iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022033

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02007386

Gene Name

STUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000023709.1	ENSCPOT00000020348.1	ENSCPOP00000018165.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	8.40e-27	93.0	226	299

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceenss 74
           ++p+++++ Is+elMr+P+++psGitydr+ Ie++l++ g+ +Pvtr+plt+e+l+Pnl+++++i+a+++en++
   Q: 226  DIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGW 299
           69********************************************************************9986 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MKGKEEKEGS ARMGAGGGSP EKSPSAQELK EQGNRLFVGR KYPEAAACYG RAITRNPLVA 60
VYYTNRALCY LKMQQPEQAL ADCRRALELD GQSVKAHFFL GQCQLEMENY DEAIANLQRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGGGCA AGGAGGAAAA GGAAGGTAGC GCGCGAATGG GTGCTGGTGG CGGCAGCCCA 60
GAGAAGAGCC CTAGCGCACA GGAGCTCAAG GAACAGGGCA ACCGGCTCTT CGTGGGTCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat

Interpro

IPR023114--Elongated_TPR_rpt_dom
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50005--TPR
PS50293--TPR_REGION
PS51698--U_BOX

Pfam

PF04564--U-box

SMART

SM00028--TPR
SM00504--Ubox

Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0070062--C:extracellular exosome
GO:0042405--C:nuclear inclusion body
GO:0005654--C:nucleoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0030018--C:Z disc
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0071218--P:cellular response to misfolded protein
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0032091--P:negative regulation of protein binding
GO:0030512--P:negative regulation of transforming growth factor beta receptor signaling pathway
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0051865--P:protein autoubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031943--P:regulation of glucocorticoid metabolic process
GO:0031647--P:regulation of protein stability
GO:0030579--P:ubiquitin-dependent SMAD protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000537	Aegilops tauschii	36.51	2.00e-38	152.00
IUUC-Aml-001350	Ailuropoda melanoleuca	97.60	2.00e-146	511.00
IUUC-Atr-003168	Amborella trichopoda	35.38	1.00e-30	126.00
IUUC-Apl-003736	Anas platyrhynchos	86.85	2.00e-130	457.00
IUUC-Aca-004751	Anolis carolinensis	84.01	3.00e-143	500.00
IUUC-Aly-006292	Arabidopsis lyrata	34.52	2.00e-44	172.00
IUUC-Ath-007012	Arabidopsis thaliana	32.26	7.00e-42	164.00
IUUC-Acl-008025	Aspergillus clavatus	31.80	1.00e-35	143.00
IUUC-Afl-008721	Aspergillus flavus	31.47	3.00e-33	135.00
IUUC-Afu-008853	Aspergillus fumigatus	33.10	2.00e-35	142.00
IUUC-Ani-009349	Aspergillus nidulans	31.85	1.00e-33	136.00
IUUC-Ang-009674	Aspergillus niger	33.33	1.00e-32	133.00
IUUC-Aor-010014	Aspergillus oryzae	29.89	1.00e-27	116.00
IUUC-Ate-010467	Aspergillus terreus	29.69	1.00e-26	113.00
IUUC-Ame-011215	Astyanax mexicanus	61.09	6.00e-95	340.00
IUUC-Bgr-011971	Blumeria graminis	30.14	3.00e-25	108.00
IUUC-Bta-013025	Bos taurus	96.35	2.00e-174	604.00
IUUC-Bci-013945	Botrytis cinerea	39.51	6.00e-15	74.70
IUUC-Bdi-014483	Brachypodium distachyon	38.77	2.00e-45	175.00
IUUC-Bol-015676	Brassica oleracea	35.02	2.00e-47	183.00
IUUC-Bra-017897	Brassica rapa	32.41	2.00e-29	122.00
IUUC-Cel-018323	Caenorhabditis elegans	40.79	2.00e-55	208.00
IUUC-Cja-019657	Callithrix jacchus	96.84	7.00e-167	579.00
IUUC-Cfa-020470	Canis familiaris	96.97	5.00e-134	469.00
IUUC-Cre-022896	Chlamydomonas reinhardtii	27.97	8.00e-29	120.00
IUUC-Csa-023038	Chlorocebus sabaeus	97.89	3.00e-160	557.00
IUUC-Cin-025381	Ciona intestinalis	53.02	3.00e-88	318.00
IUUC-Cgl-026524	Colletotrichum gloeosporioides	32.62	1.00e-39	156.00
IUUC-Dre-027610	Danio rerio	78.35	2.00e-137	481.00
IUUC-Dno-030087	Dasypus novemcinctus	94.72	2.00e-172	597.00
IUUC-Dor-031029	Dipodomys ordii	92.28	2.00e-152	531.00
IUUC-Dse-031275	Dothistroma septosporum	32.31	7.00e-28	117.00
IUUC-Dme-031856	Drosophila melanogaster	58.06	2.00e-95	341.00
IUUC-Ete-033087	Echinops telfairi	91.91	4.00e-138	483.00
IUUC-Eca-033512	Equus caballus	98.00	3.00e-147	513.00
IUUC-Eeu-034763	Erinaceus europaeus	91.85	4.00e-98	349.00
IUUC-Fca-036460	Felis catus	97.43	1.00e-159	555.00
IUUC-Fal-037441	Ficedula albicollis	87.76	3.00e-149	520.00
IUUC-Fox-038028	Fusarium oxysporum	31.40	2.00e-39	155.00
IUUC-Fso-038323	Fusarium solani	32.62	9.00e-30	123.00
IUUC-Gmo-038511	Gadus morhua	77.00	3.00e-131	461.00
IUUC-Ggr-039964	Gaeumannomyces graminis	33.68	3.00e-28	119.00
IUUC-Gga-040854	Gallus gallus	88.11	1.00e-148	518.00
IUUC-Gac-042175	Gasterosteus aculeatus	76.66	1.00e-128	451.00
IUUC-Gma-044046	Glycine max	35.44	2.00e-43	169.00
IUUC-Ggo-044512	Gorilla gorilla	97.89	3.00e-160	557.00
IUUC-Hsa-046872	Homo sapiens	97.89	3.00e-160	557.00
IUUC-Hvu-047661	Hordeum vulgare	35.29	3.00e-39	155.00
IUUC-Itr-048871	Ictidomys tridecemlineatus	98.60	4.00e-170	590.00
IUUC-Lch-049988	Latimeria chalumnae	82.29	1.00e-133	468.00
IUUC-Lpe-050693	Leersia perrieri	34.78	6.00e-43	167.00
IUUC-Loc-052195	Lepisosteus oculatus	78.43	1.00e-115	409.00
IUUC-Lma-053207	Leptosphaeria maculans	30.29	2.00e-29	124.00
IUUC-Laf-054584	Loxodonta africana	94.39	7.00e-174	602.00
IUUC-Mcc-054689	Macaca mulatta	97.89	3.00e-160	557.00
IUUC-Meu-055998	Macropus eugenii	88.14	7.00e-84	303.00
IUUC-Mor-057116	Magnaporthe oryzae	34.39	1.00e-41	163.00
IUUC-Mtr-057684	Medicago truncatula	33.21	2.00e-38	152.00
IUUC-Mga-059332	Meleagris gallopavo	88.05	5.00e-131	459.00
IUUC-Mmr-061377	Microcebus murinus	97.89	7.00e-160	556.00
IUUC-Mdo-061963	Monodelphis domestica	91.26	5.00e-147	513.00
IUUC-Mmu-063146	Mus musculus	97.37	4.00e-163	566.00
IUUC-Mac-064932	Musa acuminata	33.50	6.00e-28	116.00
IUUC-Mpu-066418	Mustela putorius furo	97.89	5.00e-168	583.00
IUUC-Mlu-067066	Myotis lucifugus	96.37	1.00e-176	612.00
IUUC-Nfi-068601	Neosartorya fischeri	33.10	3.00e-35	142.00
IUUC-Ncr-068761	Neurospora crassa	41.67	3.00e-17	82.00
IUUC-Nle-069374	Nomascus leucogenys	97.89	3.00e-160	557.00
IUUC-Opr-070765	Ochotona princeps	92.90	5.00e-103	366.00
IUUC-Ont-071996	Oreochromis niloticus	80.49	2.00e-131	461.00
IUUC-Oba-075967	Oryza barthii	34.83	2.00e-44	172.00
IUUC-Obr-076440	Oryza brachyantha	34.53	1.00e-31	132.00
IUUC-Ogl-077495	Oryza glaberrima	34.83	2.00e-44	172.00
IUUC-Ogu-078247	Oryza glumaepatula	36.36	4.00e-40	158.00
IUUC-Oin-079376	Oryza indica	34.83	2.00e-44	172.00
IUUC-Olo-081083	Oryza longistaminata	29.83	6.00e-32	130.00
IUUC-Ome-081935	Oryza meridionalis	29.06	5.00e-21	97.40
IUUC-Oni-082535	Oryza nivara	36.36	4.00e-40	158.00
IUUC-Opu-083794	Oryza punctata	34.83	7.00e-44	171.00
IUUC-Oru-085153	Oryza rufipogon	34.83	4.00e-44	171.00
IUUC-Osa-085936	Oryza sativa	33.77	8.00e-17	80.10
IUUC-Ola-087081	Oryzias latipes	75.83	4.00e-135	474.00
IUUC-Olu-087790	Ostreococcus lucimarinus	32.14	4.00e-31	128.00
IUUC-Oga-088331	Otolemur garnettii	97.69	1.00e-170	591.00
IUUC-Oar-089987	Ovis aries	93.75	6.00e-141	493.00
IUUC-Ptr-090855	Pan troglodytes	97.89	3.00e-160	557.00
IUUC-Pan-092801	Papio anubis	92.28	4.00e-158	550.00
IUUC-Psi-093393	Pelodiscus sinensis	86.85	8.00e-131	459.00
IUUC-Pma-094680	Petromyzon marinus	69.64	2.00e-114	404.00
IUUC-Pno-094913	Phaeosphaeria nodorum	33.79	1.00e-35	143.00
IUUC-Ppa-095508	Physcomitrella patens	32.71	1.00e-43	170.00
IUUC-Pfo-096850	Poecilia formosa	76.16	2.00e-128	451.00
IUUC-Pab-097963	Pongo abelii	97.89	3.00e-160	557.00
IUUC-Pop-098805	Populus trichocarpa	42.86	8.00e-25	106.00
IUUC-Pca-100788	Procavia capensis	95.38	4.00e-176	610.00
IUUC-Ppe-101221	Prunus persica	34.39	2.00e-44	172.00
IUUC-Pva-103076	Pteropus vampyrus	96.37	1.00e-175	608.00
IUUC-Pte-104237	Pyrenophora teres	31.47	1.00e-33	137.00
IUUC-Pyt-104468	Pyrenophora triticirepentis	31.47	8.00e-34	137.00
IUUC-Rno-105204	Rattus norvegicus	97.37	2.00e-163	568.00
IUUC-Sha-106579	Sarcophilus harrisii	86.33	2.00e-126	444.00
IUUC-Smo-109525	Selaginella moellendorffii	36.17	3.00e-42	164.00
IUUC-Sit-110072	Setaria italica	35.14	4.00e-41	161.00
IUUC-Sly-111473	Solanum lycopersicum	37.01	6.00e-45	174.00
IUUC-Stu-112353	Solanum tuberosum	36.79	2.00e-43	169.00
IUUC-Sbi-114250	Sorghum bicolor	35.76	5.00e-45	174.00
IUUC-Ssc-115416	Sus scrofa	96.37	5.00e-176	609.00
IUUC-Tgu-117272	Taeniopygia guttata	93.52	5.00e-57	211.00
IUUC-Tru-117777	Takifugu rubripes	76.49	6.00e-130	456.00
IUUC-Tni-120572	Tetraodon nigroviridis	76.49	8.00e-131	459.00
IUUC-Tca-121149	Theobroma cacao	38.06	3.00e-51	194.00
IUUC-Tre-122230	Trichoderma reesei	33.21	2.00e-32	132.00
IUUC-Tvi-122678	Trichoderma virens	35.61	1.00e-42	166.00
IUUC-Tae-122986	Triticum aestivum	33.69	3.00e-42	165.00
IUUC-Tur-126009	Triticum urartu	35.20	1.00e-37	150.00
IUUC-Tme-126948	Tuber melanosporum	35.94	2.00e-40	159.00
IUUC-Ttr-129031	Tursiops truncatus	94.39	3.00e-168	583.00
IUUC-Vda-130023	Verticillium dahliae	32.97	3.00e-40	158.00
IUUC-Vpa-130192	Vicugna pacos	35.04	3.00e-10	59.30
IUUC-Vvi-131091	Vitis vinifera	49.44	1.00e-25	108.00
IUUC-Xtr-132871	Xenopus tropicalis	83.21	9.00e-131	459.00
IUUC-Xma-134220	Xiphophorus maculatus	79.09	5.00e-129	453.00
IUUC-Yli-134462	Yarrowia lipolytica	28.27	2.00e-28	119.00
IUUC-Zma-135773	Zea mays	36.03	2.00e-45	175.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence