iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093811

Ensembl Protein ID

ENSPSIP00000015042.1

UniProt Accession

K7G431; K7G431_PELSI

Genbank Protein ID

ENSPSIP00000015042

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01120427

Gene Name

WDR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000013318.1	ENSPSIT00000015113.1	ENSPSIP00000015042.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.70e-40	133.4	235	267
UBD/Beta-Prp	4.60e-63	213.2	57	282

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           H ++++++++ +d  +l+s+s+D+t k+WD+  
   Q: 235  HDGGIYAISWsPDsSHLLSASGDKTAKIWDVAA 267
           99*********999****************966 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlk 91
           ++h +++ + k++p++ ++a+g  +g++++wd+t++  l ++  +   ++++++ + +d+k l+ ++e   ++  v+  +tg+ v  ++
   Q: 57   TEHAHQVVVAKYAPSGFYIASGDISGKLRIWDTTQKEHLLKYeyQPFAGKIKDLAWTEDSKRLAVVGEGreKFGAVFLWDTGSSVGEIS 145
           4566667778*************************998777742334567****************99999777888888********* PP
   S: 92   ghedsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tg 177
           gh++ + s+++ +++ +++v+Gs+d+    ++ +  +    t s h ++vncv+++pdgn ++++s+D+++ ++d ktg+ +  l   +
   Q: 146  GHNKVINSVDIKQTRpYRIVTGSDDNCSAFFEGPPFKFKF-TISDHGRFVNCVKFSPDGNRFATSSADGQIFVYDGKTGEKICALggNK 233
           *************999****************99999998.********************************************9977 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvk 226
           +h++ +y +s+++++ +l+s+s d+t k+wd+ ++++v t+n  ++   
   Q: 234  AHDGGIYAISWSPDSSHLLSASGDKTAKIWDVAANSVVSTFNMGSNVLD 282
           7***************************************997665443 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

KALARGVENV FASLPQVERG VSKILGGDPK GNNFLYTNGK CVVIRNIDNP AIADIYTEHA 60
HQVVVAKYAP SGFYIASGDI SGKLRIWDTT QKEHLLKYEY QPFAGKIKDL AWTEDSKRLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGGCGCTGG CTCGGGGCGT AGAAAACGTG TTTGCCAGCC TGCCCCAGGT TGAAAGAGGT 60
GTCTCCAAAA TCCTTGGCGG GGATCCCAAG GGCAACAACT TTCTGTATAC CAATGGAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0030043--P:actin filament fragmentation
GO:0043297--P:apical junction assembly
GO:0030865--P:cortical cytoskeleton organization
GO:0042247--P:establishment of planar polarity of follicular epithelium
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0002446--P:neutrophil mediated immunity
GO:1990266--P:neutrophil migration
GO:0030220--P:platelet formation
GO:0030836--P:positive regulation of actin filament depolymerization
GO:0008360--P:regulation of cell shape
GO:0060307--P:regulation of ventricular cardiac muscle cell membrane repolarization
GO:0045214--P:sarcomere organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	34.79	4.00e-82	298.00
IUUC-Aml-002368	Ailuropoda melanoleuca	87.52	0.00e+00	1100.00
IUUC-Atr-003160	Amborella trichopoda	37.12	1.00e-113	403.00
IUUC-Apl-004012	Anas platyrhynchos	90.03	0.00e+00	1107.00
IUUC-Aca-004707	Anolis carolinensis	83.89	0.00e+00	1059.00
IUUC-Aly-006465	Arabidopsis lyrata	37.07	4.00e-110	391.00
IUUC-Ath-006740	Arabidopsis thaliana	37.07	2.00e-108	385.00
IUUC-Ago-007920	Ashbya gossypii	27.61	3.00e-74	272.00
IUUC-Acl-008262	Aspergillus clavatus	37.30	2.00e-107	382.00
IUUC-Afl-008471	Aspergillus flavus	32.83	1.00e-77	284.00
IUUC-Afu-008989	Aspergillus fumigatus	37.84	1.00e-95	343.00
IUUC-Ani-009167	Aspergillus nidulans	37.38	4.00e-114	405.00
IUUC-Ang-009595	Aspergillus niger	37.67	1.00e-102	367.00
IUUC-Aor-009908	Aspergillus oryzae	36.58	2.00e-101	362.00
IUUC-Ate-010580	Aspergillus terreus	37.56	1.00e-107	385.00
IUUC-Ame-011269	Astyanax mexicanus	60.86	2.00e-134	471.00
IUUC-Bgr-011996	Blumeria graminis	33.39	5.00e-106	378.00
IUUC-Bta-013278	Bos taurus	87.87	0.00e+00	1126.00
IUUC-Bci-013925	Botrytis cinerea	35.52	6.00e-108	384.00
IUUC-Bdi-014659	Brachypodium distachyon	35.63	5.00e-104	371.00
IUUC-Bol-016043	Brassica oleracea	35.77	3.00e-108	385.00
IUUC-Bra-017139	Brassica rapa	35.93	1.00e-108	387.00
IUUC-Cel-018417	Caenorhabditis elegans	40.07	2.00e-123	436.00
IUUC-Cja-019952	Callithrix jacchus	85.88	0.00e+00	1070.00
IUUC-Cfa-020225	Canis familiaris	86.88	0.00e+00	1095.00
IUUC-Cpo-021900	Cavia porcellus	86.86	0.00e+00	1102.00
IUUC-Csa-023028	Chlorocebus sabaeus	86.71	0.00e+00	1078.00
IUUC-Cho-025030	Choloepus hoffmanni	62.94	0.00e+00	703.00
IUUC-Cin-025152	Ciona intestinalis	53.57	8.00e-79	286.00
IUUC-Csv-025986	Ciona savignyi	35.97	7.00e-90	323.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	36.82	8.00e-109	387.00
IUUC-Cne-026814	Cryptococcus neoformans	34.42	3.00e-97	348.00
IUUC-Dre-027498	Danio rerio	81.68	8.00e-95	338.00
IUUC-Dno-029383	Dasypus novemcinctus	86.05	0.00e+00	1068.00
IUUC-Dor-030633	Dipodomys ordii	85.56	0.00e+00	1005.00
IUUC-Dse-031526	Dothistroma septosporum	38.05	4.00e-115	408.00
IUUC-Dme-031597	Drosophila melanogaster	47.51	8.00e-169	586.00
IUUC-Ete-032780	Echinops telfairi	80.64	0.00e+00	993.00
IUUC-Eca-034306	Equus caballus	85.00	0.00e+00	1058.00
IUUC-Eeu-034531	Erinaceus europaeus	69.16	2.00e-128	452.00
IUUC-Fca-036301	Felis catus	87.52	0.00e+00	1125.00
IUUC-Fal-037361	Ficedula albicollis	91.38	0.00e+00	1163.00
IUUC-Fox-037924	Fusarium oxysporum	34.32	6.00e-98	351.00
IUUC-Fso-038199	Fusarium solani	33.33	3.00e-93	335.00
IUUC-Gmo-039238	Gadus morhua	71.43	0.00e+00	895.00
IUUC-Ggr-039830	Gaeumannomyces graminis	34.91	3.00e-96	345.00
IUUC-Gga-040235	Gallus gallus	91.20	0.00e+00	1134.00
IUUC-Gac-042363	Gasterosteus aculeatus	70.68	0.00e+00	926.00
IUUC-Gma-044189	Glycine max	35.90	4.00e-112	398.00
IUUC-Ggo-044632	Gorilla gorilla	84.25	0.00e+00	1042.00
IUUC-Hsa-045792	Homo sapiens	86.21	0.00e+00	1089.00
IUUC-Hvu-047517	Hordeum vulgare	34.91	6.00e-108	384.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	87.35	0.00e+00	1095.00
IUUC-Kpa-049183	Komagataella pastoris	31.84	7.00e-87	314.00
IUUC-Lch-050428	Latimeria chalumnae	77.10	0.00e+00	1019.00
IUUC-Lpe-051306	Leersia perrieri	36.17	3.00e-109	389.00
IUUC-Loc-052096	Lepisosteus oculatus	71.10	0.00e+00	891.00
IUUC-Lma-053313	Leptosphaeria maculans	38.64	3.00e-118	421.00
IUUC-Laf-054060	Loxodonta africana	85.05	0.00e+00	1071.00
IUUC-Mcc-055619	Macaca mulatta	85.10	0.00e+00	1055.00
IUUC-Meu-056689	Macropus eugenii	76.65	1.00e-178	619.00
IUUC-Mor-056940	Magnaporthe oryzae	34.26	2.00e-95	342.00
IUUC-Mpo-057557	Magnaporthe poae	30.67	3.00e-70	259.00
IUUC-Mtr-058478	Medicago truncatula	35.02	2.00e-108	385.00
IUUC-Mla-059103	Melampsora laricipopulina	34.01	7.00e-81	294.00
IUUC-Mga-060150	Meleagris gallopavo	91.69	0.00e+00	1133.00
IUUC-Mvi-060448	Microbotryum violaceum	32.23	8.00e-78	284.00
IUUC-Mmr-061226	Microcebus murinus	85.05	0.00e+00	1068.00
IUUC-Mdo-062674	Monodelphis domestica	88.70	0.00e+00	1119.00
IUUC-Mmu-064170	Mus musculus	87.21	0.00e+00	1103.00
IUUC-Mac-065124	Musa acuminata	37.18	2.00e-113	402.00
IUUC-Mpu-066001	Mustela putorius furo	82.88	0.00e+00	1070.00
IUUC-Mlu-067253	Myotis lucifugus	87.35	0.00e+00	1102.00
IUUC-Nfi-068550	Neosartorya fischeri	38.07	3.00e-110	392.00
IUUC-Ncr-068948	Neurospora crassa	35.60	5.00e-112	398.00
IUUC-Nle-070115	Nomascus leucogenys	84.01	0.00e+00	980.00
IUUC-Opr-070254	Ochotona princeps	84.47	0.00e+00	1032.00
IUUC-Ont-071666	Oreochromis niloticus	73.59	0.00e+00	949.00
IUUC-Oan-073594	Ornithorhynchus anatinus	86.79	3.00e-159	553.00
IUUC-Ocu-074824	Oryctolagus cuniculus	84.72	0.00e+00	1043.00
IUUC-Oba-075010	Oryza barthii	36.17	5.00e-110	391.00
IUUC-Obr-076364	Oryza brachyantha	37.85	8.00e-112	397.00
IUUC-Ogl-077019	Oryza glaberrima	36.17	5.00e-110	391.00
IUUC-Ogu-078496	Oryza glumaepatula	36.17	5.00e-110	391.00
IUUC-Oin-080116	Oryza indica	36.33	4.00e-110	391.00
IUUC-Olo-080290	Oryza longistaminata	36.17	1.00e-109	390.00
IUUC-Ome-081969	Oryza meridionalis	36.17	6.00e-110	391.00
IUUC-Oni-082075	Oryza nivara	36.17	5.00e-110	391.00
IUUC-Opu-083959	Oryza punctata	36.33	2.00e-110	392.00
IUUC-Oru-084711	Oryza rufipogon	36.17	5.00e-110	391.00
IUUC-Osa-085958	Oryza sativa	36.33	4.00e-110	391.00
IUUC-Ola-086968	Oryzias latipes	73.75	0.00e+00	956.00
IUUC-Oga-089108	Otolemur garnettii	85.83	0.00e+00	1114.00
IUUC-Oar-089986	Ovis aries	82.95	0.00e+00	1055.00
IUUC-Ptr-091281	Pan troglodytes	86.81	0.00e+00	1090.00
IUUC-Pan-092585	Papio anubis	86.54	0.00e+00	1075.00
IUUC-Pma-094542	Petromyzon marinus	69.23	0.00e+00	903.00
IUUC-Pno-095086	Phaeosphaeria nodorum	36.74	5.00e-109	388.00
IUUC-Ppa-095876	Physcomitrella patens	35.48	1.00e-110	393.00
IUUC-Pfo-096973	Poecilia formosa	74.09	0.00e+00	983.00
IUUC-Pab-098391	Pongo abelii	86.05	0.00e+00	1073.00
IUUC-Pop-098850	Populus trichocarpa	36.66	2.00e-110	392.00
IUUC-Pca-100257	Procavia capensis	56.29	8.00e-86	311.00
IUUC-Ppe-101578	Prunus persica	36.82	3.00e-111	395.00
IUUC-Pva-102872	Pteropus vampyrus	81.59	0.00e+00	1045.00
IUUC-Pgr-103593	Puccinia graminis	33.94	9.00e-83	300.00
IUUC-Pte-104365	Pyrenophora teres	38.83	2.00e-111	396.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	38.50	5.00e-114	404.00
IUUC-Rno-105737	Rattus norvegicus	87.71	0.00e+00	1122.00
IUUC-Sce-106383	Saccharomyces cerevisiae	28.98	7.00e-70	258.00
IUUC-Sha-107084	Sarcophilus harrisii	86.63	0.00e+00	989.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	35.55	2.00e-113	402.00
IUUC-Spo-108309	Schizosaccharomyces pombe	31.43	2.00e-93	336.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	35.52	4.00e-108	385.00
IUUC-Smo-109255	Selaginella moellendorffii	35.18	3.00e-103	369.00
IUUC-Sit-109962	Setaria italica	37.40	5.00e-113	401.00
IUUC-Sly-110897	Solanum lycopersicum	38.86	1.00e-113	403.00
IUUC-Stu-111971	Solanum tuberosum	38.54	3.00e-112	398.00
IUUC-Sar-113415	Sorex araneus	69.74	5.00e-108	384.00
IUUC-Sbi-114857	Sorghum bicolor	36.91	1.00e-110	393.00
IUUC-Sre-114900	Sporisorium reilianum	35.66	1.00e-95	343.00
IUUC-Tgu-117256	Taeniopygia guttata	91.36	0.00e+00	1165.00
IUUC-Tru-117871	Takifugu rubripes	69.77	0.00e+00	900.00
IUUC-Tsy-119172	Tarsius syrichta	89.58	5.00e-132	464.00
IUUC-Tni-120339	Tetraodon nigroviridis	70.43	0.00e+00	927.00
IUUC-Tca-121563	Theobroma cacao	36.20	4.00e-109	388.00
IUUC-Tre-122076	Trichoderma reesei	35.47	1.00e-94	340.00
IUUC-Tvi-122528	Trichoderma virens	34.10	5.00e-96	344.00
IUUC-Tae-124549	Triticum aestivum	35.18	2.00e-108	386.00
IUUC-Tur-126845	Triticum urartu	34.76	2.00e-80	293.00
IUUC-Tme-127217	Tuber melanosporum	35.60	4.00e-106	378.00
IUUC-Tbe-127526	Tupaia belangeri	84.41	0.00e+00	1068.00
IUUC-Ttr-128898	Tursiops truncatus	79.27	0.00e+00	1006.00
IUUC-Uma-129631	Ustilago maydis	33.12	2.00e-95	343.00
IUUC-Vda-129732	Verticillium dahliae	34.29	3.00e-90	325.00
IUUC-Vvi-131217	Vitis vinifera	37.25	3.00e-111	395.00
IUUC-Xtr-132860	Xenopus tropicalis	72.74	0.00e+00	931.00
IUUC-Xma-133830	Xiphophorus maculatus	73.92	0.00e+00	981.00
IUUC-Yli-134335	Yarrowia lipolytica	33.28	6.00e-75	275.00
IUUC-Zma-135907	Zea mays	37.07	3.00e-111	395.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence