iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007554

UUCD1 version

UUC-ArT-01531

Ensembl Protein ID

AT5G58550.1

UniProt Accession

Q9LV01; F4KF02; Q0WQF6; Q6PWY1; ETOL2_ARATH

Genbank Protein ID

AAT01658.1; BAA97325.1; AED97067.1; BAF00643.1

Protein Name

ETO1-like protein 2; Ethylene overproducer 1-like protein 2

Genbank Nucleotide ID

AY572793; AB020755; AB025632; AK228743

Gene Name

EOL2; At5g58550; MQJ2; MZN1.1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G58550	AT5G58550.1	AT5G58550.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
Mentha
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/BCR/BTB_Other	BTB_Other	18808454

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.30e-10	42.4	207	275

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd..vqpevfrallkFlYtgklden 68
           +D+ ++vg e+ ++ ++ +aa S++F+a++++ + es+ ++++++++  ++ e++ al  +++ +++d++
   Q: 207  SDISFCVGSEKAKCVRSRIAALSRPFEAMLYGSFVEST-TSEIDFSEngISIEAMLALNIYSRIKRVDLF 275
           69***********************************9.*******668*****************9985 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Potential regulator of the ethylene pathway, which acts by regulating the stability of 1-aminocyclopropane-1-carboxylate synthase (ACS) enzymes. May act as a substrate-specific adapter that connects ACS enzymes, such as ACS5, to ubiquitin ligase complexes, leading to proteasomal degradation of ACS enzymes (By similarity).

Protein Sequence
(Fasta)

MRNLKLFERF KSTQVHAFTT QDSPSTSSNG SPRMMKFLGH PKSKSRSLLP HGFPTTDLLE 60
PPLDSYLKPI DLVESLSNLY RRIESSSESE ASMLYLEQYA VLRSLGDAKL LRRCLLNARR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAATAAGAA CCACCAACTG TTGAAGTTCG TAAACTGTTC CACAAAAAAA TGCATAAAAG 60
AAAGAAAAAC AGATATGAGA TTCGACCATT TTTTTTCCAT ATAAATGTTT TTTGGGTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0936--Ethylene signaling pathway
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
KW-0833--Ubl conjugation pathway

Interpro

IPR000210--BTB/POZ_dom
IPR023114--Elongated_TPR_rpt_dom
IPR011333--SKP1/BTB/POZ
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat

PROSITE

PS50005--TPR
PS50293--TPR_REGION

Pfam

PF00651--BTB
PF13181--TPR_8

SMART

SM00225--BTB
SM00028--TPR

Gene Ontology

GO:0005622--C:intracellular
GO:0009873--P:ethylene-activated signaling pathway
GO:0016567--P:protein ubiquitination

KEGG

ath:AT5G58550

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005894	Arabidopsis lyrata	96.11	0.00e+00	1796.00
IUUC-Bol-016029	Brassica oleracea	84.19	0.00e+00	1522.00
IUUC-Bra-018010	Brassica rapa	84.15	0.00e+00	1512.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence