iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bdi-014214

Ensembl Protein ID

BRADI2G55640.1

UniProt Accession

I1HTL7; I1HTL7_BRADI

Genbank Protein ID

KQK10705.1; KQK10706.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

CM000881; CM000881

Gene Name

LOC100841413; BRADI_2g55640

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
BRADI2G55640	BRADI2G55640.1	BRADI2G55640.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.50e-39	131.6	50	86
UBD/Beta-Prp	4.40e-78	263.0	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW+++t+++l
   Q: 50   HDGPVRGVHFhKTqPLFVSGGDDYKIKVWNYKTHRCL 86
           99*********4459********************98 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvl 98
           t +++++++++ ++f+p +++++++  +g ++ wd+++g+ll ++ +h+++v+ v f+++++++v+g++D+ ikvw+++t  c+ tl+gh d+++
   Q: 3    TKFETKSNRVKGLAFHPRRPWILASLHSGVVQMWDYRMGTLLDRFDEHDGPVRGVHFHKTQPLFVSGGDDYKIKVWNYKTHRCLFTLHGHLDYIR 97
           67889999*************************************************************************************** PP
   S: 99   slsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..........................k 167
           +++f+ +  ++vs+s+d+tir+w++++++c+  +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+                           
   Q: 98   TVQFHDEHPWIVSASDDQTIRIWNWQSRTCVA-VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIgalrkksaspaddimrltqmntdlfgG 191
           ********************************.********************************************999999666655555553 PP
   S: 168  tgkllrtl.......tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrs 253
                           +gh++ v++ sf+++ + +vsg++d++vklw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+sir+Wd ++
   Q: 192  -------IdavvkyvLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHMNNVSCVLFHAKQDIIVSNSEDKSIRVWDATK 279
           .......04444555555********************************777668*************************************** PP
   S: 254  gdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           ++ ++t+ +++++++  a+ +++ n l++g  ds   ++kl++++p
   Q: 280  RTGIQTFRREHDRFWILAA-HPEMNLLAAG-HDSGMIVFKLERERP 323
           *******************.6666655555.689999999988765 PP

Organism

Brachypodium distachyon

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLAFHPR RPWILASLHS GVVQMWDYRM GTLLDRFDEH DGPVRGVHFH 60
KTQPLFVSGG DDYKIKVWNY KTHRCLFTLH GHLDYIRTVQ FHDEHPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGACCA AGTTCGAGAC CAAGAGCAAC CGCGTCAAGG GCCTCGCCTT CCACCCGCGC 60
CGCCCATGGA TCCTCGCCAG TCTCCACAGC GGGGTCGTCC AGATGTGGGA CTACCGCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

bdi:100841413

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000201	Aegilops tauschii	95.19	0.00e+00	2322.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	68.87	0.00e+00	1226.00
IUUC-Cme-027222	Cyanidioschyzon merolae	32.62	2.00e-163	570.00
IUUC-Dre-027421	Danio rerio	53.32	0.00e+00	1321.00
IUUC-Gmo-039602	Gadus morhua	50.12	0.00e+00	1220.00
IUUC-Hvu-047556	Hordeum vulgare	95.32	0.00e+00	2401.00
IUUC-Laf-053510	Loxodonta africana	54.37	0.00e+00	1364.00
IUUC-Mvi-060336	Microbotryum violaceum	50.81	0.00e+00	1202.00
IUUC-Pca-100413	Procavia capensis	59.71	0.00e+00	688.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	44.20	0.00e+00	1046.00
IUUC-Tgu-117109	Taeniopygia guttata	44.68	2.00e-106	378.00
IUUC-Tae-123688	Triticum aestivum	95.32	0.00e+00	2402.00
IUUC-Tur-126016	Triticum urartu	94.87	0.00e+00	2236.00
IUUC-Xtr-132857	Xenopus tropicalis	51.21	0.00e+00	1242.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence