iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062129

Ensembl Protein ID

ENSMODP00000015056.3

UniProt Accession

F7AM83; F7AM83_MONDO

Protein Name

Uncharacterized protein

Gene Name

PIK3R4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000012017.3	ENSMODT00000015334.3	ENSMODP00000015056.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-18	64.7	973	1002

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H++ v+ ++  ++  l++++s+Dgt+k+W+
   Q: 973  HKSAVNRIRVsDEhSLFATCSNDGTVKIWN 1002
           9999999999544788*************9 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MILNMGGFWG DPIFKVARAK HREGLVVVKV FAIQDPTLPL TSYKQELEEL KIRLNSAQNC 60
LPFQRATEKT SEKAALLFRQ YVRDNLYDRI STRPFLNNIE KRWIAFQILT AVDQAHKSGV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATCTTCTC TTGACGATAT TGACAGGGAT TCTGTCATTA TGGGAAACCA GCTGGCTGGC 60
ATTGCCCCCT CCCAGATCCT TTCTGTGGAC AGCTATTTTT CAGACATCCA TGATTTTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR021133--HEAT_type_2
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50077--HEAT_REPEAT
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00069--Pkinase
PF00400--WD40

SMART

SM00220--S_TKc
SM00320--WD40

Gene Ontology

GO:0005930--C:axoneme
GO:0005770--C:late endosome
GO:0015630--C:microtubule cytoskeleton
GO:0005643--C:nuclear pore
GO:0071561--C:nucleus-vacuole junction
GO:0034271--C:phosphatidylinositol 3-kinase complex, class III, type I
GO:0034272--C:phosphatidylinositol 3-kinase complex, class III, type II
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0042149--P:cellular response to glucose starvation
GO:0045324--P:late endosome to vacuole transport
GO:0016236--P:macroautophagy
GO:0030242--P:pexophagy
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:0006468--P:protein phosphorylation
GO:0006623--P:protein targeting to vacuole
GO:0032801--P:receptor catabolic process
GO:0032465--P:regulation of cytokinesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000213	Aegilops tauschii	31.47	6.00e-44	173.00
IUUC-Aml-001659	Ailuropoda melanoleuca	93.75	0.00e+00	2528.00
IUUC-Atr-002968	Amborella trichopoda	40.70	2.00e-43	171.00
IUUC-Apl-003418	Anas platyrhynchos	92.77	0.00e+00	2571.00
IUUC-Aca-004344	Anolis carolinensis	92.19	0.00e+00	2296.00
IUUC-Aly-006107	Arabidopsis lyrata	48.18	9.00e-67	249.00
IUUC-Ath-007260	Arabidopsis thaliana	48.51	1.00e-67	251.00
IUUC-Ago-007721	Ashbya gossypii	24.25	4.00e-54	207.00
IUUC-Acl-008378	Aspergillus clavatus	37.21	3.00e-146	513.00
IUUC-Afl-008632	Aspergillus flavus	35.78	9.00e-139	488.00
IUUC-Afu-009020	Aspergillus fumigatus	36.70	7.00e-140	492.00
IUUC-Ani-009204	Aspergillus nidulans	35.39	3.00e-130	460.00
IUUC-Ang-009811	Aspergillus niger	35.25	4.00e-137	483.00
IUUC-Aor-010168	Aspergillus oryzae	35.78	9.00e-139	488.00
IUUC-Ate-010556	Aspergillus terreus	35.72	3.00e-139	490.00
IUUC-Ame-011955	Astyanax mexicanus	81.37	0.00e+00	1783.00
IUUC-Bgr-012050	Blumeria graminis	36.19	1.00e-136	481.00
IUUC-Bta-012432	Bos taurus	92.84	0.00e+00	2554.00
IUUC-Bci-013846	Botrytis cinerea	33.97	7.00e-140	492.00
IUUC-Bdi-015072	Brachypodium distachyon	43.93	1.00e-64	242.00
IUUC-Bol-015314	Brassica oleracea	48.51	1.00e-67	252.00
IUUC-Bra-017476	Brassica rapa	48.51	1.00e-67	252.00
IUUC-Cel-018550	Caenorhabditis elegans	30.45	2.00e-75	278.00
IUUC-Cja-019538	Callithrix jacchus	93.67	0.00e+00	2566.00
IUUC-Cfa-020483	Canis familiaris	93.44	0.00e+00	2537.00
IUUC-Cpo-021392	Cavia porcellus	93.22	0.00e+00	2554.00
IUUC-Csa-024112	Chlorocebus sabaeus	93.90	0.00e+00	2573.00
IUUC-Cho-025015	Choloepus hoffmanni	86.00	0.00e+00	839.00
IUUC-Cin-025209	Ciona intestinalis	41.29	0.00e+00	1037.00
IUUC-Csv-026334	Ciona savignyi	41.30	0.00e+00	845.00
IUUC-Cgl-026447	Colletotrichum gloeosporioides	35.81	8.00e-139	489.00
IUUC-Cne-026999	Cryptococcus neoformans	39.65	3.00e-109	390.00
IUUC-Dre-028662	Danio rerio	82.01	0.00e+00	2265.00
IUUC-Dno-029545	Dasypus novemcinctus	91.64	0.00e+00	2491.00
IUUC-Dor-030941	Dipodomys ordii	68.78	0.00e+00	642.00
IUUC-Dse-031455	Dothistroma septosporum	35.94	2.00e-132	468.00
IUUC-Dme-031726	Drosophila melanogaster	39.75	0.00e+00	951.00
IUUC-Ete-033147	Echinops telfairi	90.72	0.00e+00	974.00
IUUC-Eca-034025	Equus caballus	94.05	0.00e+00	2571.00
IUUC-Eeu-034480	Erinaceus europaeus	86.16	0.00e+00	1390.00
IUUC-Fca-035741	Felis catus	93.22	0.00e+00	2527.00
IUUC-Fal-037666	Ficedula albicollis	91.64	0.00e+00	2540.00
IUUC-Fox-037818	Fusarium oxysporum	34.75	2.00e-124	440.00
IUUC-Fso-038086	Fusarium solani	35.06	3.00e-128	453.00
IUUC-Gmo-038804	Gadus morhua	81.46	0.00e+00	743.00
IUUC-Ggr-039800	Gaeumannomyces graminis	35.10	4.00e-132	466.00
IUUC-Gga-041251	Gallus gallus	92.43	0.00e+00	2062.00
IUUC-Gac-042376	Gasterosteus aculeatus	78.69	0.00e+00	2181.00
IUUC-Gma-044095	Glycine max	46.00	6.00e-71	263.00
IUUC-Ggo-044506	Gorilla gorilla	93.45	0.00e+00	2554.00
IUUC-Hsa-045871	Homo sapiens	93.82	0.00e+00	2566.00
IUUC-Hvu-047648	Hordeum vulgare	32.26	4.00e-46	180.00
IUUC-Itr-048082	Ictidomys tridecemlineatus	95.06	0.00e+00	1096.00
IUUC-Kpa-049390	Komagataella pastoris	32.73	4.00e-119	423.00
IUUC-Lch-050284	Latimeria chalumnae	86.78	0.00e+00	2316.00
IUUC-Lpe-050880	Leersia perrieri	42.59	5.00e-63	236.00
IUUC-Loc-052815	Lepisosteus oculatus	82.52	0.00e+00	2269.00
IUUC-Lma-053324	Leptosphaeria maculans	35.67	4.00e-139	489.00
IUUC-Laf-054204	Loxodonta africana	82.10	0.00e+00	2161.00
IUUC-Mcc-054612	Macaca mulatta	93.90	0.00e+00	2569.00
IUUC-Meu-056227	Macropus eugenii	93.54	0.00e+00	918.00
IUUC-Mor-057094	Magnaporthe oryzae	36.16	2.00e-132	467.00
IUUC-Mtr-058550	Medicago truncatula	44.48	7.00e-70	259.00
IUUC-Mla-058893	Melampsora laricipopulina	35.12	1.00e-127	451.00
IUUC-Mga-059474	Meleagris gallopavo	92.14	0.00e+00	2484.00
IUUC-Mvi-060227	Microbotryum violaceum	44.34	1.00e-76	281.00
IUUC-Mmr-061543	Microcebus murinus	86.13	0.00e+00	2277.00
IUUC-Mmu-064381	Mus musculus	91.79	0.00e+00	2515.00
IUUC-Mac-064455	Musa acuminata	38.61	7.00e-120	425.00
IUUC-Mpu-066151	Mustela putorius furo	94.42	0.00e+00	872.00
IUUC-Mlu-067824	Myotis lucifugus	93.97	0.00e+00	2571.00
IUUC-Nfi-068241	Neosartorya fischeri	37.51	8.00e-143	502.00
IUUC-Ncr-068964	Neurospora crassa	36.33	7.00e-138	485.00
IUUC-Nle-069152	Nomascus leucogenys	93.90	0.00e+00	2569.00
IUUC-Opr-070870	Ochotona princeps	82.32	0.00e+00	1337.00
IUUC-Ont-071293	Oreochromis niloticus	80.70	0.00e+00	2236.00
IUUC-Oan-072852	Ornithorhynchus anatinus	89.54	0.00e+00	2433.00
IUUC-Ocu-074727	Oryctolagus cuniculus	93.59	0.00e+00	2521.00
IUUC-Oba-075932	Oryza barthii	39.20	2.00e-61	231.00
IUUC-Obr-076424	Oryza brachyantha	46.48	4.00e-62	234.00
IUUC-Ogl-077491	Oryza glaberrima	39.20	2.00e-61	231.00
IUUC-Ogu-078933	Oryza glumaepatula	48.07	5.00e-65	243.00
IUUC-Oin-079604	Oryza indica	43.75	5.00e-67	249.00
IUUC-Olo-080850	Oryza longistaminata	35.67	1.00e-112	401.00
IUUC-Ome-081860	Oryza meridionalis	43.75	4.00e-67	250.00
IUUC-Oni-082895	Oryza nivara	39.20	3.00e-61	231.00
IUUC-Opu-083741	Oryza punctata	43.75	3.00e-66	247.00
IUUC-Oru-084616	Oryza rufipogon	38.89	6.00e-61	230.00
IUUC-Osa-085941	Oryza sativa	28.27	4.00e-36	145.00
IUUC-Ola-087357	Oryzias latipes	84.78	1.00e-139	488.00
IUUC-Olu-087659	Ostreococcus lucimarinus	31.36	2.00e-91	331.00
IUUC-Oga-088555	Otolemur garnettii	93.75	0.00e+00	2538.00
IUUC-Oar-089304	Ovis aries	93.48	0.00e+00	1221.00
IUUC-Ptr-091140	Pan troglodytes	93.90	0.00e+00	2568.00
IUUC-Pan-092413	Papio anubis	93.59	0.00e+00	2457.00
IUUC-Psi-093210	Pelodiscus sinensis	92.99	0.00e+00	2570.00
IUUC-Pma-094674	Petromyzon marinus	56.43	0.00e+00	724.00
IUUC-Pno-094969	Phaeosphaeria nodorum	31.25	1.00e-139	491.00
IUUC-Ppa-096017	Physcomitrella patens	26.49	4.00e-80	294.00
IUUC-Pfo-096077	Poecilia formosa	80.09	0.00e+00	2189.00
IUUC-Pab-098269	Pongo abelii	92.84	0.00e+00	2545.00
IUUC-Pop-100052	Populus trichocarpa	44.86	8.00e-62	233.00
IUUC-Pca-100377	Procavia capensis	88.44	0.00e+00	2306.00
IUUC-Ppe-101445	Prunus persica	44.74	1.00e-69	258.00
IUUC-Pva-102198	Pteropus vampyrus	93.26	0.00e+00	1649.00
IUUC-Pgr-103544	Puccinia graminis	48.14	8.00e-77	283.00
IUUC-Ptt-103964	Puccinia triticina	47.46	5.00e-73	270.00
IUUC-Pte-104196	Pyrenophora teres	35.97	6.00e-134	472.00
IUUC-Pyt-104544	Pyrenophora triticirepentis	36.09	7.00e-133	468.00
IUUC-Rno-105256	Rattus norvegicus	91.79	0.00e+00	2513.00
IUUC-Sce-106295	Saccharomyces cerevisiae	40.40	5.00e-65	243.00
IUUC-Sha-107597	Sarcophilus harrisii	97.51	0.00e+00	2635.00
IUUC-Sja-107781	Schizosaccharomyces japonicus	32.65	2.00e-96	348.00
IUUC-Spo-108031	Schizosaccharomyces pombe	45.36	4.00e-68	254.00
IUUC-Ssl-108579	Sclerotinia sclerotiorum	36.00	3.00e-133	470.00
IUUC-Smo-108679	Selaginella moellendorffii	46.25	3.00e-77	284.00
IUUC-Sit-110765	Setaria italica	42.28	2.00e-62	234.00
IUUC-Sly-111527	Solanum lycopersicum	46.30	3.00e-70	260.00
IUUC-Stu-112899	Solanum tuberosum	45.68	1.00e-69	258.00
IUUC-Sar-112986	Sorex araneus	93.07	0.00e+00	2540.00
IUUC-Sbi-114604	Sorghum bicolor	42.90	4.00e-66	247.00
IUUC-Sre-115191	Sporisorium reilianum	36.24	3.00e-63	238.00
IUUC-Ssc-115440	Sus scrofa	92.02	0.00e+00	2506.00
IUUC-Tgu-116633	Taeniopygia guttata	92.01	0.00e+00	2548.00
IUUC-Tru-118439	Takifugu rubripes	78.76	0.00e+00	2189.00
IUUC-Tsy-119472	Tarsius syrichta	85.97	0.00e+00	1374.00
IUUC-Tni-119808	Tetraodon nigroviridis	73.93	0.00e+00	1986.00
IUUC-Tca-121648	Theobroma cacao	49.18	2.00e-70	261.00
IUUC-Tre-122161	Trichoderma reesei	34.49	4.00e-119	423.00
IUUC-Tvi-122575	Trichoderma virens	33.86	7.00e-112	399.00
IUUC-Tae-123381	Triticum aestivum	44.86	6.00e-66	246.00
IUUC-Tur-126291	Triticum urartu	45.17	1.00e-65	245.00
IUUC-Tme-126979	Tuber melanosporum	36.85	3.00e-146	513.00
IUUC-Tbe-127576	Tupaia belangeri	78.82	0.00e+00	902.00
IUUC-Ttr-129106	Tursiops truncatus	94.88	0.00e+00	1202.00
IUUC-Uma-129633	Ustilago maydis	41.90	1.00e-69	259.00
IUUC-Vda-130001	Verticillium dahliae	46.44	3.00e-73	271.00
IUUC-Vpa-130733	Vicugna pacos	85.33	0.00e+00	1249.00
IUUC-Vvi-131318	Vitis vinifera	43.80	3.00e-68	254.00
IUUC-Xtr-131908	Xenopus tropicalis	86.87	0.00e+00	2412.00
IUUC-Xma-133331	Xiphophorus maculatus	80.24	0.00e+00	2202.00
IUUC-Yli-134651	Yarrowia lipolytica	38.01	1.00e-116	414.00
IUUC-Zma-135850	Zea mays	42.01	2.00e-65	244.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence