iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-028529

Ensembl Protein ID

ENSDARP00000079110.4

UniProt Accession

A5PN22; A5PN22_DANRE

Genbank Protein ID

ENSDARP00000079110

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

BX927261

Gene Name

wdr44

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000060249.5	ENSDART00000084675.5	ENSDARP00000079110.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-24	86.3	639	671
UBD/Beta-Prp	2.80e-41	142.5	487	806

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           H d vt++af   +d++++sGs Dg++++W++ 
   Q: 639  HIDFVTAIAFhprDDRYFLSGSLDGKLRLWNIP 671
           8888********555****************75 PP

UBD/Beta-Prp

   S: 37   wdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvwdls.......................................... 82
           +d+++ k+++ l  +h ++v+++kfs+ g +l+t+++D+++++w l+                                          
   Q: 487  FDFDQIKVVQDLsGEHMGAVWTMKFSHCGRLLATAGQDNIVRIWVLKnaydyfnnmrikyntegrvspspsqeslcssksdteggfgaa 575
           57889999999*5579999*************************66666668899999999**************************** PP
   S: 83   .............tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGsl 157
                           ++ ++kgh++++l+ls+s+ +++l+s s d+t+r+w+++ ++cl  +  +h ++v+ +++hp + +++ sGsl
   Q: 576  vedadtedrnvpfRQVPFCKYKGHTADLLDLSWSK-NYFLLSSSMDKTVRLWHISRRECL--CCFQHIDFVTAIAFHPRDdRYFLSGSL 661
           ***********999999******************.9***********************..7888999******************** PP
   S: 158  DrtvrlWdlktgk..llrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq.....tgecvrtlnght...dnvksvrfspnder 236
           D+++rlW+++ +k  l  +  g +t+ ++  +f +ngk+ v g +dg+ +++d +     t+  vr+ +g +   + ++ ++ +p ++ 
   Q: 662  DGKLRLWNIPDKKvaLWNEVDG-QTRLITAANFCQNGKYAVIGTYDGRCIFYDTErlkyhTQIHVRSTRGRNrvgRKITGIEPLPGENK 749
           *********6666114555687.********************************66664333466666666677899999999***** PP
   S: 237  lvsgssDgsiriWdlrsgdllktlqlhnssvisvav.lsfgdnvlvlgsedskvniw 292
           ++++s D  ir++dlr   l  ++++  +s++ +++ +s +++++v+gsed+ v iw
   Q: 750  ILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKAsFSHDYSYIVSGSEDKYVYIW 806
           ****************************9999999967777************9999 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MASDTSDTEE FYDAAEDVNF TPSPHASPAK FELPQPGGPT ESVVQEVAAG LAQPEPRHDD 60
SLQIIDSIIE ESQKSGVEEE LLRTEDTCEA SSEGEKPEAE DCSVEETPAP EVLVVVLPED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAGCAGTGG CGGCGGCCTC TGTATGCAGC CCGGGCTCAA TGGCGTCCGA CACCAGCGAC 60
ACGGAGGAGT TTTACGATGC GGCGGAGGAT GTCAACTTCA CTCCCTCGCC CCACGCGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

KEGG

dre:569045

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000228	Aegilops tauschii	38.04	6.00e-59	222.00
IUUC-Aml-001198	Ailuropoda melanoleuca	79.02	0.00e+00	1057.00
IUUC-Atr-002683	Amborella trichopoda	40.06	2.00e-56	214.00
IUUC-Apl-003781	Anas platyrhynchos	80.80	0.00e+00	1080.00
IUUC-Aca-005216	Anolis carolinensis	70.24	0.00e+00	1087.00
IUUC-Aly-005741	Arabidopsis lyrata	31.42	1.00e-53	204.00
IUUC-Ath-007572	Arabidopsis thaliana	40.89	8.00e-56	212.00
IUUC-Ago-007814	Ashbya gossypii	33.43	7.00e-45	175.00
IUUC-Acl-008290	Aspergillus clavatus	37.27	3.00e-59	223.00
IUUC-Afl-008536	Aspergillus flavus	41.67	3.00e-79	290.00
IUUC-Afu-008761	Aspergillus fumigatus	42.32	2.00e-84	307.00
IUUC-Ani-009270	Aspergillus nidulans	40.83	6.00e-80	292.00
IUUC-Ang-009627	Aspergillus niger	40.66	4.00e-81	296.00
IUUC-Aor-010153	Aspergillus oryzae	41.67	3.00e-79	290.00
IUUC-Ate-010263	Aspergillus terreus	40.71	3.00e-82	300.00
IUUC-Ame-011096	Astyanax mexicanus	83.03	0.00e+00	1314.00
IUUC-Bgr-012014	Blumeria graminis	44.44	3.00e-74	273.00
IUUC-Bta-012991	Bos taurus	81.21	0.00e+00	1061.00
IUUC-Bci-013651	Botrytis cinerea	44.98	7.00e-92	332.00
IUUC-Bdi-014809	Brachypodium distachyon	35.86	8.00e-63	235.00
IUUC-Bol-016459	Brassica oleracea	31.47	1.00e-57	218.00
IUUC-Bra-017269	Brassica rapa	31.25	2.00e-51	197.00
IUUC-Cel-018681	Caenorhabditis elegans	43.68	2.00e-121	431.00
IUUC-Cja-019169	Callithrix jacchus	78.88	0.00e+00	1054.00
IUUC-Cfa-020909	Canis familiaris	67.20	0.00e+00	1068.00
IUUC-Cpo-021357	Cavia porcellus	79.47	0.00e+00	1019.00
IUUC-Cre-022638	Chlamydomonas reinhardtii	34.54	3.00e-20	92.40
IUUC-Csa-023121	Chlorocebus sabaeus	66.99	0.00e+00	1047.00
IUUC-Cin-025347	Ciona intestinalis	52.27	7.00e-171	593.00
IUUC-Csv-025844	Ciona savignyi	57.09	1.00e-162	566.00
IUUC-Cgl-026610	Colletotrichum gloeosporioides	41.61	1.00e-80	294.00
IUUC-Cme-027130	Cyanidioschyzon merolae	35.32	5.00e-61	229.00
IUUC-Dno-028930	Dasypus novemcinctus	78.07	4.00e-166	578.00
IUUC-Dor-030184	Dipodomys ordii	76.50	0.00e+00	962.00
IUUC-Dse-031178	Dothistroma septosporum	39.14	4.00e-90	326.00
IUUC-Dme-032135	Drosophila melanogaster	57.12	0.00e+00	692.00
IUUC-Ete-032457	Echinops telfairi	71.36	0.00e+00	845.00
IUUC-Eca-033319	Equus caballus	66.67	0.00e+00	1052.00
IUUC-Eeu-035325	Erinaceus europaeus	68.95	0.00e+00	745.00
IUUC-Fca-036159	Felis catus	77.55	0.00e+00	1004.00
IUUC-Fal-037153	Ficedula albicollis	79.36	0.00e+00	1036.00
IUUC-Fox-037744	Fusarium oxysporum	42.16	2.00e-55	209.00
IUUC-Fso-038143	Fusarium solani	41.30	3.00e-78	286.00
IUUC-Gmo-039226	Gadus morhua	73.33	0.00e+00	1107.00
IUUC-Ggr-039923	Gaeumannomyces graminis	42.01	1.00e-78	288.00
IUUC-Gga-040349	Gallus gallus	81.79	0.00e+00	1089.00
IUUC-Gac-041620	Gasterosteus aculeatus	76.44	0.00e+00	1184.00
IUUC-Gma-044105	Glycine max	40.91	3.00e-59	223.00
IUUC-Ggo-044646	Gorilla gorilla	66.60	0.00e+00	1047.00
IUUC-Hsa-046353	Homo sapiens	80.83	0.00e+00	1045.00
IUUC-Hvu-047791	Hordeum vulgare	45.41	2.00e-54	207.00
IUUC-Itr-048620	Ictidomys tridecemlineatus	85.09	0.00e+00	1032.00
IUUC-Kpa-049365	Komagataella pastoris	33.14	4.00e-47	183.00
IUUC-Lch-049794	Latimeria chalumnae	70.05	0.00e+00	1123.00
IUUC-Lpe-050902	Leersia perrieri	37.03	3.00e-54	207.00
IUUC-Loc-052691	Lepisosteus oculatus	82.81	0.00e+00	1144.00
IUUC-Lma-053232	Leptosphaeria maculans	38.19	5.00e-83	302.00
IUUC-Laf-054066	Loxodonta africana	67.35	0.00e+00	1058.00
IUUC-Mcc-055055	Macaca mulatta	67.09	0.00e+00	1048.00
IUUC-Meu-056678	Macropus eugenii	58.65	0.00e+00	867.00
IUUC-Mor-057274	Magnaporthe oryzae	42.66	7.00e-79	289.00
IUUC-Mpo-057592	Magnaporthe poae	42.01	5.00e-78	286.00
IUUC-Mtr-058330	Medicago truncatula	39.58	1.00e-53	204.00
IUUC-Mla-059075	Melampsora laricipopulina	35.63	1.00e-33	138.00
IUUC-Mga-059659	Meleagris gallopavo	81.18	0.00e+00	1074.00
IUUC-Mvi-060254	Microbotryum violaceum	48.28	3.00e-81	297.00
IUUC-Mmr-060832	Microcebus murinus	80.93	0.00e+00	1060.00
IUUC-Mdo-062300	Monodelphis domestica	80.52	0.00e+00	1112.00
IUUC-Mmu-064277	Mus musculus	80.26	0.00e+00	1031.00
IUUC-Mac-064884	Musa acuminata	32.46	8.00e-57	216.00
IUUC-Mpu-065914	Mustela putorius furo	81.36	0.00e+00	1063.00
IUUC-Mlu-067853	Myotis lucifugus	68.71	0.00e+00	1056.00
IUUC-Nfi-068449	Neosartorya fischeri	35.92	2.00e-58	221.00
IUUC-Ncr-068874	Neurospora crassa	45.53	3.00e-83	303.00
IUUC-Nle-069802	Nomascus leucogenys	66.88	0.00e+00	1051.00
IUUC-Opr-071139	Ochotona princeps	87.03	4.00e-159	555.00
IUUC-Ont-072128	Oreochromis niloticus	74.41	0.00e+00	1219.00
IUUC-Oan-072824	Ornithorhynchus anatinus	68.85	0.00e+00	807.00
IUUC-Ocu-074311	Oryctolagus cuniculus	66.38	0.00e+00	1060.00
IUUC-Oba-075039	Oryza barthii	37.03	3.00e-53	203.00
IUUC-Obr-076536	Oryza brachyantha	37.53	3.00e-54	206.00
IUUC-Ogl-077530	Oryza glaberrima	38.33	6.00e-59	222.00
IUUC-Ogu-078866	Oryza glumaepatula	37.03	2.00e-53	204.00
IUUC-Oin-080074	Oryza indica	38.33	6.00e-59	222.00
IUUC-Olo-080838	Oryza longistaminata	34.45	5.00e-38	153.00
IUUC-Ome-081525	Oryza meridionalis	36.78	7.00e-53	202.00
IUUC-Oni-082288	Oryza nivara	37.03	2.00e-53	204.00
IUUC-Opu-083458	Oryza punctata	37.03	4.00e-53	202.00
IUUC-Oru-085014	Oryza rufipogon	37.03	2.00e-53	204.00
IUUC-Osa-085616	Oryza sativa	38.33	5.00e-59	222.00
IUUC-Ola-086963	Oryzias latipes	74.03	0.00e+00	1125.00
IUUC-Olu-087651	Ostreococcus lucimarinus	50.26	1.00e-51	196.00
IUUC-Oga-088623	Otolemur garnettii	79.16	0.00e+00	1062.00
IUUC-Oar-090357	Ovis aries	80.93	0.00e+00	1060.00
IUUC-Pan-092290	Papio anubis	74.39	0.00e+00	1010.00
IUUC-Psi-094089	Pelodiscus sinensis	81.59	0.00e+00	1115.00
IUUC-Pma-094528	Petromyzon marinus	73.13	0.00e+00	667.00
IUUC-Pno-094806	Phaeosphaeria nodorum	37.99	1.00e-83	304.00
IUUC-Ppa-095184	Physcomitrella patens	40.42	2.00e-62	234.00
IUUC-Pfo-097366	Poecilia formosa	74.41	0.00e+00	1230.00
IUUC-Pab-098364	Pongo abelii	66.56	0.00e+00	1050.00
IUUC-Pop-099728	Populus trichocarpa	35.07	7.00e-55	209.00
IUUC-Pca-100159	Procavia capensis	72.38	0.00e+00	913.00
IUUC-Ppe-101184	Prunus persica	30.41	3.00e-52	200.00
IUUC-Pva-102846	Pteropus vampyrus	76.98	0.00e+00	974.00
IUUC-Pte-104369	Pyrenophora teres	37.91	1.00e-83	305.00
IUUC-Pyt-104811	Pyrenophora triticirepentis	38.04	9.00e-84	305.00
IUUC-Rno-105467	Rattus norvegicus	81.64	0.00e+00	1031.00
IUUC-Sce-106277	Saccharomyces cerevisiae	36.98	2.00e-47	184.00
IUUC-Sha-106778	Sarcophilus harrisii	79.42	0.00e+00	1065.00
IUUC-Sja-107954	Schizosaccharomyces japonicus	42.05	2.00e-85	310.00
IUUC-Spo-108181	Schizosaccharomyces pombe	48.22	3.00e-84	306.00
IUUC-Smo-108748	Selaginella moellendorffii	44.69	5.00e-60	226.00
IUUC-Sit-110115	Setaria italica	41.51	3.00e-62	233.00
IUUC-Sly-111804	Solanum lycopersicum	39.25	3.00e-50	194.00
IUUC-Stu-111949	Solanum tuberosum	39.75	7.00e-53	202.00
IUUC-Sar-112958	Sorex araneus	79.57	8.00e-88	318.00
IUUC-Sbi-114454	Sorghum bicolor	38.36	6.00e-61	229.00
IUUC-Sre-114996	Sporisorium reilianum	37.69	4.00e-52	199.00
IUUC-Tgu-116614	Taeniopygia guttata	79.57	0.00e+00	1080.00
IUUC-Tru-117808	Takifugu rubripes	76.56	0.00e+00	1154.00
IUUC-Tsy-118845	Tarsius syrichta	70.87	4.00e-156	545.00
IUUC-Tni-120013	Tetraodon nigroviridis	74.14	0.00e+00	1180.00
IUUC-Tca-121635	Theobroma cacao	35.11	5.00e-52	199.00
IUUC-Tre-122175	Trichoderma reesei	43.90	7.00e-72	265.00
IUUC-Tvi-122654	Trichoderma virens	45.06	1.00e-78	288.00
IUUC-Tae-122935	Triticum aestivum	38.17	9.00e-62	232.00
IUUC-Tur-126660	Triticum urartu	32.65	8.00e-61	228.00
IUUC-Tme-126882	Tuber melanosporum	43.74	4.00e-96	346.00
IUUC-Tbe-127531	Tupaia belangeri	87.71	3.00e-159	555.00
IUUC-Ttr-128970	Tursiops truncatus	78.84	0.00e+00	1022.00
IUUC-Uma-129369	Ustilago maydis	36.06	6.00e-45	176.00
IUUC-Vda-129935	Verticillium dahliae	44.83	5.00e-79	289.00
IUUC-Vpa-130109	Vicugna pacos	79.37	0.00e+00	941.00
IUUC-Vvi-130908	Vitis vinifera	36.56	3.00e-50	194.00
IUUC-Xtr-132836	Xenopus tropicalis	81.08	0.00e+00	1066.00
IUUC-Xma-134131	Xiphophorus maculatus	73.63	0.00e+00	1226.00
IUUC-Yli-134376	Yarrowia lipolytica	37.50	4.00e-63	236.00
IUUC-Zma-135851	Zea mays	38.24	3.00e-55	210.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence