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Tag Content
UUCD2 ID IUUC-Itr-048275
UUCD1 version UUC-SpT-00339
Ensembl Protein ID ENSSTOP00000001412.2
UniProt Accession I3LYU5; I3LYU5_ICTTR
Genbank Protein ID ENSSTOP00000001412
Protein Name Ribosome biogenesis protein WDR12; WD repeat-containing protein 12
Genbank Nucleotide ID AGTP01099869
Gene Name WDR12
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSTOG00000001578.2 ENSSTOT00000001578.2 ENSSTOP00000001412.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 6.10e-44 146.1 255 290
UBD/Beta-Prp 1.00e-45 156.2 246 412
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvl 35
           gHt+ ++++ +sd   ++s+s+D+tikvWD+ +g l
   Q: 255  GHTEAISSVLWSDaEEICSASWDHTIKVWDVESGGL 290
           8**********999*****************99976 PP
   

   UBD/Beta-Prp
   S: 83   tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..ktg 169
           t+++++tl+gh++ + s+ +s   + + s+s+d ti+vwd+e+g   + tl+g++ v nc++++p ++ l+sGs+Dr +rlWd   k g
   Q: 246  TRTPMVTLSGHTEAISSVLWSD-AEEICSASWDHTIKVWDVESGGLKS-TLTGNK-VFNCISYSPLCKRLASGSTDRHIRLWDPrtKDG 331
           567899***************9.99**********************9.***987.99**************************54456 PP
   S: 170  kllrtl.tgghtdsvyslsfdsng.kelvsgsldgtvklwdlq.tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           +l+    t+ ht+ v+ ++++++  ++l+sgsld+ vklwd +  +  ++ l +h+d v+sv+ + ++ +l+sg++D+ ++ +
   Q: 332  SLVSLSlTS-HTGWVTAVKWSPTHeQQLISGSLDNIVKLWDTRsCKAPLYDLAAHEDKVLSVDWT-DTGLLLSGGADNKLYSY 412
           666644366.************9889*****************54566****************9.999********998765 PP
   
Organism Ictidomys tridecemlineatus
Functional Description
(View)

Functional Description


     Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
 Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Protein Sequence
(Fasta)
MAQLQTRFFT DNKKYVVDDV PFSIPATSEI ADLSNIINKL LEAKNEFHKH VEFDFLIKGQ 60
FLRMPLFKHM ELENISSEEV VELEYVEKYT APQPEQCMFH DDWISSIKGA EEWILTGSYD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Itr-048275|E3,WD_repeat;UBD,Beta-Prp|Ictidomys tridecemlineatus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGCTCAGC TCCAGACACG CTTCTTCACT GACAACAAGA AGTAAGTAAG CGGCCCAGCC 60
GTCGGGATTA GCTTCTTTCC CAGGCACGAC CTTGTGTTCT TGTTTTCCCC TGATTGTCAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Itr-048275|E3,WD_repeat;UBD,Beta-Prp|Ictidomys tridecemlineatus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08154--NLE
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005654--C:nucleoplasm
GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0008283--P:cell proliferation
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0007219--P:Notch signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000532 Aegilops tauschii 33.25 6.00e-57 214.00
IUUC-Aml-001997 Ailuropoda melanoleuca 95.85 0.00e+00 743.00
IUUC-Atr-002544 Amborella trichopoda 32.86 3.00e-55 208.00
IUUC-Apl-003981 Anas platyrhynchos 87.50 0.00e+00 650.00
IUUC-Aca-004370 Anolis carolinensis 85.41 0.00e+00 707.00
IUUC-Aly-006455 Arabidopsis lyrata 34.73 2.00e-58 219.00
IUUC-Ath-006669 Arabidopsis thaliana 33.91 4.00e-54 204.00
IUUC-Ago-007864 Ashbya gossypii 30.39 4.00e-37 148.00
IUUC-Acl-008177 Aspergillus clavatus 28.13 3.00e-34 139.00
IUUC-Afl-008617 Aspergillus flavus 28.21 1.00e-33 137.00
IUUC-Afu-008752 Aspergillus fumigatus 28.21 2.00e-31 129.00
IUUC-Ani-009136 Aspergillus nidulans 29.23 5.00e-34 138.00
IUUC-Ang-009701 Aspergillus niger 27.18 9.00e-32 131.00
IUUC-Aor-009884 Aspergillus oryzae 28.46 3.00e-33 135.00
IUUC-Ate-010472 Aspergillus terreus 28.69 1.00e-20 93.60
IUUC-Ame-011432 Astyanax mexicanus 75.41 0.00e+00 649.00
IUUC-Bgr-012218 Blumeria graminis 27.65 9.00e-30 124.00
IUUC-Bta-012829 Bos taurus 96.45 0.00e+00 775.00
IUUC-Bci-013953 Botrytis cinerea 29.53 3.00e-34 139.00
IUUC-Bdi-014351 Brachypodium distachyon 36.02 5.00e-56 211.00
IUUC-Bol-016190 Brassica oleracea 34.03 3.00e-53 202.00
IUUC-Bra-017876 Brassica rapa 33.50 1.00e-55 210.00
IUUC-Cel-018569 Caenorhabditis elegans 32.77 1.00e-49 190.00
IUUC-Cja-019468 Callithrix jacchus 95.51 0.00e+00 751.00
IUUC-Cfa-020471 Canis familiaris 95.27 0.00e+00 744.00
IUUC-Cpo-022260 Cavia porcellus 95.98 0.00e+00 756.00
IUUC-Cre-022614 Chlamydomonas reinhardtii 30.96 9.00e-39 154.00
IUUC-Csa-023989 Chlorocebus sabaeus 95.74 0.00e+00 755.00
IUUC-Cho-024426 Choloepus hoffmanni 91.75 7.00e-158 549.00
IUUC-Cin-025789 Ciona intestinalis 43.65 4.00e-97 347.00
IUUC-Cne-027063 Cryptococcus neoformans 23.31 3.00e-20 92.80
IUUC-Dre-027907 Danio rerio 76.83 0.00e+00 669.00
IUUC-Dno-029225 Dasypus novemcinctus 94.33 0.00e+00 760.00
IUUC-Dor-031082 Dipodomys ordii 78.96 4.00e-169 587.00
IUUC-Dse-031308 Dothistroma septosporum 28.05 6.00e-35 141.00
IUUC-Dme-032189 Drosophila melanogaster 41.50 1.00e-92 332.00
IUUC-Ete-032247 Echinops telfairi 87.94 0.00e+00 703.00
IUUC-Eca-034285 Equus caballus 95.74 0.00e+00 768.00
IUUC-Eeu-035322 Erinaceus europaeus 84.67 0.00e+00 641.00
IUUC-Fca-036114 Felis catus 95.74 0.00e+00 769.00
IUUC-Fal-036891 Ficedula albicollis 86.44 4.00e-174 603.00
IUUC-Fox-037965 Fusarium oxysporum 25.37 1.00e-33 137.00
IUUC-Fso-038244 Fusarium solani 26.44 3.00e-32 132.00
IUUC-Gmo-039040 Gadus morhua 74.47 0.00e+00 664.00
IUUC-Gga-040610 Gallus gallus 83.92 0.00e+00 711.00
IUUC-Gac-042117 Gasterosteus aculeatus 74.94 0.00e+00 652.00
IUUC-Gma-043146 Glycine max 36.93 2.00e-65 243.00
IUUC-Ggo-045179 Gorilla gorilla 95.27 0.00e+00 746.00
IUUC-Hsa-046114 Homo sapiens 95.98 0.00e+00 752.00
IUUC-Hvu-047331 Hordeum vulgare 33.85 2.00e-52 199.00
IUUC-Kpa-049304 Komagataella pastoris 28.89 2.00e-40 159.00
IUUC-Lch-050655 Latimeria chalumnae 76.42 7.00e-143 499.00
IUUC-Lpe-051675 Leersia perrieri 35.32 2.00e-58 219.00
IUUC-Loc-052868 Lepisosteus oculatus 80.85 0.00e+00 670.00
IUUC-Lma-053258 Leptosphaeria maculans 26.35 2.00e-30 128.00
IUUC-Laf-053993 Loxodonta africana 93.85 0.00e+00 763.00
IUUC-Mcc-055128 Macaca mulatta 78.72 6.00e-172 596.00
IUUC-Meu-056501 Macropus eugenii 78.02 2.00e-160 558.00
IUUC-Mor-057114 Magnaporthe oryzae 25.56 9.00e-26 110.00
IUUC-Mtr-058367 Medicago truncatula 35.97 6.00e-59 221.00
IUUC-Mla-059107 Melampsora laricipopulina 26.57 7.00e-28 118.00
IUUC-Mga-059745 Meleagris gallopavo 82.12 0.00e+00 688.00
IUUC-Mvi-060362 Microbotryum violaceum 29.57 3.00e-34 139.00
IUUC-Mdo-062257 Monodelphis domestica 84.96 0.00e+00 714.00
IUUC-Mmu-063546 Mus musculus 94.33 0.00e+00 763.00
IUUC-Mac-065540 Musa acuminata 34.47 3.00e-54 205.00
IUUC-Mpu-066284 Mustela putorius furo 96.69 0.00e+00 776.00
IUUC-Mlu-067241 Myotis lucifugus 95.51 0.00e+00 766.00
IUUC-Nfi-068260 Neosartorya fischeri 27.95 5.00e-33 135.00
IUUC-Ncr-068719 Neurospora crassa 25.68 3.00e-25 109.00
IUUC-Nle-068981 Nomascus leucogenys 95.74 0.00e+00 732.00
IUUC-Opr-071218 Ochotona princeps 86.43 0.00e+00 662.00
IUUC-Ont-071646 Oreochromis niloticus 77.35 0.00e+00 672.00
IUUC-Oan-073453 Ornithorhynchus anatinus 89.83 0.00e+00 760.00
IUUC-Ocu-074008 Oryctolagus cuniculus 96.22 0.00e+00 771.00
IUUC-Oba-075712 Oryza barthii 31.01 7.00e-42 164.00
IUUC-Obr-076721 Oryza brachyantha 34.76 5.00e-58 218.00
IUUC-Ogl-077229 Oryza glaberrima 34.84 2.00e-57 216.00
IUUC-Ogu-078977 Oryza glumaepatula 31.01 4.00e-42 165.00
IUUC-Oin-079683 Oryza indica 34.84 9.00e-58 217.00
IUUC-Olo-080291 Oryza longistaminata 30.85 4.00e-28 118.00
IUUC-Ome-081834 Oryza meridionalis 35.08 2.00e-58 219.00
IUUC-Oni-082507 Oryza nivara 33.73 1.00e-53 203.00
IUUC-Opu-083396 Oryza punctata 34.61 5.00e-58 218.00
IUUC-Oru-085220 Oryza rufipogon 33.97 1.00e-53 203.00
IUUC-Osa-085767 Oryza sativa 34.84 9.00e-58 217.00
IUUC-Ola-087420 Oryzias latipes 76.83 0.00e+00 664.00
IUUC-Olu-087740 Ostreococcus lucimarinus 27.88 3.00e-36 145.00
IUUC-Oga-088264 Otolemur garnettii 95.04 0.00e+00 747.00
IUUC-Oar-089335 Ovis aries 95.98 0.00e+00 771.00
IUUC-Ptr-091320 Pan troglodytes 95.98 0.00e+00 752.00
IUUC-Pan-092833 Papio anubis 95.27 0.00e+00 750.00
IUUC-Psi-093504 Pelodiscus sinensis 87.47 0.00e+00 734.00
IUUC-Pma-094189 Petromyzon marinus 67.69 1.00e-168 585.00
IUUC-Pno-094929 Phaeosphaeria nodorum 25.93 4.00e-31 129.00
IUUC-Ppa-095429 Physcomitrella patens 35.70 1.00e-64 239.00
IUUC-Pfo-096337 Poecilia formosa 74.94 0.00e+00 669.00
IUUC-Pab-097571 Pongo abelii 95.74 0.00e+00 751.00
IUUC-Pop-099977 Populus trichocarpa 35.58 3.00e-63 235.00
IUUC-Pca-100394 Procavia capensis 88.51 0.00e+00 665.00
IUUC-Ppe-101848 Prunus persica 34.86 4.00e-59 221.00
IUUC-Pva-102921 Pteropus vampyrus 95.55 8.00e-115 406.00
IUUC-Pgr-103637 Puccinia graminis 28.60 5.00e-33 135.00
IUUC-Ptt-103781 Puccinia triticina 28.60 6.00e-33 134.00
IUUC-Pte-104135 Pyrenophora teres 25.36 3.00e-31 130.00
IUUC-Pyt-104609 Pyrenophora triticirepentis 24.67 1.00e-29 124.00
IUUC-Rno-105114 Rattus norvegicus 93.85 0.00e+00 761.00
IUUC-Sce-106401 Saccharomyces cerevisiae 29.96 9.00e-40 157.00
IUUC-Sha-107122 Sarcophilus harrisii 85.40 0.00e+00 685.00
IUUC-Sja-107766 Schizosaccharomyces japonicus 32.01 2.00e-47 182.00
IUUC-Spo-108134 Schizosaccharomyces pombe 29.59 1.00e-38 154.00
IUUC-Ssl-108398 Sclerotinia sclerotiorum 28.76 8.00e-35 141.00
IUUC-Smo-108720 Selaginella moellendorffii 33.33 1.00e-56 213.00
IUUC-Sit-110311 Setaria italica 35.81 4.00e-56 211.00
IUUC-Sly-111178 Solanum lycopersicum 33.58 2.00e-55 209.00
IUUC-Stu-112778 Solanum tuberosum 35.32 7.00e-60 224.00
IUUC-Sar-113596 Sorex araneus 78.01 2.00e-173 601.00
IUUC-Sbi-114193 Sorghum bicolor 35.48 1.00e-57 216.00
IUUC-Sre-115002 Sporisorium reilianum 24.14 1.00e-10 60.80
IUUC-Ssc-116066 Sus scrofa 96.45 0.00e+00 772.00
IUUC-Tgu-117048 Taeniopygia guttata 85.11 0.00e+00 639.00
IUUC-Tsy-119573 Tarsius syrichta 61.72 4.00e-129 454.00
IUUC-Tni-119820 Tetraodon nigroviridis 76.01 0.00e+00 669.00
IUUC-Tca-121605 Theobroma cacao 36.30 7.00e-61 227.00
IUUC-Tre-121947 Trichoderma reesei 26.50 1.00e-33 137.00
IUUC-Tvi-122481 Trichoderma virens 26.71 5.00e-35 141.00
IUUC-Tae-125861 Triticum aestivum 33.49 5.00e-57 214.00
IUUC-Tur-126586 Triticum urartu 34.10 1.00e-54 206.00
IUUC-Tme-126900 Tuber melanosporum 31.91 2.00e-48 186.00
IUUC-Tbe-127736 Tupaia belangeri 73.12 3.00e-152 530.00
IUUC-Ttr-129041 Tursiops truncatus 83.92 0.00e+00 659.00
IUUC-Uma-129628 Ustilago maydis 24.29 3.00e-11 63.20
IUUC-Vpa-130260 Vicugna pacos 96.22 0.00e+00 771.00
IUUC-Vvi-131009 Vitis vinifera 34.52 9.00e-59 220.00
IUUC-Xtr-132083 Xenopus tropicalis 81.09 0.00e+00 672.00
IUUC-Xma-133094 Xiphophorus maculatus 74.00 0.00e+00 664.00
IUUC-Yli-134531 Yarrowia lipolytica 22.93 2.00e-18 87.00
IUUC-Zma-135509 Zea mays 34.05 3.00e-58 218.00
Created Date 25-Jun-2017

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