iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ppe-101176

Ensembl Protein ID

EMJ23760

UniProt Accession

M5XX13; M5XX13_PRUPE

Genbank Protein ID

EMJ23760.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

KB638913

Gene Name

PRUPE_ppa008376mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PRUPE_ppa008376mg	EMJ23760	EMJ23760

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.40e-78	265.2	2	325

Active Site

Position(s)	Description	Evidence
82	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
157	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAllsv 107
           +w+++esdPg+ft+l+++  vk++ qveelysLd ++l+ + +pv+gl++lFk+ + ++  r           v +d   ++ffa qvi+N+Cat+A+ls 
   Q: 2    SWCTIESDPGVFTELIQQMQVKGV-QVEELYSLDLDSLNNL-RPVYGLIFLFKWRPGERDDR----------LVIKDPNPNLFFASQVINNACATQAILSI 90
           7***********************.****************.***************99999..........44467789********************* PP
   S: 108  llncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglkpfPldlgkk.. 206
           l nc d+  d+G++ls+lke+tk + pe k+la++n+++++++hns+ar+e++  +e++    + ++++++hf+sy +++g lyeldglk+ P+ lg++  
   Q: 91   LMNCPDV--DIGPELSKLKEFTKNFPPELKGLAINNSDAIRAAHNSFARPEPFIPEEQK---VAEKDDDVYHFISYLPVDGVLYELDGLKEGPISLGQCpg 186
           *******..********************************************988777...55569*******************************988 PP
   S: 207  .keteelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkid......................keLlkLlkdieseeekieaqlddek 284
            + + e+ + ++ v+   eri+ +++ eirfnllai ++r+ ++t+ l+ l+                        + L k l++i++ +e   +++  e+
   Q: 187  gQGDMEWLQMVQPVI--QERIERYSKSEIRFNLLAIIKNRKEMYTAELKELQKKrerilqqlsalqserpadsskfEALNKGLSEINAGIEGATEKILMEE 285
           78899**********..******************************987777789*******************99999********************* PP
   S: 285  ekrkkfkiddirRtenydeficifikdlaregilrklvee 324
           ek kk+  ++irR++ny  f++ f+k la++++l+ l e+
   Q: 286  EKFKKWRTENIRRKHNYIPFLFNFLKILAEKKQLKPLIEK 325
           ***********************************99987 PP

Organism

Prunus persica

Protein Sequence
(Fasta)

MSWCTIESDP GVFTELIQQM QVKGVQVEEL YSLDLDSLNN LRPVYGLIFL FKWRPGERDD 60
RLVIKDPNPN LFFASQVINN ACATQAILSI LMNCPDVDIG PELSKLKEFT KNFPPELKGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACAGACTAC GGGTTCAAAA TCTCACAAGG AAGACTGAAA GAGAGAGAGA AGGAGCGGTG 60
GAGGAGGCTG ACGACGTCGT TCGTCTTGAT TTCTGGTGAG CTTATCTTCT TCCTCGTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

pper:PRUPE_ppa008376mg

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	76.90	5.00e-147	512.00
IUUC-Aml-001866	Ailuropoda melanoleuca	50.61	2.00e-88	317.00
IUUC-Atr-002966	Amborella trichopoda	79.64	3.00e-151	526.00
IUUC-Apl-003306	Anas platyrhynchos	46.20	2.00e-80	291.00
IUUC-Aca-004763	Anolis carolinensis	49.69	2.00e-86	311.00
IUUC-Aly-005581	Arabidopsis lyrata	80.24	4.00e-140	489.00
IUUC-Ath-007283	Arabidopsis thaliana	79.94	1.00e-143	501.00
IUUC-Ago-007999	Ashbya gossypii	36.26	8.00e-33	133.00
IUUC-Acl-008231	Aspergillus clavatus	49.79	2.00e-61	228.00
IUUC-Afl-008557	Aspergillus flavus	46.54	2.00e-59	221.00
IUUC-Afu-008988	Aspergillus fumigatus	49.79	4.00e-61	227.00
IUUC-Ani-009420	Aspergillus nidulans	40.23	7.00e-60	223.00
IUUC-Ang-009859	Aspergillus niger	48.15	5.00e-58	216.00
IUUC-Aor-010145	Aspergillus oryzae	46.54	2.00e-59	221.00
IUUC-Ate-010347	Aspergillus terreus	44.53	8.00e-59	219.00
IUUC-Ame-010791	Astyanax mexicanus	50.60	8.00e-90	322.00
IUUC-Bgr-012298	Blumeria graminis	38.51	4.00e-58	217.00
IUUC-Bta-013251	Bos taurus	50.31	5.00e-88	316.00
IUUC-Bci-013786	Botrytis cinerea	39.94	2.00e-62	231.00
IUUC-Bdi-014132	Brachypodium distachyon	76.60	2.00e-140	490.00
IUUC-Bol-015611	Brassica oleracea	77.81	9.00e-145	504.00
IUUC-Bra-017769	Brassica rapa	77.81	3.00e-144	503.00
IUUC-Cel-018604	Caenorhabditis elegans	41.39	8.00e-68	249.00
IUUC-Cja-019768	Callithrix jacchus	46.33	1.00e-82	299.00
IUUC-Cfa-020207	Canis familiaris	50.61	2.00e-88	317.00
IUUC-Cpo-021925	Cavia porcellus	47.85	4.00e-82	297.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	49.55	1.00e-83	301.00
IUUC-Csa-023958	Chlorocebus sabaeus	50.31	8.00e-88	316.00
IUUC-Cho-024928	Choloepus hoffmanni	58.11	4.00e-20	90.90
IUUC-Cin-025771	Ciona intestinalis	41.27	2.00e-66	245.00
IUUC-Csv-026149	Ciona savignyi	43.24	2.00e-71	261.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	36.76	6.00e-50	190.00
IUUC-Cne-026955	Cryptococcus neoformans	32.85	4.00e-45	174.00
IUUC-Cme-027104	Cyanidioschyzon merolae	30.73	1.00e-44	172.00
IUUC-Dre-027409	Danio rerio	50.00	5.00e-89	320.00
IUUC-Dno-028921	Dasypus novemcinctus	50.61	4.00e-88	317.00
IUUC-Dor-030891	Dipodomys ordii	46.67	3.00e-39	155.00
IUUC-Dse-031170	Dothistroma septosporum	39.58	5.00e-60	223.00
IUUC-Dme-031677	Drosophila melanogaster	47.13	1.00e-80	292.00
IUUC-Ete-032646	Echinops telfairi	45.98	8.00e-47	181.00
IUUC-Eca-033776	Equus caballus	49.67	7.00e-80	289.00
IUUC-Eeu-035305	Erinaceus europaeus	45.60	4.00e-40	157.00
IUUC-Fca-035846	Felis catus	46.74	1.00e-83	302.00
IUUC-Fal-037597	Ficedula albicollis	48.37	8.00e-76	276.00
IUUC-Fox-037670	Fusarium oxysporum	49.15	4.00e-54	204.00
IUUC-Fso-038243	Fusarium solani	50.00	3.00e-54	204.00
IUUC-Gmo-038499	Gadus morhua	46.32	2.00e-79	288.00
IUUC-Ggr-039975	Gaeumannomyces graminis	45.68	3.00e-53	201.00
IUUC-Gga-040904	Gallus gallus	50.00	3.00e-89	320.00
IUUC-Gac-042058	Gasterosteus aculeatus	49.39	5.00e-87	313.00
IUUC-Gma-043030	Glycine max	91.02	2.00e-176	610.00
IUUC-Ggo-044699	Gorilla gorilla	47.17	1.00e-76	278.00
IUUC-Hsa-046227	Homo sapiens	50.61	2.00e-88	318.00
IUUC-Hvu-047359	Hordeum vulgare	75.99	1.00e-144	504.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	46.22	5.00e-83	300.00
IUUC-Lch-049829	Latimeria chalumnae	49.69	3.00e-87	314.00
IUUC-Lpe-050899	Leersia perrieri	76.85	2.00e-134	470.00
IUUC-Loc-052264	Lepisosteus oculatus	49.24	6.00e-85	306.00
IUUC-Lma-053110	Leptosphaeria maculans	51.32	4.00e-55	207.00
IUUC-Laf-053639	Loxodonta africana	50.61	2.00e-88	317.00
IUUC-Mcc-055506	Macaca mulatta	50.31	8.00e-88	316.00
IUUC-Meu-056267	Macropus eugenii	43.30	6.00e-52	198.00
IUUC-Mor-057001	Magnaporthe oryzae	47.35	6.00e-58	216.00
IUUC-Mpo-057608	Magnaporthe poae	45.45	9.00e-37	145.00
IUUC-Mtr-057731	Medicago truncatula	87.72	1.00e-164	571.00
IUUC-Mla-059016	Melampsora laricipopulina	46.23	7.00e-45	172.00
IUUC-Mga-060178	Meleagris gallopavo	49.20	4.00e-81	293.00
IUUC-Mvi-060353	Microbotryum violaceum	38.86	1.00e-55	209.00
IUUC-Mmr-060738	Microcebus murinus	50.92	1.00e-88	318.00
IUUC-Mdo-062266	Monodelphis domestica	52.88	3.00e-62	230.00
IUUC-Mmu-063619	Mus musculus	50.61	3.00e-88	317.00
IUUC-Mac-065301	Musa acuminata	83.48	6.00e-164	568.00
IUUC-Mpu-066058	Mustela putorius furo	50.31	4.00e-88	317.00
IUUC-Mlu-067292	Myotis lucifugus	50.00	5.00e-88	316.00
IUUC-Nfi-068275	Neosartorya fischeri	39.32	4.00e-62	230.00
IUUC-Ncr-068713	Neurospora crassa	40.00	3.00e-59	221.00
IUUC-Nle-069013	Nomascus leucogenys	50.31	4.00e-88	317.00
IUUC-Opr-070628	Ochotona princeps	44.60	2.00e-77	281.00
IUUC-Ont-072688	Oreochromis niloticus	48.62	1.00e-85	309.00
IUUC-Oan-073004	Ornithorhynchus anatinus	49.59	8.00e-65	239.00
IUUC-Ocu-074303	Oryctolagus cuniculus	50.31	8.00e-88	317.00
IUUC-Oba-075002	Oryza barthii	74.10	2.00e-139	487.00
IUUC-Obr-076392	Oryza brachyantha	74.38	6.00e-136	475.00
IUUC-Ogl-077271	Oryza glaberrima	74.10	2.00e-139	487.00
IUUC-Ogu-078493	Oryza glumaepatula	74.40	2.00e-140	491.00
IUUC-Oin-080084	Oryza indica	74.40	2.00e-140	491.00
IUUC-Olo-080803	Oryza longistaminata	74.10	4.00e-140	489.00
IUUC-Ome-081146	Oryza meridionalis	73.80	6.00e-139	486.00
IUUC-Oni-082146	Oryza nivara	74.40	2.00e-140	491.00
IUUC-Opu-083633	Oryza punctata	74.69	1.00e-135	474.00
IUUC-Oru-084789	Oryza rufipogon	74.40	2.00e-140	491.00
IUUC-Osa-086196	Oryza sativa	74.40	2.00e-140	491.00
IUUC-Ola-087126	Oryzias latipes	48.47	2.00e-85	308.00
IUUC-Olu-087665	Ostreococcus lucimarinus	44.77	2.00e-74	271.00
IUUC-Oga-089140	Otolemur garnettii	47.03	6.00e-84	303.00
IUUC-Oar-090296	Ovis aries	50.46	3.00e-87	313.00
IUUC-Ptr-090566	Pan troglodytes	50.61	2.00e-88	318.00
IUUC-Pan-092052	Papio anubis	50.31	9.00e-88	316.00
IUUC-Psi-093723	Pelodiscus sinensis	49.67	2.00e-78	285.00
IUUC-Pma-094568	Petromyzon marinus	48.17	1.00e-60	225.00
IUUC-Pno-095120	Phaeosphaeria nodorum	50.88	2.00e-56	211.00
IUUC-Ppa-095761	Physcomitrella patens	72.22	8.00e-139	485.00
IUUC-Pfo-096210	Poecilia formosa	50.00	1.00e-87	315.00
IUUC-Pab-098463	Pongo abelii	50.61	1.00e-88	318.00
IUUC-Pop-099109	Populus trichocarpa	88.22	2.00e-170	590.00
IUUC-Pca-100108	Procavia capensis	53.11	4.00e-71	260.00
IUUC-Pva-102629	Pteropus vampyrus	50.76	3.00e-73	267.00
IUUC-Pgr-103419	Puccinia graminis	46.19	5.00e-56	210.00
IUUC-Pte-104207	Pyrenophora teres	52.12	5.00e-40	155.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	50.00	2.00e-58	218.00
IUUC-Rno-105579	Rattus norvegicus	43.99	2.00e-75	274.00
IUUC-Sha-106894	Sarcophilus harrisii	49.31	3.00e-75	274.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	41.72	3.00e-63	234.00
IUUC-Spo-108371	Schizosaccharomyces pombe	42.06	3.00e-70	257.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	37.38	2.00e-49	187.00
IUUC-Smo-109222	Selaginella moellendorffii	75.00	3.00e-136	476.00
IUUC-Sit-110630	Setaria italica	75.45	3.00e-142	496.00
IUUC-Sly-110972	Solanum lycopersicum	86.67	1.00e-165	574.00
IUUC-Stu-112185	Solanum tuberosum	87.43	7.00e-178	615.00
IUUC-Sar-113294	Sorex araneus	44.32	1.00e-76	278.00
IUUC-Sbi-113951	Sorghum bicolor	75.15	1.00e-141	494.00
IUUC-Ssc-115501	Sus scrofa	48.90	2.00e-81	294.00
IUUC-Tgu-117152	Taeniopygia guttata	48.37	8.00e-76	276.00
IUUC-Tru-118388	Takifugu rubripes	48.77	8.00e-87	312.00
IUUC-Tsy-119109	Tarsius syrichta	50.61	1.00e-88	318.00
IUUC-Tni-120048	Tetraodon nigroviridis	48.77	6.00e-87	313.00
IUUC-Tca-121750	Theobroma cacao	90.75	0.00e+00	635.00
IUUC-Tre-122130	Trichoderma reesei	48.28	1.00e-56	212.00
IUUC-Tvi-122284	Trichoderma virens	40.58	3.00e-55	207.00
IUUC-Tae-124082	Triticum aestivum	76.60	6.00e-146	509.00
IUUC-Tur-126366	Triticum urartu	64.72	2.00e-109	388.00
IUUC-Tme-127187	Tuber melanosporum	41.72	1.00e-68	252.00
IUUC-Tbe-127619	Tupaia belangeri	44.12	7.00e-61	226.00
IUUC-Ttr-128867	Tursiops truncatus	46.96	3.00e-60	224.00
IUUC-Vda-129912	Verticillium dahliae	38.78	2.00e-56	211.00
IUUC-Vpa-130552	Vicugna pacos	54.59	1.00e-62	232.00
IUUC-Vvi-130881	Vitis vinifera	90.42	3.00e-175	606.00
IUUC-Xtr-131934	Xenopus tropicalis	49.11	2.00e-89	321.00
IUUC-Xma-133312	Xiphophorus maculatus	50.00	2.00e-87	314.00
IUUC-Yli-134487	Yarrowia lipolytica	34.60	1.00e-54	205.00
IUUC-Zma-135639	Zea mays	65.50	2.00e-126	444.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence