iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-097862

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01058035

Gene Name

SCAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000013918.2	ENSPPYT00000016190.2	ENSPPYP00000015570.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.70e-15	54.9	1116	1149

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tl.lvsGsdDgtikvWDlrtg 33
           gH++ +t +   d t+ l+sG+ Dg i +WD+ tg
   Q: 1116 GHSGAITTVYI-DqTMvLASGGQDGAICLWDVLTG 1149
           8********88.446648*************9887 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MTLTERLREK ISRAFYNHGL LCASYPIPII LFTGFCILAC CYPLLKLPLP GTGPVEFTTP 60
VKDYSPPPVD SDRKQGEPTE QPEWYVGAPV AYVQQIFVKS SVFPWHKNLL AVDVFRSPLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTAGTGTGC AGAGCCAAGT ACTCTTTGTT AACTGGCTTT TCTCCTTTCT TACCAGGTAC 60
CTGCACATGT TGTTCTTTGT CAGTGCTGTC AAGTGTGTGC CAGGGTGATC CATGGTCACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0045540--P:regulation of cholesterol biosynthetic process
GO:0042304--P:regulation of fatty acid biosynthetic process
GO:0001666--P:response to hypoxia
GO:0032868--P:response to insulin
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	94.74	0.00e+00	1096.00
IUUC-Apl-003294	Anas platyrhynchos	76.55	0.00e+00	1728.00
IUUC-Aca-004424	Anolis carolinensis	70.00	0.00e+00	1524.00
IUUC-Bta-013478	Bos taurus	92.96	0.00e+00	2110.00
IUUC-Bol-016061	Brassica oleracea	26.29	3.00e-13	69.30
IUUC-Cel-018160	Caenorhabditis elegans	29.78	2.00e-64	241.00
IUUC-Cja-019123	Callithrix jacchus	95.78	0.00e+00	2176.00
IUUC-Cfa-021082	Canis familiaris	91.71	0.00e+00	2050.00
IUUC-Cpo-022477	Cavia porcellus	85.17	0.00e+00	1915.00
IUUC-Csa-023176	Chlorocebus sabaeus	95.46	0.00e+00	2175.00
IUUC-Cin-025490	Ciona intestinalis	38.26	7.00e-92	332.00
IUUC-Csv-026115	Ciona savignyi	37.12	2.00e-134	473.00
IUUC-Dre-028008	Danio rerio	67.98	0.00e+00	1528.00
IUUC-Dno-028887	Dasypus novemcinctus	91.73	0.00e+00	1221.00
IUUC-Dor-030467	Dipodomys ordii	93.09	0.00e+00	881.00
IUUC-Dme-032087	Drosophila melanogaster	32.99	3.00e-110	393.00
IUUC-Ete-032372	Echinops telfairi	77.55	0.00e+00	1726.00
IUUC-Eca-033896	Equus caballus	93.90	0.00e+00	2190.00
IUUC-Eeu-035099	Erinaceus europaeus	85.43	0.00e+00	1221.00
IUUC-Fca-035616	Felis catus	87.64	0.00e+00	1954.00
IUUC-Fal-037231	Ficedula albicollis	74.03	0.00e+00	1647.00
IUUC-Gmo-039439	Gadus morhua	65.65	0.00e+00	870.00
IUUC-Gac-041516	Gasterosteus aculeatus	67.51	0.00e+00	1519.00
IUUC-Hsa-046674	Homo sapiens	99.06	0.00e+00	2345.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	93.59	0.00e+00	2167.00
IUUC-Lch-049689	Latimeria chalumnae	70.68	0.00e+00	1654.00
IUUC-Loc-052417	Lepisosteus oculatus	53.87	1.00e-136	480.00
IUUC-Laf-053795	Loxodonta africana	91.14	0.00e+00	2111.00
IUUC-Mcc-055502	Macaca mulatta	98.59	0.00e+00	2299.00
IUUC-Mga-059805	Meleagris gallopavo	77.53	0.00e+00	1738.00
IUUC-Mmr-060997	Microcebus murinus	94.61	0.00e+00	2213.00
IUUC-Mdo-062940	Monodelphis domestica	81.38	0.00e+00	1835.00
IUUC-Mmu-063255	Mus musculus	92.25	0.00e+00	2130.00
IUUC-Mpu-066158	Mustela putorius furo	92.72	0.00e+00	2113.00
IUUC-Mlu-067201	Myotis lucifugus	88.79	0.00e+00	2059.00
IUUC-Nle-069145	Nomascus leucogenys	99.38	0.00e+00	1443.00
IUUC-Opr-070797	Ochotona princeps	88.35	0.00e+00	1968.00
IUUC-Ont-071553	Oreochromis niloticus	67.05	0.00e+00	1521.00
IUUC-Ocu-074598	Oryctolagus cuniculus	93.97	0.00e+00	2110.00
IUUC-Ola-086650	Oryzias latipes	84.23	9.00e-113	399.00
IUUC-Oar-089287	Ovis aries	86.13	0.00e+00	1117.00
IUUC-Pan-092004	Papio anubis	98.58	0.00e+00	2274.00
IUUC-Psi-093028	Pelodiscus sinensis	72.11	0.00e+00	1523.00
IUUC-Pma-094145	Petromyzon marinus	52.56	0.00e+00	1137.00
IUUC-Pfo-096320	Poecilia formosa	67.41	0.00e+00	1521.00
IUUC-Pca-100862	Procavia capensis	79.40	0.00e+00	1667.00
IUUC-Pva-103050	Pteropus vampyrus	92.71	0.00e+00	1341.00
IUUC-Rno-105852	Rattus norvegicus	92.80	0.00e+00	2157.00
IUUC-Sha-107312	Sarcophilus harrisii	81.87	0.00e+00	1850.00
IUUC-Sar-113311	Sorex araneus	89.86	0.00e+00	854.00
IUUC-Ssc-116356	Sus scrofa	92.73	0.00e+00	2150.00
IUUC-Tgu-116896	Taeniopygia guttata	60.70	3.00e-152	532.00
IUUC-Tru-118197	Takifugu rubripes	67.99	0.00e+00	1519.00
IUUC-Tni-119823	Tetraodon nigroviridis	65.72	0.00e+00	1494.00
IUUC-Ttr-129164	Tursiops truncatus	93.20	0.00e+00	2115.00
IUUC-Xtr-132819	Xenopus tropicalis	68.76	0.00e+00	1623.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence