iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007153

UUCD1 version

UUC-ArT-01519

Ensembl Protein ID

AT1G20780.1

UniProt Accession

Q9LM76; Q93YT4; PUB44_ARATH

Genbank Protein ID

AAF80621.1; AEE30021.1; ANM60921.1; ANM60922.1; AAL24123.1; AAM20387.1

Protein Name

U-box domain-containing protein 44; Plant U-box protein 44; Protein SENESCENCE-ASSOCIATED E3 UBIQUITIN LIGASE 1; RING-type E3 ubiquitin transferase PUB44

Genbank Nucleotide ID

AC069251; CP002684; CP002684; CP002684; AY059775; AY096753

Gene Name

PUB44; SAUL1; At1g20780; F2D10.27

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT1G20780	AT1G20780.1	AT1G20780.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	Mentha
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/U-box	U-box	19309463; 14657406

Classification

Family	E-value	Score	Start	End
E3 activity/RING/U-box	1.90e-26	92.8	23	100

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk.....tcPvtrqplteedlvPnltlrrliqawceenss 74
           ++e+f+Cp+++e+M+dPv+l++G t++r++Iekw+++++      +cP+t+q+lt++d+  +++lr++i++w+++n+ 
   Q: 23   IYEAFICPLTKEVMHDPVTLENGRTFEREAIEKWFKECRDsgrppSCPLTSQELTSTDVSASIALRNTIEEWRSRNDA 100
           89*********************************888777788******************************9975 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Functions as an E3 ubiquitin-protein ligase. Prevents premature senescence probably by targeting proteins involved in this process for degradation. Promotes the degradation of AAO3 and thus represses abscisic acid (ABA) biosynthesis.

Protein Sequence
(Fasta)

MVGSSDGDQS DDSSHFERGV DHIYEAFICP LTKEVMHDPV TLENGRTFER EAIEKWFKEC 60
RDSGRPPSCP LTSQELTSTD VSASIALRNT IEEWRSRNDA AKLDIARQSL FLGNAETDIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCACGTCT CTCTCTATCT CTCTCTCTCA CATGACTTTT CGATTTTAGT CAACCTTTCG 60
TGCTTTTCTC TTAAAAATTC GATTTTTTCT TCAACCCATC TTCTTCTCTG TTATTTCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000225--Armadillo
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50176--ARM_REPEAT
PS51698--U_BOX

Pfam

PF00514--Arm
PF04564--U-box

SMART

SM00185--ARM
SM00504--Ubox

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0070696--F:transmembrane receptor protein serine/threonine kinase binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0010150--P:leaf senescence
GO:0090359--P:negative regulation of abscisic acid biosynthetic process
GO:0010115--P:regulation of abscisic acid biosynthetic process
GO:0010380--P:regulation of chlorophyll biosynthetic process
GO:0010271--P:regulation of chlorophyll catabolic process

KEGG

ath:AT1G20780

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006004	Arabidopsis lyrata	96.69	0.00e+00	1466.00
IUUC-Bol-016384	Brassica oleracea	86.66	0.00e+00	1266.00
IUUC-Bra-017058	Brassica rapa	87.04	0.00e+00	1295.00
IUUC-Gma-043617	Glycine max	66.79	0.00e+00	1009.00
IUUC-Oba-075225	Oryza barthii	59.19	0.00e+00	857.00
IUUC-Ogl-077529	Oryza glaberrima	59.19	0.00e+00	856.00
IUUC-Ogu-078735	Oryza glumaepatula	58.94	0.00e+00	853.00
IUUC-Oin-079422	Oryza indica	59.19	0.00e+00	848.00
IUUC-Olo-080644	Oryza longistaminata	55.50	0.00e+00	776.00
IUUC-Ome-081455	Oryza meridionalis	59.24	0.00e+00	852.00
IUUC-Oni-082690	Oryza nivara	59.19	0.00e+00	848.00
IUUC-Opu-083157	Oryza punctata	59.06	0.00e+00	851.00
IUUC-Oru-085058	Oryza rufipogon	59.19	0.00e+00	848.00
IUUC-Osa-086000	Oryza sativa	59.19	0.00e+00	848.00
IUUC-Sly-111702	Solanum lycopersicum	66.67	0.00e+00	932.00
IUUC-Sbi-113974	Sorghum bicolor	51.64	0.00e+00	744.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence