iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-017380

Ensembl Protein ID

Bra001426.1-P

UniProt Accession

M4CB47; M4CB47_BRARP

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra001426	Bra001426.1	Bra001426.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.60e-70	237.8	197	520
ULD/UDP/UBQ/UBQ_Other	4.30e-06	27.5	589	644

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEfl 96
           +GlkN+g+tCYmNS+L +L++ip +r+++ +     ++ ++++ p++++  +lq+lf +l ++++++v+++el+k++++    +++++q+D+qE+ 
   Q: 197  VGLKNQGATCYMNSLLETLYHIPYFRKAVYH-----MPTTENDAPTASIPLALQSLFYKL-QYNDTSVATKELTKSFGWDT--YDSFMQHDVQELN 284
           6******************************.....555555789***************.88999************877..67*********** PP
   S: 97   aflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLe 192
           ++l ++le+++                          k +  + +i++lF+g+  + i c + d +s+r+e+f+dl+l+v+g +     ++  +++
   Q: 285  RVLCEKLEDKM--------------------------KGTVVEGTIQKLFEGHQMNYIECINVDYKSTRKESFYDLQLDVKGCK-----DVYASFD 349
           ***********..........................7899*******************************************.....9****** PP
   S: 193  sftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls....pfctspeekqkekkkYeLiavv 284
           ++++ e+leg+nky+ e   ++q+a+k + +  +P+vL l+LkRf+++  ++   kin+++efpl+Ldl+    ++++ p+ ++++++ Y L++v+
   Q: 350  KYVEVERLEGDNKYHAEGH-DLQDAKKGVLFMDFPPVLQLQLKRFEYDFMRDIMVKINDRYEFPLQLDLDrengKYLS-PDADKSVRNLYTLHSVL 443
           ***************9996.59***********************************************965545555.5666678********** PP
   S: 285  vHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg.......................staYvlfYkr 337
           vHsG++++GHY+ay++   +++W++fdD++Vt+ + ++vlee+                        s+aY+l+Y r
   Q: 444  VHSGGVNGGHYYAYIRPtLSDQWYKFDDERVTKEDVNRVLEEQYggeeelpqnnpgfnnppfkftkySNAYMLVYIR 520
           ****************945677*******************7779******************************87 PP

ULD/UDP/UBQ/UBQ_Other

   S: 9    dgs.eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL....eddktLady 59
           d+  + +++++++++++ +Ke++ k++g+p+e qr +++ k +    +++++L ++
   Q: 589  DHEkVKSFRIEKQTPFLLFKEEVAKEFGVPVELQRFWIWAKRQnhtyRPNRPLLSH 644
           55559999*****************************9855544344888877766 PP

Organism

Brassica rapa

Protein Sequence
(Fasta)

MTMITPPPLD QQEDVEMLVP HSDVVEGPQP MEVAQPEAAA AVENPPVEEP PSVKFTWLIP 60
GFTRLNTRKH YSEVFVAGGY KWRVLIFPKG NNVDHLAMYL DVADAASLPY GWCRYSHFGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTATGA TAACCCCGCC GCCGCTCGAT GTAATCTCCG ATTAACCTCT TCGACATGAC 60
TATGATACCC CCGCCGCCGC TCGATGTAAT CTCCGATTAA CCTCATACTT CGTTTGTATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50144--MATH
PS00973--USP_2
PS50235--USP_3

Pfam

PF00917--MATH
PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg

SMART

SM00061--MATH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ani-009257	Aspergillus nidulans	29.91	2.00e-33	139.00
IUUC-Bci-013924	Botrytis cinerea	35.13	1.00e-166	580.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence