• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Cel-018142
UUCD1 version UUC-CaE-00368
Ensembl Protein ID F10C5.1
UniProt Accession Q19294; CDC23_CAEEL
Genbank Protein ID CCD69151.1
Protein Name Cell division cycle protein 23 homolog; Anaphase-promoting complex subunit 8; Metaphase-to-anaphase transition defect protein 3
Genbank Nucleotide ID FO081107
Gene Name mat-3; apc-8; cdc-23; pod-4; vex-2; F10C5.1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00003134 F10C5.1 F10C5.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexPINAMentha
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/APC_C/APC_C 37.08 1.00e-79 295.00 IUUC-Hsa-045713
E3 adaptor/Cullin RING/APC_C/APC_C 35.93 3.00e-43 171.00 IUUC-Sce-106199
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (PubMed:11861581, PubMed:15238519). The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins (PubMed:11861581). Developmental role in early embryogenesis and the metaphase to anaphase transition in oocyte and spermatocyte meiosis and mitosis in germ cells (PubMed:11134076, PubMed:11861581, PubMed:15238519). Required for embryonic anterior-posterior axis formation (PubMed:11832245). Plays a role in regulating the abundance of glr-1 receptors in postmitotic neurons, which may in turn control animal locomotion (PubMed:15556870). Involved in regulating GABA neurotransmitter release at neuromuscular junctions in GABA motor neurons (PubMed:24321454).
 Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (PubMed:11861581, PubMed:15238519). The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins (PubMed:11861581). Developmental role in early embryogenesis and the metaphase to anaphase transition in oocyte and spermatocyte meiosis and mitosis in germ cells (PubMed:11134076, PubMed:11861581, PubMed:15238519). Required for embryonic anterior-posterior axis formation (PubMed:11832245). Plays a role in regulating the abundance of glr-1 receptors in postmitotic neurons, which may in turn control animal locomotion (PubMed:15556870). Involved in regulating GABA neurotransmitter release at neuromuscular junctions in GABA motor neurons (PubMed:24321454).
Protein Sequence
(Fasta)
MNVSFSTPVQ NSTASRLALI QQAAARSGAL PPAGQYRGSK LSPFDVSQMS GVSISMVERA 60
KINGPEFVEE LEWLRQQTTS RCFLDAEMWT NEILAHLPDK WCAPNTLNLY NQVSELVLDN 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018142|E3,APC_C|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGAACAGAA TGAACGTGAG TTTTTCAACT CCCGTGCAAA ACTCAACGGC CAGTCGACTT 60
GCGTTGATTC AACAGGTGAG AAAAAGCCCG AAAATTGAGC GAAAATTTGA ATTTTCAGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018142|E3,APC_C|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0469--Meiosis
KW-0498--Mitosis
KW-0532--Neurotransmitter transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
KW-0813--Transport
KW-0833--Ubl conjugation pathway
Interpro

IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
PROSITE

PS50005--TPR
PS50293--TPR_REGION
Pfam

PF13181--TPR_8
SMART

SM00028--TPR
Gene Ontology

GO:0051301--P:cell division
GO:0051321--P:meiotic cell cycle
GO:0007067--P:mitotic nuclear division
GO:0007275--P:multicellular organism development
GO:0006836--P:neurotransmitter transport
GO:0016567--P:protein ubiquitination
KEGG cel:CELE_F10C5.1
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000540 Aegilops tauschii 35.05 6.00e-57 214.00
IUUC-Aml-002139 Ailuropoda melanoleuca 36.84 6.00e-83 300.00
IUUC-Atr-002658 Amborella trichopoda 30.40 4.00e-62 231.00
IUUC-Apl-004020 Anas platyrhynchos 37.50 4.00e-80 290.00
IUUC-Aca-005101 Anolis carolinensis 36.45 2.00e-81 295.00
IUUC-Aly-006437 Arabidopsis lyrata 31.30 1.00e-63 236.00
IUUC-Ath-006712 Arabidopsis thaliana 31.30 6.00e-63 233.00
IUUC-Ago-007953 Ashbya gossypii 33.33 5.00e-49 187.00
IUUC-Acl-008166 Aspergillus clavatus 32.04 8.00e-50 190.00
IUUC-Afl-008420 Aspergillus flavus 31.39 2.00e-49 189.00
IUUC-Afu-009028 Aspergillus fumigatus 31.69 7.00e-49 187.00
IUUC-Ani-009390 Aspergillus nidulans 32.32 3.00e-51 195.00
IUUC-Ang-009704 Aspergillus niger 31.47 2.00e-53 202.00
IUUC-Aor-009990 Aspergillus oryzae 31.11 3.00e-49 188.00
IUUC-Ate-010510 Aspergillus terreus 31.25 1.00e-47 183.00
IUUC-Ame-011724 Astyanax mexicanus 34.27 1.00e-68 252.00
IUUC-Bgr-012007 Blumeria graminis 26.52 4.00e-41 161.00
IUUC-Bta-013310 Bos taurus 36.84 6.00e-83 300.00
IUUC-Bci-013833 Botrytis cinerea 27.81 1.00e-43 169.00
IUUC-Bdi-014957 Brachypodium distachyon 35.04 5.00e-61 227.00
IUUC-Bol-016105 Brassica oleracea 31.89 3.00e-65 241.00
IUUC-Bra-017168 Brassica rapa 32.69 1.00e-59 222.00
IUUC-Cja-019339 Callithrix jacchus 36.03 2.00e-82 298.00
IUUC-Cfa-020690 Canis familiaris 36.84 6.00e-83 300.00
IUUC-Cpo-021859 Cavia porcellus 36.84 2.00e-83 301.00
IUUC-Cre-022698 Chlamydomonas reinhardtii 30.94 2.00e-42 166.00
IUUC-Csa-024176 Chlorocebus sabaeus 37.04 3.00e-83 301.00
IUUC-Cho-024903 Choloepus hoffmanni 36.98 5.00e-69 253.00
IUUC-Cin-025468 Ciona intestinalis 32.39 2.00e-62 232.00
IUUC-Csv-026223 Ciona savignyi 37.03 1.00e-68 253.00
IUUC-Cgl-026453 Colletotrichum gloeosporioides 28.31 2.00e-40 159.00
IUUC-Cne-027038 Cryptococcus neoformans 28.03 1.00e-50 193.00
IUUC-Cme-027161 Cyanidioschyzon merolae 33.16 1.00e-53 202.00
IUUC-Dre-027972 Danio rerio 35.28 2.00e-78 285.00
IUUC-Dno-029164 Dasypus novemcinctus 36.84 5.00e-83 300.00
IUUC-Dor-030344 Dipodomys ordii 41.62 1.00e-79 289.00
IUUC-Dse-031277 Dothistroma septosporum 38.95 3.00e-38 150.00
IUUC-Dme-031895 Drosophila melanogaster 32.46 8.00e-74 270.00
IUUC-Ete-032942 Echinops telfairi 34.95 3.00e-75 274.00
IUUC-Eca-034355 Equus caballus 37.04 8.00e-83 300.00
IUUC-Eeu-035313 Erinaceus europaeus 41.67 2.00e-23 102.00
IUUC-Fca-035799 Felis catus 37.58 2.00e-83 301.00
IUUC-Fal-037373 Ficedula albicollis 36.66 6.00e-82 296.00
IUUC-Fox-037722 Fusarium oxysporum 31.42 1.00e-39 156.00
IUUC-Fso-038295 Fusarium solani 30.99 5.00e-39 154.00
IUUC-Gmo-039241 Gadus morhua 35.27 5.00e-76 277.00
IUUC-Ggr-039994 Gaeumannomyces graminis 30.93 4.00e-38 151.00
IUUC-Gga-040280 Gallus gallus 37.37 4.00e-81 294.00
IUUC-Gac-042265 Gasterosteus aculeatus 34.77 1.00e-80 292.00
IUUC-Gma-043161 Glycine max 30.74 8.00e-63 233.00
IUUC-Ggo-044898 Gorilla gorilla 39.75 5.00e-83 300.00
IUUC-Hsa-045713 Homo sapiens 37.04 2.00e-83 301.00
IUUC-Hvu-047296 Hordeum vulgare 33.96 1.00e-59 222.00
IUUC-Itr-048205 Ictidomys tridecemlineatus 37.04 5.00e-83 300.00
IUUC-Kpa-049344 Komagataella pastoris 43.33 6.00e-41 160.00
IUUC-Lch-049878 Latimeria chalumnae 36.44 1.00e-80 292.00
IUUC-Lpe-050917 Leersia perrieri 34.50 2.00e-59 222.00
IUUC-Loc-052893 Lepisosteus oculatus 37.84 7.00e-59 220.00
IUUC-Lma-053031 Leptosphaeria maculans 30.77 5.00e-46 177.00
IUUC-Laf-053888 Loxodonta africana 37.04 2.00e-83 301.00
IUUC-Mcc-055617 Macaca mulatta 35.02 6.00e-72 263.00
IUUC-Meu-056377 Macropus eugenii 36.83 5.00e-71 260.00
IUUC-Mor-057030 Magnaporthe oryzae 31.39 3.00e-39 155.00
IUUC-Mpo-057558 Magnaporthe poae 30.65 1.00e-38 153.00
IUUC-Mtr-058778 Medicago truncatula 30.36 7.00e-66 243.00
IUUC-Mla-058861 Melampsora laricipopulina 31.49 1.00e-34 139.00
IUUC-Mga-059809 Meleagris gallopavo 36.90 2.00e-81 295.00
IUUC-Mvi-060381 Microbotryum violaceum 35.74 2.00e-45 176.00
IUUC-Mmr-060669 Microcebus murinus 36.23 2.00e-75 275.00
IUUC-Mdo-062293 Monodelphis domestica 39.85 5.00e-80 290.00
IUUC-Mmu-064261 Mus musculus 35.80 1.00e-82 299.00
IUUC-Mac-065082 Musa acuminata 35.85 1.00e-58 219.00
IUUC-Mpu-066465 Mustela putorius furo 30.20 4.00e-50 191.00
IUUC-Mlu-067770 Myotis lucifugus 36.64 3.00e-83 301.00
IUUC-Nfi-068311 Neosartorya fischeri 31.42 2.00e-48 186.00
IUUC-Ncr-068653 Neurospora crassa 31.61 4.00e-36 144.00
IUUC-Nle-069036 Nomascus leucogenys 36.84 3.00e-83 301.00
IUUC-Opr-070229 Ochotona princeps 35.34 7.00e-53 199.00
IUUC-Ont-072218 Oreochromis niloticus 35.70 4.00e-81 294.00
IUUC-Ocu-073869 Oryctolagus cuniculus 36.84 2.00e-83 301.00
IUUC-Oba-075863 Oryza barthii 34.04 2.00e-59 222.00
IUUC-Obr-076071 Oryza brachyantha 34.77 4.00e-60 224.00
IUUC-Ogl-077026 Oryza glaberrima 35.17 7.00e-51 193.00
IUUC-Ogu-078601 Oryza glumaepatula 34.04 8.00e-60 223.00
IUUC-Oin-079443 Oryza indica 34.04 1.00e-59 223.00
IUUC-Olo-080836 Oryza longistaminata 34.04 4.00e-59 221.00
IUUC-Ome-081640 Oryza meridionalis 34.04 3.00e-59 221.00
IUUC-Oni-083014 Oryza nivara 34.04 2.00e-59 222.00
IUUC-Opu-083788 Oryza punctata 34.04 2.00e-59 222.00
IUUC-Oru-085205 Oryza rufipogon 34.04 1.00e-59 223.00
IUUC-Osa-085809 Oryza sativa 34.04 1.00e-59 223.00
IUUC-Ola-087272 Oryzias latipes 34.86 9.00e-78 283.00
IUUC-Olu-087775 Ostreococcus lucimarinus 32.14 9.00e-52 196.00
IUUC-Oga-088234 Otolemur garnettii 37.04 7.00e-83 300.00
IUUC-Oar-089533 Ovis aries 36.84 6.00e-83 300.00
IUUC-Ptr-090956 Pan troglodytes 36.84 2.00e-83 301.00
IUUC-Pan-091781 Papio anubis 37.04 3.00e-83 301.00
IUUC-Psi-093533 Pelodiscus sinensis 37.11 2.00e-82 299.00
IUUC-Pma-094153 Petromyzon marinus 36.90 6.00e-79 286.00
IUUC-Pno-095099 Phaeosphaeria nodorum 40.86 4.00e-41 161.00
IUUC-Ppa-095917 Physcomitrella patens 32.38 2.00e-60 225.00
IUUC-Pfo-096378 Poecilia formosa 35.22 8.00e-82 296.00
IUUC-Pab-098457 Pongo abelii 36.84 1.00e-83 302.00
IUUC-Pop-099359 Populus trichocarpa 32.19 2.00e-59 221.00
IUUC-Pca-100406 Procavia capensis 45.96 4.00e-57 214.00
IUUC-Ppe-101636 Prunus persica 31.22 5.00e-61 227.00
IUUC-Pva-103102 Pteropus vampyrus 36.84 3.00e-83 301.00
IUUC-Pgr-103324 Puccinia graminis 28.30 9.00e-45 173.00
IUUC-Ptt-103755 Puccinia triticina 33.33 1.00e-45 176.00
IUUC-Pte-104290 Pyrenophora teres 31.88 3.00e-44 172.00
IUUC-Pyt-104739 Pyrenophora triticirepentis 32.35 8.00e-45 173.00
IUUC-Rno-105205 Rattus norvegicus 35.79 3.00e-81 294.00
IUUC-Sce-106199 Saccharomyces cerevisiae 37.22 3.00e-44 172.00
IUUC-Sha-107218 Sarcophilus harrisii 37.16 4.00e-80 290.00
IUUC-Sja-107667 Schizosaccharomyces japonicus 29.04 1.00e-53 202.00
IUUC-Spo-108380 Schizosaccharomyces pombe 29.91 2.00e-53 202.00
IUUC-Smo-109350 Selaginella moellendorffii 33.33 1.00e-51 196.00
IUUC-Sit-110418 Setaria italica 31.43 1.00e-63 236.00
IUUC-Sly-111724 Solanum lycopersicum 30.87 6.00e-59 220.00
IUUC-Stu-112247 Solanum tuberosum 31.96 6.00e-51 194.00
IUUC-Sar-113502 Sorex araneus 42.58 8.00e-71 259.00
IUUC-Sbi-113784 Sorghum bicolor 29.49 6.00e-64 237.00
IUUC-Sre-115116 Sporisorium reilianum 31.46 4.00e-38 151.00
IUUC-Ssc-115914 Sus scrofa 36.84 3.00e-83 301.00
IUUC-Tgu-117390 Taeniopygia guttata 37.32 1.00e-81 295.00
IUUC-Tru-118703 Takifugu rubripes 34.17 7.00e-80 290.00
IUUC-Tsy-118972 Tarsius syrichta 37.84 3.00e-50 191.00
IUUC-Tni-119710 Tetraodon nigroviridis 33.33 1.00e-78 286.00
IUUC-Tca-121327 Theobroma cacao 31.35 2.00e-61 229.00
IUUC-Tre-121974 Trichoderma reesei 29.87 5.00e-38 151.00
IUUC-Tvi-122260 Trichoderma virens 29.97 7.00e-38 150.00
IUUC-Tae-124866 Triticum aestivum 28.93 1.00e-20 92.80
IUUC-Tme-127161 Tuber melanosporum 29.70 8.00e-51 193.00
IUUC-Tbe-127932 Tupaia belangeri 36.98 1.00e-66 246.00
IUUC-Ttr-129091 Tursiops truncatus 35.85 5.00e-83 300.00
IUUC-Uma-129376 Ustilago maydis 31.15 1.00e-38 153.00
IUUC-Vda-129821 Verticillium dahliae 25.83 1.00e-38 153.00
IUUC-Vpa-130644 Vicugna pacos 35.85 5.00e-83 300.00
IUUC-Vvi-130971 Vitis vinifera 30.36 4.00e-60 224.00
IUUC-Xtr-132050 Xenopus tropicalis 37.04 3.00e-78 285.00
IUUC-Xma-133078 Xiphophorus maculatus 35.22 2.00e-81 295.00
IUUC-Yli-134413 Yarrowia lipolytica 30.70 4.00e-52 197.00
IUUC-Zma-135224 Zea mays 30.88 1.00e-61 229.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved