iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-006589

UUCD1 version

UUC-ArT-01645

Ensembl Protein ID

AT4G36410.1

UniProt Accession

O23239; UBC17_ARATH

Genbank Protein ID

AAC39326.1; AAY44857.1; CAB16814.1; CAB80307.1; AEE86653.1; AAM65622.1

Protein Name

Probable ubiquitin-conjugating enzyme E2 17; E2 ubiquitin-conjugating enzyme 17; Ubiquitin carrier protein 17

Genbank Nucleotide ID

AF028340; DQ027031; Z99708; AL161589; CP002687; AY088076

Gene Name

UBC17; At4g36410; AP22.89; C7A10.950

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT4G36410	AT4G36410.1	AT4G36410.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT	Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.70e-33	115.1	19	141

Active Site

Position(s)	Description	Evidence
99	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk.ifhPnvyenGkvClsilkeeekWspals 97
           Rl+ke++e++++pp+g++ +++d+  l++w +++ G ++t Y++++++l++efpe+YP+++P+v f  +  +hP++y+nG++Cl++l   + Wspa+ 
   Q: 19   RLQKEFMEWQTNPPSGFKHRVSDN--LQRWIIEVHGVPGTLYANETYQLQVEFPEHYPMEAPQVIFQHPaPLHPHIYSNGHICLDVLY--DSWSPAMR 112
           9****************9998877..*****************************************9989****************9..******** PP
   S: 98   vesvllsiqsll.aepnpesplneeaa.e 124
           ++s++lsi s+l ++   ++p +++ + +
   Q: 113  LSSICLSILSMLsSSSVKQKPKDNDHYlK 141
           ************54466778887776634 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.

Protein Sequence
(Fasta)

MTSSSESTRK GLTKIATNRL QKEFMEWQTN PPSGFKHRVS DNLQRWIIEV HGVPGTLYAN 60
ETYQLQVEFP EHYPMEAPQV IFQHPAPLHP HIYSNGHICL DVLYDSWSPA MRLSSICLSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAACACACA CAATCTCTCT CTCTCACACT CACTGTAATA AACACAAATG ACGAGTTCTT 60
CTGAATCAAC TCGCAAGGTT GGTTAATTGT TTCTTTAACT AAATATAACA GTACCTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0009739--P:response to gibberellin

KEGG

ath:AT4G36410

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006414	Arabidopsis lyrata	97.52	9.00e-83	298.00
IUUC-Bol-015300	Brassica oleracea	95.65	5.00e-81	292.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence