iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060016

UUCD1 version

UUC-MeG-00867

Ensembl Protein ID

ENSMGAP00000010201.1

UniProt Accession

G1NBZ4; G1NBZ4_MELGA

Protein Name

Uncharacterized protein

Gene Name

USP14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000009838.1	ENSMGAT00000011047.1	ENSMGAP00000010201.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.60e-63	212.4	105	478
ULD/UDP/UBQ/UBQ_Other	1.40e-08	34.2	6	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.... 85
           +Gl+NlgNtCYmN+++Qc+ ++pe++e+l++ +  +l+++ +  + + ++ +l++lf ++ +++++++ p  ll+ l+++ ++f     
   Q: 105  CGLTNLGNTCYMNATVQCIRSVPEVKEALKR-YGGALRASGEMASAQYITAALRDLFDSM-DKTSSSIPPIILLQFLHMAFPQFAekgd 191
           7******************************.****************************.99999******************99*** PP
   S: 86   ..gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
             +y qqDa+E++ +++  l+++l+           e d+   +d+    + +k+ksli++ F +++++ +kc e +++ +++ + ++l
   Q: 192  qgQYLQQDANECWVQMMRVLQQKLEG---------IEGDTVMETDSGTTATASKKKSLIDQFFSIEFETAMKCTEAEEEEVTKGKENQL 271
           999*********************55.........4444445556677999***************************99999888888 PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +l+   ++e   + l   L+   +ee  +      +++ +++    k+ k+++lP +L++++ Rf ++e+++++ k+ k v+fpl+Ld+
   Q: 272  QLSCFINQEV--KYLFTGLKLRLQEEITK-----LSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDV 353
           8888877754..58999999999998887.....7899999999********************************************* PP
   S: 262  spfcts........................peekqke...........................kkkYeLiavvvHsG.slssGHYvay 298
            + ct                         p     +                           +  Y+L av+ H+G s+ssGHYv++
   Q: 354  YELCTPdlqekmvsyrskfkdledkkvnqqP-----KnlnksdgaqkevkyepfsfpddigsnnCGYYDLQAVLTHQGrSSSSGHYVSW 437
           ******7777777777777666665555550.....0555555666666666666666677666************************* PP
   S: 299  vknekgkWllfdDskVtevkeeevleetg....staYvlfY 335
           vk ++++W++fdD+kV+ v+ e++l+ +g    + aYvl+Y
   Q: 438  VKRKQDEWIKFDDDKVSIVTPEDILRLSGggdwHIAYVLLY 478
           **************************988************ PP

ULD/UDP/UBQ/UBQ_Other

   S: 3    vtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllek 72
           v vk+ + +  ++++n +++  ++K +++ ++g++p++q+ ++kG  L+dd ++++ ++k+g+t++++ +
   Q: 6    VNVKWGKEKFDGVELNTDEPPMVFKAQLFALTGVQPARQKVMLKGGTLKDD-DWGNIKIKNGMTLLMMGS 74
           6799999998899***********************************999.9**************965 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

ILLFAVNVKW GKEKFDGVEL NTDEPPMVFK AQLFALTGVQ PARQKVMLKG GTLKDDDWGN 60
IKIKNGMTLL MMGSADALPE EPIARPVFVE DMTEEQLASA MELPCGLTNL GNTCYMNATV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATACTTTTGT TTGCAGTTAA TGTGAAATGG GGTAAAGAGA AATTTGATGG TGTGGAGCTG 60
AACACGGATG AGCCTCCAAT GGTCTTCAAG GCTCAGCTGT TTGCCCTGAC CGGAGTTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00299--UBIQUITIN_1
PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0009986--C:cell surface
GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0045202--C:synapse
GO:0004866--F:endopeptidase inhibitor activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007268--P:chemical synaptic transmission
GO:1903070--P:negative regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0050920--P:regulation of chemotaxis
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	43.41	4.00e-38	152.00
IUUC-Aml-002053	Ailuropoda melanoleuca	89.88	0.00e+00	881.00
IUUC-Atr-002725	Amborella trichopoda	41.28	2.00e-100	358.00
IUUC-Apl-004031	Anas platyrhynchos	98.58	0.00e+00	965.00
IUUC-Aca-004361	Anolis carolinensis	92.70	0.00e+00	946.00
IUUC-Aly-006176	Arabidopsis lyrata	41.21	3.00e-110	391.00
IUUC-Ath-007658	Arabidopsis thaliana	40.84	6.00e-110	390.00
IUUC-Ago-007796	Ashbya gossypii	32.35	2.00e-57	216.00
IUUC-Acl-008258	Aspergillus clavatus	37.21	3.00e-64	238.00
IUUC-Afl-008732	Aspergillus flavus	34.22	8.00e-80	290.00
IUUC-Afu-008755	Aspergillus fumigatus	34.72	3.00e-79	288.00
IUUC-Ani-009148	Aspergillus nidulans	39.36	5.00e-70	258.00
IUUC-Ang-009878	Aspergillus niger	37.76	1.00e-63	236.00
IUUC-Aor-010239	Aspergillus oryzae	34.22	8.00e-80	290.00
IUUC-Ate-010243	Aspergillus terreus	34.72	3.00e-78	285.00
IUUC-Ame-011327	Astyanax mexicanus	51.51	6.00e-126	443.00
IUUC-Bgr-012231	Blumeria graminis	37.63	5.00e-65	241.00
IUUC-Bta-012553	Bos taurus	90.45	0.00e+00	890.00
IUUC-Bci-013606	Botrytis cinerea	39.58	2.00e-69	256.00
IUUC-Bdi-014567	Brachypodium distachyon	42.83	8.00e-112	396.00
IUUC-Bol-016127	Brassica oleracea	40.56	9.00e-110	390.00
IUUC-Bra-017297	Brassica rapa	41.32	2.00e-111	395.00
IUUC-Cel-018140	Caenorhabditis elegans	42.24	3.00e-102	365.00
IUUC-Cja-019516	Callithrix jacchus	89.88	0.00e+00	892.00
IUUC-Cfa-020808	Canis familiaris	90.85	0.00e+00	898.00
IUUC-Cpo-021688	Cavia porcellus	90.30	0.00e+00	892.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	39.02	2.00e-85	308.00
IUUC-Csa-023429	Chlorocebus sabaeus	90.63	0.00e+00	874.00
IUUC-Cho-024347	Choloepus hoffmanni	90.63	0.00e+00	892.00
IUUC-Cin-025198	Ciona intestinalis	54.40	2.00e-152	532.00
IUUC-Csv-026007	Ciona savignyi	53.24	6.00e-152	530.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	39.02	2.00e-62	233.00
IUUC-Cne-026963	Cryptococcus neoformans	34.95	7.00e-75	274.00
IUUC-Cme-027240	Cyanidioschyzon merolae	30.74	4.00e-59	221.00
IUUC-Dre-027647	Danio rerio	83.78	0.00e+00	847.00
IUUC-Dno-029967	Dasypus novemcinctus	89.23	0.00e+00	875.00
IUUC-Dor-030886	Dipodomys ordii	85.00	0.00e+00	722.00
IUUC-Dse-031466	Dothistroma septosporum	36.02	3.00e-57	216.00
IUUC-Dme-032079	Drosophila melanogaster	54.89	4.00e-156	543.00
IUUC-Ete-032351	Echinops telfairi	81.63	0.00e+00	816.00
IUUC-Eca-033461	Equus caballus	89.68	0.00e+00	933.00
IUUC-Eeu-035220	Erinaceus europaeus	69.14	0.00e+00	644.00
IUUC-Fca-036210	Felis catus	91.06	0.00e+00	899.00
IUUC-Fal-037528	Ficedula albicollis	97.54	0.00e+00	934.00
IUUC-Fox-037805	Fusarium oxysporum	40.21	7.00e-70	257.00
IUUC-Fso-038177	Fusarium solani	38.24	3.00e-66	245.00
IUUC-Gmo-038953	Gadus morhua	78.69	0.00e+00	767.00
IUUC-Ggr-039972	Gaeumannomyces graminis	34.51	3.00e-74	272.00
IUUC-Gga-040462	Gallus gallus	97.76	0.00e+00	955.00
IUUC-Gac-041312	Gasterosteus aculeatus	80.12	0.00e+00	808.00
IUUC-Gma-043255	Glycine max	41.60	1.00e-106	379.00
IUUC-Ggo-045458	Gorilla gorilla	75.45	0.00e+00	738.00
IUUC-Hsa-045706	Homo sapiens	90.85	0.00e+00	878.00
IUUC-Hvu-047821	Hordeum vulgare	46.73	6.00e-57	213.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	88.41	0.00e+00	898.00
IUUC-Lch-050464	Latimeria chalumnae	83.88	0.00e+00	842.00
IUUC-Lpe-051419	Leersia perrieri	41.67	5.00e-107	380.00
IUUC-Loc-052732	Lepisosteus oculatus	82.82	0.00e+00	855.00
IUUC-Lma-053177	Leptosphaeria maculans	41.51	2.00e-69	256.00
IUUC-Laf-053822	Loxodonta africana	90.87	0.00e+00	896.00
IUUC-Mcc-055893	Macaca mulatta	90.84	0.00e+00	876.00
IUUC-Meu-056307	Macropus eugenii	80.61	0.00e+00	790.00
IUUC-Mor-057171	Magnaporthe oryzae	39.84	3.00e-66	245.00
IUUC-Mpo-057415	Magnaporthe poae	40.85	1.00e-69	256.00
IUUC-Mtr-057901	Medicago truncatula	42.48	1.00e-109	389.00
IUUC-Mla-058897	Melampsora laricipopulina	39.84	2.00e-75	275.00
IUUC-Mvi-060562	Microbotryum violaceum	39.44	8.00e-67	247.00
IUUC-Mmr-060624	Microcebus murinus	90.24	0.00e+00	931.00
IUUC-Mdo-061809	Monodelphis domestica	92.31	0.00e+00	901.00
IUUC-Mmu-063869	Mus musculus	89.43	0.00e+00	882.00
IUUC-Mac-064876	Musa acuminata	38.74	8.00e-95	340.00
IUUC-Mpu-066480	Mustela putorius furo	90.45	0.00e+00	894.00
IUUC-Mlu-067866	Myotis lucifugus	89.27	0.00e+00	900.00
IUUC-Nfi-068393	Neosartorya fischeri	37.35	3.00e-65	242.00
IUUC-Ncr-068815	Neurospora crassa	40.00	1.00e-68	253.00
IUUC-Nle-070121	Nomascus leucogenys	90.04	3.00e-129	453.00
IUUC-Opr-070712	Ochotona princeps	72.66	2.00e-164	572.00
IUUC-Ont-071544	Oreochromis niloticus	81.97	0.00e+00	771.00
IUUC-Oan-073635	Ornithorhynchus anatinus	92.27	0.00e+00	764.00
IUUC-Ocu-074926	Oryctolagus cuniculus	89.82	0.00e+00	871.00
IUUC-Oba-075633	Oryza barthii	41.67	1.00e-106	379.00
IUUC-Obr-076423	Oryza brachyantha	41.72	3.00e-109	388.00
IUUC-Ogl-077913	Oryza glaberrima	41.67	2.00e-109	389.00
IUUC-Ogu-078435	Oryza glumaepatula	41.67	1.00e-106	379.00
IUUC-Oin-080072	Oryza indica	41.91	9.00e-107	380.00
IUUC-Olo-080535	Oryza longistaminata	38.13	3.00e-91	328.00
IUUC-Ome-081309	Oryza meridionalis	41.67	1.00e-106	379.00
IUUC-Oni-083113	Oryza nivara	41.67	1.00e-106	379.00
IUUC-Opu-083168	Oryza punctata	40.71	5.00e-101	360.00
IUUC-Oru-084253	Oryza rufipogon	41.67	1.00e-106	379.00
IUUC-Osa-085554	Oryza sativa	41.67	8.00e-110	390.00
IUUC-Ola-086998	Oryzias latipes	80.61	0.00e+00	797.00
IUUC-Olu-087818	Ostreococcus lucimarinus	36.97	4.00e-71	261.00
IUUC-Oga-088571	Otolemur garnettii	90.63	0.00e+00	894.00
IUUC-Oar-089526	Ovis aries	91.06	0.00e+00	895.00
IUUC-Ptr-091433	Pan troglodytes	90.84	0.00e+00	876.00
IUUC-Pan-091966	Papio anubis	90.63	0.00e+00	874.00
IUUC-Psi-093458	Pelodiscus sinensis	93.07	0.00e+00	889.00
IUUC-Pma-094343	Petromyzon marinus	68.73	2.00e-120	424.00
IUUC-Pno-095109	Phaeosphaeria nodorum	39.79	1.00e-64	240.00
IUUC-Ppa-095756	Physcomitrella patens	41.98	1.00e-109	389.00
IUUC-Pfo-096514	Poecilia formosa	82.99	0.00e+00	793.00
IUUC-Pab-098477	Pongo abelii	79.79	0.00e+00	699.00
IUUC-Pop-099221	Populus trichocarpa	41.12	4.00e-104	371.00
IUUC-Pca-100791	Procavia capensis	74.36	2.00e-166	577.00
IUUC-Ppe-101812	Prunus persica	41.21	4.00e-107	380.00
IUUC-Pva-102462	Pteropus vampyrus	85.55	0.00e+00	721.00
IUUC-Pgr-103623	Puccinia graminis	41.50	8.00e-77	280.00
IUUC-Ptt-103767	Puccinia triticina	39.64	7.00e-68	251.00
IUUC-Pte-104109	Pyrenophora teres	39.84	7.00e-70	257.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	40.48	2.00e-70	259.00
IUUC-Rno-105351	Rattus norvegicus	88.41	0.00e+00	852.00
IUUC-Sce-106168	Saccharomyces cerevisiae	31.98	3.00e-61	229.00
IUUC-Sha-107491	Sarcophilus harrisii	92.29	0.00e+00	916.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	34.99	6.00e-80	291.00
IUUC-Spo-108174	Schizosaccharomyces pombe	36.40	7.00e-79	287.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	34.86	6.00e-82	298.00
IUUC-Smo-109276	Selaginella moellendorffii	43.12	2.00e-108	385.00
IUUC-Sit-110361	Setaria italica	42.80	4.00e-113	401.00
IUUC-Sly-110965	Solanum lycopersicum	41.08	4.00e-108	384.00
IUUC-Sar-113355	Sorex araneus	79.16	0.00e+00	636.00
IUUC-Sbi-114778	Sorghum bicolor	43.35	2.00e-111	395.00
IUUC-Sre-115011	Sporisorium reilianum	36.64	6.00e-63	234.00
IUUC-Ssc-116273	Sus scrofa	90.63	0.00e+00	884.00
IUUC-Tgu-117063	Taeniopygia guttata	97.14	0.00e+00	935.00
IUUC-Tru-118381	Takifugu rubripes	80.86	0.00e+00	805.00
IUUC-Tsy-119076	Tarsius syrichta	75.49	7.00e-111	393.00
IUUC-Tni-119941	Tetraodon nigroviridis	81.52	0.00e+00	791.00
IUUC-Tca-121246	Theobroma cacao	41.88	3.00e-108	384.00
IUUC-Tre-121969	Trichoderma reesei	37.37	1.00e-63	237.00
IUUC-Tvi-122543	Trichoderma virens	32.56	7.00e-66	244.00
IUUC-Tae-125484	Triticum aestivum	42.54	9.00e-109	386.00
IUUC-Tur-126128	Triticum urartu	31.75	1.00e-66	246.00
IUUC-Tbe-128030	Tupaia belangeri	83.81	0.00e+00	799.00
IUUC-Ttr-128701	Tursiops truncatus	89.62	0.00e+00	732.00
IUUC-Uma-129657	Ustilago maydis	37.01	2.00e-65	242.00
IUUC-Vda-129723	Verticillium dahliae	36.59	7.00e-59	221.00
IUUC-Vpa-130284	Vicugna pacos	64.14	2.00e-168	584.00
IUUC-Vvi-131037	Vitis vinifera	43.12	2.00e-109	388.00
IUUC-Xtr-132235	Xenopus tropicalis	86.79	0.00e+00	895.00
IUUC-Xma-133840	Xiphophorus maculatus	82.99	0.00e+00	817.00
IUUC-Yli-134453	Yarrowia lipolytica	36.33	1.00e-81	296.00
IUUC-Zma-135669	Zea mays	36.04	9.00e-94	337.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence