iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088114

Ensembl Protein ID

ENSOGAP00000016525.1

UniProt Accession

H0XK85; H0XK85_OTOGA

Genbank Protein ID

ENSOGAP00000016525

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

AAQR03136325

Gene Name

LOC100951173

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000026459.1	ENSOGAT00000030068.1	ENSOGAP00000016525.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	36.43	5.00e-41	164.00	IUUC-Ath-007192

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Otolemur garnettii

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MSRRPDRARP AGPSQGPPRQ GEPDLSAMTP SSSHLRSLFE CPVCFDYVLP PILQCQRGHL 60
VCISCRQKLT SCPTCRGPLG SIRNLAMEKV ADSLSFPCKY APSGCRITLP PAGKADHEEV 120

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Nucleotide Sequence
(Fasta)

ATGAGCCGTC GGCCTGACAG GGCACGGCCC GCTGGTCCCT CACAGGGTCC ACCACGCCAG 60
GGGGAGCCGG ACCTGTCTGC CATGACTCCA TCCAGCAGCC ACTTGAGGAG CCTTTTCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-003118	Amborella trichopoda	36.19	4.00e-42	164.00
IUUC-Aly-006522	Arabidopsis lyrata	36.82	2.00e-42	166.00
IUUC-Ath-007192	Arabidopsis thaliana	36.43	5.00e-42	164.00
IUUC-Bol-015983	Brassica oleracea	35.69	2.00e-42	165.00
IUUC-Bra-017336	Brassica rapa	36.82	2.00e-43	169.00
IUUC-Gma-042926	Glycine max	35.34	2.00e-41	162.00
IUUC-Hvu-047574	Hordeum vulgare	37.19	2.00e-44	172.00
IUUC-Lpe-050879	Leersia perrieri	39.68	6.00e-43	167.00
IUUC-Mtr-058422	Medicago truncatula	36.90	2.00e-42	166.00
IUUC-Mac-065014	Musa acuminata	37.13	3.00e-44	172.00
IUUC-Obr-076037	Oryza brachyantha	35.32	1.00e-41	163.00
IUUC-Olo-080244	Oryza longistaminata	35.85	1.00e-41	164.00
IUUC-Ppa-095212	Physcomitrella patens	36.82	1.00e-42	166.00
IUUC-Pop-099563	Populus trichocarpa	36.50	7.00e-44	170.00
IUUC-Ppe-101760	Prunus persica	35.42	6.00e-44	171.00
IUUC-Smo-109412	Selaginella moellendorffii	36.03	1.00e-39	157.00
IUUC-Sit-110595	Setaria italica	38.19	1.00e-41	163.00
IUUC-Sly-111259	Solanum lycopersicum	38.49	1.00e-43	169.00
IUUC-Stu-112571	Solanum tuberosum	38.49	1.00e-43	170.00
IUUC-Tca-121228	Theobroma cacao	36.09	9.00e-43	166.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence