iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-017924

Ensembl Protein ID

Bra031757.1-P

UniProt Accession

M4ESH8; M4ESH8_BRARP

Protein Name

Katanin p80 WD40 repeat-containing subunit B1 homolog

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra031757	Bra031757.1	Bra031757.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.00e-31	106.7	657	695
UBD/Beta-Prp	6.70e-49	167.7	568	770

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt +++ ++f +d + lvsG+ D+++k+WD++ g+ll+
   Q: 657  GHTRGISTVKFtPDgRWLVSGGLDNVVKIWDITAGKLLH 695
           8***********99999******************9987 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvv 140
           l+sl gh++++ +v+f++++ + + g++ ++ik+w+l+  k v+ ++gh ++  +l+f+p g++l+sGs+d t+++wd++++ c++ t +gh++ +
   Q: 568  LQSLCGHTSPIDSVTFNSEEALVLAGASSGVIKLWNLQEAKVVRGFTGHISNCSALEFHPFGQYLASGSSDATLKIWDIRKKGCIQ-TYKGHTRGI 662
           799***********************************************************************************.********* PP
   S: 141  ncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnder 236
           ++v++ pdg+ lvsG+lD++v++Wd+  gkll++++  h+++++sl++++  + l++gs d+tvk+wdl+t e + + +   + v+s++f+p++  
   Q: 663  STVKFTPDGRWLVSGGLDNVVKIWDITAGKLLHEFKF-HDGPIRSLDYHPLEFLLATGSADRTVKFWDLETFELIGSTRPEATGVRSIAFHPDGRT 757
           ************************************9.*****************************************************99999 PP
   S: 237  lvsgssDgsiriWd 250
           l +g  D s++++ 
   Q: 758  LFCG-LDDSLKVYS 770
           9998.577888864 PP

Organism

Brassica rapa

Functional Description
(View)

May participate in a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.

Protein Sequence
(Fasta)

MPFSAGVTNL RDVSAINNLY ITLGAPSLSH WLAFGGDPCG EKWQGVVCDS SNITEIKDGT 60
PFNTSIITPP PPAVVPPPPT TTTHRSPPPV THIPPGSTVP PAPFAPFVPL QLTPPLPSPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCATTCT CGGCTGGAGT CACTAATCTA CGAGATGGTA ATAATCCCTC TTCTCCTGTC 60
TGCAAGTTTC CACTTCTGGT TTTGCTTTGT CTGTTTAAAT TTTTTGGTTT ATTGAACTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0472--Membrane
KW-0493--Microtubule
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR003143--Cyt_cd1_C
IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13925--Katanin_con80
PF00069--Pkinase
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0005524--F:ATP binding
GO:0004672--F:protein kinase activity
GO:0051013--P:microtubule severing

Orthology

iUUCD ID

Species

Identity

E-value

Score

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence