iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-058254

Ensembl Protein ID

AES78077

UniProt Accession

G7KWT8; G7KWT8_MEDTR

Genbank Protein ID

AES78077.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

CM001223

Gene Name

MTR_7g024290

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_7g024290	AES78077	AES78077

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_PIM	1.50e-16	61.5	241	313

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesg.vppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvk 72
           m++ v+t +gk +++ v+++dt+ ++Keki ++ + +++  q+LI+a k+L D+ t+ +++i++ s++hlv +
   Q: 241  MQIYVMTQTGKVIPIGVKSSDTIGNVKEKIFDKNKdYQVHVQRLIFASKQLDDSLTIANCNIQERSTLHLVSR 313
           89****************************777666**********************************976 PP

Organism

Medicago truncatula

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MEPLTISNSK LLDCCNCFQP LSIPVFQCDN GHIVCSTCCP KLRNKCHKCS LHISSKRCIA 60
IENLLQSIEM SCLNAKHGCK EKISYTGNRK HEEECIYVPC YCPLSGCDFV ASSEVLSNHF 120

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Nucleotide Sequence
(Fasta)

CAAAAATCAA CACATCAAAC CACCAACGAT TCTACAATTT CTCAGTGAGT ATTTTGTTAA 60
ATGTTATTTT CAACAGCTTA ATTTGACTAG TTTAACTTGT TATTTTTTTA GCCATAAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR019956--Ubiquitin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50053--UBIQUITIN_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina
PF00240--ubiquitin

PRINTS

PR00348--UBIQUITIN

SMART

SM00213--UBQ

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mtr:MTR_7g024290

Orthology

iUUCD ID

Species

Identity

E-value

Score

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence