iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	dbPTM	UniProt
PHOSIDA	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/Alpha-Helix/CUE	CUE	18931041; 23993092

Organism

Saccharomyces cerevisiae

Functional Description
(View)

RNA polymerase II degradation factor recruits the ubiquitination machinery to the RNA polymerase II for polyubiquitination, removal and degradation, when RAD26 fails to efficiently displace stalled RNA polymerase II. Also involved in telomere length regulation.

Protein Sequence
(Fasta)

MSTQFRKSNH NSHSSKKLNP ALKSKIDTLT ELFPDWTSDD LIDIVQEYDD LETIIDKITS 60
GAVTRWDEVK KPAKKEKYEK KEQQHSYVPQ QHLPNPEDDI TYKSSNNSNS FTSTKHNSSN 120

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Nucleotide Sequence
(Fasta)

ATGTCTACAC AATTTAGGAA GTCTAATCAT AATAGTCATA GTAGTAAAAA ACTAAATCCT 60
GCGCTAAAGT CCAAAATAGA TACGCTTACA GAATTGTTCC CTGACTGGAC GAGTGATGAT 120

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Sequence Source

Ensembl

Keyword

KW-0158--Chromosome
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0238--DNA-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0779--Telomere
KW-0833--Ubl conjugation pathway

Interpro

IPR003892--CUE

PROSITE

PS51140--CUE

Pfam

PF02845--CUE

Gene Ontology

GO:0000781--C:chromosome, telomeric region
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0016567--P:protein ubiquitination
GO:0000723--P:telomere maintenance
GO:0006283--P:transcription-coupled nucleotide-excision repair
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

sce:YKL054C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007842	Ashbya gossypii	57.97	2.00e-21	95.50
IUUC-Acl-008346	Aspergillus clavatus	46.81	5.00e-08	51.60
IUUC-Afu-008947	Aspergillus fumigatus	46.67	3.00e-08	52.40
IUUC-Ani-009287	Aspergillus nidulans	48.89	7.00e-09	54.30
IUUC-Ang-009672	Aspergillus niger	47.62	3.00e-06	43.50
IUUC-Aor-010169	Aspergillus oryzae	51.11	2.00e-09	55.80
IUUC-Ate-010403	Aspergillus terreus	51.43	3.00e-06	45.40
IUUC-Bgr-012096	Blumeria graminis	39.13	2.00e-08	52.40
IUUC-Bci-013969	Botrytis cinerea	42.55	2.00e-09	56.20
IUUC-Cel-018295	Caenorhabditis elegans	44.44	2.50e-02	30.40
IUUC-Cgl-026768	Colletotrichum gloeosporioides	36.17	1.00e-04	36.20
IUUC-Cne-026987	Cryptococcus neoformans	38.46	3.20e-02	32.00
IUUC-Dse-031419	Dothistroma septosporum	36.17	4.00e-06	45.40
IUUC-Fox-038044	Fusarium oxysporum	32.61	1.00e-03	36.60
IUUC-Fso-038371	Fusarium solani	32.61	5.00e-05	41.60
IUUC-Ggr-040008	Gaeumannomyces graminis	34.04	2.00e-05	43.10
IUUC-Kpa-049227	Komagataella pastoris	51.11	2.00e-10	58.50
IUUC-Mor-057258	Magnaporthe oryzae	29.63	2.00e-04	39.70
IUUC-Mpo-057575	Magnaporthe poae	34.04	4.00e-05	41.60
IUUC-Mla-058869	Melampsora laricipopulina	39.53	2.00e-05	39.70
IUUC-Mvi-060545	Microbotryum violaceum	38.89	5.00e-06	44.70
IUUC-Nfi-068569	Neosartorya fischeri	48.89	1.00e-08	53.50
IUUC-Ncr-068873	Neurospora crassa	32.61	2.00e-05	42.70
IUUC-Pno-095140	Phaeosphaeria nodorum	43.75	4.00e-08	52.00
IUUC-Pgr-103269	Puccinia graminis	37.78	6.00e-05	41.60
IUUC-Ptt-103757	Puccinia triticina	40.00	1.50e-02	33.10
IUUC-Pte-104043	Pyrenophora teres	50.00	5.00e-10	58.20
IUUC-Pyt-104760	Pyrenophora triticirepentis	52.08	4.00e-10	58.50
IUUC-Sja-107853	Schizosaccharomyces japonicus	45.65	7.00e-08	50.80
IUUC-Spo-108061	Schizosaccharomyces pombe	48.94	6.00e-08	51.20
IUUC-Sre-115033	Sporisorium reilianum	31.91	4.00e-04	38.50
IUUC-Tre-121872	Trichoderma reesei	32.61	9.00e-05	40.40
IUUC-Tvi-122493	Trichoderma virens	30.43	2.00e-04	39.30
IUUC-Tme-127134	Tuber melanosporum	31.91	1.00e-04	40.40
IUUC-Uma-129410	Ustilago maydis	34.04	2.00e-04	39.70
IUUC-Vda-129677	Verticillium dahliae	33.33	1.50e-02	33.50
IUUC-Yli-134616	Yarrowia lipolytica	38.18	6.00e-02	30.80

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence