iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.60e-32	112.3	184	256

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceenss 74
           +peef+CpIslelM+dPv+++sG+ty+r++I+kwl+ g+ tcP+t+++lt++ ++Pn++lr+li +wce+n++
   Q: 184  PPEEFRCPISLELMTDPVIVSSGQTYERECIKKWLEGGHLTCPKTQETLTSDIMTPNYVLRSLIAQWCESNGI 256
           59********************************************************************987 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Functions as an E3 ubiquitin ligase.

Protein Sequence
(Fasta)

MLRICFLSLA MLAKFTWCVL ERDQVMVKFQ KVTSLLEQAL SIIPYENLEI SDELKEQVEL 60
VLVQLRRSLG KRGGDVYDDE LYKDVLSLYS GRGSVMESDM VRRVAEKLQL MTITDLTQES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCTTTGTTA TCTGTTAAGC AATCGCTTCT TCATGCTAAG GATTTGCTTT CTTTCGTTAG 60
CCATGTTAGC AAAATTTACC TGGTGTGTGA GTATTTCGAT TCTAAACATA CTTAGATCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000225--Armadillo
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50176--ARM_REPEAT
PS51698--U_BOX

Pfam

PF00514--Arm
PF04564--U-box

SMART

SM00185--ARM
SM00504--Ubox

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006566	Arabidopsis lyrata	90.12	0.00e+00	971.00
IUUC-Bol-015915	Brassica oleracea	78.53	0.00e+00	853.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence