iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Spo-108155

Ensembl Protein ID

SPAC25H1.07.1:pep

UniProt Accession

O13981; Q9USE4; EMC1_SCHPO

Genbank Protein ID

CAB11603.1; BAA87126.1

Protein Name

ER membrane protein complex subunit 1

Genbank Nucleotide ID

CU329670; AB027822

Gene Name

emc1; SPAC25H1.07

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPAC25H1.07	SPAC25H1.07.1	SPAC25H1.07.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	36.67	1.00e+00	27.30	IUUC-Ots-000053

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Schizosaccharomyces pombe

Functional Description
(View)

The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).

Protein Sequence
(Fasta)

MLRPLWPLFL TALFLNIYRA ASVLIDEAGK NDFEISLLGK VNDLVYDTKN EYLYAVSQKG 60
LLAKLNASNG DVIWRQSIAP ETSQLNYNPV TNFIITVDKD YLYIWNSKNG ILDRKIELAD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCAGTAAA CTGTGTTGTA GTTCGCTACT CCTCAGTATA TTTGATACCT TGCATTAACA 60
ATAGGAACTA TACAGGTACT GGACTACATA CCATCTTTTC ATATCAGTTA CGATGTTACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0325--Glycoprotein
KW-0472--Membrane
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR026895--EMC1
IPR011678--EMC1_C
IPR027295--Quinoprotein_ADH-like_fam
IPR011047--Quinoprotein_ADH-like_supfam

Pfam

PF07774--DUF1620

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0072546--C:ER membrane protein complex
GO:0034975--P:protein folding in endoplasmic reticulum

KEGG

spo:SPAC25H1.07

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001079	Aegilops tauschii	27.27	8.20e-02	29.30
IUUC-Aly-006185	Arabidopsis lyrata	26.32	7.70e-01	26.90
IUUC-Ath-006919	Arabidopsis thaliana	26.32	4.70e-01	27.70
IUUC-Bci-013735	Botrytis cinerea	26.80	5.30e-01	28.10
IUUC-Bol-016591	Brassica oleracea	26.32	4.90e-01	27.70
IUUC-Gmo-038899	Gadus morhua	31.58	2.10e-01	29.60

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence