iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071725

Ensembl Protein ID

ENSONIP00000023448.1

UniProt Accession

I3KQQ3; I3KQQ3_ORENI

Genbank Protein ID

ENSONIP00000023448

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01030719

Gene Name

fzr1b; LOC100705088

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000018629.1	ENSONIT00000023469.1	ENSONIP00000023448.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-27	93.6	305	340
E3 adaptor/Cullin RING/APC_C/CDC20	2.20e-143	477.5	170	472

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gH  +v++l++ +d  +l+sG++D+++ vW+ ++  
   Q: 305  GHRQEVCGLKWsPDhQHLASGGNDNKLLVWNSSSLL 340
           8***********999***************976655 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWs+ n l+v+Lg++vylwsa+t++v++l+dl  ++d+vtsv w e+g+l+avGt+kg v+++D++  +k
   Q: 170  PFKVLDAPELQDDFYLNLVDWSAGNLLSVGLGACVYLWSACTSQVTRLCDLsVDGDSVTSVCWNERGSLVAVGTHKGYVQVWDAAGGRK 258
           689************************************************999*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfke 177
           + +l+ghsarvgaL+Wn e+lssGsrd+ il+rdvr++    ++lq+h+qevCGlkw+ d+++LasGGnDn++ vw++ss  P++++++
   Q: 259  LTSLEGHSARVGALAWNGEQLSSGSRDRVILQRDVRTPPSAERRLQGHRQEVCGLKWSPDHQHLASGGNDNKLLVWNSSSLLPVQQYSD 347
           ***************************************************************************************** PP
   S: 178  hkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgh 266
           h aavkaiawsP+q++lLasGGGtaDrc++fwntltg+ l++ dtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl++va+l+gh
   Q: 348  HLAAVKAIAWSPHQHGLLASGGGTADRCLRFWNTLTGQALQSTDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGH 436
           ***************************************************************************************** PP
   S: 267  eaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           ++Rvl+la+spdgeaivt+agDetlrfw++f+k++ 
   Q: 437  SYRVLYLAVSPDGEAIVTGAGDETLRFWNVFSKTRC 472
           ********************************9875 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MDQEYERRLL RQINHQNLPA EARLTKCLSA TCSPVSVKSG DRFIPTRAGS NWSINFHYAN 60
ENCRSPSQNH KAKDATSDSS KDAVAYAALL RNELLGAGIE TVPDPHTEDR RHAVLSQDSH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACATGGGGAT CCACTGCGGA TTTCCTTACC GGGAGGGAGC GGAGGTTTAA AGGGGGGCGG 60
GGAGAGCAGC AGAGGGGGCT CGCTGCTCGT CATCCCCGAA GAAATGGACC AAGAGTACGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005442	Arabidopsis lyrata	55.51	2.00e-139	489.00
IUUC-Ame-011773	Astyanax mexicanus	92.61	0.00e+00	934.00
IUUC-Bol-016301	Brassica oleracea	56.57	2.00e-139	488.00
IUUC-Bra-017453	Brassica rapa	56.57	2.00e-139	489.00
IUUC-Dre-027860	Danio rerio	93.02	0.00e+00	940.00
IUUC-Fox-037814	Fusarium oxysporum	64.17	9.00e-124	436.00
IUUC-Gmo-039431	Gadus morhua	87.89	0.00e+00	892.00
IUUC-Gac-041566	Gasterosteus aculeatus	96.10	0.00e+00	931.00
IUUC-Loc-052240	Lepisosteus oculatus	86.65	0.00e+00	875.00
IUUC-Ola-086983	Oryzias latipes	95.33	0.00e+00	964.00
IUUC-Pfo-096991	Poecilia formosa	94.46	0.00e+00	915.00
IUUC-Sit-110550	Setaria italica	52.97	1.00e-127	449.00
IUUC-Sbi-114386	Sorghum bicolor	52.95	1.00e-124	440.00
IUUC-Tru-118528	Takifugu rubripes	94.32	0.00e+00	914.00
IUUC-Tni-120312	Tetraodon nigroviridis	94.88	0.00e+00	912.00
IUUC-Tae-123028	Triticum aestivum	52.83	1.00e-126	446.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence