iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055037

Ensembl Protein ID

ENSMMUP00000006207.3

UniProt Accession

F6RUM7; F6RUM7_MACMU

Genbank Protein ID

ENSMMUP00000006207

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03036681

Gene Name

WDR36

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000004670.3	ENSMMUT00000006598.3	ENSMMUP00000006207.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-21	76.2	612	648
UBD/Beta-Prp	2.10e-51	176.0	282	572

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ ++++af +d + l+s++ D++i+ WDl +g l
   Q: 612  GHQGQINDMAFsPDgRWLISAAMDCSIRTWDLPSGCL 648
           8***********99999***************99976 PP

UBD/Beta-Prp

   S: 11   svitcvkf.spdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvw....dlstgkcvhtlkgh 93
           ++it++ f +++ +++a+gs  g i +wd++++kl+ ++   h+ +++ ++f +++++lvt + D+++++w    +   g  ++   gh
   Q: 282  GPITSISFrTDGHPVMAAGSPCGHIGLWDLEDKKLINQMrNAHSTAIAGLTFLHREPLLVTNGADNALRIWifdgPTGEGRLLRFRMGH 370
           799*****9999***************************99******************************7765555899999999** PP
   S: 94   edsvlslsfsp.sgdklvsGshdrtirvwdletgqclee..........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..... 166
           ++ ++s++++  +g+ ++s+s+d t++ + + +++  ++          ++++  + +++v+++p +   +++   r    Wd      
   Q: 371  SAPLTSIRYYGqNGQQILSASQDGTLQSFSTVHEKFNKSlghglinkkrVKRKGLQNTMSVRLPPIT--KFAAEEARESD-WDGiiach 456
           *********99788**************999998888889999999999444444455555555522..22222222222.33333332 PP
   S: 167  ...........ktgkllrtl...tgghtdsvysls..fdsngkelvsgsldgtvklwdlq....tgecvrtlnghtdnvksvrfspnde 235
                      +  ++   +   ++ ++d+++ ++  ++s g++ v g   gtv ++++q    +g    + ++h+  v+ v+++  ++
   Q: 457  qgklscstwnyQKSTIGAYFlkpKEMKKDDITATAvdITSCGNFAVIGLSSGTVDVYNMQsgihRG-SFGKDQAHKGSVRGVAVDGLNQ 544
           222222222215555555558886667888877773355555******************555322.3777789*************** PP
   S: 236  rlvsgssDgsiriWdlrsgdllktlqlh 263
           + v+++s+g +++W+ +++ l+++++l+
   Q: 545  LTVTTGSEGLLKFWNFKNKILIHSVSLS 572
           ******************9999998875 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MCCTEGSLRK RDSQRAPEAM TVPLDTLKGL DTCFPSGPEL SGAGIAAAME RASERRTASA 60
LFAGFRALGL FSNDIPHVVR FSALKRRFCV TTCVGKSFHT YDVQKLSLVA VSNSVPQDIC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAGCTCTG GAGGGAGAAC TTTATGTGTT GCACTGAGGG CAGTCTCCGG AAACGCGATT 60
CGCAGCGGGC GCCGGAAGCG GTCTTCTGTC TTCAGCTCTA GTAGATGACT GTTCCACTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR007319--SSU_processome_Utp21
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF04192--Utp21
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0003723--F:RNA binding
GO:0030516--P:regulation of axon extension
GO:0001895--P:retina homeostasis
GO:0006364--P:rRNA processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001096	Aegilops tauschii	35.38	1.00e-144	507.00
IUUC-Aml-002289	Ailuropoda melanoleuca	91.96	0.00e+00	1730.00
IUUC-Atr-002859	Amborella trichopoda	32.48	5.00e-122	432.00
IUUC-Apl-003505	Anas platyrhynchos	74.44	0.00e+00	1220.00
IUUC-Aca-004339	Anolis carolinensis	72.64	0.00e+00	1298.00
IUUC-Aly-005913	Arabidopsis lyrata	36.51	9.00e-156	544.00
IUUC-Ath-006767	Arabidopsis thaliana	36.55	1.00e-158	553.00
IUUC-Ago-007763	Ashbya gossypii	32.62	7.00e-120	425.00
IUUC-Acl-008275	Aspergillus clavatus	32.81	1.00e-90	327.00
IUUC-Afl-008457	Aspergillus flavus	32.54	7.00e-90	325.00
IUUC-Afu-008914	Aspergillus fumigatus	33.25	2.00e-104	374.00
IUUC-Ani-009225	Aspergillus nidulans	32.11	7.00e-103	368.00
IUUC-Aor-010046	Aspergillus oryzae	31.81	1.00e-114	407.00
IUUC-Ate-010337	Aspergillus terreus	32.67	2.00e-115	410.00
IUUC-Ame-010963	Astyanax mexicanus	67.60	0.00e+00	1215.00
IUUC-Bgr-011973	Blumeria graminis	29.88	9.00e-112	398.00
IUUC-Bta-012462	Bos taurus	89.43	0.00e+00	1658.00
IUUC-Bci-013940	Botrytis cinerea	31.03	4.00e-113	402.00
IUUC-Bdi-014725	Brachypodium distachyon	34.79	8.00e-147	514.00
IUUC-Bol-016534	Brassica oleracea	35.81	3.00e-151	529.00
IUUC-Bra-016781	Brassica rapa	35.42	2.00e-149	523.00
IUUC-Cel-018581	Caenorhabditis elegans	28.78	2.00e-96	347.00
IUUC-Cja-019675	Callithrix jacchus	97.43	0.00e+00	1759.00
IUUC-Cfa-020118	Canis familiaris	92.70	0.00e+00	1647.00
IUUC-Cpo-021798	Cavia porcellus	93.23	0.00e+00	1624.00
IUUC-Cre-022566	Chlamydomonas reinhardtii	30.51	9.00e-29	121.00
IUUC-Csa-023547	Chlorocebus sabaeus	99.57	0.00e+00	1810.00
IUUC-Cho-024518	Choloepus hoffmanni	78.09	0.00e+00	1326.00
IUUC-Cin-025339	Ciona intestinalis	46.13	0.00e+00	786.00
IUUC-Cgl-026476	Colletotrichum gloeosporioides	29.49	3.00e-112	400.00
IUUC-Cne-026859	Cryptococcus neoformans	35.08	7.00e-146	511.00
IUUC-Cme-027173	Cyanidioschyzon merolae	27.88	3.00e-86	313.00
IUUC-Dre-027733	Danio rerio	64.92	0.00e+00	1192.00
IUUC-Dno-029439	Dasypus novemcinctus	92.85	0.00e+00	1654.00
IUUC-Dor-030329	Dipodomys ordii	77.30	0.00e+00	1388.00
IUUC-Dse-031511	Dothistroma septosporum	28.94	1.00e-103	371.00
IUUC-Dme-031694	Drosophila melanogaster	39.75	0.00e+00	689.00
IUUC-Ete-032930	Echinops telfairi	81.64	0.00e+00	1373.00
IUUC-Eca-033302	Equus caballus	91.57	0.00e+00	1726.00
IUUC-Eeu-034516	Erinaceus europaeus	89.03	0.00e+00	1725.00
IUUC-Fca-036064	Felis catus	94.32	0.00e+00	1665.00
IUUC-Fal-037024	Ficedula albicollis	72.09	0.00e+00	1296.00
IUUC-Fox-037787	Fusarium oxysporum	29.11	4.00e-95	343.00
IUUC-Fso-038378	Fusarium solani	29.21	3.00e-97	350.00
IUUC-Gmo-039637	Gadus morhua	52.86	3.00e-155	541.00
IUUC-Ggr-040108	Gaeumannomyces graminis	29.33	4.00e-105	376.00
IUUC-Gga-040982	Gallus gallus	72.92	0.00e+00	1330.00
IUUC-Gac-041565	Gasterosteus aculeatus	56.48	0.00e+00	956.00
IUUC-Gma-043414	Glycine max	34.98	3.00e-152	532.00
IUUC-Ggo-045463	Gorilla gorilla	97.27	0.00e+00	1853.00
IUUC-Hsa-045675	Homo sapiens	97.69	0.00e+00	1859.00
IUUC-Hvu-047352	Hordeum vulgare	34.47	6.00e-132	464.00
IUUC-Itr-048088	Ictidomys tridecemlineatus	93.20	0.00e+00	1706.00
IUUC-Kpa-049164	Komagataella pastoris	33.08	6.00e-113	402.00
IUUC-Lch-050476	Latimeria chalumnae	69.02	0.00e+00	1275.00
IUUC-Lpe-051556	Leersia perrieri	29.14	4.00e-94	338.00
IUUC-Loc-052820	Lepisosteus oculatus	68.95	0.00e+00	1241.00
IUUC-Lma-052961	Leptosphaeria maculans	32.50	9.00e-107	381.00
IUUC-Laf-054006	Loxodonta africana	91.02	0.00e+00	1623.00
IUUC-Mor-057280	Magnaporthe oryzae	29.71	1.00e-107	384.00
IUUC-Mpo-057408	Magnaporthe poae	29.27	2.00e-101	363.00
IUUC-Mtr-058473	Medicago truncatula	33.81	1.00e-149	523.00
IUUC-Mla-058892	Melampsora laricipopulina	33.51	1.00e-118	420.00
IUUC-Mga-059598	Meleagris gallopavo	61.77	0.00e+00	1028.00
IUUC-Mvi-060334	Microbotryum violaceum	34.79	1.00e-119	424.00
IUUC-Mmr-061239	Microcebus murinus	91.75	0.00e+00	1714.00
IUUC-Mdo-062471	Monodelphis domestica	80.96	0.00e+00	1429.00
IUUC-Mmu-063872	Mus musculus	88.75	0.00e+00	1649.00
IUUC-Mac-064631	Musa acuminata	34.62	6.00e-134	471.00
IUUC-Mpu-066039	Mustela putorius furo	94.64	0.00e+00	1716.00
IUUC-Mlu-067485	Myotis lucifugus	94.00	0.00e+00	1701.00
IUUC-Nfi-068319	Neosartorya fischeri	30.14	2.00e-102	367.00
IUUC-Ncr-068725	Neurospora crassa	29.29	2.00e-101	363.00
IUUC-Nle-069050	Nomascus leucogenys	97.16	0.00e+00	1855.00
IUUC-Opr-070437	Ochotona princeps	80.74	9.00e-141	494.00
IUUC-Ont-071574	Oreochromis niloticus	58.56	0.00e+00	1035.00
IUUC-Oan-072826	Ornithorhynchus anatinus	75.59	0.00e+00	1350.00
IUUC-Ocu-073995	Oryctolagus cuniculus	94.19	0.00e+00	1633.00
IUUC-Oba-075407	Oryza barthii	32.16	3.00e-120	426.00
IUUC-Obr-076451	Oryza brachyantha	35.38	1.00e-154	540.00
IUUC-Ogl-077535	Oryza glaberrima	34.93	2.00e-147	516.00
IUUC-Ogu-077995	Oryza glumaepatula	31.74	5.00e-119	422.00
IUUC-Oin-079431	Oryza indica	35.24	8.00e-150	524.00
IUUC-Olo-080495	Oryza longistaminata	31.74	1.00e-116	414.00
IUUC-Oni-082336	Oryza nivara	33.88	1.00e-137	484.00
IUUC-Opu-084028	Oryza punctata	33.11	2.00e-124	440.00
IUUC-Oru-084500	Oryza rufipogon	31.78	4.00e-118	419.00
IUUC-Osa-086242	Oryza sativa	35.13	1.00e-149	523.00
IUUC-Ola-086612	Oryzias latipes	55.89	0.00e+00	813.00
IUUC-Olu-087703	Ostreococcus lucimarinus	30.47	2.00e-108	387.00
IUUC-Oga-088572	Otolemur garnettii	92.33	0.00e+00	1661.00
IUUC-Oar-090363	Ovis aries	91.96	0.00e+00	1681.00
IUUC-Ptr-090477	Pan troglodytes	97.58	0.00e+00	1832.00
IUUC-Pan-092914	Papio anubis	99.66	0.00e+00	1783.00
IUUC-Psi-093019	Pelodiscus sinensis	73.60	0.00e+00	1322.00
IUUC-Pma-094303	Petromyzon marinus	50.88	0.00e+00	799.00
IUUC-Pno-094938	Phaeosphaeria nodorum	32.39	9.00e-100	358.00
IUUC-Ppa-095720	Physcomitrella patens	35.06	2.00e-149	523.00
IUUC-Pfo-097034	Poecilia formosa	56.73	0.00e+00	979.00
IUUC-Pab-097669	Pongo abelii	98.55	0.00e+00	1769.00
IUUC-Pop-098835	Populus trichocarpa	34.46	1.00e-147	517.00
IUUC-Pca-101097	Procavia capensis	79.90	0.00e+00	629.00
IUUC-Ppe-101430	Prunus persica	34.61	5.00e-152	531.00
IUUC-Pva-103152	Pteropus vampyrus	90.76	0.00e+00	1732.00
IUUC-Pgr-103517	Puccinia graminis	31.26	2.00e-124	440.00
IUUC-Ptt-103697	Puccinia triticina	32.33	3.00e-99	356.00
IUUC-Pte-104121	Pyrenophora teres	30.45	1.00e-106	380.00
IUUC-Pyt-104672	Pyrenophora triticirepentis	30.85	9.00e-109	388.00
IUUC-Rno-105435	Rattus norvegicus	89.19	0.00e+00	1618.00
IUUC-Sce-106202	Saccharomyces cerevisiae	31.77	2.00e-110	394.00
IUUC-Sha-107272	Sarcophilus harrisii	81.43	0.00e+00	1381.00
IUUC-Sja-107744	Schizosaccharomyces japonicus	35.19	2.00e-152	533.00
IUUC-Spo-108256	Schizosaccharomyces pombe	35.90	5.00e-152	531.00
IUUC-Ssl-108618	Sclerotinia sclerotiorum	30.97	6.00e-112	399.00
IUUC-Smo-108762	Selaginella moellendorffii	36.06	2.00e-155	543.00
IUUC-Sit-110051	Setaria italica	34.98	4.00e-148	518.00
IUUC-Sly-111181	Solanum lycopersicum	34.57	6.00e-152	531.00
IUUC-Stu-112018	Solanum tuberosum	34.16	2.00e-151	530.00
IUUC-Sar-113348	Sorex araneus	89.09	0.00e+00	1162.00
IUUC-Sbi-114282	Sorghum bicolor	35.16	2.00e-148	520.00
IUUC-Sre-114946	Sporisorium reilianum	32.27	1.00e-93	338.00
IUUC-Ssc-115287	Sus scrofa	89.83	0.00e+00	1712.00
IUUC-Tgu-117138	Taeniopygia guttata	68.86	0.00e+00	1093.00
IUUC-Tru-118232	Takifugu rubripes	58.25	0.00e+00	1009.00
IUUC-Tsy-119502	Tarsius syrichta	77.77	0.00e+00	1404.00
IUUC-Tni-120378	Tetraodon nigroviridis	57.06	0.00e+00	981.00
IUUC-Tca-121506	Theobroma cacao	34.83	8.00e-144	504.00
IUUC-Tre-122166	Trichoderma reesei	29.24	1.00e-105	377.00
IUUC-Tvi-122385	Trichoderma virens	29.17	8.00e-106	378.00
IUUC-Tae-122836	Triticum aestivum	34.75	4.00e-150	525.00
IUUC-Tur-126490	Triticum urartu	32.01	3.00e-112	399.00
IUUC-Tme-127157	Tuber melanosporum	33.63	3.00e-113	402.00
IUUC-Tbe-127981	Tupaia belangeri	85.56	0.00e+00	1441.00
IUUC-Ttr-128886	Tursiops truncatus	90.16	0.00e+00	1700.00
IUUC-Uma-129439	Ustilago maydis	32.01	9.00e-101	362.00
IUUC-Vda-129760	Verticillium dahliae	29.01	5.00e-103	369.00
IUUC-Vpa-130456	Vicugna pacos	90.83	0.00e+00	1727.00
IUUC-Vvi-131086	Vitis vinifera	33.99	3.00e-146	512.00
IUUC-Xtr-131829	Xenopus tropicalis	68.35	0.00e+00	1239.00
IUUC-Xma-133588	Xiphophorus maculatus	56.84	0.00e+00	964.00
IUUC-Yli-134328	Yarrowia lipolytica	31.24	4.00e-112	399.00
IUUC-Zma-135808	Zea mays	34.53	4.00e-147	515.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence