iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007224

UUCD1 version

UUC-ArT-01589

Ensembl Protein ID

AT3G08690.2

UniProt Accession

P35134; Q4TYZ9; Q9M9J1; UBC11_ARATH

Genbank Protein ID

AAY44851.1; AAG51362.1; AEE74664.1; AEE74665.1; AAL36225.1; AAM14162.1; AAM63316.1; BAF00202.1; CAA78716.1; AAA32896.1

Protein Name

Ubiquitin-conjugating enzyme E2 11; E2 ubiquitin-conjugating enzyme 11; Ubiquitin carrier protein 11; Ubiquitin-conjugating enzyme E2-17 kDa 11; Ubiquitin-protein ligase 11

Genbank Nucleotide ID

DQ027025; AC012562; CP002686; CP002686; AY063869; AY091223; AY086109; AK228254; Z14992; L00641

Gene Name

UBC11; At3g08690; F17O14.16

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G08690	AT3G08690.2	AT3G08690.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
PINA	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E2/UBC	E2_UBC	20435904; 18643997; 16339806

Classification

Family	E-value	Score	Start	End
E2/UBC	1.10e-56	191.4	5	139
UBD/UBC-like/UBD_UBC	6.10e-74	247.5	5	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsv 98
           R+ kelk+l+kdpp+++sa+pv e d+++w+++i+Gp+++pY+ggvF ++i+fp+dYPfkPPkv+f tk++hPn+++nG++Cl+ilk  e+Wspal++
   Q: 5    RILKELKDLQKDPPSNCSAGPVAE-DMFHWQATIMGPPESPYAGGVFLVSIHFPPDYPFKPPKVSFKTKVYHPNINSNGSICLDILK--EQWSPALTI 99
           899*********************.9************************************************************9..********* PP
   S: 99   esvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++vllsi+sll++pnp++pl  e+a+++k++r++y++++r
   Q: 100  SKVLLSICSLLTDPNPDDPLVPEIAHMYKTDRSKYESTAR 139
           ************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaaltlskv 98
           ri kelkdl++d+++++sa++v +d+f+++ati+gpp+spy ggvf + i++p dypfkppkv+f tk+yhpninsngsicldil++qws+alt+skv
   Q: 5    RILKELKDLQKDPPSNCSAGPVAEDMFHWQATIMGPPESPYAGGVFLVSIHFPPDYPFKPPKVSFKTKVYHPNINSNGSICLDILKEQWSPALTISKV 102
           899*********************************************************************************************** PP
   S: 99   llslcslladaepddplvaeiariyktdkekykriarewt 138
           lls+csll+d++pddplv+eia++yktd+ ky+ +ar wt
   Q: 103  LLSICSLLTDPNPDDPLVPEIAHMYKTDRSKYESTARSWT 142
           ***************************************8 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins.

Protein Sequence
(Fasta)

MASKRILKEL KDLQKDPPSN CSAGPVAEDM FHWQATIMGP PESPYAGGVF LVSIHFPPDY 60
PFKPPKVSFK TKVYHPNINS NGSICLDILK EQWSPALTIS KVLLSICSLL TDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTGCTGAT AGAATCAGAA GCTTCGAGAC TGACTTGTTT TAGATTCTCT GACTATAAAG 60
AAAGGCAAAG TAACAAGTTT CGTTTTCTCC TTTGCACTCC ATTTTTATTC TCGATTCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ath:AT3G08690

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000292	Aegilops tauschii	94.59	2.00e-82	297.00
IUUC-Aml-001563	Ailuropoda melanoleuca	76.19	1.00e-68	251.00
IUUC-Aly-006542	Arabidopsis lyrata	100.00	9.00e-86	307.00
IUUC-Ago-007967	Ashbya gossypii	78.91	4.00e-71	259.00
IUUC-Afl-008709	Aspergillus flavus	77.86	3.00e-69	255.00
IUUC-Ani-009401	Aspergillus nidulans	79.59	4.00e-71	259.00
IUUC-Aor-010157	Aspergillus oryzae	80.27	6.00e-72	261.00
IUUC-Bgr-012238	Blumeria graminis	81.63	1.00e-71	260.00
IUUC-Bci-013661	Botrytis cinerea	80.95	2.00e-72	263.00
IUUC-Bdi-014832	Brachypodium distachyon	94.59	2.00e-82	296.00
IUUC-Bol-015583	Brassica oleracea	97.97	1.00e-84	303.00
IUUC-Bra-017581	Brassica rapa	97.97	1.00e-84	303.00
IUUC-Cel-018362	Caenorhabditis elegans	79.59	8.00e-71	258.00
IUUC-Csa-023668	Chlorocebus sabaeus	76.19	1.00e-68	251.00
IUUC-Cho-024987	Choloepus hoffmanni	76.19	1.00e-68	251.00
IUUC-Cgl-026490	Colletotrichum gloeosporioides	80.27	5.00e-72	262.00
IUUC-Cme-027220	Cyanidioschyzon merolae	80.95	2.00e-71	260.00
IUUC-Dno-030067	Dasypus novemcinctus	76.19	1.00e-68	251.00
IUUC-Dor-030323	Dipodomys ordii	80.27	9.00e-71	258.00
IUUC-Dse-031397	Dothistroma septosporum	79.59	1.00e-71	261.00
IUUC-Ete-032540	Echinops telfairi	76.19	1.00e-68	251.00
IUUC-Eca-034167	Equus caballus	76.19	1.00e-68	251.00
IUUC-Fox-038021	Fusarium oxysporum	80.27	1.00e-71	260.00
IUUC-Fso-038297	Fusarium solani	80.95	4.00e-72	262.00
IUUC-Ggr-039912	Gaeumannomyces graminis	76.32	9.00e-68	248.00
IUUC-Gac-042516	Gasterosteus aculeatus	79.59	1.00e-69	254.00
IUUC-Itr-048743	Ictidomys tridecemlineatus	76.19	1.00e-68	251.00
IUUC-Lpe-051194	Leersia perrieri	93.92	4.00e-82	296.00
IUUC-Lma-053121	Leptosphaeria maculans	80.27	4.00e-72	262.00
IUUC-Mor-057235	Magnaporthe oryzae	80.95	7.00e-72	261.00
IUUC-Mpo-057596	Magnaporthe poae	75.66	2.00e-67	246.00
IUUC-Mpu-065724	Mustela putorius furo	76.19	1.00e-68	251.00
IUUC-Mlu-067573	Myotis lucifugus	75.71	9.00e-66	241.00
IUUC-Ncr-068677	Neurospora crassa	79.59	6.00e-71	258.00
IUUC-Ont-072345	Oreochromis niloticus	78.91	3.00e-70	256.00
IUUC-Oba-075924	Oryza barthii	93.92	9.00e-82	294.00
IUUC-Obr-076481	Oryza brachyantha	93.92	1.00e-81	294.00
IUUC-Ogu-078581	Oryza glumaepatula	93.92	9.00e-82	294.00
IUUC-Ome-081967	Oryza meridionalis	93.92	1.00e-81	294.00
IUUC-Oni-082445	Oryza nivara	93.92	9.00e-82	294.00
IUUC-Osa-085585	Oryza sativa	93.92	7.00e-82	295.00
IUUC-Oga-088915	Otolemur garnettii	76.19	1.00e-68	251.00
IUUC-Pno-094765	Phaeosphaeria nodorum	80.27	4.00e-72	262.00
IUUC-Pca-100678	Procavia capensis	76.19	1.00e-68	251.00
IUUC-Pva-102770	Pteropus vampyrus	76.19	1.00e-68	251.00
IUUC-Ptt-103723	Puccinia triticina	77.86	2.00e-62	230.00
IUUC-Sha-106489	Sarcophilus harrisii	75.71	6.00e-66	241.00
IUUC-Sja-107729	Schizosaccharomyces japonicus	80.95	1.00e-71	261.00
IUUC-Spo-108032	Schizosaccharomyces pombe	81.63	5.00e-72	262.00
IUUC-Ssl-108443	Sclerotinia sclerotiorum	80.27	4.00e-72	262.00
IUUC-Sbi-114257	Sorghum bicolor	94.59	7.00e-82	295.00
IUUC-Tsy-118832	Tarsius syrichta	78.91	3.00e-68	249.00
IUUC-Tre-122125	Trichoderma reesei	80.27	1.00e-70	257.00
IUUC-Tvi-122296	Trichoderma virens	80.27	1.00e-70	257.00
IUUC-Tae-125784	Triticum aestivum	94.59	3.00e-82	296.00
IUUC-Tur-126518	Triticum urartu	94.59	2.00e-83	300.00
IUUC-Tme-126912	Tuber melanosporum	78.23	2.00e-70	256.00
IUUC-Tbe-127329	Tupaia belangeri	70.71	2.00e-61	226.00
IUUC-Ttr-128363	Tursiops truncatus	76.19	1.00e-68	251.00
IUUC-Vda-129695	Verticillium dahliae	80.27	5.00e-72	262.00
IUUC-Xma-133673	Xiphophorus maculatus	80.27	2.00e-70	256.00
IUUC-Yli-134353	Yarrowia lipolytica	76.19	2.00e-69	253.00
IUUC-Zma-135569	Zea mays	94.59	5.00e-82	295.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence