iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067311

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02041716

Gene Name

MLST8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000003950.2	ENSMLUT00000003948.2	ENSMLUP00000003595.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-31	106.5	230	260
UBD/Beta-Prp	5.80e-41	140.6	140	333

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           Ht     ++f +d tll+++s D t+k+W++
   Q: 230  HTRYALQCRFsPDsTLLATCSADQTCKIWRT 260
           888888999**999***************96 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls........tgkcvhtlk 91
           ++i+cv+ +p++  l++g ++g i +wd++t    + + + e  +t+  ++pd+++++ + + ++ +vw+l         +  +  ++ 
   Q: 140  APINCVCLHPNQAELIVGDQSGAIHIWDLKTDHNEQLIPEPEVSITSAHIDPDASYMAAVNSTGNCYVWNLTggigdevtQLIPKTKIP 228
           699****************************8886666999999*************************99988777643333333444 PP
   S: 92   ghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllr 173
           +h++++l ++fsp++  l++ s+d+t ++w +++ + + e       + +  +g+ ++ ++++d++++v++s D+  rlW+++tg++ r
   Q: 229  AHTRYALQCRFSPDSTLLATCSADQTCKIWRTSNFSLMTElsikssnPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVETGEIKR 317
           9*************************************99*****9999999************************************* PP
   S: 174  tltgghtdsvyslsfds 190
           +  g h+++v +l+f++
   Q: 318  EYGG-HQKAVVCLAFND 333
           **88.*********987 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MNTSPGTVGS DPVILATAGY DHTVRFWQAH SGICTRTVQH QDSVSSAGKV NALEITPDRS 60
MIAAAGYQHI RMYDLNSNNP NPIISYDGVN KNIASVGFHE DGRWMYTGGE DCTARIWDLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAACACAT CCCCAGGCAC TGTGGGCAGT GACCCGGTCA TCTTGGCTAC TGCGGGCTAT 60
GACCACACCG TGCGGTTTTG GCAGGCCCAC AGCGGGATCT GCACTCGCAC GGTGCAGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0031931--C:TORC1 complex
GO:0031932--C:TORC2 complex
GO:0043539--F:protein serine/threonine kinase activator activity
GO:0030838--P:positive regulation of actin filament polymerization
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0032008--P:positive regulation of TOR signaling
GO:0043087--P:regulation of GTPase activity
GO:0038202--P:TORC1 signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000595	Aegilops tauschii	47.85	1.00e-81	296.00
IUUC-Aml-001813	Ailuropoda melanoleuca	96.44	0.00e+00	668.00
IUUC-Atr-002512	Amborella trichopoda	45.40	1.00e-76	279.00
IUUC-Apl-003495	Anas platyrhynchos	89.27	1.00e-152	531.00
IUUC-Aca-004613	Anolis carolinensis	91.10	0.00e+00	639.00
IUUC-Aly-006340	Arabidopsis lyrata	44.41	1.00e-76	279.00
IUUC-Ath-007273	Arabidopsis thaliana	44.10	6.00e-76	277.00
IUUC-Ago-007737	Ashbya gossypii	45.20	6.00e-79	287.00
IUUC-Acl-008090	Aspergillus clavatus	45.56	2.00e-56	213.00
IUUC-Afl-008490	Aspergillus flavus	40.10	3.00e-39	155.00
IUUC-Afu-009060	Aspergillus fumigatus	43.40	1.00e-49	190.00
IUUC-Ani-009251	Aspergillus nidulans	45.34	1.00e-56	213.00
IUUC-Ang-009528	Aspergillus niger	43.81	2.00e-72	265.00
IUUC-Aor-010005	Aspergillus oryzae	41.90	1.00e-65	243.00
IUUC-Ate-010423	Aspergillus terreus	45.97	1.00e-56	213.00
IUUC-Ame-011752	Astyanax mexicanus	89.02	0.00e+00	631.00
IUUC-Bgr-012299	Blumeria graminis	40.37	7.00e-67	247.00
IUUC-Bta-013007	Bos taurus	95.77	0.00e+00	655.00
IUUC-Bci-013987	Botrytis cinerea	41.37	6.00e-72	264.00
IUUC-Bdi-014082	Brachypodium distachyon	47.55	2.00e-81	295.00
IUUC-Bol-015088	Brassica oleracea	44.72	1.00e-76	279.00
IUUC-Bra-016682	Brassica rapa	41.67	2.00e-69	255.00
IUUC-Cel-018473	Caenorhabditis elegans	24.50	3.00e-32	132.00
IUUC-Cja-019216	Callithrix jacchus	97.43	1.00e-158	551.00
IUUC-Cfa-021229	Canis familiaris	96.14	0.00e+00	667.00
IUUC-Cpo-022270	Cavia porcellus	96.44	0.00e+00	669.00
IUUC-Cre-022742	Chlamydomonas reinhardtii	46.06	6.00e-82	297.00
IUUC-Csa-023275	Chlorocebus sabaeus	95.85	0.00e+00	665.00
IUUC-Cin-025588	Ciona intestinalis	61.35	2.00e-123	435.00
IUUC-Csv-026252	Ciona savignyi	62.50	2.00e-126	445.00
IUUC-Cgl-026418	Colletotrichum gloeosporioides	43.87	1.00e-73	269.00
IUUC-Cne-027013	Cryptococcus neoformans	42.41	4.00e-70	258.00
IUUC-Cme-027131	Cyanidioschyzon merolae	30.97	7.00e-48	184.00
IUUC-Dre-028424	Danio rerio	88.72	0.00e+00	629.00
IUUC-Dno-029327	Dasypus novemcinctus	96.14	0.00e+00	667.00
IUUC-Dor-030186	Dipodomys ordii	92.98	3.00e-90	324.00
IUUC-Dse-031475	Dothistroma septosporum	41.98	6.00e-71	260.00
IUUC-Dme-031826	Drosophila melanogaster	47.69	3.00e-92	331.00
IUUC-Ete-032252	Echinops telfairi	80.73	9.00e-136	476.00
IUUC-Eca-033889	Equus caballus	96.71	2.00e-138	484.00
IUUC-Fca-035989	Felis catus	95.85	0.00e+00	666.00
IUUC-Fal-036637	Ficedula albicollis	90.80	0.00e+00	639.00
IUUC-Fox-038066	Fusarium oxysporum	45.71	6.00e-77	280.00
IUUC-Fso-038288	Fusarium solani	43.56	4.00e-71	261.00
IUUC-Gmo-039477	Gadus morhua	89.46	0.00e+00	626.00
IUUC-Ggr-039990	Gaeumannomyces graminis	44.38	3.00e-73	268.00
IUUC-Gga-040890	Gallus gallus	90.80	0.00e+00	639.00
IUUC-Gac-041502	Gasterosteus aculeatus	88.72	0.00e+00	629.00
IUUC-Gma-042985	Glycine max	46.01	6.00e-78	284.00
IUUC-Ggo-045629	Gorilla gorilla	96.14	0.00e+00	668.00
IUUC-Hsa-045824	Homo sapiens	94.98	5.00e-168	583.00
IUUC-Hvu-047767	Hordeum vulgare	47.55	1.00e-81	296.00
IUUC-Itr-047932	Ictidomys tridecemlineatus	96.44	0.00e+00	669.00
IUUC-Kpa-049173	Komagataella pastoris	44.27	3.00e-78	285.00
IUUC-Lch-049703	Latimeria chalumnae	90.80	0.00e+00	639.00
IUUC-Lpe-050744	Leersia perrieri	43.56	2.00e-70	259.00
IUUC-Loc-052507	Lepisosteus oculatus	88.72	0.00e+00	628.00
IUUC-Lma-053084	Leptosphaeria maculans	41.76	2.00e-68	252.00
IUUC-Laf-053595	Loxodonta africana	95.25	0.00e+00	662.00
IUUC-Mcc-055634	Macaca mulatta	82.31	0.00e+00	628.00
IUUC-Meu-055925	Macropus eugenii	90.64	1.00e-161	561.00
IUUC-Mor-057131	Magnaporthe oryzae	42.68	4.00e-74	271.00
IUUC-Mpo-057524	Magnaporthe poae	44.07	2.00e-73	268.00
IUUC-Mtr-057980	Medicago truncatula	45.71	5.00e-78	284.00
IUUC-Mla-059082	Melampsora laricipopulina	38.10	2.00e-58	219.00
IUUC-Mga-059552	Meleagris gallopavo	89.97	1.00e-153	535.00
IUUC-Mvi-060504	Microbotryum violaceum	41.39	7.00e-67	248.00
IUUC-Mdo-062886	Monodelphis domestica	91.99	0.00e+00	643.00
IUUC-Mmu-063477	Mus musculus	94.96	0.00e+00	661.00
IUUC-Mac-065439	Musa acuminata	46.63	1.00e-79	289.00
IUUC-Mpu-066708	Mustela putorius furo	96.14	0.00e+00	666.00
IUUC-Nfi-068294	Neosartorya fischeri	43.28	5.00e-50	191.00
IUUC-Ncr-068811	Neurospora crassa	42.64	1.00e-71	263.00
IUUC-Nle-069632	Nomascus leucogenys	96.14	0.00e+00	667.00
IUUC-Opr-071128	Ochotona princeps	91.09	3.00e-106	377.00
IUUC-Ont-071494	Oreochromis niloticus	89.61	0.00e+00	633.00
IUUC-Oan-073298	Ornithorhynchus anatinus	93.12	8.00e-105	372.00
IUUC-Ocu-073983	Oryctolagus cuniculus	95.55	0.00e+00	662.00
IUUC-Oba-076001	Oryza barthii	43.25	5.00e-70	257.00
IUUC-Obr-076833	Oryza brachyantha	46.01	4.00e-78	284.00
IUUC-Ogl-077680	Oryza glaberrima	46.01	3.00e-78	285.00
IUUC-Ogu-078086	Oryza glumaepatula	42.23	4.00e-70	258.00
IUUC-Oin-079336	Oryza indica	46.01	3.00e-78	285.00
IUUC-Olo-080368	Oryza longistaminata	41.87	2.00e-58	218.00
IUUC-Oni-083046	Oryza nivara	43.25	4.00e-70	258.00
IUUC-Opu-084173	Oryza punctata	43.25	5.00e-70	257.00
IUUC-Oru-084599	Oryza rufipogon	43.25	5.00e-70	257.00
IUUC-Osa-086193	Oryza sativa	46.01	3.00e-78	285.00
IUUC-Ola-087216	Oryzias latipes	89.02	0.00e+00	632.00
IUUC-Olu-087852	Ostreococcus lucimarinus	45.40	7.00e-78	283.00
IUUC-Oga-088840	Otolemur garnettii	95.85	0.00e+00	667.00
IUUC-Oar-089294	Ovis aries	95.30	1.00e-169	588.00
IUUC-Ptr-090565	Pan troglodytes	96.14	0.00e+00	667.00
IUUC-Pan-092175	Papio anubis	95.85	0.00e+00	665.00
IUUC-Psi-093180	Pelodiscus sinensis	92.06	5.00e-155	539.00
IUUC-Pma-094705	Petromyzon marinus	80.42	5.00e-166	576.00
IUUC-Pno-095001	Phaeosphaeria nodorum	39.39	1.00e-58	219.00
IUUC-Ppa-095628	Physcomitrella patens	46.63	9.00e-81	293.00
IUUC-Pfo-097128	Poecilia formosa	88.72	0.00e+00	631.00
IUUC-Pab-098386	Pongo abelii	96.14	0.00e+00	667.00
IUUC-Pop-099064	Populus trichocarpa	46.32	1.00e-78	286.00
IUUC-Pca-100971	Procavia capensis	94.31	2.00e-167	580.00
IUUC-Ppe-101871	Prunus persica	46.32	1.00e-78	286.00
IUUC-Pva-102230	Pteropus vampyrus	75.74	2.00e-128	451.00
IUUC-Pgr-103511	Puccinia graminis	39.38	5.00e-61	228.00
IUUC-Ptt-103882	Puccinia triticina	37.33	5.00e-60	224.00
IUUC-Pte-104402	Pyrenophora teres	42.65	2.00e-69	256.00
IUUC-Pyt-104448	Pyrenophora triticirepentis	42.65	2.00e-69	256.00
IUUC-Rno-104880	Rattus norvegicus	94.96	0.00e+00	661.00
IUUC-Sce-106266	Saccharomyces cerevisiae	45.51	2.00e-80	292.00
IUUC-Sha-106966	Sarcophilus harrisii	91.99	0.00e+00	643.00
IUUC-Sja-107797	Schizosaccharomyces japonicus	45.34	9.00e-81	293.00
IUUC-Spo-108366	Schizosaccharomyces pombe	44.10	5.00e-80	290.00
IUUC-Smo-108749	Selaginella moellendorffii	45.57	2.00e-75	275.00
IUUC-Sit-110807	Setaria italica	47.55	1.00e-80	293.00
IUUC-Sly-111879	Solanum lycopersicum	41.39	5.00e-48	184.00
IUUC-Sbi-114551	Sorghum bicolor	47.55	1.00e-80	292.00
IUUC-Sre-114962	Sporisorium reilianum	37.97	4.00e-69	254.00
IUUC-Ssc-115363	Sus scrofa	96.44	0.00e+00	670.00
IUUC-Tgu-116695	Taeniopygia guttata	75.00	5.00e-142	496.00
IUUC-Tru-117999	Takifugu rubripes	87.83	0.00e+00	628.00
IUUC-Tni-119973	Tetraodon nigroviridis	87.83	0.00e+00	628.00
IUUC-Tca-121688	Theobroma cacao	45.87	7.00e-78	283.00
IUUC-Tre-122158	Trichoderma reesei	41.10	3.00e-71	261.00
IUUC-Tvi-122511	Trichoderma virens	43.94	3.00e-73	268.00
IUUC-Tae-124124	Triticum aestivum	47.85	1.00e-81	296.00
IUUC-Tur-126228	Triticum urartu	45.40	1.00e-73	269.00
IUUC-Tme-127100	Tuber melanosporum	46.27	3.00e-82	298.00
IUUC-Ttr-128216	Tursiops truncatus	98.97	4.00e-54	204.00
IUUC-Uma-129358	Ustilago maydis	38.86	1.00e-70	259.00
IUUC-Vda-129756	Verticillium dahliae	43.25	9.00e-75	273.00
IUUC-Vvi-131581	Vitis vinifera	44.48	6.00e-75	274.00
IUUC-Xtr-132363	Xenopus tropicalis	87.54	1.00e-178	619.00
IUUC-Xma-133857	Xiphophorus maculatus	88.72	0.00e+00	631.00
IUUC-Yli-134368	Yarrowia lipolytica	43.96	2.00e-76	278.00
IUUC-Zma-135854	Zea mays	47.55	1.00e-80	293.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence