iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007573

UUCD1 version

UUC-ArT-01548

Ensembl Protein ID

AT1G15100.1

UniProt Accession

Q9ZT50; Q4TU39; RHA2A_ARATH

Genbank Protein ID

AAC68671.1; AAY57583.1; AAD39638.1; AEE29264.1; AAL91611.1; AAM16213.1; AAM65842.1

Protein Name

E3 ubiquitin-protein ligase RHA2A; RING-H2 finger A2a; RING-H2 zinc finger protein RHA2a; RING-type E3 ubiquitin transferase RHA2A

Genbank Nucleotide ID

AF078822; DQ059097; AC007591; CP002684; AY075590; AY094057; AY088303

Gene Name

RHA2A; At1g15100; F9L1.3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT1G15100	AT1G15100.1	AT1G15100.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
Mentha
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	16339806; 19286935

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	1.10e-08	36.4	86	128

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +Cl+ +k+g  ++ l C Hvfh++Cl+ w     + + +f+CPlCr
   Q: 86   CVVCLSKLKEGeeVRKLECRHVFHKKCLEGW-----LHQFNFTCPLCR 128
           ********55455******************.....68889******8 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

E3 ubiquitin-protein ligase involved in the positive regulation of abscisic acid (ABA) signaling and responses to salt and osmotic stresses during seed germination and early seedling development (PubMed:19286935, PubMed:21478367). Acts additively with RHA2B in regulating ABA signaling and drought response (PubMed:21478367). Possesses E3 ubiquitin ligase activity in vitro (PubMed:15644464, PubMed:19286935).

Protein Sequence
(Fasta)

MGLQGQLSDV SSDSIPLMLL SLLAVFINHL RSFLLRLTSK SNPNLPVDDV SIASGLANII 60
VLADQLSLNR LFSYRCGDGG GGGSDCVVCL SKLKEGEEVR KLECRHVFHK KCLEGWLHQF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGAAGAAG AAGAAGAAGA AGAAGAAGAA GAAGAAGAAG AAAGATGGGG CTACAAGGTC 60
AGCTAAGTGA CGTCTCTTCC GATTCAATCC CTCTTATGCT CCTCTCTCTC CTCGCCGTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0938--Abscisic acid signaling pathway
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0346--Stress response
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0009738--P:abscisic acid-activated signaling pathway
GO:0009789--P:positive regulation of abscisic acid-activated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0047484--P:regulation of response to osmotic stress
GO:0009651--P:response to salt stress

KEGG

ath:AT1G15100

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002667	Amborella trichopoda	37.71	1.00e-18	85.50
IUUC-Aly-005399	Arabidopsis lyrata	93.24	2.00e-68	249.00
IUUC-Acl-008182	Aspergillus clavatus	51.11	7.00e-10	55.80
IUUC-Afl-008599	Aspergillus flavus	55.56	1.00e-10	58.20
IUUC-Aor-010099	Aspergillus oryzae	36.73	3.00e-09	53.90
IUUC-Bdi-014774	Brachypodium distachyon	59.18	4.00e-14	70.10
IUUC-Bol-016030	Brassica oleracea	80.25	8.00e-61	224.00
IUUC-Bra-017622	Brassica rapa	82.30	2.00e-45	173.00
IUUC-Gma-043050	Glycine max	45.56	2.00e-35	140.00
IUUC-Lpe-051178	Leersia perrieri	62.50	6.00e-14	70.10
IUUC-Mtr-057686	Medicago truncatula	50.31	4.00e-38	149.00
IUUC-Mac-065273	Musa acuminata	45.87	1.00e-20	91.30
IUUC-Ppe-101263	Prunus persica	48.24	7.00e-27	112.00
IUUC-Sit-110184	Setaria italica	44.12	2.00e-12	64.70
IUUC-Sly-111821	Solanum lycopersicum	51.81	6.00e-38	149.00
IUUC-Stu-112683	Solanum tuberosum	50.00	4.00e-37	146.00
IUUC-Sbi-114160	Sorghum bicolor	36.17	7.00e-12	62.80
IUUC-Tca-121817	Theobroma cacao	54.27	2.00e-37	147.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence