iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Post-translational Modifications (PTMs)
dbPPT	dbPTM	UniProt
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-22	79.1	452	484
UBD/Beta-Prp	6.10e-46	157.8	410	677

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tl.lvsGsdDgtikvWDl 30
           H + v++laf  ++  + +v+++dD+ ikvWDl
   Q: 452  HVGCVNDLAFahPNkQMcVVTCGDDKLIKVWDL 484
           9999********776554799***********7 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgk..ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
             +t v++spd++ll ++++ + i v+ ++  +l + l    h + v+++ f +  k    vt+++D++ikvwdls    + t++ghe+ v+s+  ++
   Q: 410  ISVTRVAWSPDGNLLGVSFTKHLIHVYAYQGSDLRQHLeiDAHVGCVNDLAFAHPNKqmCVVTCGDDKLIKVWDLSGK-KLFTFEGHEAPVYSICPHQ 506
           345667778888888888888888888888888765554467777788888877666677788888888888888754.4557888888888887777 PP
   S: 105  ..sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGsl....DrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelv 196
             + +++ s+  d  i+ w  ++     + +++  ++ +++ ++ dg+ l+s+++    D+++  W+ + g l rt  g  ++s   ++fd ++++++
   Q: 507  keNIQFIFSTALDGKIKAWLYDNVGSRVDYDAPG-QWCTTMLYSADGSRLFSCGTskegDSFLVEWNESEGALKRTYLGFRKKSAGVVQFDTTRNRFL 603
           6555888888888888887766655555455444.477777777777777777653444666777777***********9****************** PP
   S: 197  sgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriW.dlrsgdllktlqlhn..s 265
           ++++d+++k+w++ +++   v++ +g   n  ++rf +++++l+++++D+  +i  +++   +l++++ +    
   Q: 604  AVGEDNQIKFWNMDNTNLltVVEAEGGLPNLPRLRFNKDGNLLAVTTADNGFKILaNTDGLRTLRAFEARSfeA 677
           **************88773366666666788899999****************966777777777777766552 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Transcriptional corepressor. Negative regulator of jasmonate responses (By similarity).

Protein Sequence
(Fasta)

MSSLSRELVF LILQFLDEEK FKESVHKLEQ ESGFFFNIKY FEEKALAGEW DEVEKYLSGF 60
TKVDDNRYSM KIFFEIRKQK YLEALDRNDR AKAVEILAKD LKVFATFNEE LYKEITQLLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCATCTCTG GGGTCAGCTT TTTCTTAATG TTCGCTTTGC GACGCGAGGA AATGCAACCT 60
TGAAACCCTA GAAAACTCAT TCTCAACTAC GACTAAATCG ATTTCGCAAA CTTTGACCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1184--Jasmonic acid signaling pathway
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR006595--CTLH_C
IPR006594--LisH
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50897--CTLH
PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00668--CTLH
SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0010072--P:primary shoot apical meristem specification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

ath:AT3G16830

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005503	Arabidopsis lyrata	97.52	0.00e+00	2194.00
IUUC-Bdi-014677	Brachypodium distachyon	70.33	0.00e+00	1581.00
IUUC-Bol-016487	Brassica oleracea	93.49	0.00e+00	2075.00
IUUC-Bra-016798	Brassica rapa	93.31	0.00e+00	2058.00
IUUC-Hvu-047370	Hordeum vulgare	70.03	0.00e+00	1600.00
IUUC-Lpe-050951	Leersia perrieri	69.32	0.00e+00	1525.00
IUUC-Mtr-057839	Medicago truncatula	74.55	0.00e+00	1699.00
IUUC-Mac-064999	Musa acuminata	66.83	0.00e+00	1568.00
IUUC-Oba-075415	Oryza barthii	70.68	0.00e+00	1600.00
IUUC-Obr-076726	Oryza brachyantha	70.67	0.00e+00	1620.00
IUUC-Ogl-077810	Oryza glaberrima	70.68	0.00e+00	1600.00
IUUC-Ogu-078090	Oryza glumaepatula	70.68	0.00e+00	1600.00
IUUC-Oin-080158	Oryza indica	70.07	0.00e+00	1596.00
IUUC-Olo-080271	Oryza longistaminata	69.46	0.00e+00	1559.00
IUUC-Ome-081965	Oryza meridionalis	70.51	0.00e+00	1593.00
IUUC-Oni-082421	Oryza nivara	70.59	0.00e+00	1601.00
IUUC-Opu-083912	Oryza punctata	70.59	0.00e+00	1601.00
IUUC-Oru-085201	Oryza rufipogon	70.68	0.00e+00	1600.00
IUUC-Osa-086161	Oryza sativa	70.68	0.00e+00	1600.00
IUUC-Ppe-101491	Prunus persica	76.81	0.00e+00	1788.00
IUUC-Sit-110487	Setaria italica	71.40	0.00e+00	1590.00
IUUC-Sbi-113873	Sorghum bicolor	71.12	0.00e+00	1586.00
IUUC-Tca-121579	Theobroma cacao	75.89	0.00e+00	1696.00
IUUC-Tae-125707	Triticum aestivum	69.88	0.00e+00	1587.00
IUUC-Tur-126477	Triticum urartu	66.03	0.00e+00	1559.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence