iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036627

Ensembl Protein ID

ENSFALP00000006978.1

UniProt Accession

U3JW24; U3JW24_FICAL

Genbank Protein ID

ENSFALP00000006978

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01010683

Gene Name

USP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000006689.1	ENSFALT00000007007.1	ENSFALP00000006978.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.40e-68	228.5	396	775

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l+++  +   ++++++ +++++l+s+ +l++e++      k k+              a++p+
   Q: 396  GLINKGNWCYINATLQALVACPPMYHLMKS-IPMY-SKSQRPCTSTPMLDSFVRLMNEFTnmpvppKAKQAlgdkivrdirpgaAFEPT 482
           9*****************************.3333.33455799***************7777664333337888888999999***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk...................eknkpkeeeeeedkselsde.......aeek 133
            +++ l  +++++s + +q+Da+E+l f+l++l+ee+                      ++ p+eee+ee+ + ++de       +   
   Q: 483  YIYRLLTVIKSSLSeKGRQEDAEEYLGFILNGLHEEMLTlkkllsphnekvsvsngpeAQSVPREEEQEEQGEGSEDEweqvgprN--- 568
           *9999999999966599********************4455688888888888888855555555555555555555466666652... PP
   S: 134  kkkknk...........slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekc 211
                k           ++i+d+F+g+++ +++ ++  ++s + + f++l+l++++++ +   ++qd+Les +++e+++g    y++k 
   Q: 569  -----KssvtrqadfvqTPITDIFGGHIR-SVVYQQSSKESATLQLFFTLQLDIQSDKIR---TVQDALESLVARESVQG----YTTKT 644
           .....333444444666***********9.688999999*******************99...****************8....99999 PP
   S: 212  kkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...kkkYeLiavvvHsG.slssGHYv 296
           k+++e +++l+l+klP+vL+lhLkRf ++++++++ k+ k++e+   L++s+ + sp  k+k    +++Y+L+avv+H+G s+ +GHY+
   Q: 645  KQEVEISRRLTLEKLPPVLVLHLKRFVYEKTGGCQ-KLIKNIEYTVDLEISKELLSPGVKSKIskgQRTYRLFAVVYHHGnSATGGHYT 732
           ****************************9998886.***************9888877666546669********************** PP
   S: 297  ayvknekgk.WllfdDskVtevkeeevleetg.staYvlfYkr 337
           ++v +   + Wl++dD+ V++v+ ++v++    +taY+l+Y++
   Q: 733  TDVFQIGLNgWLRIDDQAVRVVHHSQVVKAALeRTAYLLYYRQ 775
           *****87777*****************996658********97 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

TGHRYIFGEF SPDEFNQFFV TPRCSVELPP YNETVSCGIK STGEEYQRIE FGVNEVIETQ 60
SSVLNNTDYS ISSTLNPQAP EFILSCAPAQ KTPDDALGDT NYNSIDCQFS DPTLALDSGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTTTTTTTC CTTTTGTGAG GAGTGGGTTT AGAAGGCAGA CCAGCCTTTG CCTGGGGCTT 60
GTATGAGCTG ATGCAGCTCC TCACCCCACA GGATAGCTTT AAACTGGTCA CAGGGTGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF07145--PAM2
PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071347--P:cellular response to interleukin-1
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	31.96	8.00e-47	181.00
IUUC-Aml-001584	Ailuropoda melanoleuca	76.07	0.00e+00	1098.00
IUUC-Atr-002927	Amborella trichopoda	34.96	2.00e-57	216.00
IUUC-Apl-003988	Anas platyrhynchos	88.47	0.00e+00	1327.00
IUUC-Aca-004461	Anolis carolinensis	93.11	6.00e-165	572.00
IUUC-Aly-006038	Arabidopsis lyrata	35.29	4.00e-54	205.00
IUUC-Ath-007328	Arabidopsis thaliana	35.04	2.00e-53	203.00
IUUC-Ago-007717	Ashbya gossypii	27.24	6.00e-43	169.00
IUUC-Acl-008188	Aspergillus clavatus	35.11	2.00e-61	230.00
IUUC-Afl-008456	Aspergillus flavus	37.05	2.00e-47	182.00
IUUC-Afu-009067	Aspergillus fumigatus	36.67	5.00e-64	239.00
IUUC-Ani-009483	Aspergillus nidulans	34.47	1.00e-60	228.00
IUUC-Ang-009639	Aspergillus niger	35.90	2.00e-61	230.00
IUUC-Aor-010040	Aspergillus oryzae	34.25	3.00e-60	226.00
IUUC-Ate-010310	Aspergillus terreus	34.61	2.00e-60	226.00
IUUC-Ame-011012	Astyanax mexicanus	74.20	9.00e-168	583.00
IUUC-Bgr-012311	Blumeria graminis	35.08	2.00e-45	177.00
IUUC-Bta-013299	Bos taurus	77.11	0.00e+00	1082.00
IUUC-Bci-013783	Botrytis cinerea	35.71	7.00e-58	218.00
IUUC-Bdi-015039	Brachypodium distachyon	31.35	1.00e-50	194.00
IUUC-Bol-015806	Brassica oleracea	36.20	2.00e-62	233.00
IUUC-Bra-017076	Brassica rapa	35.84	3.00e-63	236.00
IUUC-Cja-018715	Callithrix jacchus	76.32	0.00e+00	1128.00
IUUC-Cfa-020194	Canis familiaris	76.57	0.00e+00	1122.00
IUUC-Cpo-022272	Cavia porcellus	66.84	0.00e+00	900.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	34.00	9.00e-34	138.00
IUUC-Csa-023310	Chlorocebus sabaeus	76.83	0.00e+00	1135.00
IUUC-Cho-024966	Choloepus hoffmanni	72.48	0.00e+00	761.00
IUUC-Cin-025616	Ciona intestinalis	49.16	9.00e-110	390.00
IUUC-Csv-026043	Ciona savignyi	47.36	3.00e-100	358.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	33.08	2.00e-46	181.00
IUUC-Cne-026962	Cryptococcus neoformans	35.57	9.00e-51	195.00
IUUC-Cme-027113	Cyanidioschyzon merolae	31.38	2.00e-34	140.00
IUUC-Dre-028072	Danio rerio	77.68	0.00e+00	721.00
IUUC-Dno-029489	Dasypus novemcinctus	76.95	0.00e+00	1153.00
IUUC-Dor-031068	Dipodomys ordii	68.82	2.00e-131	462.00
IUUC-Dse-031553	Dothistroma septosporum	36.13	5.00e-57	216.00
IUUC-Dme-031759	Drosophila melanogaster	41.44	5.00e-83	303.00
IUUC-Ete-032549	Echinops telfairi	68.23	0.00e+00	738.00
IUUC-Eca-033380	Equus caballus	76.47	0.00e+00	1134.00
IUUC-Eeu-034818	Erinaceus europaeus	75.06	0.00e+00	1087.00
IUUC-Fca-035535	Felis catus	75.07	0.00e+00	998.00
IUUC-Fox-037904	Fusarium oxysporum	35.64	1.00e-52	201.00
IUUC-Fso-038170	Fusarium solani	32.95	1.00e-51	198.00
IUUC-Gmo-039499	Gadus morhua	69.30	0.00e+00	662.00
IUUC-Ggr-040042	Gaeumannomyces graminis	33.84	4.00e-60	226.00
IUUC-Gga-040571	Gallus gallus	89.04	0.00e+00	1318.00
IUUC-Gac-041345	Gasterosteus aculeatus	75.86	0.00e+00	677.00
IUUC-Gma-044407	Glycine max	34.78	1.00e-57	217.00
IUUC-Ggo-044652	Gorilla gorilla	76.57	0.00e+00	1139.00
IUUC-Hsa-045864	Homo sapiens	76.45	0.00e+00	1137.00
IUUC-Hvu-047071	Hordeum vulgare	33.25	2.00e-54	206.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	80.68	0.00e+00	895.00
IUUC-Kpa-049132	Komagataella pastoris	30.49	3.00e-45	176.00
IUUC-Lch-050040	Latimeria chalumnae	72.21	0.00e+00	971.00
IUUC-Lpe-050772	Leersia perrieri	30.73	4.00e-17	82.40
IUUC-Loc-052449	Lepisosteus oculatus	75.10	0.00e+00	727.00
IUUC-Lma-053248	Leptosphaeria maculans	34.77	6.00e-56	212.00
IUUC-Laf-054121	Loxodonta africana	76.32	0.00e+00	1121.00
IUUC-Mcc-055514	Macaca mulatta	76.83	0.00e+00	1134.00
IUUC-Meu-056873	Macropus eugenii	71.11	0.00e+00	800.00
IUUC-Mor-057243	Magnaporthe oryzae	32.35	2.00e-57	217.00
IUUC-Mpo-057439	Magnaporthe poae	33.84	4.00e-60	226.00
IUUC-Mtr-058457	Medicago truncatula	33.76	1.00e-55	210.00
IUUC-Mla-058929	Melampsora laricipopulina	30.91	1.00e-54	207.00
IUUC-Mga-060157	Meleagris gallopavo	86.94	0.00e+00	1313.00
IUUC-Mvi-060442	Microbotryum violaceum	32.82	2.00e-54	207.00
IUUC-Mmr-061062	Microcebus murinus	75.91	0.00e+00	1141.00
IUUC-Mdo-062798	Monodelphis domestica	78.56	0.00e+00	1157.00
IUUC-Mmu-064050	Mus musculus	73.01	0.00e+00	1100.00
IUUC-Mac-065202	Musa acuminata	33.89	9.00e-52	197.00
IUUC-Mpu-066554	Mustela putorius furo	75.72	0.00e+00	1087.00
IUUC-Mlu-068003	Myotis lucifugus	76.47	0.00e+00	1128.00
IUUC-Nfi-068612	Neosartorya fischeri	35.86	2.00e-61	231.00
IUUC-Ncr-068878	Neurospora crassa	34.35	3.00e-50	193.00
IUUC-Nle-069661	Nomascus leucogenys	76.32	0.00e+00	1127.00
IUUC-Opr-070944	Ochotona princeps	76.81	4.00e-163	567.00
IUUC-Ont-071266	Oreochromis niloticus	58.83	0.00e+00	827.00
IUUC-Oan-073442	Ornithorhynchus anatinus	78.77	0.00e+00	1124.00
IUUC-Ocu-073788	Oryctolagus cuniculus	72.49	0.00e+00	984.00
IUUC-Oba-075085	Oryza barthii	34.41	2.00e-35	142.00
IUUC-Obr-076663	Oryza brachyantha	30.52	2.00e-45	176.00
IUUC-Ogl-076937	Oryza glaberrima	30.16	3.00e-48	186.00
IUUC-Ogu-078909	Oryza glumaepatula	30.95	2.00e-46	180.00
IUUC-Oin-079617	Oryza indica	30.96	5.00e-47	182.00
IUUC-Olo-081043	Oryza longistaminata	26.49	5.00e-24	105.00
IUUC-Ome-081646	Oryza meridionalis	25.97	3.00e-23	103.00
IUUC-Oni-082914	Oryza nivara	30.95	1.00e-46	181.00
IUUC-Oru-084878	Oryza rufipogon	30.95	1.00e-46	181.00
IUUC-Osa-085822	Oryza sativa	30.95	2.00e-50	193.00
IUUC-Ola-086931	Oryzias latipes	57.59	0.00e+00	793.00
IUUC-Oga-088443	Otolemur garnettii	75.31	0.00e+00	1128.00
IUUC-Oar-089325	Ovis aries	74.56	0.00e+00	1011.00
IUUC-Ptr-091584	Pan troglodytes	74.06	0.00e+00	1060.00
IUUC-Pan-092551	Papio anubis	74.50	0.00e+00	1092.00
IUUC-Psi-093366	Pelodiscus sinensis	82.41	0.00e+00	798.00
IUUC-Pno-095136	Phaeosphaeria nodorum	33.51	2.00e-48	187.00
IUUC-Ppa-095574	Physcomitrella patens	38.36	2.00e-61	229.00
IUUC-Pfo-097462	Poecilia formosa	56.88	0.00e+00	816.00
IUUC-Pab-098547	Pongo abelii	76.32	0.00e+00	1126.00
IUUC-Pop-099529	Populus trichocarpa	38.27	4.00e-62	232.00
IUUC-Pca-101066	Procavia capensis	69.04	0.00e+00	980.00
IUUC-Ppe-102110	Prunus persica	36.62	1.00e-59	223.00
IUUC-Pva-103015	Pteropus vampyrus	72.27	0.00e+00	1046.00
IUUC-Ptt-103998	Puccinia triticina	32.75	1.00e-53	204.00
IUUC-Pte-104417	Pyrenophora teres	33.17	2.00e-54	207.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	34.16	9.00e-53	201.00
IUUC-Rno-105533	Rattus norvegicus	72.67	0.00e+00	1083.00
IUUC-Sce-106160	Saccharomyces cerevisiae	27.18	3.00e-40	160.00
IUUC-Sha-106590	Sarcophilus harrisii	77.30	0.00e+00	1146.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	35.28	4.00e-55	208.00
IUUC-Spo-108353	Schizosaccharomyces pombe	35.98	3.00e-60	225.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	34.95	2.00e-57	216.00
IUUC-Smo-108842	Selaginella moellendorffii	35.71	2.00e-37	148.00
IUUC-Sit-110781	Setaria italica	33.18	2.00e-55	210.00
IUUC-Sly-111797	Solanum lycopersicum	35.46	1.00e-55	210.00
IUUC-Stu-112188	Solanum tuberosum	34.61	8.00e-56	211.00
IUUC-Sbi-114862	Sorghum bicolor	33.14	1.00e-42	167.00
IUUC-Sre-115162	Sporisorium reilianum	33.33	5.00e-63	236.00
IUUC-Ssc-115505	Sus scrofa	85.81	9.00e-150	522.00
IUUC-Tgu-116535	Taeniopygia guttata	96.32	0.00e+00	1420.00
IUUC-Tru-117542	Takifugu rubripes	58.70	0.00e+00	838.00
IUUC-Tni-120200	Tetraodon nigroviridis	58.36	0.00e+00	830.00
IUUC-Tca-121548	Theobroma cacao	33.04	3.00e-43	169.00
IUUC-Tre-122124	Trichoderma reesei	34.75	1.00e-61	230.00
IUUC-Tvi-122457	Trichoderma virens	33.76	5.00e-54	206.00
IUUC-Tae-125646	Triticum aestivum	34.43	6.00e-56	212.00
IUUC-Tme-127180	Tuber melanosporum	38.98	2.00e-68	253.00
IUUC-Tbe-127530	Tupaia belangeri	65.55	0.00e+00	874.00
IUUC-Ttr-128549	Tursiops truncatus	69.09	0.00e+00	994.00
IUUC-Uma-129381	Ustilago maydis	32.18	2.00e-62	234.00
IUUC-Vda-129889	Verticillium dahliae	33.77	7.00e-53	202.00
IUUC-Vpa-130100	Vicugna pacos	71.07	0.00e+00	993.00
IUUC-Vvi-131366	Vitis vinifera	36.71	5.00e-63	235.00
IUUC-Xtr-132048	Xenopus tropicalis	64.29	0.00e+00	931.00
IUUC-Xma-133593	Xiphophorus maculatus	57.39	0.00e+00	816.00
IUUC-Yli-134338	Yarrowia lipolytica	28.25	1.00e-32	134.00
IUUC-Zma-135255	Zea mays	31.51	2.00e-55	211.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence