iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010772

Ensembl Protein ID

ENSAMXP00000022009.1

UniProt Accession

W5LPX9; W5LPX9_ASTMX

Genbank Protein ID

ENSAMXP00000022009

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01022509

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000021376.1	ENSAMXT00000022009.1	ENSAMXP00000022009.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.10e-29	99.7	138	175
UBD/Beta-Prp	3.60e-41	141.5	2	319
ULD/UBL/SUMO	2.40e-51	172.6	488	573

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gHtd v +l +  d t  +sGs Dgti++W+l +++++
   Q: 138  GHTDNVKSLLLhRDgTQCLSGSSDGTIRLWSLGQQRCI 175
           8********88*888*****************999997 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls.........tgkc 86
           +hh++ ++++    +++ l+++s d t+kvw++++g ++++l  h++ v+a+ + +d+++ ++++ Dr i +wd++         +  +
   Q: 2    EHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNtltaltasnNTVT 90
           78999999888888999999999999999999999999999999999999999999999999999999999999999999999888889 PP
   S: 87   vhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl 175
           +++l+g++ds++sl++++ g ++vsGs  +++rvwd +t  +l   l+gh++ v ++ +h dg  + sGs D+t+rlW+l +++++ t 
   Q: 91   TSSLSGNKDSIYSLAMNQMGTVIVSGSTEKVLRVWDPRTCAKLM-KLKGHTDNVKSLLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATY 178
           99999999999999999999999999999999999999999999.99999999999999999999999999999999999999999999 PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs....pnderlvsgssDgsiriW........... 249
           +  h++ v  l++++  +++ sg++d+++   dl++ ++ +   + +++v+ ++++    p + + vs++   +++ W           
   Q: 179  RV-HDEGVWALQVNEAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDrsadPPSAIWVSTT-KSTVNKWslkgihnfrts 265
           98.9999999999999999999999999999999999977777778899999999988755566666665.788999955555544444 PP
   S: 250  ..dlrsgdllktlqlhn...................ssvisvavlsfg.dnvlvlgsedskvniwkl 294
                                                  + ++++ ++ ++++++ + ++++ +w++
   Q: 266  gdY-------------DndcstpltplctqpdqvikGGASIIQCHILNdKRHILTKDTNNNIAYWDV 319
           430.............234444445555566568885555555544554667777777999999986 PP

ULD/UBL/SUMO

   S: 1    eskffkapvslkvagqdGsevlfklklsa....qlkklmeavYvkrinldensvrfvfngqkireqetpeelevededkiellcqk 82
           ++kf+k+p++l++++++G+++l+k++lsa    q++k+me+vY+k+inld +s++  + g+k++eq+ +e+++v++e+kiellcq+
   Q: 488  MPKFNKIPFYLQPHSSSGAKTLKKDRLSAsdmlQVRKVMEHVYEKIINLDSESQTGGSAGEKPSEQKEEEDMAVLAEEKIELLCQD 573
           8***********************************************************************************95 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MEHHTDWVND IVLCCNGKTL ISASSDTTVK VWNAHKGFCM STLRTHKDYV KALAYAKDKE 60
LVASAGLDRQ IFLWDVNTLT ALTASNNTVT TSSLSGNKDS IYSLAMNQMG TVIVSGSTEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCAATGTGC AATCTTGGGG TAATGAGCAA ATTATCTTAA TATTTTTATT CAGGTTTCTT 60
ATGTGATCAG AGATGAAGTG GAGAAGTACA ACCGCAATGG AGTCAATGCG CTGCAACTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR021772--DUF3337
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF11816--DUF3337
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003709	Anas platyrhynchos	95.85	8.00e-156	542.00
IUUC-Aly-005464	Arabidopsis lyrata	42.00	5.00e-87	315.00
IUUC-Ath-006969	Arabidopsis thaliana	41.63	4.00e-83	302.00
IUUC-Acl-008203	Aspergillus clavatus	29.89	6.00e-52	199.00
IUUC-Cre-022779	Chlamydomonas reinhardtii	29.97	1.00e-39	159.00
IUUC-Cgl-026540	Colletotrichum gloeosporioides	28.25	7.00e-17	83.20
IUUC-Eeu-034894	Erinaceus europaeus	92.29	0.00e+00	714.00
IUUC-Fca-035619	Felis catus	94.54	0.00e+00	771.00
IUUC-Fox-037907	Fusarium oxysporum	33.71	6.00e-35	143.00
IUUC-Fso-038101	Fusarium solani	35.61	1.00e-35	145.00
IUUC-Lma-053025	Leptosphaeria maculans	37.17	5.00e-42	166.00
IUUC-Meu-056840	Macropus eugenii	76.51	2.00e-141	496.00
IUUC-Mac-065217	Musa acuminata	36.62	5.00e-94	338.00
IUUC-Mpu-065999	Mustela putorius furo	94.69	0.00e+00	679.00
IUUC-Nfi-068416	Neosartorya fischeri	30.22	2.00e-51	197.00
IUUC-Ome-081368	Oryza meridionalis	41.40	1.00e-90	327.00
IUUC-Olu-087710	Ostreococcus lucimarinus	31.89	1.00e-73	270.00
IUUC-Pno-095085	Phaeosphaeria nodorum	37.55	7.00e-42	166.00
IUUC-Pca-100458	Procavia capensis	67.91	9.00e-92	331.00
IUUC-Pte-104181	Pyrenophora teres	38.29	9.00e-43	169.00
IUUC-Pyt-104439	Pyrenophora triticirepentis	37.92	2.00e-42	167.00
IUUC-Ssl-108542	Sclerotinia sclerotiorum	28.95	1.00e-41	165.00
IUUC-Sly-111099	Solanum lycopersicum	34.52	8.00e-96	344.00
IUUC-Sar-113408	Sorex araneus	95.64	2.00e-175	609.00
IUUC-Sre-114998	Sporisorium reilianum	40.07	4.00e-51	197.00
IUUC-Tme-126932	Tuber melanosporum	32.31	2.00e-50	194.00
IUUC-Vpa-130553	Vicugna pacos	93.64	0.00e+00	805.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence