iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bol-015161

Ensembl Protein ID

Bo4g170760.1

UniProt Accession

A0A0D3C300; A0A0D3C300_BRAOL

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bo4g170760	Bo4g170760.1	Bo4g170760.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	7.80e-167	557.2	448	935

Active Site

Position(s)	Description	Evidence
629	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnvea 92
           YD Qi ++G++ q+kl+ a+v+ vG g+lGcE+lKn++l+Gv     g++tv+D+d +e+snl+rqFLfr++++g+ K+ vaa a++ +np+ n+ea
   Q: 448  YDAQISVFGAKLQKKLEDARVFTVGSGALGCEFLKNMALMGVscgnkGKLTVTDDDIIEKSNLSRQFLFRDWNIGQAKSTVAASAAAAINPKFNIEA 544
           ************************************************************************************************* PP
   S: 93   heesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaeht 186
            ++++ +++e+++   F ++++vVv+aldn+ ar++v+++cl+ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P+ct+ ++p +++h+
   Q: 545  LQNRVGAETENVFddaFWENLTVVVNALDNVNARLYVDSRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHC 641
           ***********99************************************************************************************ PP
   S: 187  iewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtksksp 271
           ++wa            + +n +l+   + ++       ++ +e+++++ + l++e+ enf+++ ++a+  f+ ++ n +kql+  f+ d  t+ ++p
   Q: 642  LTWArsefegllektpAEVNAYLSSPVEYTNSMMSAGDAQARETLERIVECLEKEKCENFQDCLNWARLRFEDYFVNRVKQLIYTFPEDAATSTGAP 738
           *********999999977777777777777777777788888899999999999******************************************* PP
   S: 272  fwv.........................................................sfcsnaealqvpekvekdeevvkasap..lylllral 309
           fw+                                                          f++ ++a+ v +  + + ++ +++++  +  l+++l
   Q: 739  FWSapkrfprplqysssdpsllnfitatailraetfgipvpewtknpkeaaeavdsvivpDFEPRKDAKIVTDEKATSLTTASVDDAtvINDLIAKL 835
           *********************************************9999999999999998888888777776666666666666667977788888 PP
   S: 310  erfekk..kgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknffl 400
           er +++  ++  ++ ++fekddd   ++d++  +an+ra +++i++ +d+ + k iag+iipaiat +a+  Gl+++E++Kv++g  k e+++n+f 
   Q: 836  ERCRHNlsPDFRMKPVQFEKDDDTnyHMDVISGLANMRARNYSIPE-VDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGghKVEAYRNTFA 931
           87766433889999********************************.***************************************9*********9 PP
   S: 401  fdae 404
           ++a+
   Q: 932  NLAL 935
           9875 PP

Organism

Brassica oleracea

Protein Sequence
(Fasta)

MLESVAASSP IKKRRIDTTG DNSTISASGS VVQHMAFGNN SNRPEIDEDL HSRQLAVYGR 60
ETMRRLFASN VLVSGMHGLG AEIAKNLILA GVKSVTLHDE RVVELWDLSS NFVFSEDDVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTTGAAT CAGTTGCTGC ATCGTCGCCG ATCAAGAAAC GCCGTATCGA TACCACTGGT 60
GATAACTCTA CGATCTCAGC TTCCGGCAGC GTCGTCCAGC ACATGGCTTT CGGTAATAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008181	Aspergillus clavatus	46.00	0.00e+00	822.00
IUUC-Bra-017707	Brassica rapa	97.82	0.00e+00	2111.00
IUUC-Cel-018260	Caenorhabditis elegans	37.80	0.00e+00	652.00
IUUC-Cme-027290	Cyanidioschyzon merolae	38.53	0.00e+00	682.00
IUUC-Dme-032045	Drosophila melanogaster	44.10	0.00e+00	844.00
IUUC-Loc-052936	Lepisosteus oculatus	44.62	0.00e+00	880.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence