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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Dme-032214
Ensembl Protein ID FBpp0309831
UniProt Accession Q867Z4; A4UZC3; Q867F7; Q867K2; Q867T0; Q86BC3; Q8MKX6; Q8MZH5; LOLA4_DROME
Genbank Protein ID BAC67584.1; BAC67585.1; BAC67586.1; BAC67587.1; BAC67604.1; BAC67605.1; BAC67606.1; BAC67607.1; BAC67624.1; BAC67625.1; BAC67626.1; BAC67627.1; BAC67644.1; BAC67645.1; BAC67646.1; BAC67647.1; AAM68764.3; AAM68767.2; AAO41426.1; AAO41427.1; AAO41428.1; AAM27509.1
Protein Name Longitudinals lacking protein, isoforms F/I/K/T
Genbank Nucleotide ID AB107279; AB107280; AB107281; AB107282; AB107299; AB107300; AB107301; AB107302; AB107319; AB107320; AB107321; AB107322; AB107339; AB107340; AB107341; AB107342; AE013599; AE013599; AE013599; AE013599; AE013599; AY102680
Gene Name lola; CG12052
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0005630 FBtr0089362 FBpp0088396
FBgn0005630 FBtr0343132 FBpp0309831
FBgn0005630 FBtr0089351 FBpp0088385
FBgn0005630 FBtr0089356 FBpp0088390
FBgn0005630 FBtr0089343 FBpp0088377
FBgn0005630 FBtr0089344 FBpp0088378
FBgn0005630 FBtr0089364 FBpp0088950
FBgn0005630 FBtr0089352 FBpp0088386
FBgn0005630 FBtr0089342 FBpp0088376
FBgn0005630 FBtr0089355 FBpp0088389
FBgn0005630 FBtr0089353 FBpp0088387
FBgn0005630 FBtr0089357 FBpp0088391
FBgn0005630 FBtr0089365 FBpp0088951
FBgn0005630 FBtr0089361 FBpp0088395
FBgn0005630 FBtr0089348 FBpp0088382
FBgn0005630 FBtr0089366 FBpp0088948
FBgn0005630 FBtr0089346 FBpp0088380
FBgn0005630 FBtr0100286 FBpp0099680
FBgn0005630 FBtr0089363 FBpp0088949
FBgn0005630 FBtr0089360 FBpp0088394
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexPINAMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPHOSIDA
Protein Expression/Proteomics
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 1.60e-10 41.2 33 95
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           D++l  +g+  +ahk+vL+a+S++F  l++ + ++   ++   +kdv+++ +ra+++++Y g++++
   Q: 33   DCTLAAEGKFLKAHKVVLSACSPYFATLLQEQYDK---HPIFILKDVKYQELRAMMDYMYRGEVNI 95
           9****************************776655...6899999*****************9976 PP
   
Organism Drosophila melanogaster
Functional Description
(View)

Functional Description


     Putative transcription factor required for axon growth and guidance in the central and peripheral nervous systems. Repels CNS axons away from the midline by promoting the expression of the midline repellent sli and its receptor robo.
 Putative transcription factor required for axon growth and guidance in the central and peripheral nervous systems. Repels CNS axons away from the midline by promoting the expression of the midline repellent sli and its receptor robo.
Protein Sequence
(Fasta)
MDDDQQFCLR WNNHQSTLIS VFDTLLENET LVDCTLAAEG KFLKAHKVVL SACSPYFATL 60
LQEQYDKHPI FILKDVKYQE LRAMMDYMYR GEVNISQDQL AALLKAAESL QIKGLSDNRT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-032214|E3,BTB_Other|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTCAGTAAC AAACGGCAAC TCTCAGGAAT AAAATCGTCG TCGCTCCGCT CGTTAAATTC 60
TCGTTGCTTT TCCACCCACA TAAAAAATCA GGATAAATTG TTAGTAGTCT AAAAAACAGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-032214|E3,BTB_Other|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0221--Differentiation
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0524--Neurogenesis
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
PROSITE

PS50097--BTB
PS50157--ZINC_FINGER_C2H2_2
Pfam

PF00651--BTB
SMART

SM00225--BTB
SM00355--ZnF_C2H2
Gene Ontology

GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0019730--P:antimicrobial humoral response
GO:0007411--P:axon guidance
GO:0016199--P:axon midline choice point recognition
GO:0007409--P:axonogenesis
GO:0048854--P:brain morphogenesis
GO:0048813--P:dendrite morphogenesis
GO:0008406--P:gonad development
GO:0002121--P:inter-male aggressive behavior
GO:0035167--P:larval lymph gland hemopoiesis
GO:0007526--P:larval somatic muscle development
GO:0031987--P:locomotion involved in locomotory behavior
GO:0022008--P:neurogenesis
GO:0045476--P:nurse cell apoptotic process
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0007464--P:R3/R4 cell fate commitment
GO:0045467--P:R7 cell development
GO:0010906--P:regulation of glucose metabolic process
GO:0044719--P:regulation of imaginal disc-derived wing size
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006355--P:regulation of transcription, DNA-templated
GO:0001964--P:startle response
GO:0006351--P:transcription, DNA-templated
Orthology
iUUCD ID Species Identity E-value Score
Created Date 25-Jun-2017

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