iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026955

Ensembl Protein ID

AAW42987

UniProt Accession

Q5KIZ8; Q55TE0; Q5KIZ8_CRYNJ

Genbank Protein ID

AAW42987.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AE017344

Gene Name

CND01170

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CND01170	AAW42987	AAW42987

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
DUB/UCH	35.40	2.00e-43	170.00	IUUC-Spo-108371

Active Site

Position(s)	Description	Evidence
92	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
177	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Organism

Cryptococcus neoformans

Protein Sequence
(Fasta)

MADDPSGWSL TESDPQVFTQ LLKDLGVNGL QVDDLYSLDA ETLATLKPIH ALIFLFKYVA 60
PDAESAQESA GVEVDPLDNG VWFANQVINN SCGTLAALNA VMNIKPQQSV HERESIKLGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCACGACTAA CAATGGCAGA CGACCCTTCA GGCTGGTCGC TCACAGAGTC AGACCCCCAG 60
GTATTCACCC AGCTGCTAAA GGACTTGGGC GTAAACGGAT TGCAAGTAGT CAGTCATACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

cne:CND01170

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	34.62	2.00e-48	184.00
IUUC-Aml-001866	Ailuropoda melanoleuca	38.87	6.00e-54	202.00
IUUC-Atr-002966	Amborella trichopoda	31.05	7.00e-38	149.00
IUUC-Apl-003306	Anas platyrhynchos	33.90	1.00e-47	181.00
IUUC-Aca-004763	Anolis carolinensis	37.50	2.00e-52	197.00
IUUC-Aly-005581	Arabidopsis lyrata	31.61	5.00e-40	155.00
IUUC-Ath-007283	Arabidopsis thaliana	33.05	2.00e-43	167.00
IUUC-Ago-007999	Ashbya gossypii	32.78	4.00e-36	143.00
IUUC-Acl-008231	Aspergillus clavatus	37.50	6.00e-49	185.00
IUUC-Afl-008557	Aspergillus flavus	35.64	3.00e-47	179.00
IUUC-Afu-008988	Aspergillus fumigatus	39.92	1.00e-48	184.00
IUUC-Ani-009420	Aspergillus nidulans	37.50	2.00e-53	200.00
IUUC-Ang-009859	Aspergillus niger	34.44	2.00e-45	174.00
IUUC-Aor-010145	Aspergillus oryzae	35.64	3.00e-47	179.00
IUUC-Ate-010347	Aspergillus terreus	37.45	7.00e-44	169.00
IUUC-Ame-010791	Astyanax mexicanus	35.21	5.00e-53	199.00
IUUC-Bgr-012298	Blumeria graminis	34.69	9.00e-38	148.00
IUUC-Bta-013251	Bos taurus	38.99	6.00e-54	202.00
IUUC-Bci-013786	Botrytis cinerea	35.56	3.00e-45	173.00
IUUC-Bdi-014132	Brachypodium distachyon	34.02	2.00e-47	180.00
IUUC-Bol-015611	Brassica oleracea	34.29	9.00e-44	168.00
IUUC-Bra-017769	Brassica rapa	34.57	7.00e-44	169.00
IUUC-Cel-018604	Caenorhabditis elegans	36.76	2.00e-54	204.00
IUUC-Cja-019768	Callithrix jacchus	34.87	3.00e-48	183.00
IUUC-Cfa-020207	Canis familiaris	38.87	6.00e-54	202.00
IUUC-Cpo-021925	Cavia porcellus	37.30	7.00e-51	192.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	32.63	3.00e-41	160.00
IUUC-Csa-023958	Chlorocebus sabaeus	38.68	6.00e-54	202.00
IUUC-Cho-024928	Choloepus hoffmanni	38.89	1.00e-08	52.00
IUUC-Cin-025771	Ciona intestinalis	35.84	2.00e-52	197.00
IUUC-Csv-026149	Ciona savignyi	37.58	2.00e-53	200.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	34.06	1.00e-39	154.00
IUUC-Cme-027104	Cyanidioschyzon merolae	29.28	1.00e-34	138.00
IUUC-Dre-027409	Danio rerio	35.21	2.00e-51	193.00
IUUC-Dno-028921	Dasypus novemcinctus	38.56	2.00e-53	200.00
IUUC-Dor-030891	Dipodomys ordii	27.94	6.00e-23	100.00
IUUC-Dse-031170	Dothistroma septosporum	37.54	3.00e-47	180.00
IUUC-Dme-031677	Drosophila melanogaster	37.80	2.00e-60	223.00
IUUC-Ete-032646	Echinops telfairi	30.62	7.00e-23	100.00
IUUC-Eca-033776	Equus caballus	38.44	2.00e-46	177.00
IUUC-Eeu-035305	Erinaceus europaeus	35.18	5.00e-27	112.00
IUUC-Fca-035846	Felis catus	35.84	1.00e-49	188.00
IUUC-Fal-037597	Ficedula albicollis	35.71	2.00e-44	170.00
IUUC-Fox-037670	Fusarium oxysporum	36.09	6.00e-40	155.00
IUUC-Fso-038243	Fusarium solani	36.05	3.00e-40	156.00
IUUC-Gmo-038499	Gadus morhua	35.00	9.00e-46	175.00
IUUC-Ggr-039975	Gaeumannomyces graminis	35.29	2.00e-37	147.00
IUUC-Gga-040904	Gallus gallus	36.86	2.00e-54	203.00
IUUC-Gac-042058	Gasterosteus aculeatus	36.68	1.00e-50	191.00
IUUC-Gma-043763	Glycine max	32.47	6.00e-41	159.00
IUUC-Ggo-044699	Gorilla gorilla	42.08	1.00e-48	184.00
IUUC-Hsa-046227	Homo sapiens	38.56	5.00e-54	202.00
IUUC-Hvu-047359	Hordeum vulgare	34.02	3.00e-49	187.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	35.71	4.00e-49	186.00
IUUC-Lch-049829	Latimeria chalumnae	37.30	8.00e-53	198.00
IUUC-Lpe-050899	Leersia perrieri	34.34	1.00e-44	171.00
IUUC-Loc-052264	Lepisosteus oculatus	37.19	1.00e-50	191.00
IUUC-Lma-053110	Leptosphaeria maculans	35.67	5.00e-37	146.00
IUUC-Laf-053639	Loxodonta africana	38.87	6.00e-54	202.00
IUUC-Mcc-055506	Macaca mulatta	38.68	5.00e-54	202.00
IUUC-Meu-056267	Macropus eugenii	30.80	3.00e-29	121.00
IUUC-Mor-057001	Magnaporthe oryzae	33.92	3.00e-41	160.00
IUUC-Mpo-057608	Magnaporthe poae	36.51	1.00e-27	114.00
IUUC-Mtr-057731	Medicago truncatula	32.01	2.00e-43	167.00
IUUC-Mla-059016	Melampsora laricipopulina	48.78	8.00e-50	187.00
IUUC-Mga-060178	Meleagris gallopavo	35.46	5.00e-47	179.00
IUUC-Mvi-060353	Microbotryum violaceum	38.37	3.00e-63	233.00
IUUC-Mmr-060738	Microcebus murinus	38.56	1.00e-53	201.00
IUUC-Mdo-062266	Monodelphis domestica	42.79	1.00e-42	164.00
IUUC-Mmu-063619	Mus musculus	39.18	2.00e-54	204.00
IUUC-Mac-065301	Musa acuminata	33.33	1.00e-45	174.00
IUUC-Mpu-066058	Mustela putorius furo	38.87	5.00e-54	202.00
IUUC-Mlu-067292	Myotis lucifugus	38.99	2.00e-54	203.00
IUUC-Nfi-068275	Neosartorya fischeri	37.17	8.00e-52	195.00
IUUC-Ncr-068713	Neurospora crassa	34.43	2.00e-48	184.00
IUUC-Nle-069013	Nomascus leucogenys	38.68	2.00e-54	204.00
IUUC-Opr-070628	Ochotona princeps	33.53	4.00e-43	166.00
IUUC-Ont-072688	Oreochromis niloticus	36.88	2.00e-50	190.00
IUUC-Oan-073004	Ornithorhynchus anatinus	40.37	6.00e-40	155.00
IUUC-Ocu-074303	Oryctolagus cuniculus	38.87	1.00e-53	202.00
IUUC-Oba-075002	Oryza barthii	33.73	3.00e-45	173.00
IUUC-Obr-076392	Oryza brachyantha	33.94	9.00e-44	168.00
IUUC-Ogl-077271	Oryza glaberrima	33.73	3.00e-45	173.00
IUUC-Ogu-078493	Oryza glumaepatula	33.73	5.00e-45	172.00
IUUC-Oin-080084	Oryza indica	33.73	5.00e-45	172.00
IUUC-Olo-080803	Oryza longistaminata	33.43	1.00e-44	171.00
IUUC-Ome-081146	Oryza meridionalis	33.83	6.00e-45	172.00
IUUC-Oni-082146	Oryza nivara	33.73	5.00e-45	172.00
IUUC-Opu-083633	Oryza punctata	34.35	5.00e-44	169.00
IUUC-Oru-084789	Oryza rufipogon	33.73	5.00e-45	172.00
IUUC-Osa-086196	Oryza sativa	33.73	5.00e-45	172.00
IUUC-Ola-087126	Oryzias latipes	37.19	1.00e-51	194.00
IUUC-Olu-087665	Ostreococcus lucimarinus	38.54	1.00e-48	184.00
IUUC-Oga-089140	Otolemur garnettii	35.26	3.00e-49	186.00
IUUC-Oar-090296	Ovis aries	38.56	2.00e-52	197.00
IUUC-Ptr-090566	Pan troglodytes	38.56	5.00e-54	202.00
IUUC-Pan-092052	Papio anubis	38.68	5.00e-54	202.00
IUUC-Psi-093723	Pelodiscus sinensis	36.39	3.00e-45	173.00
IUUC-Pma-094568	Petromyzon marinus	39.25	2.00e-39	154.00
IUUC-Pno-095120	Phaeosphaeria nodorum	35.26	1.00e-41	161.00
IUUC-Ppa-095761	Physcomitrella patens	32.20	6.00e-43	166.00
IUUC-Pfo-096210	Poecilia formosa	36.88	9.00e-51	191.00
IUUC-Pab-098463	Pongo abelii	38.56	5.00e-54	202.00
IUUC-Pop-099109	Populus trichocarpa	32.09	3.00e-41	160.00
IUUC-Pca-100108	Procavia capensis	42.15	7.00e-47	179.00
IUUC-Ppe-101176	Prunus persica	33.04	1.00e-39	155.00
IUUC-Pva-102629	Pteropus vampyrus	42.50	1.00e-47	181.00
IUUC-Pgr-103419	Puccinia graminis	43.13	4.00e-62	229.00
IUUC-Pte-104207	Pyrenophora teres	37.36	1.00e-23	100.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	35.05	1.00e-44	171.00
IUUC-Rno-105579	Rattus norvegicus	34.45	7.00e-43	165.00
IUUC-Sha-106894	Sarcophilus harrisii	36.96	1.00e-40	157.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	35.33	7.00e-45	172.00
IUUC-Spo-108371	Schizosaccharomyces pombe	35.40	2.00e-44	170.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	33.96	9.00e-35	138.00
IUUC-Smo-109396	Selaginella moellendorffii	34.02	1.00e-41	161.00
IUUC-Sit-110630	Setaria italica	32.74	4.00e-46	176.00
IUUC-Sly-110972	Solanum lycopersicum	31.21	1.00e-39	154.00
IUUC-Stu-112185	Solanum tuberosum	32.01	2.00e-46	177.00
IUUC-Sar-113294	Sorex araneus	34.02	5.00e-44	169.00
IUUC-Sbi-113951	Sorghum bicolor	33.53	7.00e-45	172.00
IUUC-Ssc-115501	Sus scrofa	37.62	4.00e-48	182.00
IUUC-Tgu-117152	Taeniopygia guttata	35.71	2.00e-44	170.00
IUUC-Tru-118388	Takifugu rubripes	36.99	4.00e-51	192.00
IUUC-Tsy-119109	Tarsius syrichta	38.87	3.00e-54	203.00
IUUC-Tni-120048	Tetraodon nigroviridis	36.68	2.00e-51	194.00
IUUC-Tca-121750	Theobroma cacao	31.36	6.00e-43	165.00
IUUC-Tre-122130	Trichoderma reesei	36.62	9.00e-45	171.00
IUUC-Tvi-122284	Trichoderma virens	35.86	5.00e-39	152.00
IUUC-Tae-124082	Triticum aestivum	34.02	4.00e-49	186.00
IUUC-Tur-126366	Triticum urartu	29.82	6.00e-30	123.00
IUUC-Tme-127187	Tuber melanosporum	34.15	1.00e-45	174.00
IUUC-Tbe-127619	Tupaia belangeri	34.71	1.00e-32	131.00
IUUC-Ttr-128867	Tursiops truncatus	37.24	1.00e-35	141.00
IUUC-Vda-129912	Verticillium dahliae	37.63	3.00e-43	166.00
IUUC-Vpa-130552	Vicugna pacos	42.79	9.00e-44	168.00
IUUC-Vvi-130881	Vitis vinifera	32.39	1.00e-41	161.00
IUUC-Xtr-131934	Xenopus tropicalis	36.09	4.00e-53	199.00
IUUC-Xma-133312	Xiphophorus maculatus	36.88	1.00e-50	191.00
IUUC-Yli-134487	Yarrowia lipolytica	32.50	2.00e-44	170.00
IUUC-Zma-135462	Zea mays	31.16	1.00e-36	144.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence