iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091224

UUCD1 version

UUC-PaT-00457

Ensembl Protein ID

ENSPTRP00000022503.3

UniProt Accession

H2QJS6; H2QJS6_PANTR

Genbank Protein ID

JAA00680.1; JAA18196.1; JAA31492.1; JAA41470.1

Protein Name

RanBP-type and C3HC4-type zinc finger containing 1

Genbank Nucleotide ID

AACZ03122287; GABF01003949; GABD01001608; GABE01003269

Gene Name

RBCK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000013144.6	ENSPTRT00000024395.3	ENSPTRP00000022503.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	2.80e-11	42.7	195	221
ULD/UDP/UBQ/UBQ_Other	7.20e-07	29.0	60	122

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 3    aqWaCsaCTflNePeavkCemCsrpRg 29
            +W+C+ CTf+N+P +++CemC+r R+
   Q: 195  VGWQCPGCTFINKPTRPGCEMCCRARP 221
           68************************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 4    tvksldgseltlk..vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdg 64
            v++++  + t++  v p++tVa LK++++   g+pp  q++++ G+ L +d  tL ++g++++
   Q: 60   SVEDAQMHTVTIWltVRPDMTVASLKDMVFLDYGFPPVLQQWVI-GQRLaRDQETLHSHGVRQN 122
           5666665577777889****************************.55555**********9875 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MDEKTKKAEE MALSLTRAVA GGDEQVAMKC AIWLAEQRVP LSVQLKPEVS PTQDIRLWVS 60
VEDAQMHTVT IWLTVRPDMT VASLKDMVFL DYGFPPVLQQ WVIGQRLARD QETLHSHGVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTGGGGCCT CCCGGGAGGA GAGAGGGCTT TGCCTTGAAA CCCGGGACGC CAGGGGCGCT 60
CCCGCAAGTG GGGGTCCTCC GGGACTTGGA ACGCCCCGGC TGGGTGGTGT CCGGGCGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR002867--IBR_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR027370--Znf-RING_LisH
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50053--UBIQUITIN_2
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00547--ZnF_RBZ

Gene Ontology

GO:0071797--C:LUBAC complex
GO:0043130--F:ubiquitin binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060546--P:negative regulation of necroptotic process
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0042346--P:positive regulation of NF-kappaB import into nucleus
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination
GO:0050852--P:T cell receptor signaling pathway

KEGG

ptr:458025

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001540	Ailuropoda melanoleuca	92.35	0.00e+00	859.00
IUUC-Apl-003627	Anas platyrhynchos	61.54	9.00e-19	84.30
IUUC-Aca-004507	Anolis carolinensis	63.88	4.00e-153	534.00
IUUC-Ame-011008	Astyanax mexicanus	52.95	1.00e-143	503.00
IUUC-Bta-013247	Bos taurus	94.51	0.00e+00	908.00
IUUC-Bci-013637	Botrytis cinerea	25.85	1.00e-12	68.90
IUUC-Cja-018880	Callithrix jacchus	98.04	0.00e+00	941.00
IUUC-Cfa-020477	Canis familiaris	94.51	0.00e+00	910.00
IUUC-Cpo-021558	Cavia porcellus	90.20	0.00e+00	860.00
IUUC-Csa-024129	Chlorocebus sabaeus	98.63	0.00e+00	902.00
IUUC-Cin-025630	Ciona intestinalis	39.67	5.00e-81	294.00
IUUC-Csv-026069	Ciona savignyi	51.20	3.00e-72	264.00
IUUC-Dre-027591	Danio rerio	52.53	2.00e-141	495.00
IUUC-Dno-029015	Dasypus novemcinctus	92.16	0.00e+00	871.00
IUUC-Dor-030313	Dipodomys ordii	82.47	0.00e+00	739.00
IUUC-Ete-032908	Echinops telfairi	81.00	0.00e+00	760.00
IUUC-Eca-034295	Equus caballus	77.14	0.00e+00	723.00
IUUC-Eeu-034454	Erinaceus europaeus	86.10	2.00e-115	409.00
IUUC-Fca-036380	Felis catus	95.10	0.00e+00	913.00
IUUC-Fal-037440	Ficedula albicollis	56.90	3.00e-15	72.80
IUUC-Gmo-038561	Gadus morhua	53.62	4.00e-119	421.00
IUUC-Gga-040198	Gallus gallus	38.12	5.00e-29	121.00
IUUC-Gac-041319	Gasterosteus aculeatus	52.54	8.00e-138	483.00
IUUC-Ggo-044456	Gorilla gorilla	68.46	3.00e-158	551.00
IUUC-Hsa-045738	Homo sapiens	99.80	0.00e+00	902.00
IUUC-Itr-049042	Ictidomys tridecemlineatus	92.75	0.00e+00	867.00
IUUC-Lch-050269	Latimeria chalumnae	44.74	3.00e-114	405.00
IUUC-Loc-052776	Lepisosteus oculatus	49.00	1.00e-136	479.00
IUUC-Laf-054269	Loxodonta africana	91.57	0.00e+00	883.00
IUUC-Mcc-055669	Macaca mulatta	99.41	0.00e+00	915.00
IUUC-Mga-059615	Meleagris gallopavo	54.69	1.00e-17	80.50
IUUC-Mmr-061562	Microcebus murinus	93.60	0.00e+00	778.00
IUUC-Mdo-062263	Monodelphis domestica	77.91	0.00e+00	750.00
IUUC-Mmu-064325	Mus musculus	90.98	0.00e+00	845.00
IUUC-Mpu-066385	Mustela putorius furo	94.51	0.00e+00	908.00
IUUC-Mlu-067000	Myotis lucifugus	91.18	0.00e+00	862.00
IUUC-Nle-069812	Nomascus leucogenys	99.02	0.00e+00	910.00
IUUC-Opr-070575	Ochotona princeps	93.63	1.00e-106	380.00
IUUC-Ont-072405	Oreochromis niloticus	52.51	6.00e-139	487.00
IUUC-Ocu-074358	Oryctolagus cuniculus	80.61	0.00e+00	768.00
IUUC-Ola-086403	Oryzias latipes	53.43	3.00e-141	494.00
IUUC-Oga-087986	Otolemur garnettii	93.53	0.00e+00	855.00
IUUC-Oar-089600	Ovis aries	92.16	0.00e+00	899.00
IUUC-Pan-092739	Papio anubis	99.61	0.00e+00	919.00
IUUC-Pma-094407	Petromyzon marinus	43.66	2.00e-112	399.00
IUUC-Pfo-097161	Poecilia formosa	53.32	1.00e-134	473.00
IUUC-Pab-098627	Pongo abelii	99.61	0.00e+00	895.00
IUUC-Pca-100641	Procavia capensis	92.03	0.00e+00	822.00
IUUC-Pva-102670	Pteropus vampyrus	91.76	0.00e+00	866.00
IUUC-Pte-104234	Pyrenophora teres	25.41	3.00e-12	66.20
IUUC-Rno-105504	Rattus norvegicus	90.78	0.00e+00	843.00
IUUC-Sha-107342	Sarcophilus harrisii	78.29	0.00e+00	770.00
IUUC-Sar-113425	Sorex araneus	87.67	7.00e-113	400.00
IUUC-Ssc-115904	Sus scrofa	93.64	8.00e-90	322.00
IUUC-Tru-118096	Takifugu rubripes	51.73	9.00e-139	486.00
IUUC-Tni-119873	Tetraodon nigroviridis	50.10	3.00e-139	488.00
IUUC-Tbe-127578	Tupaia belangeri	90.78	0.00e+00	693.00
IUUC-Ttr-129107	Tursiops truncatus	94.31	0.00e+00	857.00
IUUC-Vpa-130353	Vicugna pacos	95.14	1.00e-124	439.00
IUUC-Xtr-132168	Xenopus tropicalis	42.21	6.00e-94	337.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence