iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059994

UUCD1 version

UUC-MeG-00369

Ensembl Protein ID

ENSMGAP00000008122.2

UniProt Accession

G1N7E2; G1N7E2_MELGA

Protein Name

Uncharacterized protein

Gene Name

KLHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000007917.2	ENSMGAT00000008911.2	ENSMGAP00000008122.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	9.60e-22	76.9	54	120
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.80e-11	41.1	153	184

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv++v + +e +ah++vLaa+S++F a+f+++++esk  +++eikdv+ + +r l++++Yt +++ +
   Q: 54   CDVVIVAETVEMEAHRVVLAACSPYFCAMFTGDMSESK-AKKIEIKDVDGQTLRKLIDYIYTAEIEVT 120
           8*************************************.************************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nclgi++fAd + c++L ++a+ ++++hF+
   Q: 153  PTNCLGIRAFADVHACTELLQQANAYAEQHFP 184
           78*****************************6 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

LFYLPLPAGS IKQSSRSSEA GEDEKDQRTV TVNPSHMRKA FKVMNELRSK RLLCDVVIVA 60
ETVEMEAHRV VLAACSPYFC AMFTGDMSES KAKKIEIKDV DGQTLRKLID YIYTAEIEVT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGTTTTATT TGCCTTTGCC GGCTGGAAGG TTCGAGGTAT GAGCTGTAGA TTTAAGTGGA 60
ACAGTTATCT CACTCTAAAA TGCTGCTTTG TTTTACAGGT GGGAACCTTT AGCTCAGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0072156--P:distal tubule morphogenesis
GO:0050801--P:ion homeostasis
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0070294--P:renal sodium ion absorption

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001632	Ailuropoda melanoleuca	94.56	0.00e+00	1022.00
IUUC-Apl-003965	Anas platyrhynchos	99.06	0.00e+00	1042.00
IUUC-Aca-004912	Anolis carolinensis	94.49	0.00e+00	984.00
IUUC-Ame-010670	Astyanax mexicanus	79.51	0.00e+00	843.00
IUUC-Bta-013354	Bos taurus	94.37	0.00e+00	1021.00
IUUC-Bol-016582	Brassica oleracea	30.28	2.00e-13	70.90
IUUC-Bra-017771	Brassica rapa	31.02	1.00e-13	72.00
IUUC-Cel-018136	Caenorhabditis elegans	41.57	2.00e-114	405.00
IUUC-Cja-019183	Callithrix jacchus	90.80	0.00e+00	889.00
IUUC-Cfa-020465	Canis familiaris	94.36	0.00e+00	1019.00
IUUC-Cpo-022115	Cavia porcellus	94.31	0.00e+00	1021.00
IUUC-Csa-024219	Chlorocebus sabaeus	95.07	0.00e+00	1025.00
IUUC-Csv-026032	Ciona savignyi	60.34	0.00e+00	628.00
IUUC-Cgl-026620	Colletotrichum gloeosporioides	30.29	4.00e-21	94.70
IUUC-Dre-028524	Danio rerio	73.88	0.00e+00	860.00
IUUC-Dno-029075	Dasypus novemcinctus	96.64	0.00e+00	1004.00
IUUC-Dor-030156	Dipodomys ordii	77.13	0.00e+00	803.00
IUUC-Dse-031229	Dothistroma septosporum	27.85	2.00e-05	42.40
IUUC-Dme-032172	Drosophila melanogaster	58.71	7.00e-178	617.00
IUUC-Ete-033064	Echinops telfairi	80.42	0.00e+00	826.00
IUUC-Eca-033887	Equus caballus	95.07	0.00e+00	1020.00
IUUC-Eeu-035244	Erinaceus europaeus	73.06	0.00e+00	768.00
IUUC-Fca-035375	Felis catus	94.00	0.00e+00	1016.00
IUUC-Fal-037119	Ficedula albicollis	99.40	0.00e+00	985.00
IUUC-Gmo-038811	Gadus morhua	72.89	0.00e+00	717.00
IUUC-Gga-041094	Gallus gallus	99.81	0.00e+00	1024.00
IUUC-Gac-042585	Gasterosteus aculeatus	77.54	0.00e+00	821.00
IUUC-Ggo-045485	Gorilla gorilla	94.34	0.00e+00	1014.00
IUUC-Hsa-046717	Homo sapiens	94.88	0.00e+00	1024.00
IUUC-Itr-048605	Ictidomys tridecemlineatus	94.56	0.00e+00	1028.00
IUUC-Lch-050246	Latimeria chalumnae	88.27	0.00e+00	906.00
IUUC-Loc-052780	Lepisosteus oculatus	79.96	0.00e+00	824.00
IUUC-Laf-053700	Loxodonta africana	95.57	0.00e+00	1014.00
IUUC-Mcc-054732	Macaca mulatta	97.55	0.00e+00	895.00
IUUC-Meu-056011	Macropus eugenii	80.25	0.00e+00	792.00
IUUC-Mmr-061067	Microcebus murinus	76.78	0.00e+00	827.00
IUUC-Mdo-062923	Monodelphis domestica	95.45	0.00e+00	1023.00
IUUC-Mmu-063842	Mus musculus	94.31	0.00e+00	1010.00
IUUC-Mpu-066380	Mustela putorius furo	93.48	0.00e+00	1016.00
IUUC-Mlu-067922	Myotis lucifugus	94.75	0.00e+00	1024.00
IUUC-Nle-069761	Nomascus leucogenys	94.69	0.00e+00	1022.00
IUUC-Opr-070287	Ochotona princeps	85.55	0.00e+00	895.00
IUUC-Ont-071654	Oreochromis niloticus	79.58	0.00e+00	859.00
IUUC-Oan-073699	Ornithorhynchus anatinus	79.42	0.00e+00	728.00
IUUC-Ocu-074957	Oryctolagus cuniculus	94.14	0.00e+00	1005.00
IUUC-Ola-086853	Oryzias latipes	77.55	0.00e+00	810.00
IUUC-Oga-088559	Otolemur garnettii	94.14	0.00e+00	1013.00
IUUC-Oar-089925	Ovis aries	94.90	0.00e+00	1018.00
IUUC-Ptr-091487	Pan troglodytes	94.88	0.00e+00	1024.00
IUUC-Pan-091705	Papio anubis	95.07	0.00e+00	1025.00
IUUC-Psi-093478	Pelodiscus sinensis	92.42	0.00e+00	956.00
IUUC-Pma-094177	Petromyzon marinus	73.57	0.00e+00	783.00
IUUC-Pfo-097450	Poecilia formosa	79.58	0.00e+00	796.00
IUUC-Pab-097618	Pongo abelii	94.69	0.00e+00	1021.00
IUUC-Pca-100607	Procavia capensis	63.91	0.00e+00	644.00
IUUC-Pva-102218	Pteropus vampyrus	72.80	0.00e+00	767.00
IUUC-Rno-105250	Rattus norvegicus	77.11	0.00e+00	828.00
IUUC-Sha-106935	Sarcophilus harrisii	98.12	0.00e+00	637.00
IUUC-Sar-113249	Sorex araneus	78.38	0.00e+00	821.00
IUUC-Ssc-115599	Sus scrofa	95.06	0.00e+00	1020.00
IUUC-Tgu-117001	Taeniopygia guttata	99.42	0.00e+00	1024.00
IUUC-Tru-118078	Takifugu rubripes	78.61	0.00e+00	849.00
IUUC-Tsy-119161	Tarsius syrichta	82.64	0.00e+00	869.00
IUUC-Tni-120888	Tetraodon nigroviridis	75.33	0.00e+00	794.00
IUUC-Tbe-127285	Tupaia belangeri	80.87	0.00e+00	646.00
IUUC-Ttr-128884	Tursiops truncatus	78.24	5.00e-145	507.00
IUUC-Vpa-130707	Vicugna pacos	77.07	0.00e+00	631.00
IUUC-Xtr-132035	Xenopus tropicalis	76.07	0.00e+00	843.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence