iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ata-000201

Ensembl Protein ID

EMT02979

UniProt Accession

N1QTB5; N1QTB5_AEGTA

Genbank Protein ID

EMT02979.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

KD613879

Gene Name

F775_30868

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
F775_30868	EMT02979	EMT02979

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.80e-36	121.9	16	52
UBD/Beta-Prp	2.40e-70	237.8	2	289

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW+++t+++l
   Q: 16   HDGPVRGVHFhKTqPLFVSGGDDYKIKVWNYKTHRCL 52
           99*********4459********************98 PP

UBD/Beta-Prp

   S: 37   wdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghd 137
           wd+++g+ll ++ +h+++v+ v f+++++++v+g++D+ ikvw+++t  c+ tl+gh d++++++f+ +  ++vs+s+d+tirvw++++++c+  +l+gh+
   Q: 2    WDYRMGTLLDRFDEHDGPVRGVHFHKTQPLFVSGGDDYKIKVWNYKTHRCLFTLHGHLDYIRTVQFHDEHPWIVSASDDQTIRVWNWQSRTCVA-VLTGHN 101
           **********************************************************************************************.****** PP
   S: 138  gvvncvvvhpdgnllvsGslDrtvrlWdl..........................ktgkllrtl.......tgghtdsvyslsfdsngkelvsgsldgtvk 205
           + v+c+++hp+++l+vs+slD+tvr+Wd+                                           +gh++ v++ sf+++ + +vsg++d++vk
   Q: 102  HYVMCASFHPKEDLVVSASLDQTVRVWDIgalrkkssspaddimrltqmntdlfgG-------IdavvkyvLEGHDRGVNWASFHPTLPLIVSGADDRQVK 195
           **************************************999999666655555553.......04444445555*************************** PP
   S: 206  lwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           lw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+sir+Wd ++++ ++t+ +++++++  a+ +++ n l++g  ds   ++kl++++p
   Q: 196  LWRMNDTKAweVDTLRGHMNNVSCVLFHAKQDIIVSNSEDKSIRVWDATKRTGIQTFRREHDRFWVLAA-HPEMNLLAAG-HDSGMIVFKLERERP 289
           *****777668**********************************************************.6666655555.689999999988765 PP

Organism

Aegilops tauschii

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MWDYRMGTLL DRFDEHDGPV RGVHFHKTQP LFVSGGDDYK IKVWNYKTHR CLFTLHGHLD 60
YIRTVQFHDE HPWIVSASDD QTIRVWNWQS RTCVAVLTGH NHYVMCASFH PKEDLVVSAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGGACT ACCGCATGGG CACCCTCCTC GACCGCTTCG ACGAGCACGA CGGCCCCGTC 60
CGCGGCGTCC ACTTCCACAA GACACAGCCG CTCTTCGTAT CCGGAGGTAC TACCCTCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

KEGG

ats:F775_30868

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003385	Anas platyrhynchos	49.58	0.00e+00	1030.00
IUUC-Afu-008964	Aspergillus fumigatus	47.38	0.00e+00	1077.00
IUUC-Bdi-014214	Brachypodium distachyon	95.19	0.00e+00	2316.00
IUUC-Bol-015925	Brassica oleracea	74.81	0.00e+00	1826.00
IUUC-Cho-024704	Choloepus hoffmanni	42.41	4.00e-168	584.00
IUUC-Cme-027222	Cyanidioschyzon merolae	42.65	2.00e-146	513.00
IUUC-Dme-031945	Drosophila melanogaster	51.20	0.00e+00	1176.00
IUUC-Eeu-034874	Erinaceus europaeus	41.99	0.00e+00	655.00
IUUC-Hvu-047556	Hordeum vulgare	99.24	0.00e+00	2406.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	45.93	0.00e+00	753.00
IUUC-Opr-070952	Ochotona princeps	41.97	0.00e+00	650.00
IUUC-Ome-081668	Oryza meridionalis	82.42	0.00e+00	1864.00
IUUC-Sar-113313	Sorex araneus	41.98	0.00e+00	637.00
IUUC-Tgu-117109	Taeniopygia guttata	50.00	5.00e-103	367.00
IUUC-Tca-121545	Theobroma cacao	77.82	0.00e+00	1939.00
IUUC-Tae-125732	Triticum aestivum	99.92	0.00e+00	2405.00
IUUC-Tur-126016	Triticum urartu	99.48	0.00e+00	2318.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence