iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-008857

Ensembl Protein ID

CADAFUAP00004632

UniProt Accession

Q4X1X5; Q4X1X5_ASPFU

Genbank Protein ID

EAL93140.1

Protein Name

Ubiquitin C-terminal hydrolase, putative

Genbank Nucleotide ID

AAHF01000001

Gene Name

AFUA_2G08440

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00004632	CADAFUAT00004632	CADAFUAP00004632

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-70	237.0	1617	1944

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaee.fsgyeqqD 91
           GlkNl NtCY+NS+L +L++  ++r+++l+     l+ ++ ++++++ll + +klf+ ++++  ++v+p+ l++ ++++ +e ++ + q D
   Q: 1617 GLKNLSNTCYLNSLLTQLFMNVQFRDFMLQ-----LHLSD-PDTSQRLLAETKKLFAYMQETWLRNVDPQGLVDNIRTYDNEpIDVTIQMD 1701
           9*****************************.....43333.58899********************************98888******** PP
   S: 92   aqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeet 182
           + Ef + l+d+ e ++                          +  + k+     ++gql +qik +ec ++s+r epf  ++++++g+   
   Q: 1702 VDEFYNLLFDRWEAQI--------------------------TGAEDKKKFRSFYGGQLVQQIKSKECPHISERLEPFSAIQCEIKGRA-- 1764
           ****************..........................566677778889***********************************.. PP
   S: 183  kkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts....pe 269
              sl+++L+++++ e ++g+nky+c++c ++++a+k+  lk++P+ Li+hLkRf f+  +++r+kin+++ fp+++d+spf ++    ++
   Q: 1765 ---SLEESLQAYVEGEIMQGDNKYSCTSCGRHVDAVKRACLKEVPDNLIFHLKRFDFDMITMMRSKINDEFRFPEHIDMSPFKVEylsdQN 1852
           ...9****************************************************************************77776333144 PP
   S: 270  ekqkekkkYeLiavvvHsGslssGHYvayvkn.....ekgkWllfdDskVtevkeeevleetg....................staYvlfY 335
           +++  ++ ++L++v+vHsG+++sGHY++y+++      +g+W++f+Ds V+  + +++  ++                     ++aY+lfY
   Q: 1853 SNV-PEDVFKLVGVLVHSGTAESGHYYSYIRErpnagGRGSWVEFNDSDVSRFDPSKIADQCFggyndsvhpanvnqvrfnkvWNAYMLFY 1942
           433.499*************************765555666*******************8779*************************** PP
   S: 336  kr 337
           +r
   Q: 1943 QR 1944
           98 PP

Organism

Aspergillus fumigatus

Protein Sequence
(Fasta)

MAAAPLDSSS TPPDAPQSTD STHPHGDFME DLDPQCTRKR PRLDSGSGAV ESLSIDEAAI 60
SRMSESTPAA PATPGTTDHD VPVSAAPASR VTINVKSPTS DTMATDSLNP TSEHPGAGPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGCTG CCCCGCTAGA TAGCTCTAGC ACCCCGCCCG ACGCTCCTCA ATCCACCGAT 60
TCGACGCATC CACACGGCGA CTTCATGGAA GATCTCGACC CCCAATGTAC CCGGAAACGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR021905--DUF3517
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF12030--DUF3517
PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

afm:AFUA_2G08440

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002257	Ailuropoda melanoleuca	27.02	2.00e-63	237.00
IUUC-Atr-002976	Amborella trichopoda	31.44	4.00e-33	135.00
IUUC-Apl-003284	Anas platyrhynchos	28.48	5.00e-65	243.00
IUUC-Aca-004415	Anolis carolinensis	27.84	2.00e-64	240.00
IUUC-Acl-008140	Aspergillus clavatus	73.92	0.00e+00	3720.00
IUUC-Afl-008381	Aspergillus flavus	65.59	0.00e+00	3299.00
IUUC-Ani-009257	Aspergillus nidulans	56.68	0.00e+00	2805.00
IUUC-Ang-009759	Aspergillus niger	61.64	0.00e+00	3109.00
IUUC-Aor-009931	Aspergillus oryzae	67.16	0.00e+00	3061.00
IUUC-Ate-010246	Aspergillus terreus	61.46	0.00e+00	3077.00
IUUC-Ame-011886	Astyanax mexicanus	32.61	1.00e-55	209.00
IUUC-Bgr-012195	Blumeria graminis	34.94	0.00e+00	674.00
IUUC-Bta-012989	Bos taurus	27.35	3.00e-64	240.00
IUUC-Bci-013798	Botrytis cinerea	31.28	0.00e+00	1025.00
IUUC-Cja-018955	Callithrix jacchus	29.88	5.00e-56	212.00
IUUC-Cfa-021214	Canis familiaris	27.35	4.00e-64	239.00
IUUC-Cpo-021912	Cavia porcellus	26.86	6.00e-64	238.00
IUUC-Csa-023658	Chlorocebus sabaeus	26.70	1.00e-63	238.00
IUUC-Cho-025074	Choloepus hoffmanni	28.23	2.00e-47	184.00
IUUC-Cin-025147	Ciona intestinalis	39.04	2.00e-42	163.00
IUUC-Csv-025956	Ciona savignyi	30.82	4.00e-58	219.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	31.24	0.00e+00	905.00
IUUC-Dre-027428	Danio rerio	27.24	2.00e-62	234.00
IUUC-Dno-029690	Dasypus novemcinctus	27.18	2.00e-63	237.00
IUUC-Dor-030817	Dipodomys ordii	33.86	1.00e-63	238.00
IUUC-Dse-031423	Dothistroma septosporum	25.49	2.00e-82	300.00
IUUC-Dme-032102	Drosophila melanogaster	29.48	2.00e-55	211.00
IUUC-Ete-032287	Echinops telfairi	26.61	9.00e-53	201.00
IUUC-Eca-033457	Equus caballus	27.35	1.00e-63	238.00
IUUC-Eeu-035178	Erinaceus europaeus	28.51	4.00e-45	176.00
IUUC-Fca-036213	Felis catus	27.35	3.00e-64	239.00
IUUC-Fal-037643	Ficedula albicollis	28.00	1.00e-64	241.00
IUUC-Fox-037971	Fusarium oxysporum	38.99	4.00e-157	548.00
IUUC-Fso-038108	Fusarium solani	30.25	0.00e+00	877.00
IUUC-Gmo-038587	Gadus morhua	32.51	3.00e-55	209.00
IUUC-Ggr-040075	Gaeumannomyces graminis	29.04	0.00e+00	886.00
IUUC-Gga-040511	Gallus gallus	28.64	7.00e-66	246.00
IUUC-Gac-042024	Gasterosteus aculeatus	28.04	2.00e-62	234.00
IUUC-Ggo-044924	Gorilla gorilla	27.21	2.00e-64	241.00
IUUC-Hsa-046913	Homo sapiens	27.21	5.00e-64	239.00
IUUC-Itr-048626	Ictidomys tridecemlineatus	26.86	3.00e-64	240.00
IUUC-Lch-049675	Latimeria chalumnae	33.73	4.00e-57	216.00
IUUC-Loc-052832	Lepisosteus oculatus	28.04	5.00e-63	236.00
IUUC-Lma-053130	Leptosphaeria maculans	29.85	0.00e+00	848.00
IUUC-Laf-054169	Loxodonta africana	26.86	3.00e-64	240.00
IUUC-Mcc-055217	Macaca mulatta	29.88	8.00e-56	212.00
IUUC-Meu-056659	Macropus eugenii	27.22	4.00e-42	166.00
IUUC-Mor-057152	Magnaporthe oryzae	30.88	0.00e+00	875.00
IUUC-Mpo-057310	Magnaporthe poae	28.96	0.00e+00	900.00
IUUC-Mga-059267	Meleagris gallopavo	29.88	2.00e-56	214.00
IUUC-Mmr-060780	Microcebus murinus	26.70	9.00e-64	238.00
IUUC-Mdo-062308	Monodelphis domestica	28.48	1.00e-64	241.00
IUUC-Mmu-063457	Mus musculus	26.70	6.00e-64	239.00
IUUC-Mpu-066917	Mustela putorius furo	27.35	4.00e-64	239.00
IUUC-Mlu-067696	Myotis lucifugus	26.86	3.00e-64	240.00
IUUC-Nfi-068259	Neosartorya fischeri	95.67	0.00e+00	4780.00
IUUC-Ncr-068911	Neurospora crassa	28.73	0.00e+00	908.00
IUUC-Nle-069586	Nomascus leucogenys	26.86	7.00e-64	239.00
IUUC-Opr-071031	Ochotona princeps	28.78	2.00e-47	184.00
IUUC-Ont-072396	Oreochromis niloticus	27.56	7.00e-62	232.00
IUUC-Oan-073147	Ornithorhynchus anatinus	28.32	1.00e-64	241.00
IUUC-Ocu-074324	Oryctolagus cuniculus	26.86	3.00e-64	240.00
IUUC-Olo-080364	Oryza longistaminata	28.38	4.00e-32	132.00
IUUC-Oni-083026	Oryza nivara	28.26	4.00e-32	132.00
IUUC-Oru-084797	Oryza rufipogon	28.26	4.00e-32	132.00
IUUC-Ola-086312	Oryzias latipes	27.56	1.00e-61	232.00
IUUC-Oga-088878	Otolemur garnettii	26.22	9.00e-65	242.00
IUUC-Oar-089919	Ovis aries	27.35	4.00e-64	239.00
IUUC-Ptr-090713	Pan troglodytes	27.21	1.00e-63	238.00
IUUC-Pan-091957	Papio anubis	26.70	8.00e-64	238.00
IUUC-Psi-093240	Pelodiscus sinensis	27.68	3.00e-64	240.00
IUUC-Pma-094469	Petromyzon marinus	25.94	2.00e-62	234.00
IUUC-Pno-095059	Phaeosphaeria nodorum	31.12	7.00e-153	534.00
IUUC-Pfo-097159	Poecilia formosa	27.72	1.00e-62	234.00
IUUC-Pab-098003	Pongo abelii	27.05	1.00e-62	235.00
IUUC-Pca-100799	Procavia capensis	26.70	3.00e-56	214.00
IUUC-Pva-103226	Pteropus vampyrus	26.86	3.00e-64	240.00
IUUC-Pte-104235	Pyrenophora teres	28.61	0.00e+00	909.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	32.01	1.00e-174	605.00
IUUC-Rno-105389	Rattus norvegicus	26.41	5.00e-64	239.00
IUUC-Sha-106979	Sarcophilus harrisii	28.48	2.00e-64	241.00
IUUC-Smo-109204	Selaginella moellendorffii	28.80	6.00e-70	258.00
IUUC-Sar-113729	Sorex araneus	26.37	3.00e-53	203.00
IUUC-Ssc-115815	Sus scrofa	26.70	1.00e-63	238.00
IUUC-Tgu-117470	Taeniopygia guttata	28.48	8.00e-65	242.00
IUUC-Tru-118543	Takifugu rubripes	27.24	2.00e-61	231.00
IUUC-Tsy-119165	Tarsius syrichta	28.66	3.00e-48	187.00
IUUC-Tni-119923	Tetraodon nigroviridis	28.27	2.00e-53	204.00
IUUC-Tre-122057	Trichoderma reesei	30.21	0.00e+00	850.00
IUUC-Tvi-122570	Trichoderma virens	28.71	0.00e+00	884.00
IUUC-Tme-127154	Tuber melanosporum	35.68	1.00e-177	615.00
IUUC-Tbe-127801	Tupaia belangeri	34.28	1.00e-54	208.00
IUUC-Ttr-129262	Tursiops truncatus	33.60	8.00e-63	235.00
IUUC-Vda-129686	Verticillium dahliae	36.20	5.00e-148	518.00
IUUC-Vpa-130484	Vicugna pacos	26.86	3.00e-64	240.00
IUUC-Xtr-131769	Xenopus tropicalis	27.67	2.00e-64	241.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence