iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndex	HINT	Mentha
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	23831064

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	1.80e-08	35.6	131	173

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf...kdgplvlp.CgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCl++f   ++ +++lp C H fh  C+ kw       s + +CP+Cr
   Q: 131  CAICLSEFvaeER-VKLLPtCHHGFHVRCIDKW------LSSHSSCPTCR 173
           ********99555.*******************......**********8 PP

Organism

Arabidopsis thaliana

Protein Sequence
(Fasta)

MCTTISISIS TIKPTEIFQE ILGSSYSRKL LFHTHDQSPT PAPSPYVGDN NFDANVVMVL 60
SVLLCALVCS LGLNSIIRCA LRCSNLVPSE AGGDNYPVRL TNTGVKRKAL KSFQTVSYST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTGAAAAAA AATTGAAACT TTACCTTTCC TCTATATAAA CAATTAGCCT CCAAACCTTT 60
ACTCTATATA AACAACCTCC AACGGAAACA CAGAAAGCCA CCAATCTATC TTAAAACTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

KEGG

ath:AT1G49230

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002440	Amborella trichopoda	53.85	3.00e-32	130.00
IUUC-Aly-006297	Arabidopsis lyrata	70.37	2.00e-69	254.00
IUUC-Bdi-014146	Brachypodium distachyon	44.55	6.00e-36	142.00
IUUC-Bol-016181	Brassica oleracea	83.57	3.00e-84	303.00
IUUC-Bra-017634	Brassica rapa	83.09	6.00e-84	302.00
IUUC-Gma-043621	Glycine max	58.49	4.00e-63	233.00
IUUC-Hvu-047571	Hordeum vulgare	45.27	9.00e-33	132.00
IUUC-Lpe-051348	Leersia perrieri	44.67	6.00e-33	132.00
IUUC-Mtr-058186	Medicago truncatula	64.80	2.00e-61	227.00
IUUC-Mac-065335	Musa acuminata	47.57	3.00e-39	154.00
IUUC-Obr-076307	Oryza brachyantha	47.49	7.00e-30	122.00
IUUC-Pno-095037	Phaeosphaeria nodorum	43.33	6.00e-09	54.30
IUUC-Pop-099910	Populus trichocarpa	62.50	1.00e-71	261.00
IUUC-Ppe-101930	Prunus persica	61.84	2.00e-62	231.00
IUUC-Sit-110398	Setaria italica	45.32	7.00e-30	122.00
IUUC-Sly-111559	Solanum lycopersicum	52.49	7.00e-51	192.00
IUUC-Stu-112198	Solanum tuberosum	54.46	1.00e-55	208.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence