iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003988

Ensembl Protein ID

ENSAPLP00000011939.1

UniProt Accession

U3IXG3; U3IXG3_ANAPL

Genbank Protein ID

ENSAPLP00000011939

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01051635

Gene Name

USP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000012121.1	ENSAPLT00000012671.1	ENSAPLP00000011939.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.90e-71	240.7	406	786

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l+++  +   ++++++ +++++++s+ +l++e++      k k+              a++p+
   Q: 406  GLINKGNWCYINATLQALVACPPMYHLMKS-IPMY-SKSQRPCTSTPMIDSFVRLMNEFTnmpvppKAKQAlgekivrdirpgaAFEPT 492
           9*****************************.3333.34455899***************7777664333337788888999999***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk..................eknkpkeeeeeedkselsde........aeek 133
            +++ l  +++++s + +q+Da+E+l f+l++l+ee+                    e+++  eeee++++ e s++        +   
   Q: 493  YIYRLLTVIKSSLSeKGRQEDAEEYLGFILNGLHEEMLTlkkllsphnekltvsngpEAQTVHEEEEQDEQGEGSEDeweqvgprN--- 578
           *9999999999966599********************4455688888888887777644444444444444444444455555552... PP
   S: 134  kkkknk...........slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekc 211
                k           ++i+d+F+g+++ +++ ++  ++s + +pf++l+l++++++ +   ++qd+Les +++e+++g    y++k 
   Q: 579  -----KssvtrqadfvqTPITDIFGGHISRSVVYQQSSKESATLQPFFTLQLDIQSDKIR---TVQDALESLVARESVQG----YTTKT 655
           .....444455555666*****************************************99...****************8....99999 PP
   S: 212  kkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...kkkYeLiavvvHsG.slssGHYv 296
           k+++e +++++l++lP+vL+lhLkRf ++++++++ k+ k++e+p  L++s+ + sp  k+k    +++Y+L+avv+H+G s+ +GHY+
   Q: 656  KQEVEISRRVTLEELPPVLVLHLKRFVYEKTGGCQ-KLIKNIEYPVDLEISKELLSPGVKSKIfkgQRTYRLFAVVYHHGnSATGGHYT 743
           ****************************9998886.****************99998877766888*********************** PP
   S: 297  ayvknekgk.WllfdDskVtevkeeevleetg.staYvlfYkr 337
           ++v +   + Wl++dD+ V+++++ +v++ ++ +taY+l+Y+r
   Q: 744  TDVFQIGLNgWLRIDDQAVKVINQYQVVKPSAeRTAYLLYYRR 786
           *****87777*****************998778********98 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

CGLLMTQYIF GEFSPDEFNQ FFVTPRCSVE LPPYNETVTC GIKSTGKCHH GEEYQRIEFG 60
VNEVIETESS VLNNTDYSIS STLNPQAPEF ILSCAPTQKT PDDSLRETNY NSIDCQFSDP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTGGTTTGC TAATGACTCA GGAAAAGTGG AGACTGGGAT GCAAACAGGT GAGATTCTGG 60
CTTCCAACAC ACGGGTCATT ATGATTGCCA ATGTCTTTAC TATGAATTTA TTAATTGCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF07145--PAM2
PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071347--P:cellular response to interleukin-1
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	31.23	1.00e-46	181.00
IUUC-Aml-001584	Ailuropoda melanoleuca	76.72	0.00e+00	1155.00
IUUC-Atr-002927	Amborella trichopoda	34.53	4.00e-58	219.00
IUUC-Aca-004461	Anolis carolinensis	96.42	3.00e-172	597.00
IUUC-Aly-006038	Arabidopsis lyrata	34.44	2.00e-54	206.00
IUUC-Ath-007328	Arabidopsis thaliana	34.18	6.00e-53	201.00
IUUC-Ago-007717	Ashbya gossypii	28.21	6.00e-43	169.00
IUUC-Acl-008188	Aspergillus clavatus	35.59	2.00e-62	233.00
IUUC-Afl-008456	Aspergillus flavus	36.27	9.00e-48	183.00
IUUC-Afu-009067	Aspergillus fumigatus	36.32	3.00e-64	239.00
IUUC-Ani-009483	Aspergillus nidulans	35.22	1.00e-61	230.00
IUUC-Ang-009639	Aspergillus niger	35.03	2.00e-61	230.00
IUUC-Aor-010040	Aspergillus oryzae	34.32	5.00e-61	229.00
IUUC-Ate-010310	Aspergillus terreus	30.81	4.00e-61	229.00
IUUC-Ame-011012	Astyanax mexicanus	75.49	3.00e-170	592.00
IUUC-Bgr-012311	Blumeria graminis	35.51	6.00e-47	182.00
IUUC-Bta-013299	Bos taurus	76.76	0.00e+00	1113.00
IUUC-Bci-013783	Botrytis cinerea	36.01	2.00e-59	223.00
IUUC-Bdi-015039	Brachypodium distachyon	31.09	5.00e-51	195.00
IUUC-Bol-015806	Brassica oleracea	36.48	2.00e-63	236.00
IUUC-Bra-017076	Brassica rapa	36.48	7.00e-64	238.00
IUUC-Cja-018715	Callithrix jacchus	76.29	0.00e+00	1156.00
IUUC-Cfa-020194	Canis familiaris	78.92	0.00e+00	1175.00
IUUC-Cpo-022272	Cavia porcellus	65.71	0.00e+00	934.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	34.67	7.00e-34	138.00
IUUC-Csa-023310	Chlorocebus sabaeus	78.87	0.00e+00	1173.00
IUUC-Cho-024966	Choloepus hoffmanni	74.31	0.00e+00	795.00
IUUC-Cin-025616	Ciona intestinalis	49.04	6.00e-109	387.00
IUUC-Csv-026043	Ciona savignyi	47.41	2.00e-99	355.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	33.77	4.00e-45	176.00
IUUC-Cne-026962	Cryptococcus neoformans	34.64	5.00e-48	186.00
IUUC-Cme-027113	Cyanidioschyzon merolae	30.61	7.00e-36	145.00
IUUC-Dre-028072	Danio rerio	80.09	0.00e+00	741.00
IUUC-Dno-029489	Dasypus novemcinctus	78.17	0.00e+00	1211.00
IUUC-Dor-031068	Dipodomys ordii	68.90	6.00e-133	468.00
IUUC-Dse-031553	Dothistroma septosporum	36.55	4.00e-58	219.00
IUUC-Dme-031759	Drosophila melanogaster	41.80	4.00e-84	306.00
IUUC-Ete-032549	Echinops telfairi	68.02	0.00e+00	770.00
IUUC-Eca-033380	Equus caballus	77.61	0.00e+00	1184.00
IUUC-Eeu-034818	Erinaceus europaeus	75.54	0.00e+00	1125.00
IUUC-Fca-035535	Felis catus	76.99	0.00e+00	1040.00
IUUC-Fal-036627	Ficedula albicollis	87.58	0.00e+00	1315.00
IUUC-Fox-037904	Fusarium oxysporum	36.81	6.00e-54	205.00
IUUC-Fso-038170	Fusarium solani	34.02	8.00e-53	201.00
IUUC-Gmo-039499	Gadus morhua	70.68	0.00e+00	681.00
IUUC-Ggr-040042	Gaeumannomyces graminis	35.12	2.00e-60	227.00
IUUC-Gga-040571	Gallus gallus	95.94	0.00e+00	1400.00
IUUC-Gac-041345	Gasterosteus aculeatus	78.71	0.00e+00	696.00
IUUC-Gma-044407	Glycine max	34.44	2.00e-58	219.00
IUUC-Ggo-044652	Gorilla gorilla	77.61	0.00e+00	1185.00
IUUC-Hsa-045864	Homo sapiens	77.48	0.00e+00	1182.00
IUUC-Hvu-047071	Hordeum vulgare	33.93	1.00e-53	203.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	82.76	0.00e+00	928.00
IUUC-Kpa-049132	Komagataella pastoris	30.87	4.00e-45	175.00
IUUC-Lch-050040	Latimeria chalumnae	76.20	0.00e+00	1023.00
IUUC-Lpe-050772	Leersia perrieri	28.64	2.00e-16	80.10
IUUC-Loc-052449	Lepisosteus oculatus	77.09	0.00e+00	750.00
IUUC-Lma-053248	Leptosphaeria maculans	35.95	2.00e-57	216.00
IUUC-Laf-054121	Loxodonta africana	77.42	0.00e+00	1181.00
IUUC-Mcc-055514	Macaca mulatta	78.42	0.00e+00	1168.00
IUUC-Meu-056873	Macropus eugenii	75.67	0.00e+00	865.00
IUUC-Mor-057243	Magnaporthe oryzae	33.51	3.00e-57	216.00
IUUC-Mpo-057439	Magnaporthe poae	35.39	1.00e-60	228.00
IUUC-Mtr-058457	Medicago truncatula	33.16	2.00e-56	213.00
IUUC-Mla-058929	Melampsora laricipopulina	30.51	4.00e-55	209.00
IUUC-Mga-060157	Meleagris gallopavo	94.05	0.00e+00	1424.00
IUUC-Mvi-060442	Microbotryum violaceum	33.27	1.00e-54	208.00
IUUC-Mmr-061062	Microcebus murinus	76.60	0.00e+00	1179.00
IUUC-Mdo-062798	Monodelphis domestica	83.17	0.00e+00	1257.00
IUUC-Mmu-064050	Mus musculus	72.80	0.00e+00	1107.00
IUUC-Mac-065202	Musa acuminata	33.57	2.00e-52	199.00
IUUC-Mpu-066554	Mustela putorius furo	76.00	0.00e+00	1128.00
IUUC-Mlu-068003	Myotis lucifugus	77.64	0.00e+00	1172.00
IUUC-Nfi-068612	Neosartorya fischeri	35.53	1.00e-62	234.00
IUUC-Ncr-068878	Neurospora crassa	33.84	3.00e-49	190.00
IUUC-Nle-069661	Nomascus leucogenys	77.36	0.00e+00	1170.00
IUUC-Opr-070944	Ochotona princeps	74.94	3.00e-164	571.00
IUUC-Ont-071266	Oreochromis niloticus	61.51	0.00e+00	854.00
IUUC-Oan-073442	Ornithorhynchus anatinus	84.88	0.00e+00	1206.00
IUUC-Ocu-073788	Oryctolagus cuniculus	73.56	0.00e+00	1014.00
IUUC-Oba-075085	Oryza barthii	33.93	2.00e-36	145.00
IUUC-Obr-076663	Oryza brachyantha	29.81	4.00e-46	179.00
IUUC-Ogl-076937	Oryza glaberrima	30.23	9.00e-50	191.00
IUUC-Ogu-078909	Oryza glumaepatula	30.48	4.00e-47	182.00
IUUC-Oin-079617	Oryza indica	31.37	7.00e-49	188.00
IUUC-Olo-081043	Oryza longistaminata	26.17	4.00e-24	105.00
IUUC-Ome-081646	Oryza meridionalis	24.61	1.00e-23	104.00
IUUC-Oni-082914	Oryza nivara	30.48	3.00e-47	182.00
IUUC-Oru-084878	Oryza rufipogon	30.48	3.00e-47	182.00
IUUC-Osa-085822	Oryza sativa	30.95	4.00e-51	195.00
IUUC-Ola-086931	Oryzias latipes	58.90	0.00e+00	825.00
IUUC-Oga-088443	Otolemur garnettii	76.03	0.00e+00	1174.00
IUUC-Oar-089325	Ovis aries	74.62	0.00e+00	1040.00
IUUC-Ptr-091584	Pan troglodytes	74.97	0.00e+00	1102.00
IUUC-Pan-092551	Papio anubis	76.86	0.00e+00	1132.00
IUUC-Psi-093366	Pelodiscus sinensis	89.31	0.00e+00	848.00
IUUC-Pno-095136	Phaeosphaeria nodorum	34.75	5.00e-49	189.00
IUUC-Ppa-095574	Physcomitrella patens	38.52	7.00e-61	228.00
IUUC-Pfo-097462	Poecilia formosa	58.48	0.00e+00	838.00
IUUC-Pab-098547	Pongo abelii	77.36	0.00e+00	1169.00
IUUC-Pop-099529	Populus trichocarpa	38.01	1.00e-63	236.00
IUUC-Pca-101066	Procavia capensis	69.90	0.00e+00	1035.00
IUUC-Ppe-102110	Prunus persica	35.87	2.00e-60	225.00
IUUC-Pva-103015	Pteropus vampyrus	73.74	0.00e+00	1095.00
IUUC-Ptt-103998	Puccinia triticina	32.84	1.00e-52	200.00
IUUC-Pte-104417	Pyrenophora teres	33.33	1.00e-55	211.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	34.42	2.00e-54	207.00
IUUC-Rno-105533	Rattus norvegicus	74.09	0.00e+00	1118.00
IUUC-Sce-106160	Saccharomyces cerevisiae	26.60	4.00e-39	156.00
IUUC-Sha-106590	Sarcophilus harrisii	82.98	0.00e+00	1232.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	35.68	3.00e-56	212.00
IUUC-Spo-108353	Schizosaccharomyces pombe	37.10	9.00e-62	230.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	36.39	8.00e-60	225.00
IUUC-Smo-108842	Selaginella moellendorffii	35.94	4.00e-37	147.00
IUUC-Sit-110781	Setaria italica	32.63	2.00e-55	210.00
IUUC-Sly-111797	Solanum lycopersicum	34.61	8.00e-56	211.00
IUUC-Stu-112188	Solanum tuberosum	34.26	6.00e-57	214.00
IUUC-Sbi-114862	Sorghum bicolor	33.05	3.00e-44	172.00
IUUC-Sre-115162	Sporisorium reilianum	34.16	5.00e-62	232.00
IUUC-Ssc-115505	Sus scrofa	89.39	9.00e-158	548.00
IUUC-Tgu-116535	Taeniopygia guttata	89.59	0.00e+00	1353.00
IUUC-Tru-117542	Takifugu rubripes	60.05	0.00e+00	863.00
IUUC-Tni-120200	Tetraodon nigroviridis	59.44	0.00e+00	854.00
IUUC-Tca-121548	Theobroma cacao	33.43	3.00e-45	176.00
IUUC-Tre-122124	Trichoderma reesei	35.71	6.00e-60	225.00
IUUC-Tvi-122457	Trichoderma virens	34.11	4.00e-53	202.00
IUUC-Tae-125646	Triticum aestivum	34.85	4.00e-57	215.00
IUUC-Tme-127180	Tuber melanosporum	38.34	6.00e-69	254.00
IUUC-Tbe-127530	Tupaia belangeri	65.77	0.00e+00	910.00
IUUC-Ttr-128549	Tursiops truncatus	71.09	0.00e+00	1048.00
IUUC-Uma-129381	Ustilago maydis	33.55	4.00e-63	236.00
IUUC-Vda-129889	Verticillium dahliae	33.16	1.00e-52	201.00
IUUC-Vpa-130100	Vicugna pacos	71.61	0.00e+00	1047.00
IUUC-Vvi-131366	Vitis vinifera	35.70	3.00e-63	236.00
IUUC-Xtr-132048	Xenopus tropicalis	68.97	0.00e+00	1019.00
IUUC-Xma-133593	Xiphophorus maculatus	79.23	0.00e+00	718.00
IUUC-Yli-134338	Yarrowia lipolytica	29.10	3.00e-33	136.00
IUUC-Zma-135586	Zea mays	30.25	3.00e-50	192.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence