iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/BCR/BTB_3-box	BTB_3-box	15772280

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.70e-07	30.7	55	118
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	9.80e-10	37.6	159	189

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvg.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgk 64
           aDv+++ + +  + ah  v+  +S+v + +++++ ++s+ ++ + i +v + ++r++++FlY++ 
   Q: 55   ADVLIHTDdNGLIYAHSNVIGMASDVIRGMMKQHKRKSH-RKSISILGVPHHALRVFIRFLYSSC 118
           699****9999***************************9.**********************976 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
           eN+++++++A l+d+p+L + ++++il++F+
   Q: 159  ENVIDVFQLALLCDAPRLGLLCHRMILNNFE 189
           9*****************************5 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Interacts with CUL3A.

Protein Sequence
(Fasta)

MENMDDFSPE NVLAPPPPPP PMKKSTDLFM QRSNSFVSKA TRDSWDRMFD EAHGADVLIH 60
TDDNGLIYAH SNVIGMASDV IRGMMKQHKR KSHRKSISIL GVPHHALRVF IRFLYSSCYE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTTCTTTCT CTTATTTTCC TATTCTTGAA AACACACAAC ACATCTCATT TCTCCGCTGT 60
TTCGTCGGCA AATTTTCCCA TTTTTGATTC CGAAGATAAT AGATATTATC AACAGAGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR034089--SPOP_C
IPR000197--Znf_TAZ

PROSITE

PS50097--BTB
PS50134--ZF_TAZ

Pfam

PF00651--BTB
PF02135--zf-TAZ

SMART

SM00225--BTB
SM00551--ZnF_TAZ

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0005516--F:calmodulin binding
GO:0004402--F:histone acetyltransferase activity
GO:0003712--F:transcription cofactor activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030162--P:regulation of proteolysis
GO:0006355--P:regulation of transcription, DNA-templated
GO:0009733--P:response to auxin
GO:0010200--P:response to chitin
GO:0009409--P:response to cold
GO:0042542--P:response to hydrogen peroxide
GO:0009751--P:response to salicylic acid

KEGG

ath:AT4G37610

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006540	Arabidopsis lyrata	94.04	0.00e+00	705.00
IUUC-Bol-016122	Brassica oleracea	82.37	0.00e+00	653.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence