUC-Csa-023525	Chlorocebus sabaeus	95.37	0.00e+00	1027.00
IUUC-Dre-028108	Danio rerio	82.62	3.00e-147	514.00
IUUC-Eca-033826	Equus caballus	90.46	9.00e-155	540.00
IUUC-Fca-036290	Felis catus	92.73	2.00e-155	542.00
IUUC-Gmo-039078	Gadus morhua	81.60	2.00e-156	545.00
IUUC-Gac-042521	Gasterosteus aculeatus	74.40	0.00e+00	868.00
IUUC-Ggo-044598	Gorilla gorilla	83.78	0.00e+00	973.00
IUUC-Hsa-046570	Homo sapiens	95.06	0.00e+00	1028.00
IUUC-Hvu-047201	Hordeum vulgare	31.25	7.00e-05	42.00
IUUC-Itr-049005	Ictidomys tridecemlineatus	96.85	2.00e-162	565.00
IUUC-Lch-050642	Latimeria chalumnae	82.85	4.00e-147	513.00
IUUC-Loc-052134	Lepisosteus oculatus	76.04	0.00e+00	937.00
IUUC-Laf-054360	Loxodonta africana	98.49	4.00e-174	604.00
IUUC-Meu-056430	Macropus eugenii	92.46	5.00e-164	570.00
IUUC-Mmr-061378	Microcebus murinus	87.54	2.00e-148	519.00
IUUC-Mmu-064234	Mus musculus	99.68	0.00e+00	1064.00
IUUC-Mpu-066343	Mustela putorius furo	98.06	2.00e-161	561.00
IUUC-Mlu-067905	Myotis lucifugus	93.64	2.00e-162	565.00
IUUC-Nle-069498	Nomascus leucogenys	93.30	0.00e+00	991.00
IUUC-Opr-070885	Ochotona princeps	89.65	0.00e+00	927.00
IUUC-Oan-073617	Ornithorhynchus anatinus	78.60	0.00e+00	676.00
IUUC-Oba-075224	Oryza barthii	27.27	1.00e-05	44.30
IUUC-Ogl-077568	Oryza glaberrima	27.27	1.00e-05	44.70
IUUC-Ogu-077958	Oryza glumaepatula	27.27	1.00e-05	44.30
IUUC-Oin-079699	Oryza indica	27.27	1.00e-05	44.70
IUUC-Ome-081380	Oryza meridionalis	27.27	1.00e-05	44.30
IUUC-Oni-082776	Oryza nivara	27.27	1.00e-05	44.70
IUUC-Opu-083671	Oryza punctata	26.36	8.00e-06	45.10
IUUC-Oru-085146	Oryza rufipogon	27.27	1.00e-05	44.70
IUUC-Osa-085571	Oryza sativa	27.27	1.00e-05	44.70
IUUC-Oga-088768	Otolemur garnettii	95.38	0.00e+00	1021.00
IUUC-Ptr-090522	Pan troglodytes	91.39	0.00e+00	968.00
IUUC-Pan-092352	Papio anubis	95.06	0.00e+00	1027.00
IUUC-Psi-093534	Pelodiscus sinensis	87.32	2.00e-145	508.00
IUUC-Pma-094460	Petromyzon marinus	74.75	6.00e-134	469.00
IUUC-Pab-098315	Pongo abelii	91.07	0.00e+00	957.00
IUUC-Pca-100459	Procavia capensis	97.52	9.00e-108	384.00
IUUC-Pva-102574	Pteropus vampyrus	87.11	2.00e-174	605.00
IUUC-Pte-104269	Pyrenophora teres	30.86	6.00e-04	37.40
IUUC-Sha-107129	Sarcophilus harrisii	81.97	0.00e+00	1009.00
IUUC-Sit-110693	Setaria italica	23.64	2.00e-05	43.90
IUUC-Ssc-116198	Sus scrofa	93.37	9.00e-163	566.00
IUUC-Tru-118569	Takifugu rubripes	73.93	0.00e+00	919.00
IUUC-Tae-125355	Triticum aestivum	24.55	1.00e-05	44.70
IUUC-Ttr-128583	Tursiops truncatus	93.30	0.00e+00	1010.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence