iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mac-064754

Ensembl Protein ID

GSMUA_Achr8P12630_001

UniProt Accession

M0TPW6; M0TPW6_MUSAM

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSMUA_Achr8G12630_001	GSMUA_Achr8T12630_001	GSMUA_Achr8P12630_001

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.80e-24	84.0	262	292
E3 activity/RING/U-box	6.70e-16	59.0	1	68
UBD/Beta-Prp	8.40e-47	160.6	225	425

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH+ +vt+++f ++  l+v+Gs D+t++vW 
   Q: 262  GHSKKVTSVKFvPGnELIVTGSSDKTVRVWQ 292
           8***********777***************6 PP

E3 activity/RING/U-box

   S: 6    flCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           ++C+Is+e+++dPv ++ sG  ++r+ Ie ++as gk cP+t+++lt +dl+P +t + +  + +++ s
   Q: 1    MICAISGEVPEDPVLSKkSGLLFERRLIEHHIASHGK-CPITKEELTMDDLIPVKTNKVVKPRPLQAAS 68
           58***********************************.********************99998888765 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvw...dlstgkcvhtlkghedsv 97
           i ++++  +k+++atg+ d    +++  +g++l++lsgh+++vt+vkf p  +++vtgs+D+t++vw   +  +++c h+++ h+++v
   Q: 225  ILSIDIDASKDIIATGGIDTNGVLFNRASGQMLSTLSGHSKKVTSVKFVPGNELIVTGSSDKTVRVWqgtENGNYDCQHVMRDHTAEV 312
           4446677788888888888888888888888888888888888888888888888888888888888655445888888888888888 PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
            +++++++++++v++s d+t   +dl+tg+cl +  ++ +++  +++++hpdg +l +G++  +v++Wd+k+++ + ++ g h +sv+
   Q: 313  QAVTVHATQKYFVTASMDNTWCFYDLSTGSCLTQvGEASTEEGYTSASFHPDGLILGTGTTGAIVKIWDVKSQSNVAKFDG-HVGSVT 399
           888888888888888888888888888888888865556666788888888888888888888888888888888888888.888888 PP
   S: 185  slsfdsngkelvsgsldgtvklwdlqt 211
            +sf++ng +l+++++dg vklwdl++
   Q: 400  AMSFSENGYFLATAAMDG-VKLWDLRK 425
           888888888888888887.78888875 PP

Organism

Musa acuminata

Protein Sequence
(Fasta)

MICAISGEVP EDPVLSKKSG LLFERRLIEH HIASHGKCPI TKEELTMDDL IPVKTNKVVK 60
PRPLQAASIP GLLGMFQNEW DALMLSSFAL EQQLHTARQE LSHALYQHDA ACRVIARLKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATCTGTG CGAGTACGCC CCTGTCCCTT CCTTCGTCTG GAAACCCTAG GGTTTGTTCT 60
CTTTCTTTTC CCGTTCGATT TGGTGTTTCT AACATCACTC CCCTCTCTTC AATGTAGTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR013915--Pre-mRNA_splic_Prp19
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08606--Prp19
PF04564--U-box
PF00400--WD40

SMART

SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

mus:103993155

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003686	Anas platyrhynchos	42.45	1.00e-82	299.00
IUUC-Ago-007879	Ashbya gossypii	26.60	5.00e-30	125.00
IUUC-Acl-008335	Aspergillus clavatus	34.87	2.00e-62	232.00
IUUC-Ame-011561	Astyanax mexicanus	42.27	3.00e-43	167.00
IUUC-Cho-025065	Choloepus hoffmanni	38.80	4.00e-44	171.00
IUUC-Dor-030150	Dipodomys ordii	45.56	1.00e-41	163.00
IUUC-Kpa-049195	Komagataella pastoris	48.03	6.00e-22	98.20
IUUC-Lpe-050976	Leersia perrieri	80.53	0.00e+00	896.00
IUUC-Meu-056161	Macropus eugenii	43.10	3.00e-50	192.00
IUUC-Oan-073498	Ornithorhynchus anatinus	34.23	6.00e-35	140.00
IUUC-Olu-087757	Ostreococcus lucimarinus	44.75	3.00e-117	414.00
IUUC-Ppa-095841	Physcomitrella patens	70.11	0.00e+00	761.00
IUUC-Sit-109873	Setaria italica	81.54	0.00e+00	895.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence