iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098760

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01364127

Gene Name

UBE2D4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000029727.1	ENSPPYT00000033354.1	ENSPPYP00000024091.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.30e-57	191.8	5	139
UBD/UBC-like/UBD_UBC	1.70e-83	277.7	5	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++l++dpp+++sa+pv + dl++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+tki+hPn+++nG++Cl+il+  
   Q: 5    RIQKELTDLQRDPPAQCSAGPVGD-DLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILR-- 90
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wspal+v++vllsi+sll++pnp++pl  e+a+++k++re+y++ +r
   Q: 91   SQWSPALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADREKYNRLAR 139
           *********************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqw 89
           ri+kel dl+rd++aq+sa++v+ddlf+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+tkiyhpninsngsicldilrsqw
   Q: 5    RIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQW 93
           8**************************************************************************************** PP
   S: 90   saaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           s+alt+skvlls+csll+d++pddplv+eia+ yk+d+eky+r arewt
   Q: 94   SPALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADREKYNRLAREWT 142
           ************************************************8 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MALKRIQKEL TDLQRDPPAQ CSAGPVGDDL FHWQATIMGP NDSPYQGGVF FLTIHFPTDY 60
PFKPPKVAFT TKIYHPNINS NGSICLDILR SQWSPALTVS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCAGTTTGA AGAACTCTAA CCTAGACGTC TGCCAAGTCT TGGGAAAATA GGAAGGAGAC 60
AGATAATTAA GTTTGGGAAA TGCATAGTCT AAGGCCTTGG TTCTCAACGT TGGCAGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008266	Aspergillus clavatus	85.71	1.00e-74	271.00
IUUC-Afl-008709	Aspergillus flavus	80.28	1.00e-69	257.00
IUUC-Afu-008956	Aspergillus fumigatus	86.39	5.00e-75	272.00
IUUC-Ani-009401	Aspergillus nidulans	84.35	1.00e-73	267.00
IUUC-Ang-009725	Aspergillus niger	84.80	1.00e-62	231.00
IUUC-Ate-010438	Aspergillus terreus	85.03	7.00e-74	268.00
IUUC-Ame-011566	Astyanax mexicanus	95.24	1.00e-82	297.00
IUUC-Bci-013661	Botrytis cinerea	84.35	1.00e-74	271.00
IUUC-Bdi-014561	Brachypodium distachyon	80.27	2.00e-71	260.00
IUUC-Bol-015722	Brassica oleracea	81.63	8.00e-72	262.00
IUUC-Bra-016748	Brassica rapa	78.91	2.00e-70	260.00
IUUC-Cja-019014	Callithrix jacchus	96.48	3.00e-81	293.00
IUUC-Cpo-021897	Cavia porcellus	97.20	9.00e-82	295.00
IUUC-Cre-022765	Chlamydomonas reinhardtii	79.59	3.00e-70	256.00
IUUC-Csa-023377	Chlorocebus sabaeus	97.60	6.00e-96	342.00
IUUC-Cin-025379	Ciona intestinalis	88.36	2.00e-76	277.00
IUUC-Cgl-026490	Colletotrichum gloeosporioides	85.03	2.00e-74	270.00
IUUC-Cne-026957	Cryptococcus neoformans	80.82	2.00e-70	256.00
IUUC-Cme-027220	Cyanidioschyzon merolae	82.99	5.00e-72	262.00
IUUC-Dre-028686	Danio rerio	98.64	3.00e-85	306.00
IUUC-Dor-030323	Dipodomys ordii	98.64	3.00e-85	306.00
IUUC-Dse-031397	Dothistroma septosporum	85.03	1.00e-74	271.00
IUUC-Eca-033231	Equus caballus	99.28	9.00e-81	291.00
IUUC-Fox-038021	Fusarium oxysporum	85.03	4.00e-74	269.00
IUUC-Fso-038297	Fusarium solani	84.35	7.00e-74	268.00
IUUC-Gmo-038775	Gadus morhua	91.84	1.00e-80	291.00
IUUC-Gma-043733	Glycine max	80.41	2.00e-71	260.00
IUUC-Ggo-045361	Gorilla gorilla	99.32	1.00e-85	307.00
IUUC-Hsa-045934	Homo sapiens	99.32	1.00e-85	307.00
IUUC-Hvu-047546	Hordeum vulgare	77.55	4.00e-69	253.00
IUUC-Kpa-049290	Komagataella pastoris	78.91	8.00e-70	255.00
IUUC-Lch-050109	Latimeria chalumnae	87.07	3.00e-77	280.00
IUUC-Lpe-051289	Leersia perrieri	80.95	8.00e-71	258.00
IUUC-Loc-052838	Lepisosteus oculatus	99.32	1.00e-85	307.00
IUUC-Lma-053121	Leptosphaeria maculans	85.03	7.00e-75	271.00
IUUC-Mcc-055421	Macaca mulatta	99.32	1.00e-85	307.00
IUUC-Mor-057235	Magnaporthe oryzae	84.35	1.00e-73	268.00
IUUC-Nfi-068599	Neosartorya fischeri	86.39	5.00e-75	272.00
IUUC-Nle-069715	Nomascus leucogenys	99.32	1.00e-85	307.00
IUUC-Ont-072562	Oreochromis niloticus	95.92	2.00e-83	300.00
IUUC-Oan-073026	Ornithorhynchus anatinus	98.57	6.00e-81	292.00
IUUC-Oba-075411	Oryza barthii	80.95	8.00e-71	258.00
IUUC-Ogl-076968	Oryza glaberrima	80.95	2.00e-71	260.00
IUUC-Ogu-078091	Oryza glumaepatula	80.69	8.00e-71	260.00
IUUC-Oin-079659	Oryza indica	80.95	2.00e-71	260.00
IUUC-Olo-080786	Oryza longistaminata	80.95	8.00e-71	258.00
IUUC-Ome-081987	Oryza meridionalis	78.91	6.00e-70	255.00
IUUC-Oni-082391	Oryza nivara	80.95	1.00e-71	263.00
IUUC-Oru-085167	Oryza rufipogon	80.95	1.00e-71	263.00
IUUC-Osa-086003	Oryza sativa	80.95	2.00e-71	260.00
IUUC-Ola-087515	Oryzias latipes	96.60	1.00e-83	301.00
IUUC-Olu-087615	Ostreococcus lucimarinus	77.55	5.00e-67	245.00
IUUC-Pan-092614	Papio anubis	96.55	5.00e-82	295.00
IUUC-Pno-094765	Phaeosphaeria nodorum	85.03	7.00e-75	271.00
IUUC-Ppa-095177	Physcomitrella patens	80.27	2.00e-70	257.00
IUUC-Pfo-096867	Poecilia formosa	96.60	1.00e-83	301.00
IUUC-Pop-099853	Populus trichocarpa	80.27	2.00e-70	257.00
IUUC-Ppe-101431	Prunus persica	80.95	6.00e-71	259.00
IUUC-Pte-104015	Pyrenophora teres	85.03	1.00e-74	271.00
IUUC-Pyt-104701	Pyrenophora triticirepentis	85.03	1.00e-74	271.00
IUUC-Sce-106463	Saccharomyces cerevisiae	81.25	6.00e-71	258.00
IUUC-Sja-107729	Schizosaccharomyces japonicus	84.35	2.00e-73	267.00
IUUC-Spo-108032	Schizosaccharomyces pombe	84.35	2.00e-73	267.00
IUUC-Ssl-108443	Sclerotinia sclerotiorum	85.03	5.00e-75	272.00
IUUC-Smo-109317	Selaginella moellendorffii	80.27	4.00e-70	256.00
IUUC-Sit-109936	Setaria italica	80.95	2.00e-71	261.00
IUUC-Sly-110857	Solanum lycopersicum	80.95	3.00e-71	259.00
IUUC-Stu-112436	Solanum tuberosum	80.95	6.00e-72	262.00
IUUC-Sbi-114840	Sorghum bicolor	80.95	1.00e-71	261.00
IUUC-Ssc-115391	Sus scrofa	99.32	1.00e-85	307.00
IUUC-Tsy-118832	Tarsius syrichta	96.60	1.00e-82	297.00
IUUC-Tca-121542	Theobroma cacao	80.95	4.00e-72	263.00
IUUC-Tae-123340	Triticum aestivum	81.63	3.00e-72	263.00
IUUC-Tme-126912	Tuber melanosporum	81.63	5.00e-72	262.00
IUUC-Tbe-128122	Tupaia belangeri	96.77	3.00e-61	226.00
IUUC-Vda-129695	Verticillium dahliae	85.03	2.00e-74	270.00
IUUC-Xtr-132238	Xenopus tropicalis	97.28	3.00e-84	303.00
IUUC-Yli-134353	Yarrowia lipolytica	78.91	3.00e-71	260.00
IUUC-Zma-135267	Zea mays	79.59	4.00e-62	229.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence