iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059896

UUCD1 version

UUC-MeG-00858

Ensembl Protein ID

ENSMGAP00000007473.2

UniProt Accession

G1N623; G1N623_MELGA

Protein Name

Uncharacterized protein

Gene Name

USP48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000007331.2	ENSMGAT00000008248.2	ENSMGAP00000007473.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.90e-73	247.3	47	375
ULD/UDP/UBQ/UBQ_Other	1.00e-10	41.0	906	964

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaee 83
           +Gl+Nlg+tCY+N  LQ+ +   elr++l           e++++++ + + ++++++lq lf+ l++s++++++p+ ++kal+     
   Q: 47   VGLTNLGATCYVNTFLQMWFLNLELRQALYLcssnehTVGESIPKDKVDYEPQTICEHLQYLFALLQNSRRRYIDPSGFVKALG----- 130
           6***************************9998766555555666666688888******************************9..... PP
   S: 84   fsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           +++ +qqDaqEf + +++ le++l                        +k++   ++++++ F g++   ++c++c+++s+  ++f++l
   Q: 131  LDTGQQQDAQEFSKLFMSLLEDTL------------------------SKQNPDVRNIVQKQFCGEYAYVTVCNQCGRESKLVSKFYEL 195
           78899*******************........................5788999********************************** PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +l+++g++     +l+dc+ +f kee+leg+n+y+ce+c++kq+a++k++l +lP +L l+L+Rf f++++++++k+n+++ f + Ld+
   Q: 196  ELNIQGHK-----QLTDCITEFLKEEKLEGDNRYFCETCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSELLDM 279
           ********.....9**********************************************************************99*** PP
   S: 262  spfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetg..................... 327
           +pf+++++      + YeL+av++H G s+ sGHY+a+vk+ + + W++f+D+ +++++ ++ +   +                     
   Q: 280  EPFMEQKNG----VYVYELSAVLIHRGvSAYSGHYIAHVKDPQTGeWYKFNDEDIEKMEGKKLQLGIEedlaepsksqtrkpkcgkgth 364
           ******553....79**************************55555************9999998665999****************** PP
   S: 328  ..staYvlfYk 336
             ++aY+l+Y+
   Q: 365  csRNAYMLVYR 375
           **********8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 17   vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           v+   t +eLK +i +++++ p +q+L + GkiL +d  tL+++g+ ++s+i+l  +++
   Q: 906  VSANQTLKELKIQIMHAFSVAPFDQNLSINGKILsDDTATLGSLGVIPESVILLKADEP 964
           88899************************************************988775 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

SCRRNCRGNP NCLVGIGEHV WLGEIDENSF HNIDDPNCER RKKNAFVGLT NLGATCYVNT 60
FLQMWFLNLE LRQALYLCSS NEHTVGESIP KDKVDYEPQT ICEHLQYLFA LLQNSRRRYI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCTGGTCC TGCAGGAGGA ACTGCCGGGG AAACCCCAAC TGTCTGGTGG GCATCGGGGA 60
GCACGTCTGG CTGGGCGAGA TCGACGAGAA CAGCTTCCAC AACATCGATG ATCCCAACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	28.39	3.00e-79	289.00
IUUC-Aml-001357	Ailuropoda melanoleuca	86.20	0.00e+00	1718.00
IUUC-Atr-002976	Amborella trichopoda	28.04	7.00e-75	275.00
IUUC-Apl-003773	Anas platyrhynchos	95.62	0.00e+00	1815.00
IUUC-Aca-004466	Anolis carolinensis	83.96	0.00e+00	900.00
IUUC-Aly-006249	Arabidopsis lyrata	30.72	3.00e-71	263.00
IUUC-Ath-006700	Arabidopsis thaliana	31.91	4.00e-81	296.00
IUUC-Ame-011554	Astyanax mexicanus	68.16	0.00e+00	1352.00
IUUC-Bta-012573	Bos taurus	86.04	0.00e+00	1724.00
IUUC-Bdi-014149	Brachypodium distachyon	32.34	4.00e-79	289.00
IUUC-Bol-016289	Brassica oleracea	29.73	4.00e-80	292.00
IUUC-Bra-017494	Brassica rapa	33.06	3.00e-82	299.00
IUUC-Cel-018662	Caenorhabditis elegans	28.99	5.00e-32	133.00
IUUC-Cja-019991	Callithrix jacchus	85.22	0.00e+00	1717.00
IUUC-Cfa-020294	Canis familiaris	86.31	0.00e+00	1747.00
IUUC-Cpo-021706	Cavia porcellus	84.50	0.00e+00	1703.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	32.60	3.00e-40	161.00
IUUC-Csa-023931	Chlorocebus sabaeus	86.11	0.00e+00	1729.00
IUUC-Cho-024566	Choloepus hoffmanni	84.75	3.00e-135	475.00
IUUC-Cin-025307	Ciona intestinalis	51.15	6.00e-71	260.00
IUUC-Csv-026006	Ciona savignyi	36.59	4.00e-145	508.00
IUUC-Cne-027065	Cryptococcus neoformans	27.24	6.00e-65	242.00
IUUC-Dre-027624	Danio rerio	68.47	0.00e+00	1384.00
IUUC-Dno-029633	Dasypus novemcinctus	87.33	0.00e+00	1174.00
IUUC-Dor-030809	Dipodomys ordii	66.09	0.00e+00	977.00
IUUC-Ete-032818	Echinops telfairi	82.68	0.00e+00	848.00
IUUC-Eca-033692	Equus caballus	86.61	0.00e+00	1738.00
IUUC-Eeu-035185	Erinaceus europaeus	66.01	0.00e+00	677.00
IUUC-Fca-035676	Felis catus	86.11	0.00e+00	1746.00
IUUC-Fal-036913	Ficedula albicollis	94.49	0.00e+00	1877.00
IUUC-Gmo-038532	Gadus morhua	64.18	0.00e+00	1305.00
IUUC-Gga-041041	Gallus gallus	97.90	0.00e+00	1943.00
IUUC-Gac-042570	Gasterosteus aculeatus	65.61	0.00e+00	1342.00
IUUC-Gma-044136	Glycine max	30.25	3.00e-90	326.00
IUUC-Ggo-045367	Gorilla gorilla	81.87	0.00e+00	1608.00
IUUC-Hsa-046019	Homo sapiens	86.41	0.00e+00	1733.00
IUUC-Hvu-047303	Hordeum vulgare	33.59	1.00e-62	234.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	84.12	0.00e+00	1709.00
IUUC-Lch-049989	Latimeria chalumnae	75.84	0.00e+00	1539.00
IUUC-Lpe-051612	Leersia perrieri	32.95	7.00e-77	282.00
IUUC-Loc-052756	Lepisosteus oculatus	70.05	0.00e+00	1442.00
IUUC-Laf-054043	Loxodonta africana	85.18	0.00e+00	1726.00
IUUC-Mcc-054986	Macaca mulatta	84.74	0.00e+00	1710.00
IUUC-Meu-056228	Macropus eugenii	70.78	0.00e+00	773.00
IUUC-Mtr-058610	Medicago truncatula	30.59	7.00e-80	291.00
IUUC-Mvi-060269	Microbotryum violaceum	36.89	5.00e-62	233.00
IUUC-Mmr-060887	Microcebus murinus	86.21	0.00e+00	1729.00
IUUC-Mdo-062506	Monodelphis domestica	86.91	0.00e+00	1747.00
IUUC-Mmu-063642	Mus musculus	82.92	0.00e+00	1684.00
IUUC-Mac-064896	Musa acuminata	31.95	9.00e-77	281.00
IUUC-Mpu-066194	Mustela putorius furo	86.41	0.00e+00	1729.00
IUUC-Mlu-067233	Myotis lucifugus	86.03	0.00e+00	1731.00
IUUC-Nle-069052	Nomascus leucogenys	85.09	0.00e+00	1715.00
IUUC-Opr-070890	Ochotona princeps	85.37	0.00e+00	1031.00
IUUC-Ont-071450	Oreochromis niloticus	63.98	0.00e+00	1288.00
IUUC-Oan-073252	Ornithorhynchus anatinus	83.95	0.00e+00	979.00
IUUC-Ocu-073796	Oryctolagus cuniculus	85.70	0.00e+00	1555.00
IUUC-Oba-075563	Oryza barthii	29.60	4.00e-78	286.00
IUUC-Obr-076394	Oryza brachyantha	31.97	3.00e-77	283.00
IUUC-Ogl-077339	Oryza glaberrima	39.48	1.00e-38	153.00
IUUC-Ogu-079007	Oryza glumaepatula	34.55	7.00e-73	268.00
IUUC-Oin-079997	Oryza indica	29.60	3.00e-78	286.00
IUUC-Olo-080364	Oryza longistaminata	34.32	4.00e-78	286.00
IUUC-Ome-081165	Oryza meridionalis	33.27	5.00e-73	269.00
IUUC-Oni-083026	Oryza nivara	30.06	3.00e-78	286.00
IUUC-Opu-083284	Oryza punctata	35.09	2.00e-73	270.00
IUUC-Oru-084797	Oryza rufipogon	29.60	3.00e-78	286.00
IUUC-Osa-086221	Oryza sativa	39.48	1.00e-38	153.00
IUUC-Ola-086568	Oryzias latipes	66.38	0.00e+00	1364.00
IUUC-Oga-088687	Otolemur garnettii	85.40	0.00e+00	1719.00
IUUC-Oar-090345	Ovis aries	86.41	0.00e+00	1732.00
IUUC-Ptr-090734	Pan troglodytes	86.31	0.00e+00	1732.00
IUUC-Pan-091704	Papio anubis	83.03	0.00e+00	1644.00
IUUC-Psi-092937	Pelodiscus sinensis	92.12	0.00e+00	1675.00
IUUC-Ppa-095808	Physcomitrella patens	28.62	3.00e-67	250.00
IUUC-Pab-098129	Pongo abelii	86.31	0.00e+00	1732.00
IUUC-Pop-099494	Populus trichocarpa	30.37	1.00e-77	285.00
IUUC-Pca-100647	Procavia capensis	89.93	9.00e-156	544.00
IUUC-Ppe-102091	Prunus persica	29.00	2.00e-78	287.00
IUUC-Pva-102719	Pteropus vampyrus	86.11	0.00e+00	1720.00
IUUC-Rno-105363	Rattus norvegicus	84.82	0.00e+00	1710.00
IUUC-Sha-107620	Sarcophilus harrisii	84.44	0.00e+00	1714.00
IUUC-Smo-109487	Selaginella moellendorffii	27.55	1.00e-80	294.00
IUUC-Sit-110683	Setaria italica	30.13	5.00e-79	288.00
IUUC-Sly-111377	Solanum lycopersicum	29.67	1.00e-76	281.00
IUUC-Stu-111969	Solanum tuberosum	32.69	2.00e-67	249.00
IUUC-Sar-113099	Sorex araneus	86.30	0.00e+00	1559.00
IUUC-Sbi-113833	Sorghum bicolor	41.95	5.00e-55	207.00
IUUC-Ssc-115279	Sus scrofa	79.13	0.00e+00	1172.00
IUUC-Tgu-117519	Taeniopygia guttata	91.22	0.00e+00	1791.00
IUUC-Tru-117651	Takifugu rubripes	66.03	0.00e+00	1343.00
IUUC-Tsy-119201	Tarsius syrichta	83.87	0.00e+00	1619.00
IUUC-Tni-120840	Tetraodon nigroviridis	67.34	0.00e+00	1368.00
IUUC-Tca-121674	Theobroma cacao	28.12	3.00e-83	303.00
IUUC-Tae-125247	Triticum aestivum	28.54	9.00e-80	291.00
IUUC-Tur-126599	Triticum urartu	28.86	8.00e-79	288.00
IUUC-Tbe-127782	Tupaia belangeri	75.75	0.00e+00	1447.00
IUUC-Ttr-128312	Tursiops truncatus	84.82	0.00e+00	1694.00
IUUC-Vpa-130348	Vicugna pacos	86.09	0.00e+00	1720.00
IUUC-Vvi-131353	Vitis vinifera	32.96	1.00e-81	298.00
IUUC-Xtr-132172	Xenopus tropicalis	69.92	0.00e+00	1315.00
IUUC-Xma-133263	Xiphophorus maculatus	66.99	0.00e+00	1326.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence