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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Spo-108049
UUCD1 version UUC-ScP-00057
Ensembl Protein ID SPBP22H7.07.1:pep
UniProt Accession O13615; PRP46_SCHPO
Genbank Protein ID AAG01399.1; BAA21403.1; CAC37375.1
Protein Name Pre-mRNA-splicing factor prp5; Complexed with cdc5 protein 1; Pre-mRNA-processing protein 5
Genbank Nucleotide ID AF251148; AB004535; CU329671
Gene Name prp5; cwf1; pi024; SPBP22H7.07
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SPBP22H7.07 SPBP22H7.07.1 SPBP22H7.07.1:pep
Annotation
mRNA Expression
GEO
Protein-protein Interaction
HINT
Protein 3D Structure
PDBMMDB
Post-translational Modifications (PTMs)
dbPAFdbPTM
Protein Expression/Proteomics
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.10e-40 133.1 161 197
UBD/Beta-Prp 3.40e-62 208.4 164 451
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH ++v+c++  ++   +++G++D tik+WDl +gvl
   Q: 161  GHLGWVRCVDVePGnQWFCTGAGDRTIKIWDLASGVL 197
           8***********77799****************9997 PP
   

   UBD/Beta-Prp
   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
           + ++cv++ p+++++ tg  d+tik+wd+ +g l  +l gh a+v+ +  sp+ ++l +++eD+++k wdl+t+k +++++gh + v++l++
   Q: 164  GWVRCVDVEPGNQWFCTGAGDRTIKIWDLASGVLKLTLTGHIATVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYALKL 255
           56899*************************************************************************************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngke 194
           +p+ d+lv++++d ++rvwd++t+q ++ +lsgh+++v +++v++++  +v+Gs D+t+rlWdl+ gk l+tlt  h++ v+ ls++++ + 
   Q: 256  HPTLDVLVTAGRDAVARVWDMRTRQNVH-VLSGHKSTVASLAVQEFDPQVVTGSMDSTIRLWDLAAGKTLTTLTH-HKKTVRALSLHPDEFT 345
           ****************************.*********************************************9.**************** PP
   S: 195  lvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn.....ssvisvav..lsfgdnv 279
           ++sgs d+ +k w + +g  +  ++gh++ v+ +     d+ + sg++ gs  +Wd +sg   + lq        +s   + +  ++ ++  
   Q: 346  FASGSSDN-IKHWKFPEGAFMGNFEGHNAIVNTLSIN-SDNVMFSGADNGSMCFWDWKSGHKYQELQSVVqpgslDSEAGIFAssFDKTGLR 435
           ******96.*************************999.9************************99998778888855555555345677999 PP
   S: 280  lvlgsedskvniwklk 295
           l+++++d++v+i+k+ 
   Q: 436  LITCEADKSVKIYKQV 451
           9************975 PP
   
Organism Schizosaccharomyces pombe
Functional Description
(View)

Functional Description


     Required for both cell cycle progression at G2/M and pre-mRNA splicing. Interacts genetically with the PRP4 kinase.
 Required for both cell cycle progression at G2/M and pre-mRNA splicing. Interacts genetically with the PRP4 kinase.
Protein Sequence
(Fasta)
MTEAKNISDD TDVLSLTTNS LRTSKTLFGA EFGSVTSFDD TVAQNLKRTY KEHLEYGSVL 60
GGTVGKRKNR HYEEDTIGSN ALTVRADSEN PSSQVITKFS DPNKKIAGQV SMQSLEKIKG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Spo-108049|E3,WD_repeat;UBD,Beta-Prp|Schizosaccharomyces pombe
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTCGCTAATG TTCGTGGATT ATGATGCTTC AAATAAGTCA GTCCAACTGC CATCTACCTA 60
CAAATCCTCT ACCAAAAATT TAACAGATTT ATGACAGAAG CAAAAAACAT ATCGGATGAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Spo-108049|E3,WD_repeat;UBD,Beta-Prp|Schizosaccharomyces pombe
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0747--Spliceosome
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005634--C:nucleus
GO:0071014--C:post-mRNA release spliceosomal complex
GO:0071011--C:precatalytic spliceosome
GO:0000974--C:Prp19 complex
GO:0005681--C:spliceosomal complex
GO:0045292--P:mRNA cis splicing, via spliceosome
KEGG spo:SPBP22H7.07
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000084 Aegilops tauschii 55.56 2.00e-127 446.00
IUUC-Aml-001605 Ailuropoda melanoleuca 62.61 1.00e-141 494.00
IUUC-Atr-002757 Amborella trichopoda 52.65 1.00e-129 454.00
IUUC-Apl-003198 Anas platyrhynchos 59.54 9.00e-142 494.00
IUUC-Aca-004683 Anolis carolinensis 49.51 4.00e-142 495.00
IUUC-Aly-005775 Arabidopsis lyrata 62.17 2.00e-132 463.00
IUUC-Ath-007460 Arabidopsis thaliana 61.88 1.00e-131 461.00
IUUC-Ago-007884 Ashbya gossypii 51.03 4.00e-121 426.00
IUUC-Acl-008153 Aspergillus clavatus 71.76 2.00e-149 520.00
IUUC-Afl-008384 Aspergillus flavus 68.58 4.00e-150 522.00
IUUC-Afu-009045 Aspergillus fumigatus 71.76 2.00e-149 520.00
IUUC-Ani-009229 Aspergillus nidulans 72.35 1.00e-148 517.00
IUUC-Ang-009812 Aspergillus niger 73.27 3.00e-140 488.00
IUUC-Aor-010059 Aspergillus oryzae 68.58 4.00e-150 522.00
IUUC-Ate-010351 Aspergillus terreus 71.47 2.00e-155 539.00
IUUC-Ame-011613 Astyanax mexicanus 42.00 8.00e-73 265.00
IUUC-Bgr-012042 Blumeria graminis 74.39 1.00e-155 540.00
IUUC-Bta-012406 Bos taurus 64.60 2.00e-141 493.00
IUUC-Bci-013760 Botrytis cinerea 75.29 9.00e-156 541.00
IUUC-Bdi-014776 Brachypodium distachyon 57.14 2.00e-129 453.00
IUUC-Bol-016189 Brassica oleracea 51.93 1.00e-131 461.00
IUUC-Bra-018044 Brassica rapa 51.93 2.00e-131 460.00
IUUC-Cel-018651 Caenorhabditis elegans 51.78 6.00e-141 491.00
IUUC-Cja-019974 Callithrix jacchus 64.31 3.00e-141 493.00
IUUC-Cfa-021085 Canis familiaris 62.61 1.00e-141 494.00
IUUC-Cpo-021458 Cavia porcellus 62.32 4.00e-141 492.00
IUUC-Cre-022880 Chlamydomonas reinhardtii 62.39 4.00e-133 465.00
IUUC-Csa-023883 Chlorocebus sabaeus 62.54 3.00e-141 493.00
IUUC-Cho-024623 Choloepus hoffmanni 66.36 8.00e-137 478.00
IUUC-Cin-025190 Ciona intestinalis 50.71 1.00e-138 484.00
IUUC-Csv-026367 Ciona savignyi 65.44 1.00e-138 484.00
IUUC-Cgl-026499 Colletotrichum gloeosporioides 73.29 1.00e-158 550.00
IUUC-Cne-027069 Cryptococcus neoformans 68.54 6.00e-140 488.00
IUUC-Cme-027233 Cyanidioschyzon merolae 29.46 1.00e-34 139.00
IUUC-Dre-028260 Danio rerio 65.24 1.00e-142 497.00
IUUC-Dno-029112 Dasypus novemcinctus 64.31 4.00e-141 492.00
IUUC-Dor-031118 Dipodomys ordii 63.72 2.00e-139 486.00
IUUC-Dse-031493 Dothistroma septosporum 69.62 9.00e-145 504.00
IUUC-Dme-032138 Drosophila melanogaster 66.36 6.00e-140 488.00
IUUC-Ete-032411 Echinops telfairi 44.42 1.00e-116 410.00
IUUC-Eca-033521 Equus caballus 64.01 1.00e-140 491.00
IUUC-Eeu-035249 Erinaceus europaeus 55.16 3.00e-112 396.00
IUUC-Fca-036358 Felis catus 62.32 6.00e-141 492.00
IUUC-Fal-036933 Ficedula albicollis 62.89 2.00e-141 493.00
IUUC-Fox-037713 Fusarium oxysporum 65.99 2.00e-158 550.00
IUUC-Fso-038380 Fusarium solani 74.85 9.00e-158 547.00
IUUC-Gmo-039133 Gadus morhua 64.84 3.00e-141 493.00
IUUC-Ggr-039915 Gaeumannomyces graminis 75.00 2.00e-148 516.00
IUUC-Gga-041176 Gallus gallus 63.74 4.00e-142 496.00
IUUC-Gac-042344 Gasterosteus aculeatus 64.83 1.00e-140 490.00
IUUC-Gma-042892 Glycine max 52.14 9.00e-133 464.00
IUUC-Ggo-044478 Gorilla gorilla 62.54 4.00e-141 492.00
IUUC-Hsa-046037 Homo sapiens 62.54 4.00e-141 492.00
IUUC-Hvu-047349 Hordeum vulgare 60.51 6.00e-131 458.00
IUUC-Itr-048390 Ictidomys tridecemlineatus 64.31 4.00e-141 492.00
IUUC-Kpa-049343 Komagataella pastoris 58.95 2.00e-125 439.00
IUUC-Lch-049830 Latimeria chalumnae 64.24 4.00e-142 496.00
IUUC-Lpe-051442 Leersia perrieri 56.81 4.00e-130 456.00
IUUC-Loc-051794 Lepisosteus oculatus 66.46 4.00e-137 479.00
IUUC-Lma-053137 Leptosphaeria maculans 59.08 1.00e-141 494.00
IUUC-Laf-053471 Loxodonta africana 64.31 3.00e-141 493.00
IUUC-Mcc-055627 Macaca mulatta 62.54 3.00e-141 493.00
IUUC-Meu-056148 Macropus eugenii 50.84 2.00e-136 476.00
IUUC-Mor-056960 Magnaporthe oryzae 73.87 4.00e-155 539.00
IUUC-Mtr-057816 Medicago truncatula 51.35 2.00e-131 460.00
IUUC-Mla-059031 Melampsora laricipopulina 63.71 6.00e-141 491.00
IUUC-Mga-059337 Meleagris gallopavo 63.74 7.00e-142 495.00
IUUC-Mvi-060217 Microbotryum violaceum 70.53 2.00e-142 496.00
IUUC-Mmr-061018 Microcebus murinus 62.54 4.00e-141 492.00
IUUC-Mdo-062863 Monodelphis domestica 66.15 3.00e-139 486.00
IUUC-Mmu-063988 Mus musculus 64.01 7.00e-140 488.00
IUUC-Mac-064459 Musa acuminata 63.21 2.00e-123 434.00
IUUC-Mpu-066559 Mustela putorius furo 62.61 1.00e-141 494.00
IUUC-Mlu-067361 Myotis lucifugus 64.31 6.00e-141 492.00
IUUC-Nfi-068492 Neosartorya fischeri 72.06 1.00e-149 520.00
IUUC-Ncr-068808 Neurospora crassa 72.35 3.00e-155 539.00
IUUC-Nle-069875 Nomascus leucogenys 62.54 4.00e-141 492.00
IUUC-Opr-070462 Ochotona princeps 66.17 8.00e-113 398.00
IUUC-Ont-071365 Oreochromis niloticus 65.31 1.00e-140 490.00
IUUC-Oan-072708 Ornithorhynchus anatinus 62.32 7.00e-141 491.00
IUUC-Ocu-074594 Oryctolagus cuniculus 64.31 5.00e-141 492.00
IUUC-Oba-075570 Oryza barthii 59.66 2.00e-129 453.00
IUUC-Obr-076366 Oryza brachyantha 65.25 6.00e-94 334.00
IUUC-Ogl-077153 Oryza glaberrima 59.38 3.00e-128 449.00
IUUC-Ogu-078540 Oryza glumaepatula 59.66 2.00e-129 453.00
IUUC-Oin-079612 Oryza indica 58.82 2.00e-127 447.00
IUUC-Olo-081077 Oryza longistaminata 58.82 2.00e-127 447.00
IUUC-Ome-081236 Oryza meridionalis 59.10 2.00e-127 447.00
IUUC-Oni-082499 Oryza nivara 59.66 2.00e-129 453.00
IUUC-Opu-083499 Oryza punctata 58.82 2.00e-127 446.00
IUUC-Oru-084276 Oryza rufipogon 59.66 2.00e-129 453.00
IUUC-Osa-085849 Oryza sativa 59.66 2.00e-129 453.00
IUUC-Ola-086655 Oryzias latipes 50.00 2.00e-140 490.00
IUUC-Olu-087637 Ostreococcus lucimarinus 63.53 1.00e-132 464.00
IUUC-Oga-087934 Otolemur garnettii 59.95 4.00e-142 495.00
IUUC-Oar-090185 Ovis aries 64.60 3.00e-141 493.00
IUUC-Ptr-091198 Pan troglodytes 62.54 4.00e-141 492.00
IUUC-Pan-092622 Papio anubis 62.54 3.00e-141 493.00
IUUC-Psi-093320 Pelodiscus sinensis 49.02 8.00e-142 494.00
IUUC-Pma-094638 Petromyzon marinus 63.56 4.00e-140 489.00
IUUC-Pno-094826 Phaeosphaeria nodorum 58.24 2.00e-120 423.00
IUUC-Ppa-095576 Physcomitrella patens 67.09 8.00e-130 454.00
IUUC-Pfo-096894 Poecilia formosa 65.89 2.00e-141 493.00
IUUC-Pab-098020 Pongo abelii 62.54 3.00e-141 493.00
IUUC-Pop-099180 Populus trichocarpa 49.25 2.00e-125 440.00
IUUC-Pca-100909 Procavia capensis 67.42 2.00e-113 400.00
IUUC-Ppe-101346 Prunus persica 50.00 3.00e-132 463.00
IUUC-Pva-102167 Pteropus vampyrus 52.97 9.00e-113 398.00
IUUC-Pgr-103516 Puccinia graminis 69.91 2.00e-139 487.00
IUUC-Ptt-103738 Puccinia triticina 68.48 2.00e-139 486.00
IUUC-Pte-104352 Pyrenophora teres 66.18 2.00e-147 513.00
IUUC-Pyt-104632 Pyrenophora triticirepentis 67.06 9.00e-149 518.00
IUUC-Rno-105291 Rattus norvegicus 63.72 7.00e-140 488.00
IUUC-Sce-106204 Saccharomyces cerevisiae 55.08 9.00e-119 418.00
IUUC-Sha-106943 Sarcophilus harrisii 48.62 6.00e-136 475.00
IUUC-Sja-107659 Schizosaccharomyces japonicus 73.96 0.00e+00 675.00
IUUC-Smo-109043 Selaginella moellendorffii 62.83 4.00e-133 465.00
IUUC-Sit-110431 Setaria italica 60.23 5.00e-131 458.00
IUUC-Sly-111391 Solanum lycopersicum 64.56 4.00e-126 442.00
IUUC-Stu-112364 Solanum tuberosum 57.24 5.00e-99 352.00
IUUC-Sar-113450 Sorex araneus 64.01 7.00e-140 488.00
IUUC-Sbi-113829 Sorghum bicolor 57.41 1.00e-129 454.00
IUUC-Sre-115153 Sporisorium reilianum 65.02 5.00e-130 456.00
IUUC-Ssc-116274 Sus scrofa 64.31 6.00e-141 492.00
IUUC-Tgu-117417 Taeniopygia guttata 62.89 2.00e-141 493.00
IUUC-Tru-117615 Takifugu rubripes 55.88 3.00e-134 469.00
IUUC-Tsy-119480 Tarsius syrichta 64.31 4.00e-141 492.00
IUUC-Tni-119847 Tetraodon nigroviridis 56.59 1.00e-140 490.00
IUUC-Tca-121287 Theobroma cacao 49.22 1.00e-127 447.00
IUUC-Tre-122010 Trichoderma reesei 74.62 1.00e-158 550.00
IUUC-Tvi-122475 Trichoderma virens 74.02 3.00e-158 549.00
IUUC-Tae-124397 Triticum aestivum 60.28 3.00e-131 459.00
IUUC-Tur-126116 Triticum urartu 49.72 3.00e-96 343.00
IUUC-Tme-126992 Tuber melanosporum 73.39 2.00e-159 553.00
IUUC-Tbe-127803 Tupaia belangeri 65.44 8.00e-111 391.00
IUUC-Ttr-128933 Tursiops truncatus 64.31 4.00e-141 492.00
IUUC-Uma-129447 Ustilago maydis 62.31 4.00e-126 442.00
IUUC-Vda-129780 Verticillium dahliae 68.77 2.00e-159 553.00
IUUC-Vpa-130557 Vicugna pacos 42.50 8.00e-46 176.00
IUUC-Vvi-130918 Vitis vinifera 50.23 2.00e-125 440.00
IUUC-Xtr-132409 Xenopus tropicalis 62.04 5.00e-140 489.00
IUUC-Xma-133420 Xiphophorus maculatus 65.60 1.00e-141 494.00
IUUC-Yli-134362 Yarrowia lipolytica 54.44 3.00e-140 489.00
IUUC-Zma-135804 Zea mays 57.70 4.00e-126 442.00
Created Date 25-Jun-2017

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