iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GLYMA13G43680	GLYMA13G43680.3	GLYMA13G43680.3
GLYMA13G43680	GLYMA13G43680.1	GLYMA13G43680.1
GLYMA13G43680	GLYMA13G43680.2	GLYMA13G43680.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-35	121.4	184	224
UBD/Beta-Prp	3.50e-68	231.6	14	290

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+ +v+c+++    d ++l++GsdD+t kvWD+ t  ++++
   Q: 184  HQKGVNCVDYftgGDkPYLITGSDDHTAKVWDYQTKSCVQT 224
           999*****966*9778*******************999986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
           ++++++cv+ +p +++++++ ++gt+ +w+++++++ +s++  e +v++ kf+ ++++ v g++D++i+v++++t + v ++++h+d+++++++
   Q: 14   RSERVKCVDLHPTEPWILASLYSGTVCIWNYQSQTMAKSFEVTELPVRSAKFIARKQWVVAGADDMFIRVYNYNTMDKVKVFEAHTDYIRCVAV 107
           67789***************************************************************************************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsngk 193
           +p+  +++s s+d  i++wd+e+g+   ++++gh++ v+ v+++p++ n ++s+slDrt+++W+l + +   tl   h++ v++++     +++
   Q: 108  HPTLPYVLSSSDDMLIKLWDWEKGWICTQIFEGHSHYVMQVTFNPKDtNTFASASLDRTIKIWNLGSPDPNFTLDA-HQKGVNCVDyfTGGDKP 200
           *************************9999*********************************************98.*********6444555* PP
   S: 194  elvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlg 283
           +l++gs+d t k+wd+qt++cv+tl+ght nv+ v f+p+  ++++gs+Dg++riW +++  l +tl++  ++v+++ +l+ +++v++  
   Q: 201  YLITGSDDHTAKVWDYQTKSCVQTLEGHTHNVSAVCFHPELPIIITGSEDGTVRIWHSTTYRLENTLNYGLERVWAIGYLKSSRRVVIGY 290
           *******************************************************************************99998888544 PP

Organism

Glycine max

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLEIKRK LAQRSERVKC VDLHPTEPWI LASLYSGTVC IWNYQSQTMA KSFEVTELPV 60
RSAKFIARKQ WVVAGADDMF IRVYNYNTMD KVKVFEAHTD YIRCVAVHPT LPYVLSSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTACACAG AGCTCTCTTA CAAAAACAAA TAAACACATT TCTCTCTCTC TCTCTCTCTC 60
TGAGCTCGTC GAATTCGAAA TCTGATCTCC AACGATTGAT CTCGGTAGAG GCTAGTGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	73.93	0.00e+00	1397.00
IUUC-Aly-006508	Arabidopsis lyrata	88.08	0.00e+00	1648.00
IUUC-Ath-007635	Arabidopsis thaliana	87.04	0.00e+00	1637.00
IUUC-Bol-016271	Brassica oleracea	86.10	0.00e+00	1623.00
IUUC-Bra-017758	Brassica rapa	85.75	0.00e+00	1622.00
IUUC-Mtr-058618	Medicago truncatula	93.93	0.00e+00	1714.00
IUUC-Oba-075760	Oryza barthii	83.03	0.00e+00	1561.00
IUUC-Obr-076163	Oryza brachyantha	83.08	0.00e+00	1563.00
IUUC-Ogl-077450	Oryza glaberrima	83.91	0.00e+00	1588.00
IUUC-Ogu-078994	Oryza glumaepatula	83.03	0.00e+00	1560.00
IUUC-Oin-079211	Oryza indica	86.00	0.00e+00	1521.00
IUUC-Olo-080731	Oryza longistaminata	82.07	0.00e+00	1541.00
IUUC-Oni-082324	Oryza nivara	83.03	0.00e+00	1560.00
IUUC-Oru-084829	Oryza rufipogon	83.15	0.00e+00	1562.00
IUUC-Osa-086026	Oryza sativa	88.24	0.00e+00	1576.00
IUUC-Ppe-101470	Prunus persica	90.38	0.00e+00	1702.00
IUUC-Stu-112906	Solanum tuberosum	85.73	0.00e+00	1482.00
IUUC-Tae-125292	Triticum aestivum	83.37	0.00e+00	1589.00
IUUC-Tur-126283	Triticum urartu	74.81	0.00e+00	1397.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence