iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093818

Ensembl Protein ID

ENSPSIP00000015983.1

UniProt Accession

K7G6S2; K7G6S2_PELSI

Genbank Protein ID

ENSPSIP00000015983

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AGCU01130170

Gene Name

UCHL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000014142.1	ENSPSIT00000016058.1	ENSPSIP00000015983.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	6.90e-60	203.2	2	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvi 95
           +w ++e +P++++++++++gv   +++ ++ + +++ l++++ p ++llllF+++ ++e++rk+q++    e +++++ ++++f+kq++
   Q: 2    QWQPMEINPEMLNKVLSRLGVAPGWHFVDVLGFEEDVLSSVPTPSCALLLLFPLTAQHENFRKKQIE----ELKGQEVSSKVYFLKQTV 86
           8****************************************************************99....99**************** PP
   S: 96   gNsCatyAllsvllncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsy 183
           gNsC+t++l+++++n++dkl +d G+ l++++++t   spe++a+ l+n+++++ +hn++a++++++ +e          k +fhf+++
   Q: 87   GNSCGTIGLIHAVANNQDKLvFDEGSALKKFLKETADLSPEERAKRLENNKAIQEVHNAVAQEGQCQVEED---------KVNFHFILF 166
           ******************************************************************99954.........589****** PP
   S: 184  vningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaiva 243
            n++g+lyeldg++pfP+++g+++++  lk  +k +r+f+er    e +e+rf+++a+++
   Q: 167  ANVDGHLYELDGRMPFPVNHGESSDDLLLKASAKICRQFTER----ERGEVRFSAVALSK 222
           ******************************************....9********99876 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MQWQPMEINP EMLNKVLSRL GVAPGWHFVD VLGFEEDVLS SVPTPSCALL LLFPLTAQHE 60
NFRKKQIEEL KGQEVSSKVY FLKQTVGNSC GTIGLIHAVA NNQDKLVFDE GSALKKFLKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCACAAGGC TTGGGGGGAA GGGAGGGTAA CCGCAGGGTT CGTAAGGTAC TGTTTTCTCA 60
AGTGTTTTTT TCTTTATTTT TATTAACTAT TTGGTTTGGG GGTTTCTTTT TGAACCATGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR030297--UCHL1

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:1904115--C:axon cytoplasm
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0044306--C:neuron projection terminus
GO:0043025--C:neuronal cell body
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0016874--F:ligase activity
GO:0008242--F:omega peptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007628--P:adult walking behavior
GO:0007412--P:axon target recognition
GO:0019896--P:axonal transport of mitochondrion
GO:0008283--P:cell proliferation
GO:0042755--P:eating behavior
GO:0048747--P:muscle fiber development
GO:0043407--P:negative regulation of MAP kinase activity
GO:0050905--P:neuromuscular process
GO:0016579--P:protein deubiquitination
GO:0002931--P:response to ischemia
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

pss:102451446

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000360	Aegilops tauschii	38.20	1.00e-43	169.00
IUUC-Aml-001376	Ailuropoda melanoleuca	65.50	4.00e-89	320.00
IUUC-Apl-003693	Anas platyrhynchos	75.45	2.00e-98	351.00
IUUC-Aca-004716	Anolis carolinensis	85.71	2.00e-117	414.00
IUUC-Aly-005939	Arabidopsis lyrata	42.79	1.00e-50	192.00
IUUC-Ath-006827	Arabidopsis thaliana	43.24	8.00e-51	192.00
IUUC-Afl-008611	Aspergillus flavus	38.70	8.00e-35	140.00
IUUC-Afu-008945	Aspergillus fumigatus	37.77	3.00e-34	138.00
IUUC-Ang-009691	Aspergillus niger	37.07	6.00e-35	140.00
IUUC-Aor-009961	Aspergillus oryzae	38.70	8.00e-35	140.00
IUUC-Ate-010316	Aspergillus terreus	38.10	1.00e-35	142.00
IUUC-Ame-011806	Astyanax mexicanus	65.47	3.00e-86	310.00
IUUC-Bgr-012125	Blumeria graminis	34.89	3.00e-32	131.00
IUUC-Bta-013521	Bos taurus	66.40	2.00e-90	324.00
IUUC-Bci-013734	Botrytis cinerea	36.64	2.00e-35	142.00
IUUC-Bdi-014330	Brachypodium distachyon	41.96	4.00e-47	181.00
IUUC-Bol-015214	Brassica oleracea	43.69	9.00e-52	196.00
IUUC-Bra-017491	Brassica rapa	44.14	2.00e-52	198.00
IUUC-Cel-018302	Caenorhabditis elegans	36.24	3.00e-33	134.00
IUUC-Cja-019642	Callithrix jacchus	79.02	2.00e-94	338.00
IUUC-Cfa-020442	Canis familiaris	78.22	6.00e-93	332.00
IUUC-Cpo-021723	Cavia porcellus	78.44	2.00e-75	274.00
IUUC-Cre-022599	Chlamydomonas reinhardtii	35.51	9.00e-31	126.00
IUUC-Csa-023626	Chlorocebus sabaeus	79.02	2.00e-94	338.00
IUUC-Cho-024548	Choloepus hoffmanni	74.07	7.00e-34	136.00
IUUC-Cgl-026409	Colletotrichum gloeosporioides	32.34	1.00e-27	115.00
IUUC-Dre-027854	Danio rerio	65.18	6.00e-85	306.00
IUUC-Dno-029325	Dasypus novemcinctus	77.68	9.00e-94	335.00
IUUC-Dor-030114	Dipodomys ordii	77.68	6.00e-103	365.00
IUUC-Dse-031461	Dothistroma septosporum	35.19	3.00e-32	131.00
IUUC-Ete-033092	Echinops telfairi	63.39	2.00e-77	281.00
IUUC-Eeu-034493	Erinaceus europaeus	75.45	2.00e-89	321.00
IUUC-Fal-036693	Ficedula albicollis	82.86	4.00e-103	367.00
IUUC-Fox-037830	Fusarium oxysporum	36.68	8.00e-36	143.00
IUUC-Fso-038259	Fusarium solani	36.56	9.00e-35	142.00
IUUC-Gmo-038848	Gadus morhua	60.38	9.00e-76	275.00
IUUC-Ggr-039832	Gaeumannomyces graminis	35.37	6.00e-29	120.00
IUUC-Gga-041078	Gallus gallus	84.38	6.00e-114	402.00
IUUC-Gac-042064	Gasterosteus aculeatus	63.68	8.00e-83	299.00
IUUC-Gma-043057	Glycine max	44.20	1.00e-44	172.00
IUUC-Ggo-044827	Gorilla gorilla	79.91	8.00e-96	342.00
IUUC-Hsa-045820	Homo sapiens	79.91	8.00e-96	342.00
IUUC-Hvu-047176	Hordeum vulgare	35.11	2.00e-35	142.00
IUUC-Itr-048496	Ictidomys tridecemlineatus	78.57	3.00e-94	337.00
IUUC-Kpa-049123	Komagataella pastoris	34.01	6.00e-25	107.00
IUUC-Lch-050121	Latimeria chalumnae	71.17	2.00e-94	337.00
IUUC-Lpe-051377	Leersia perrieri	43.22	9.00e-42	162.00
IUUC-Loc-052342	Lepisosteus oculatus	68.58	3.00e-91	327.00
IUUC-Laf-053916	Loxodonta africana	76.44	3.00e-92	330.00
IUUC-Mcc-054838	Macaca mulatta	79.02	2.00e-94	338.00
IUUC-Meu-056478	Macropus eugenii	80.36	6.00e-106	375.00
IUUC-Mor-057271	Magnaporthe oryzae	36.68	1.00e-36	145.00
IUUC-Mpo-057343	Magnaporthe poae	30.51	3.00e-20	90.90
IUUC-Mtr-057713	Medicago truncatula	43.30	4.00e-45	174.00
IUUC-Mga-059878	Meleagris gallopavo	82.49	5.00e-106	376.00
IUUC-Mdo-062544	Monodelphis domestica	79.46	1.00e-95	341.00
IUUC-Mmu-063300	Mus musculus	78.12	3.00e-103	367.00
IUUC-Mac-065075	Musa acuminata	40.97	1.00e-44	172.00
IUUC-Mpu-066128	Mustela putorius furo	78.11	1.00e-81	295.00
IUUC-Mlu-067778	Myotis lucifugus	79.46	2.00e-104	370.00
IUUC-Nfi-068320	Neosartorya fischeri	38.20	1.00e-34	139.00
IUUC-Ncr-068673	Neurospora crassa	35.37	3.00e-37	148.00
IUUC-Nle-069686	Nomascus leucogenys	79.46	2.00e-95	341.00
IUUC-Opr-070535	Ochotona princeps	63.39	9.00e-79	285.00
IUUC-Ont-071510	Oreochromis niloticus	61.43	1.00e-81	295.00
IUUC-Ocu-074590	Oryctolagus cuniculus	77.68	5.00e-94	336.00
IUUC-Oba-075098	Oryza barthii	36.65	3.00e-43	167.00
IUUC-Obr-076041	Oryza brachyantha	40.44	7.00e-46	176.00
IUUC-Ogl-076980	Oryza glaberrima	40.44	4.00e-45	174.00
IUUC-Ogu-078978	Oryza glumaepatula	34.80	2.00e-41	162.00
IUUC-Oin-079285	Oryza indica	36.20	1.00e-42	165.00
IUUC-Olo-080671	Oryza longistaminata	36.20	7.00e-42	163.00
IUUC-Ome-081428	Oryza meridionalis	35.29	2.00e-40	158.00
IUUC-Oni-082406	Oryza nivara	36.65	3.00e-43	167.00
IUUC-Opu-083305	Oryza punctata	35.29	3.00e-41	161.00
IUUC-Oru-084969	Oryza rufipogon	36.65	3.00e-43	167.00
IUUC-Osa-085830	Oryza sativa	40.44	4.00e-45	174.00
IUUC-Ola-087552	Oryzias latipes	60.09	9.00e-79	285.00
IUUC-Oga-089013	Otolemur garnettii	66.40	2.00e-89	321.00
IUUC-Oar-089861	Ovis aries	66.40	2.00e-90	324.00
IUUC-Ptr-091536	Pan troglodytes	78.12	3.00e-93	333.00
IUUC-Pan-092909	Papio anubis	79.02	2.00e-94	338.00
IUUC-Pno-094997	Phaeosphaeria nodorum	32.94	1.00e-26	113.00
IUUC-Pfo-097335	Poecilia formosa	60.89	5.00e-80	290.00
IUUC-Pab-098048	Pongo abelii	79.91	8.00e-96	342.00
IUUC-Pop-099282	Populus trichocarpa	41.96	1.00e-43	169.00
IUUC-Pca-100818	Procavia capensis	64.29	1.00e-56	211.00
IUUC-Ppe-101332	Prunus persica	41.52	1.00e-45	176.00
IUUC-Pva-102954	Pteropus vampyrus	79.91	2.00e-92	331.00
IUUC-Pyt-104587	Pyrenophora triticirepentis	35.05	7.00e-32	130.00
IUUC-Rno-105966	Rattus norvegicus	78.12	3.00e-103	367.00
IUUC-Sha-107111	Sarcophilus harrisii	79.52	1.00e-76	277.00
IUUC-Sja-107753	Schizosaccharomyces japonicus	30.40	5.00e-21	94.00
IUUC-Spo-108322	Schizosaccharomyces pombe	33.19	4.00e-27	114.00
IUUC-Smo-109283	Selaginella moellendorffii	42.42	1.00e-45	176.00
IUUC-Sit-110163	Setaria italica	40.89	4.00e-47	181.00
IUUC-Sly-111832	Solanum lycopersicum	45.29	8.00e-51	192.00
IUUC-Stu-112526	Solanum tuberosum	45.74	1.00e-51	195.00
IUUC-Sar-113190	Sorex araneus	56.52	4.00e-26	108.00
IUUC-Sbi-114545	Sorghum bicolor	41.15	3.00e-45	174.00
IUUC-Ssc-115908	Sus scrofa	64.16	1.00e-77	281.00
IUUC-Tgu-117465	Taeniopygia guttata	79.62	1.00e-97	348.00
IUUC-Tru-118565	Takifugu rubripes	59.19	1.00e-70	258.00
IUUC-Tsy-119561	Tarsius syrichta	63.39	1.00e-76	278.00
IUUC-Tre-122149	Trichoderma reesei	37.12	4.00e-38	150.00
IUUC-Tvi-122450	Trichoderma virens	36.68	2.00e-37	149.00
IUUC-Tae-122693	Triticum aestivum	39.56	3.00e-45	175.00
IUUC-Tur-126250	Triticum urartu	38.20	3.00e-43	167.00
IUUC-Tme-126961	Tuber melanosporum	37.34	9.00e-32	129.00
IUUC-Tbe-128048	Tupaia belangeri	79.52	3.00e-76	276.00
IUUC-Ttr-128494	Tursiops truncatus	76.68	7.00e-90	322.00
IUUC-Uma-129382	Ustilago maydis	37.34	9.00e-35	139.00
IUUC-Vda-129850	Verticillium dahliae	32.02	8.00e-27	113.00
IUUC-Vvi-131661	Vitis vinifera	40.09	1.00e-45	176.00
IUUC-Xtr-132286	Xenopus tropicalis	70.54	6.00e-92	329.00
IUUC-Xma-133019	Xiphophorus maculatus	59.64	1.00e-79	288.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence