iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013405

Ensembl Protein ID

ENSBTAP00000053649.2

UniProt Accession

F1N787; F1N787_BOVIN

Genbank Protein ID

ENSBTAP00000053649

Protein Name

DNA repair protein REV1

Genbank Nucleotide ID

DAAA02030163

Gene Name

REV1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000043999.2	ENSBTAT00000061518.2	ENSBTAP00000053649.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBM	8.40e-20	69.9	962	990

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBM

   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
           ++sqvDpeVf++LP e+Q+E++a+++q++
   Q: 962  AFSQVDPEVFAALPVELQKELRAAYDQRQ 990
           59*************************98 PP

Organism

Bos taurus

Functional Description
(View)

Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.

Protein Sequence
(Fasta)

ACFIINFTDP SAEELRKLMM LHGGQYHVYY SRSKTTHIIA TNLPNAKIKE LKGEKVIRPE 60
WIVESIKAGR LLSCIPYQLY SKPSSVQKSL NFNPVCKPED PLPGPSSITK QLNDRVNHII 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGTGTTTTA TTATTAATTT TACAGATCCA TCTGCCGAGG AATTGAGAAA GCTAATGATG 60
TTGCATGGAG GCCAGTATCA CGTGTATTAT TCCAGATCCA AAACAACACA CATCATTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000375	Aegilops tauschii	30.77	5.00e-30	126.00
IUUC-Aml-001185	Ailuropoda melanoleuca	82.48	0.00e+00	1897.00
IUUC-Atr-002915	Amborella trichopoda	30.45	5.00e-99	356.00
IUUC-Apl-004054	Anas platyrhynchos	71.93	0.00e+00	1624.00
IUUC-Aca-004304	Anolis carolinensis	65.45	0.00e+00	1486.00
IUUC-Aly-005696	Arabidopsis lyrata	34.77	1.00e-83	305.00
IUUC-Ath-006893	Arabidopsis thaliana	33.74	5.00e-85	309.00
IUUC-Ago-007722	Ashbya gossypii	29.39	1.00e-41	165.00
IUUC-Acl-008347	Aspergillus clavatus	37.28	2.00e-85	310.00
IUUC-Afl-008444	Aspergillus flavus	36.27	9.00e-87	315.00
IUUC-Afu-008837	Aspergillus fumigatus	35.96	2.00e-82	301.00
IUUC-Ani-009188	Aspergillus nidulans	37.90	6.00e-90	325.00
IUUC-Ang-009866	Aspergillus niger	38.54	9.00e-94	338.00
IUUC-Aor-010107	Aspergillus oryzae	36.27	9.00e-87	315.00
IUUC-Ate-010359	Aspergillus terreus	36.36	4.00e-87	316.00
IUUC-Ame-010664	Astyanax mexicanus	48.19	0.00e+00	1001.00
IUUC-Bgr-012244	Blumeria graminis	34.47	2.00e-76	280.00
IUUC-Bci-013849	Botrytis cinerea	31.22	3.00e-87	317.00
IUUC-Bdi-014066	Brachypodium distachyon	35.86	1.00e-82	301.00
IUUC-Bol-015544	Brassica oleracea	35.50	8.00e-86	311.00
IUUC-Bra-017792	Brassica rapa	34.32	2.00e-82	301.00
IUUC-Cel-018148	Caenorhabditis elegans	33.33	4.00e-80	293.00
IUUC-Cja-019742	Callithrix jacchus	71.05	0.00e+00	1334.00
IUUC-Cfa-020112	Canis familiaris	82.64	0.00e+00	1910.00
IUUC-Cpo-022152	Cavia porcellus	77.82	0.00e+00	1867.00
IUUC-Cre-022951	Chlamydomonas reinhardtii	41.00	3.00e-37	150.00
IUUC-Csa-023504	Chlorocebus sabaeus	80.63	0.00e+00	1885.00
IUUC-Cho-024780	Choloepus hoffmanni	74.21	0.00e+00	630.00
IUUC-Cin-025276	Ciona intestinalis	40.28	1.00e-110	394.00
IUUC-Csv-026283	Ciona savignyi	43.24	3.00e-111	395.00
IUUC-Cgl-026726	Colletotrichum gloeosporioides	27.90	7.00e-87	315.00
IUUC-Cne-027079	Cryptococcus neoformans	34.52	4.00e-78	286.00
IUUC-Cme-027346	Cyanidioschyzon merolae	27.57	2.00e-44	174.00
IUUC-Dre-028073	Danio rerio	48.55	0.00e+00	984.00
IUUC-Dno-030038	Dasypus novemcinctus	78.90	0.00e+00	1831.00
IUUC-Dor-031100	Dipodomys ordii	78.05	0.00e+00	1418.00
IUUC-Dse-031310	Dothistroma septosporum	30.86	3.00e-82	300.00
IUUC-Dme-031991	Drosophila melanogaster	41.82	5.00e-112	399.00
IUUC-Ete-033082	Echinops telfairi	73.20	0.00e+00	1330.00
IUUC-Eca-033471	Equus caballus	82.89	0.00e+00	1922.00
IUUC-Eeu-034993	Erinaceus europaeus	78.34	0.00e+00	1217.00
IUUC-Fca-035367	Felis catus	82.55	0.00e+00	1942.00
IUUC-Fal-036973	Ficedula albicollis	70.35	0.00e+00	1536.00
IUUC-Fox-037677	Fusarium oxysporum	30.37	4.00e-85	309.00
IUUC-Fso-038252	Fusarium solani	28.94	3.00e-100	360.00
IUUC-Gmo-039669	Gadus morhua	61.02	5.00e-170	592.00
IUUC-Ggr-039988	Gaeumannomyces graminis	35.69	3.00e-84	306.00
IUUC-Gga-040423	Gallus gallus	71.93	0.00e+00	1607.00
IUUC-Gac-042134	Gasterosteus aculeatus	49.86	0.00e+00	793.00
IUUC-Gma-042929	Glycine max	35.32	3.00e-85	310.00
IUUC-Ggo-044528	Gorilla gorilla	81.31	0.00e+00	1887.00
IUUC-Hsa-046259	Homo sapiens	80.98	0.00e+00	1851.00
IUUC-Hvu-047139	Hordeum vulgare	36.24	2.00e-56	213.00
IUUC-Itr-048621	Ictidomys tridecemlineatus	80.40	0.00e+00	1895.00
IUUC-Kpa-049169	Komagataella pastoris	30.27	3.00e-64	240.00
IUUC-Lch-050471	Latimeria chalumnae	61.84	0.00e+00	1379.00
IUUC-Lpe-050800	Leersia perrieri	32.29	1.00e-83	304.00
IUUC-Loc-052320	Lepisosteus oculatus	46.86	0.00e+00	855.00
IUUC-Lma-053149	Leptosphaeria maculans	29.30	3.00e-86	313.00
IUUC-Laf-053810	Loxodonta africana	79.34	0.00e+00	1761.00
IUUC-Mcc-055574	Macaca mulatta	80.88	0.00e+00	1845.00
IUUC-Meu-055945	Macropus eugenii	61.69	0.00e+00	935.00
IUUC-Mor-057195	Magnaporthe oryzae	30.24	8.00e-90	325.00
IUUC-Mpo-057488	Magnaporthe poae	35.08	3.00e-84	306.00
IUUC-Mtr-057955	Medicago truncatula	34.99	6.00e-87	316.00
IUUC-Mla-059027	Melampsora laricipopulina	35.40	9.00e-77	281.00
IUUC-Mga-060156	Meleagris gallopavo	71.77	0.00e+00	1618.00
IUUC-Mvi-060398	Microbotryum violaceum	34.45	4.00e-81	296.00
IUUC-Mmr-061113	Microcebus murinus	81.56	0.00e+00	1878.00
IUUC-Mdo-063001	Monodelphis domestica	75.64	0.00e+00	1726.00
IUUC-Mmu-063180	Mus musculus	77.33	0.00e+00	1799.00
IUUC-Mac-065551	Musa acuminata	38.70	5.00e-52	199.00
IUUC-Mpu-066525	Mustela putorius furo	82.89	0.00e+00	1906.00
IUUC-Mlu-067877	Myotis lucifugus	80.65	0.00e+00	1833.00
IUUC-Nfi-068418	Neosartorya fischeri	31.57	9.00e-84	305.00
IUUC-Ncr-068648	Neurospora crassa	31.47	1.00e-84	308.00
IUUC-Nle-069959	Nomascus leucogenys	80.98	0.00e+00	1862.00
IUUC-Opr-070522	Ochotona princeps	78.31	0.00e+00	1033.00
IUUC-Ont-072293	Oreochromis niloticus	50.29	0.00e+00	805.00
IUUC-Oan-073519	Ornithorhynchus anatinus	73.46	0.00e+00	1700.00
IUUC-Ocu-074492	Oryctolagus cuniculus	78.38	0.00e+00	1706.00
IUUC-Oba-075567	Oryza barthii	35.07	4.00e-85	310.00
IUUC-Obr-076332	Oryza brachyantha	35.95	2.00e-83	304.00
IUUC-Ogl-077348	Oryza glaberrima	35.07	5.00e-85	309.00
IUUC-Ogu-078779	Oryza glumaepatula	32.09	8.00e-85	308.00
IUUC-Oin-079738	Oryza indica	31.74	5.00e-73	270.00
IUUC-Olo-080701	Oryza longistaminata	31.74	3.00e-73	270.00
IUUC-Ome-081708	Oryza meridionalis	31.79	4.00e-82	300.00
IUUC-Oni-082251	Oryza nivara	34.87	9.00e-83	301.00
IUUC-Opu-083528	Oryza punctata	34.66	8.00e-77	282.00
IUUC-Oru-084293	Oryza rufipogon	34.10	4.00e-80	293.00
IUUC-Osa-085549	Oryza sativa	35.07	5.00e-85	309.00
IUUC-Ola-086793	Oryzias latipes	49.85	0.00e+00	815.00
IUUC-Olu-087786	Ostreococcus lucimarinus	28.91	2.00e-64	239.00
IUUC-Oga-089006	Otolemur garnettii	81.22	0.00e+00	1866.00
IUUC-Oar-089597	Ovis aries	95.34	0.00e+00	2203.00
IUUC-Ptr-091520	Pan troglodytes	80.98	0.00e+00	1850.00
IUUC-Pan-092333	Papio anubis	81.05	0.00e+00	1837.00
IUUC-Psi-094004	Pelodiscus sinensis	72.86	0.00e+00	1665.00
IUUC-Pma-094128	Petromyzon marinus	52.10	6.00e-90	325.00
IUUC-Pno-094849	Phaeosphaeria nodorum	28.33	1.00e-79	291.00
IUUC-Ppa-095714	Physcomitrella patens	27.64	3.00e-92	333.00
IUUC-Pfo-096569	Poecilia formosa	47.00	0.00e+00	912.00
IUUC-Pab-097960	Pongo abelii	80.40	0.00e+00	1839.00
IUUC-Pop-098921	Populus trichocarpa	36.12	1.00e-81	298.00
IUUC-Pca-100509	Procavia capensis	66.48	0.00e+00	1058.00
IUUC-Ppe-101730	Prunus persica	33.90	2.00e-88	321.00
IUUC-Pva-102142	Pteropus vampyrus	79.65	0.00e+00	1809.00
IUUC-Pgr-103446	Puccinia graminis	31.05	4.00e-70	259.00
IUUC-Ptt-103849	Puccinia triticina	29.60	4.00e-71	263.00
IUUC-Pte-104128	Pyrenophora teres	30.63	4.00e-87	316.00
IUUC-Pyt-104754	Pyrenophora triticirepentis	31.90	4.00e-84	306.00
IUUC-Rno-104871	Rattus norvegicus	75.14	0.00e+00	1750.00
IUUC-Sce-106236	Saccharomyces cerevisiae	27.03	2.00e-41	164.00
IUUC-Sha-106962	Sarcophilus harrisii	74.96	0.00e+00	1704.00
IUUC-Sja-107691	Schizosaccharomyces japonicus	32.92	5.00e-62	233.00
IUUC-Spo-108170	Schizosaccharomyces pombe	34.30	5.00e-63	236.00
IUUC-Ssl-108668	Sclerotinia sclerotiorum	29.32	1.00e-87	318.00
IUUC-Smo-109554	Selaginella moellendorffii	35.40	8.00e-81	295.00
IUUC-Sit-110479	Setaria italica	35.57	3.00e-71	263.00
IUUC-Sly-111752	Solanum lycopersicum	36.61	9.00e-88	318.00
IUUC-Sar-113304	Sorex araneus	80.52	0.00e+00	1867.00
IUUC-Sbi-114196	Sorghum bicolor	36.09	3.00e-71	263.00
IUUC-Sre-115151	Sporisorium reilianum	32.64	4.00e-82	300.00
IUUC-Ssc-116104	Sus scrofa	84.33	0.00e+00	1938.00
IUUC-Tgu-117438	Taeniopygia guttata	71.36	0.00e+00	1599.00
IUUC-Tru-118553	Takifugu rubripes	46.75	0.00e+00	911.00
IUUC-Tsy-119056	Tarsius syrichta	79.73	0.00e+00	1717.00
IUUC-Tni-119933	Tetraodon nigroviridis	46.73	0.00e+00	869.00
IUUC-Tca-121376	Theobroma cacao	36.34	1.00e-83	304.00
IUUC-Tre-121972	Trichoderma reesei	34.13	9.00e-77	282.00
IUUC-Tvi-122342	Trichoderma virens	29.93	6.00e-78	286.00
IUUC-Tae-123898	Triticum aestivum	32.76	6.00e-86	312.00
IUUC-Tur-126735	Triticum urartu	35.75	6.00e-33	136.00
IUUC-Tme-126999	Tuber melanosporum	32.32	2.00e-78	287.00
IUUC-Tbe-127280	Tupaia belangeri	86.03	2.00e-136	480.00
IUUC-Ttr-129104	Tursiops truncatus	85.80	0.00e+00	1922.00
IUUC-Uma-129562	Ustilago maydis	31.88	2.00e-83	304.00
IUUC-Vda-129862	Verticillium dahliae	30.42	3.00e-86	313.00
IUUC-Vpa-130819	Vicugna pacos	82.67	0.00e+00	993.00
IUUC-Vvi-131111	Vitis vinifera	34.78	2.00e-82	300.00
IUUC-Xtr-132629	Xenopus tropicalis	58.55	0.00e+00	1250.00
IUUC-Xma-134065	Xiphophorus maculatus	45.02	0.00e+00	786.00
IUUC-Yli-134633	Yarrowia lipolytica	32.86	1.00e-63	238.00
IUUC-Zma-135176	Zea mays	33.13	2.00e-87	317.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence