iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-058360

Ensembl Protein ID

AES98351

UniProt Accession

G7K621; G7K621_MEDTR

Genbank Protein ID

AES98351.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

CM001221

Gene Name

MTR_5g067400

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_5g067400	AES98351	AES98351

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_Other	5.20e-18	66.1	241	313

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_Other

   S: 1    vqvtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekk 73
           +q+ v++l g++ +l+v++sdt+ ++K+ki +k+gip ++qrLi++Gk Led+ tLa+y+++++sti+l+++ 
   Q: 241  MQIYVEDLIGKTIPLRVESSDTIVDVKKKILDKEGIPIHEQRLINDGKQLEDNLTLASYNIQENSTILLVLRL 313
           678899999**9**********************************************************885 PP

Organism

Medicago truncatula

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MEPLMISNPN LFDCCKCFQP LTIPVFQCDN GHIVCSTCCT KLRNKCHECS LRISSKRCKA 60
IENILLSIEM PCPNANHGCK EKISYTGNRK HEDECIYFPC YCPLSGCDFA ASSEVLSNHF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGGAGTCTA CAATTTATCT GTGTTTTAAA AGTAATTTTT AGTAGCGACT TTATTTTGAT 60
TTTGATCATA TAAGAAAAGT TGTAATGGAG CCTCTAATGA TTTCCAACCC TAATTTGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR019956--Ubiquitin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50053--UBIQUITIN_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina
PF00240--ubiquitin

PRINTS

PR00348--UBIQUITIN

SMART

SM00213--UBQ

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mtr:MTR_5g067400

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005653	Arabidopsis lyrata	35.56	8.00e-38	149.00
IUUC-Ath-007187	Arabidopsis thaliana	34.82	2.00e-35	141.00
IUUC-Bol-016089	Brassica oleracea	34.73	7.00e-37	146.00
IUUC-Bra-016844	Brassica rapa	39.65	1.00e-40	159.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence